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Search results 1 to 100 out of 241 for T

Category restricted to InteractionExperiment (x)

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Category: InteractionExperiment
Type Details Score
Interaction Experiment
Description: Cbl-b mediates TGF sensitivity by downregulating inhibitory SMAD7 in primary T cells.
Interaction Experiment
Description: Endothelin-1-dependent nuclear factor of activated T lymphocyte signaling associates with transcriptional coactivator p300 in the activation of the B cell leukemia-2 promoter in cardiac myocytes.
Interaction Experiment
Description: A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo.
Interaction Experiment
Description: Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1.
Interaction Experiment
Description: The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution.
Interaction Experiment
Description: p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers.
Interaction Experiment
Description: Identification of SWI.SNF complex subunit BAF60a as a determinant of the transactivation potential of Fos/Jun dimers.
Interaction Experiment
Description: RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling.
Interaction Experiment
Description: ZIP kinase, a novel serine/threonine kinase which mediates apoptosis.
Interaction Experiment
Description: Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.
Interaction Experiment
Description: BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation.
Interaction Experiment
Description: Dot far-western blot analysis of relative binding affinities of the Src homology 3 domains of Efs and its related proteins.
Interaction Experiment
Description: Identification of a novel kinesin-related protein, KRMP1, as a target for mitotic peptidyl-prolyl isomerase Pin1.
Interaction Experiment
Description: Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.
Interaction Experiment
Description: Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase.
Interaction Experiment
Description: Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit.
Interaction Experiment
Description: Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration.
Interaction Experiment
Description: p62 serves as a shuttling factor for TrkA interaction with the proteasome.
Interaction Experiment
Description: The xeroderma pigmentosum group E gene product DDB2 activates nucleotide excision repair by regulating the level of p21Waf1/Cip1.
Interaction Experiment
Description: Regulation of phosphoglucose isomerase/autocrine motility factor activities by the poly(ADP-ribose) polymerase family-14.
Interaction Experiment
Description: Interaction between GADD34 and kinesin superfamily, KIF3A.
Interaction Experiment
Description: A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition.
Interaction Experiment
Description: An atlas of combinatorial transcriptional regulation in mouse and man.
Interaction Experiment
Description: Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase.
Interaction Experiment
Description: Enhanced gene activation by Notch and BMP signaling cross-talk.
Interaction Experiment
Description: The H19 locus acts in vivo as a tumor suppressor.
Interaction Experiment
Description: Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1.
Interaction Experiment
Description: The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.
Interaction Experiment
Description: Dynamic recruitment of axin by Dishevelled protein assemblies.
Interaction Experiment
Description: BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression.
Interaction Experiment
Description: In vivo dual-tagging proteomic approach in studying signaling pathways in immune response.
Interaction Experiment
Description: Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells.
Interaction Experiment
Description: Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A.
Interaction Experiment
Description: Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor.
Interaction Experiment
Description: Homeobox protein MSX2 acts as a molecular defense mechanism for preventing ossification in ligament fibroblasts.
Interaction Experiment
Description: Oncogenic activation of c-Myb correlates with a loss of negative regulation by TIF1beta and Ski.
Interaction Experiment
Description: The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families.
Interaction Experiment
Description: CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses.
Interaction Experiment
Description: Polyubiquitylation of PARP-1 through ubiquitin K48 is modulated by activated DNA, NAD+, and dipeptides.
Interaction Experiment
Description: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid beta-protein.
Interaction Experiment
Description: Constitutive expression of the brg1 gene requires GC-boxes near to the transcriptional start site.
Interaction Experiment
Description: Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13).
Interaction Experiment
Description: ER-stress-inducible Herp, facilitates the degradation of immature nicastrin.
Interaction Experiment
Description: Antiviral protein Viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells.
Interaction Experiment
Description: Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1.
Interaction Experiment
Description: The 19S proteasomal lid subunit POH1 enhances the transcriptional activation by Mitf in osteoclasts.
Interaction Experiment
Description: CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.
Interaction Experiment
Description: TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor.
Interaction Experiment
Description: Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain.
Interaction Experiment
Description: Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription.
Interaction Experiment
Description: Molecular Basis for the Anchoring of Proto-Oncoprotein Nup98 to the Cytoplasmic Face of the Nuclear Pore Complex.
Interaction Experiment
Description: Ptf1a and RBP-J cooperate in activating Pdx1 gene expression through binding to Area III.
Interaction Experiment
Description: Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice.
Interaction Experiment
Description: Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis.
Interaction Experiment
Description: The TSG101 protein binds to connexins and is involved in connexin degradation.
Interaction Experiment
Description: Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling.
Interaction Experiment
Description: Src kinase activity is essential for osteoclast function.
Interaction Experiment
Description: A reduction of licensed origins reveals strain-specific replication dynamics in mice.
Interaction Experiment
Description: The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways.
Interaction Experiment
Description: B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster.
Interaction Experiment
Description: Mammalian Cdh1/Fzr mediates its own degradation.
Interaction Experiment
Description: Biotin-ubiquitin tagging of mammalian proteins in Escherichia coli.
Interaction Experiment
Description: Aberrant molecular properties shared by familial Parkinsons disease-associated mutant UCH-L1 and carbonyl-modified UCH-L1.
Interaction Experiment
Description: CIS1, a cytokine-inducible SH2 protein, suppresses BCR/ABL-mediated transformation. Involvement of the ubiquitin proteasome pathway.
Interaction Experiment
Description: Aberrant interaction between Parkinson disease-associated mutant UCH-L1 and the lysosomal receptor for chaperone-mediated autophagy.
Interaction Experiment
Description: CIN85 interacting proteins in B cells-specific role for SHIP-1.
Interaction Experiment
Description: High-level expression and purification of recombinant SCF ubiquitin ligases.
Interaction Experiment
Description: The subunit 1 of the COP9 signalosome suppresses gene expression through its N-terminal domain and incorporates into the complex through the PCI domain.
Interaction Experiment
Description: The Mdm2 oncoprotein interacts with the cell fate regulator Numb.
Interaction Experiment
Description: The Rho GTPase effector protein, mDia, inhibits the DNA binding ability of the transcription factor Pax6 and changes the pattern of neurite extension in cerebellar granule cells through its binding to Pax6.
Interaction Experiment
Description: Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation.
Interaction Experiment
Description: Endotoxin conditioning induces VCP/p97-mediated and inducible nitric-oxide synthase-dependent Tyr284 nitration in protein phosphatase 2A.
Interaction Experiment
Description: hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria.
Interaction Experiment
Description: Lrp6 hypomorphic mutation affects bone mass through bone resorption in mice and impairs interaction with Mesd.
Interaction Experiment
Description: Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis.
Interaction Experiment
Description: Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product.
Interaction Experiment
Description: The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice.
Interaction Experiment
Description: Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone.
Interaction Experiment
Description: Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling.
Interaction Experiment
Description: Ca2(+)-dependent interaction of N-copine, a member of the two C2 domain protein family, with OS-9, the product of a gene frequently amplified in osteosarcoma.
Interaction Experiment
Description: Molecular cloning and characterization of CRLM-2, a novel type I cytokine receptor preferentially expressed in hematopoietic cells.
Interaction Experiment
Description: Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells.
Interaction Experiment
Description: Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex.
Interaction Experiment
Description: p53 phosphorylation and association with murine double minute 2, c-Jun NH2-terminal kinase, p14ARF, and p300/CBP during the cell cycle and after exposure to ultraviolet irradiation.
Interaction Experiment
Description: beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport.
Interaction Experiment
Description: FMIP, a novel Fms-interacting protein, affects granulocyte/macrophage differentiation.
Interaction Experiment
Description: The myristoylated alanine-rich C-kinase substrate (MARCKS) is sequentially phosphorylated by conventional, novel and atypical isotypes of protein kinase C.
Interaction Experiment
Description: VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
Interaction Experiment
Description: The second-largest subunit of the mouse DNA polymerase alpha-primase complex facilitates both production and nuclear translocation of the catalytic subunit of DNA polymerase alpha.
Interaction Experiment
Description: MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.
Interaction Experiment
Description: TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation.
Interaction Experiment
Description: Polyubiquitination of the neurotrophin receptor p75 directs neuronal cell survival.
Interaction Experiment
Description: p115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation.
Interaction Experiment
Description: Identification and characterization of a novel Delphilin variant with an alternative N-terminus.
Interaction Experiment
Description: Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport.
Interaction Experiment
Description: 14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitination and cytoplasmic body formation.
Interaction Experiment
Description: Rosbin: a novel homeobox-like protein gene expressed exclusively in round spermatids.
Interaction Experiment
Description: Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis.
Interaction Experiment
Description: a4, a unique kidney-specific isoform of mouse vacuolar H+-ATPase subunit a.
Interaction Experiment
Description: Helt, a novel basic-helix-loop-helix transcriptional repressor expressed in the developing central nervous system.