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Search results 1 to 100 out of 112 for Sla2

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
84174 | SLA2
Type: gene
Organism: human
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Gene
499931 | Sla2
Type: gene
Organism: rat
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Gene
735438 | SLA2
Type: gene
Organism: chimpanzee
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Gene
485859 | SLA2
Type: gene
Organism: dog, domestic
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Gene
514398 | SLA2
Type: gene
Organism: cattle
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Gene
100858750 | SLA2
Type: gene
Organism: chicken
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Gene
702574 | SLA2
Type: gene
Organism: macaque, rhesus
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Gene
100495864 | sla2
Type: gene
Organism: frog, western clawed
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Protein Coding Gene
MGI:1925049 | Sla2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0024565 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026771 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026746 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026488 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1925049 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027195 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025950 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026465 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026603 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026570 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027251 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025684 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026020 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026009 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025487 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12527895 | J:81480
First Author: Loreto MP
Year: 2003
Journal: Oncogene
Title: Cloning and characterization of human Src-like adaptor protein 2 and a novel splice isoform, SLAP-2-v.
Volume: 22
Issue: 2
Pages: 266-73
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GXD Expression
GXD Expression
 
Probe: MGI:4428335
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828085
Age: embryonic day 14.5
Image: euxassay_019563_13
Specimen Label: euxassay_019563_13
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4428335
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828085
Age: embryonic day 14.5
Image: euxassay_019563_14
Specimen Label: euxassay_019563_14
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4428335
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828085
Age: embryonic day 14.5
Image: euxassay_019563_15
Specimen Label: euxassay_019563_15
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4428335
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828085
Age: embryonic day 14.5
Image: euxassay_019563_16
Specimen Label: euxassay_019563_16
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4428335
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828085
Age: embryonic day 14.5
Image: euxassay_019563_17
Specimen Label: euxassay_019563_17
Detected: true
Specimen Num: 5
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Publication
21220694 | J:169170
First Author: Liontos LM
Year: 2011
Journal: J Immunol
Title: The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation.
Volume: 186
Issue: 4
Pages: 1923-33
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Publication
27458164 | J:268117
First Author: Moharram SA
Year: 2016
Journal: Oncotarget
Title: Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling.
Volume: 7
Issue: 36
Pages: 57770-57782
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Publication
25301707 | J:220791
First Author: Cherpokova D
Year: 2015
Journal: Blood
Title: SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice.
Volume: 125
Issue: 1
Pages: 185-94
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Publication
11891219 | J:76854
First Author: Pandey A
Year: 2002
Journal: J Biol Chem
Title: A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling.
Volume: 277
Issue: 21
Pages: 19131-8
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Publication
12024036 | J:76785
First Author: Loreto MP
Year: 2002
Journal: Mol Cell Biol
Title: Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.
Volume: 22
Issue: 12
Pages: 4241-55
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:345476
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR030224 | Sla2_fam
Type: Family
Description: The Sla2 family, also known as Sla2p/HIP1/HIP1R family, includes Sla2 from budding yeasts [], End4 from fission yeasts [], and Huntingtin-interacting protein 1 (HIP1) and HIP1-related (HIP1R) from humans and mice []. They are adaptor proteins that link actin to clathrin and endocytosis in the clathrin-mediated endocytosis (CME) pathway. They contain the ENTH and ANTH (E/ANTH) domain that binds both inositol phospholipids and proteins and contributes to the nucleation and formation of clathrin coats on membranes []. They may bind to actin through their I/LWEQ (talin-like) domain [].
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Publication
14657269 | -
First Author: Legendre-Guillemin V
Year: 2004
Journal: J Cell Sci
Title: ENTH/ANTH proteins and clathrin-mediated membrane budding.
Volume: 117
Issue: Pt 1
Pages: 9-18
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Publication
20074057 | -
First Author: Gottfried I
Year: 2010
Journal: Biochem Soc Trans
Title: The Sla2p/HIP1/HIP1R family: similar structure, similar function in endocytosis?
Volume: 38
Issue: Pt 1
Pages: 187-91
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Publication
15827087 | -
First Author: Castagnetti S
Year: 2005
Journal: J Cell Sci
Title: End4/Sla2 is involved in establishment of a new growth zone in Schizosaccharomyces pombe.
Volume: 118
Issue: Pt 9
Pages: 1843-50
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Publication
14704157 | -
First Author: Baggett JJ
Year: 2003
Journal: Genetics
Title: The Sla2p talin domain plays a role in endocytosis in Saccharomyces cerevisiae.
Volume: 165
Issue: 4
Pages: 1661-74
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Publication
14732715 | -
First Author: Hyun TS
Year: 2004
Journal: J Biol Chem
Title: HIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3-phosphoinositides via epsin N-terminal homology domains.
Volume: 279
Issue: 14
Pages: 14294-306
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Protein
A0A0J9YV08
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: true
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Interaction Experiment
Pashkova N (2021)
Description: ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals.
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Protein
F7DCR9
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Publication
34821552 | -
   
First Author: Pashkova N
Year: 2021
Journal: Elife
Title: ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals.
Volume: 10
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Protein
A0A0J9YUA3
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: true
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Protein
A0A0G2JFU3
Organism: Mus musculus/domesticus
Length: 165  
Fragment?: true
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Protein
E9Q3C5
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Protein
Q8BPA2
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: false
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Protein
Q80UP1
Organism: Mus musculus/domesticus
Length: 682  
Fragment?: true
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Protein
Q8C303
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
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Protein
A0A0J9YUX9
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: true
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Protein
A0A1D5RMM7
Organism: Mus musculus/domesticus
Length: 402  
Fragment?: false
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Publication
10471698 | -
First Author: Zuk D
Year: 1999
Journal: Genetics
Title: Temperature-sensitive mutations in the Saccharomyces cerevisiae MRT4, GRC5, SLA2 and THS1 genes result in defects in mRNA turnover.
Volume: 153
Issue: 1
Pages: 35-47
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Protein
A0A1L1SVA8
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
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Protein
Q8VD75
Organism: Mus musculus/domesticus
Length: 1029  
Fragment?: false
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Protein
Q9JKY5
Organism: Mus musculus/domesticus
Length: 1068  
Fragment?: false
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Protein
Q9D689
Organism: Mus musculus/domesticus
Length: 1068  
Fragment?: false
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Protein
Q6P1F5
Organism: Mus musculus/domesticus
Length: 1068  
Fragment?: false
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Protein
Q6ZQ77
Organism: Mus musculus/domesticus
Length: 1083  
Fragment?: true
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Protein
Q8C9Z8
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: true
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Protein
Q3TKJ2
Organism: Mus musculus/domesticus
Length: 321  
Fragment?: true
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Protein
A2AIM2
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: true
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Protein Domain
IPR029922 | Sla1
Type: Family
Description: Sla1 is a fungal protein involved in coupling the actin cytoskeleton to the endocytic machinery during endocytosis. It binds to Sla2 (yeast Huntingtin interacting protein-1 HIP1), which plays a role in regulating actin dynamics and endocytosis []. It serves as the targeting signal recognition factor for NPFX(1,2)D-mediated endocytosis [].
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Protein Domain
IPR035800 | Sla1_SH3_1
Type: Domain
Description: Sla1 is a fungal protein involved in coupling the actin cytoskeleton to the endocytic machinery during endocytosis. It binds to Sla2 (yeast Huntingtin interacting protein-1 HIP1), which plays a role in regulating actin dynamics and endocytosis []. It serves as the targeting signal recognition factor for NPFX(1,2)D-mediated endocytosis [].Sla1p contains multiple domains including three SH3 domains, a SAM (sterile alpha motif) domain, and a Sla1 homology domain 1 (SHD1). This entry represents the first SH3 domain of Sla1.
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Protein Domain
IPR035821 | Sla1_SH3_3
Type: Domain
Description: Sla1 is a fungal protein involved in coupling the actin cytoskeleton to the endocytic machinery during endocytosis. It binds to Sla2 (yeast Huntingtin interacting protein-1 HIP1), which plays a role in regulating actin dynamics and endocytosis []. It serves as the targeting signal recognition factor for NPFX(1,2)D-mediated endocytosis [].Sla1p contains multiple domains including three SH3 domains, a SAM (sterile alpha motif) domain, and a Sla1 homology domain 1 (SHD1). This entry represents the third SH3 domain of Sla1.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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