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Search results 201 to 227 out of 227 for Dnd1

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Type Details Score
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
18155131 | -
First Author: Kedde M
Year: 2007
Journal: Cell
Title: RNA-binding protein Dnd1 inhibits microRNA access to target mRNA.
Volume: 131
Issue: 7
Pages: 1273-86
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Allele
Dnd1<em1Cpl> | MGI:7462384
Name: DND microRNA-mediated repression inhibitor 1; endonuclease-mediated mutation 1, Blanche Capel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Tg(CAG-cat,-Dnd1)1Ysa | MGI:7469605
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence, Reporter
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Allele
Gt(ROSA)26Sor<tm1(CAG-Dnd1)Matn> | MGI:6386785
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Angabin Matin
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence
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Publication
18160032 | -
First Author: Ketting RF
Year: 2007
Journal: Cell
Title: A dead end for microRNAs.
Volume: 131
Issue: 7
Pages: 1226-7
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Protein Domain
IPR034414 | DND1_RRM1
Type: Domain
Description: This entry represents the RNA recognition motif 1 (RRM1) of DND1, an RNA-binding protein that is essential for maintaining viable germ cells in vertebrates [, ]. It interacts with the 3'-untranslated region (3'-UTR) of multiple messenger RNAs (mRNAs) and prevents micro-RNA (miRNA) mediated repression of mRNA [, ]. For instance, DND1 binds cell cycle inhibitor, P27 (p27Kip1, CDKN1B), and cell cycle regulator and tumor suppressor, LATS2 (large tumor suppressor, homologue 2 of Drosophila) []. It helps maintain their protein expression through blocking the inhibitory function of microRNAs (miRNA) from these transcripts. DND1 may also impose another level of translational regulation to modulate expression of critical factors in embryonic stem (ES) cells. DND1 interacts specifically with apolipoprotein B editing complex 3 (APOBEC3), a multi-functional protein inhibiting retroviral replication. The DND1-APOBEC3 interaction may play a role in maintaining viability of germ cells and for preventing germ cell tumor development []. DND1 contains two conserved RNA recognition motifs (RRMs).
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Publication
31513344 | J:281756
First Author: Nunez L
Year: 2019
Journal: Genesis
Title: Generation of a novel mouse strain with conditional, cell-type specific, expression of DND1.
Volume: 57
Issue: 11-12
Pages: e23335
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Publication
21851623 | -
 
First Author: Zhu R
Year: 2011
Journal: BMC Mol Biol
Title: Transcripts that associate with the RNA binding protein, DEAD-END (DND1), in embryonic stem (ES) cells.
Volume: 12
Pages: 37
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Publication
29257950 | -
First Author: Gross-Thebing T
Year: 2017
Journal: Dev Cell
Title: The Vertebrate Protein Dead End Maintains Primordial Germ Cell Fate by Inhibiting Somatic Differentiation.
Volume: 43
Issue: 6
Pages: 704-715.e5
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Protein Domain
IPR044448 | DND1_DSRM
Type: Domain
Description: Dead end protein 1 (DND1) is an RNA-binding protein that is required for the survival of primordial germ cells (PGCs) and suppresses the formation of germ-cell tumors []. DND1 binds a UU(A/U) trinucleotide motif predominantly in the 3' untranslated regions of mRNA, and destabilizes target mRNAs []. It also counteracts the function of several microRNAs (miRNAs), which are inhibitors of gene expression, by binding mRNAs and prohibiting miRNAs from associating with their target sites []. DND1 contains two RNA recognition motifs (RRMs) and a C-terminal double-stranded RNA binding motif (DSRM) that is not sequence specific, but highly specific for dsRNAs of various origin and structure.This entry represents the DSRM of DND1.
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Protein
Q6VY05
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
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Publication
29222434 | J:269095
First Author: Kasowitz SD
Year: 2017
Journal: Sci Rep
Title: Embryonic lethality and defective male germ cell development in mice lacking UTF1.
Volume: 7
Issue: 1
Pages: 17259
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Publication
28870987 | J:245426
First Author: Aguero T
Year: 2017
Journal: Development
Title: Maternal Dead-end 1 promotes translation of nanos1 by binding the eIF3 complex.
Volume: 144
Issue: 20
Pages: 3755-3765
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Publication
22614019 | J:197235
First Author: Bhandari A
Year: 2013
Journal: Oncogene
Title: The Grainyhead transcription factor Grhl3/Get1 suppresses miR-21 expression and tumorigenesis in skin: modulation of the miR-21 target MSH2 by RNA-binding protein DND1.
Volume: 32
Issue: 12
Pages: 1497-507
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Publication
28185954 | J:255855
First Author: Cho SJ
Year: 2017
Journal: Biochim Biophys Acta
Title: Wip1 directly dephosphorylates NLK and increases Wnt activity during germ cell development.
Volume: 1863
Issue: 4
Pages: 1013-1022
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Publication
19861488 | J:162904
First Author: Yamaji M
Year: 2010
Journal: Reproduction
Title: Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3.
Volume: 139
Issue: 2
Pages: 381-93
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