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Search results 101 to 200 out of 210 for Pip

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Type Details Score
GXD Expression      
Probe: MGI:3834708
Assay Type: RT-PCR
Annotation Date: 2009-03-09
Strength: Absent
Sex: Male
Emaps: EMAPS:3614125
Stage: TS25
Assay Id: MGI:3834863
Age: embryonic day 17.5
Specimen Label: E18
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3834708
Assay Type: RT-PCR
Annotation Date: 2009-03-09
Strength: Absent
Sex: Male
Emaps: EMAPS:3614127
Stage: TS27
Assay Id: MGI:3834863
Age: postnatal day 1
Specimen Label: 1d
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3834708
Assay Type: RT-PCR
Annotation Date: 2009-03-09
Strength: Absent
Sex: Male
Emaps: EMAPS:3614125
Stage: TS25
Assay Id: MGI:3834869
Age: embryonic day 17.5
Specimen Label: E18
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3834708
Assay Type: RT-PCR
Annotation Date: 2009-03-09
Strength: Absent
Sex: Male
Emaps: EMAPS:3614127
Stage: TS27
Assay Id: MGI:3834869
Age: postnatal day 1
Specimen Label: 1d
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3834708
Assay Type: RT-PCR
Annotation Date: 2009-03-09
Strength: Absent
Sex: Male
Emaps: EMAPS:3614127
Stage: TS27
Assay Id: MGI:3834868
Age: postnatal day 3
Specimen Label: 3d
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3834707
Assay Type: RNA in situ
Annotation Date: 2009-03-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1881225
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:3834720
Age: embryonic day 17.5
Note: Expression is present in the proacinar cells but not in the ductal cells.
Specimen Label: 3C
Detected: true
Specimen Num: 1
Publication
First Author: Windass JD
Year: 1984
Journal: Nucleic Acids Res
Title: Molecular cloning of cDNAs from androgen-independent mRNA species of DBA/2 mouse sub-maxillary glands.
Volume: 12
Issue: 3
Pages: 1361-76
Publication
First Author: Maruyama EO
Year: 2016
Journal: PLoS One
Title: Cell-Specific Cre Strains For Genetic Manipulation in Salivary Glands.
Volume: 11
Issue: 1
Pages: e0146711
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
SO Term
Author
Publication
First Author: Bortoff KD
Year: 1997
Journal: Endocrine
Title: Insulin induction of pip 92, CL-6, and novel mRNAs in rat hepatoma cells.
Volume: 7
Issue: 2
Pages: 199-207
Publication
First Author: Sun M
Year: 2020
Journal: FASEB J
Title: Control of Rab7a activity and localization through endosomal type Igamma PIP 5-kinase is required for endosome maturation and lysosome function.
Volume: 34
Issue: 2
Pages: 2730-2748
Allele
Name: prolactin induced protein; targeted mutation 1.1, Catherine E Ovitt
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Allele
Name: prolactin induced protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Publication
First Author: Lokuta MA
Year: 2007
Journal: Mol Biol Cell
Title: Type Igamma PIP kinase is a novel uropod component that regulates rear retraction during neutrophil chemotaxis.
Volume: 18
Issue: 12
Pages: 5069-80
GO Term
GO Term
GO Term
GO Term
Protein
Organism: Mus musculus/domesticus
Length: 450  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
GO Term
Protein
Organism: Mus musculus/domesticus
Length: 2097  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 497  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2052  
Fragment?: false
Publication    
First Author: Sekiya M
Year: 2023
Journal: Cell Rep
Title: Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function.
Pages: 112914
Protein Domain
Type: Family
Description: This entry represents archaeal Nre proteins. While most archaeal organisms encode only a single Nre protein, some encode two, NreA and NreB.NreA is an archaeal PCNA interacting protein that works together with the UvrABC proteins in repairing DNA damage resulting from exposure to DNA damaging agent MMC. NreA contains a putative PIP motif at its C terminus that is important for its function [].
Protein
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
Protein Domain
Type: Domain
Description: This conserved region is found in the N-terminal region of archaeal Nre proteins. While most archaeal organisms encode only a single Nre protein, some encode two, NreA and NreB. NreA is an archaeal PCNA interacting protein that works together with the UvrABC proteins in repairing DNA damage resulting from exposure to DNA damaging agent MMC. NreA contains a putative PIP motif at its C terminus that is important for its function [].
Protein Domain
Type: Domain
Description: This conserved region is found in the C-terminal region of archaeal Nre proteins. While most archaeal organisms encode only a single Nre protein, some encode two, NreA and NreB. NreA is an archaeal PCNA interacting protein that works together with the UvrABC proteins in repairing DNA damage resulting from exposure to DNA damaging agent MMC. NreA contains a putative PIP motif atits C terminus that is important for its function [].
Protein Domain
Type: Family
Description: Myotubularin-related protein 14 (MTMR14, also known as Jumpy) belongs to the myotubularin family, whose members are dual-specificity phosphatases that act primarily to dephosphorylate phosphoinositides (PIs). They act specifically on PI3P and PI3,5P2, dephosphorylating them to form PIP and PI5P, respectively []. MTMR14 interacts with early autophagosomes and negatively regulates progression through the steps of autophagy []. It has been linked to the a congenital muscle disorder known as myopathy, centronuclear, 1 (CNM1) [].
Publication
First Author: Giroux X
Year: 2016
Journal: Mol Microbiol
Title: A novel archaeal DNA repair factor that acts with the UvrABC system to repair mitomycin C-induced DNA damage in a PCNA-dependent manner.
Volume: 99
Issue: 1
Pages: 1-14
Protein Domain
Type: Domain
Description: Myotubularin-related protein 14 (MTMR14, also known as Jumpy) belongs to the myotubularin family, whose members are dual-specificity phosphatases that act primarily to dephosphorylate phosphoinositides (PIs). They act specifically on PI3P and PI3,5P2, dephosphorylating them to form PIP and PI5P, respectively []. MTMR14 interacts with early autophagosomes and negatively regulates progression through the steps of autophagy []. It has been linked to the a congenital muscle disorder known as myopathy, centronuclear, 1 (CNM1) [].MTMR14 contain a N-terminal PH-GRAM domain, a Rac-induced recruitment domain (RID) domain, an active PTP domain, a SET-interaction domain (SID), a coiled-coil region, and a C-terminal PDZ domain. This entry represents the PH-GRAM domain that binds to phosphoinositide lipid [].
Publication
First Author: Tosch V
Year: 2006
Journal: Hum Mol Genet
Title: A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy.
Volume: 15
Issue: 21
Pages: 3098-106
Publication
First Author: Vergne I
Year: 2009
Journal: EMBO J
Title: Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy.
Volume: 28
Issue: 15
Pages: 2244-58
Publication
First Author: Brown AL
Year: 1999
Journal: Hum Mol Genet
Title: Bex1, a gene with increased expression in parthenogenetic embryos, is a member of a novel gene family on the mouse X chromosome.
Volume: 8
Issue: 4
Pages: 611-9
Publication
First Author: Pearsall GB
Year: 1997
Journal: Dev Neurosci
Title: Jimpy-4J mouse has a missense mutation in exon 2 of the Plp gene.
Volume: 19
Issue: 4
Pages: 337-41
Publication  
First Author: Yang CC
Year: 2016
Journal: Nat Commun
Title: Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells.
Volume: 7
Pages: 12135
Publication
First Author: Legate KR
Year: 2011
Journal: EMBO J
Title: Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2 synthesis.
Volume: 30
Issue: 22
Pages: 4539-53
Publication
First Author: Liu Y
Year: 2008
Journal: Mol Biol Cell
Title: The Sac1 phosphoinositide phosphatase regulates Golgi membrane morphology and mitotic spindle organization in mammals.
Volume: 19
Issue: 7
Pages: 3080-96
Publication
First Author: Badger CC
Year: 1990
Journal: Int J Rad Appl Instrum B
Title: Biodistribution of p-iodobenzoyl (PIP) labeled antibodies in a murine lymphoma model.
Volume: 17
Issue: 4
Pages: 381-7
Protein
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: true
Publication
First Author: Zhang X
Year: 2018
Journal: Cell Res
Title: Structure of the human activated spliceosome in three conformational states.
Volume: 28
Issue: 3
Pages: 307-322
Protein Domain
Type: Domain
Description: The mature U2 snRNP (small nuclear ribonucleoprotein particle) relies on the spliceosome assembly for its function, which involves the Splicing factor 3a (SF3a), an evolutionary eukaryotic conserved heterotrimeric complex, essential for pre-mRNA splicing []. This complex includes three subunits: SF3a60, SF3a66 and SF3a120 in the human complex, being Prp9, Prp11 and Prp21 the counterparts in Saccharomyces cerevisiae. SF3a60 possess a highly conserved C2H2-type zinc-finger domain at the C-terminal, while Prp9 has two such domains; SF3a66 and Prp11 contain one C2H2-type zinc-finger domain and SF3a120/Prp21 has two suppressor-of-white-apricot and prp21/spp91 (SURP) domains, followed by a short segment of charged residues. The SURP2 domain of SF3a120/Prp21 has a role in SF3a60/Prp9 binding, however, SURP1 domain function is unknown. The yeast structure shows that Prp9 interacts with Prp21 via a bidentate-binding mode, and Prp21 is wrapped around Prp11 [].This entry represents the C-terminal region of SF3a60 subunit (also known as SF3a3 and Spliceosome-associated protein 61 or Prp9 from yeast) from SF3a complex, found in eukaryotes. This domain has two conserved sequence motifs: PIP and CEICG. It contains a zinc-finger domain of the C2H2-type which might be important for RNA binding and protein-protein interactions with components of the SF3b complex [].
Publication
First Author: Rampazzo C
Year: 2002
Journal: Gene
Title: Mouse cytosolic and mitochondrial deoxyribonucleotidases: cDNA cloning of the mitochondrial enzyme, gene structures, chromosomal mapping and comparison with the human orthologs.
Volume: 294
Issue: 1-2
Pages: 109-17
Publication
First Author: Korrodi-Gregório L
Year: 2013
Journal: Biol Open
Title: TCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network.
Volume: 2
Issue: 5
Pages: 453-65
Publication
First Author: Eisenbeis CF
Year: 1995
Journal: Genes Dev
Title: Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator.
Volume: 9
Issue: 11
Pages: 1377-87
Publication
First Author: Yeung YG
Year: 1998
Journal: J Biol Chem
Title: A novel macrophage actin-associated protein (MAYP) is tyrosine-phosphorylated following colony stimulating factor-1 stimulation.
Volume: 273
Issue: 46
Pages: 30638-42
Publication
First Author: Sabha N
Year: 2016
Journal: J Clin Invest
Title: PIK3C2B inhibition improves function and prolongs survival in myotubular myopathy animal models.
Volume: 126
Issue: 9
Pages: 3613-25
Publication
First Author: Yoshikawa S
Year: 2005
Journal: J Appl Physiol (1985)
Title: Clara cell secretory protein and phospholipase A2 activity modulate acute ventilator-induced lung injury in mice.
Volume: 98
Issue: 4
Pages: 1264-71
Publication
First Author: Hamanaka K
Year: 2007
Journal: Am J Physiol Lung Cell Mol Physiol
Title: TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs.
Volume: 293
Issue: 4
Pages: L923-32
Publication
First Author: Hamanaka K
Year: 2010
Journal: Am J Physiol Lung Cell Mol Physiol
Title: TRPV4 channels augment macrophage activation and ventilator-induced lung injury.
Volume: 299
Issue: 3
Pages: L353-62
Publication
First Author: Li Q
Year: 1999
Journal: J Pharmacol Exp Ther
Title: Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice.
Volume: 291
Issue: 3
Pages: 999-1007
Publication
First Author: Murphy LC
Year: 1987
Journal: Cancer Res
Title: Expression of the gene encoding a prolactin-inducible protein by human breast cancers in vivo: correlation with steroid receptor status.
Volume: 47
Issue: 15
Pages: 4160-4
Publication
First Author: Inloes JM
Year: 2018
Journal: Biochemistry
Title: The Spastic Paraplegia-Associated Phospholipase DDHD1 Is a Primary Brain Phosphatidylinositol Lipase.
Volume: 57
Issue: 39
Pages: 5759-5767
Publication  
First Author: Tran DM
Year: 2023
Journal: Dis Model Mech
Title: Attenuated cerebellar phenotypes in Inpp4a truncation mutants with preserved phosphatase activity.
Volume: 16
Issue: 7
Publication
First Author: Mustacich DJ
Year: 1998
Journal: Arch Biochem Biophys
Title: Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice.
Volume: 350
Issue: 2
Pages: 183-92
Publication
First Author: Abu Jawdeh BG
Year: 2011
Journal: J Biol Chem
Title: Phosphoinositide binding differentially regulates NHE1 Na+/H+ exchanger-dependent proximal tubule cell survival.
Volume: 286
Issue: 49
Pages: 42435-42445
Publication
First Author: Houston IB
Year: 2007
Journal: Exp Hematol
Title: PU.1 immortalizes hematopoietic progenitors in a GM-CSF-dependent manner.
Volume: 35
Issue: 3
Pages: 374-384
Publication
First Author: Carlsson R
Year: 2003
Journal: Mol Immunol
Title: SPI-C, a PU-box binding ETS protein expressed temporarily during B-cell development and in macrophages, contains an acidic transactivation domain located to the N-terminus.
Volume: 39
Issue: 16
Pages: 1035-43
Publication
First Author: Mirels L
Year: 1998
Journal: J Histochem Cytochem
Title: Expression of gross cystic disease fluid protein-15/Prolactin-inducible protein in rat salivary glands.
Volume: 46
Issue: 9
Pages: 1061-71
Publication
First Author: Rolef Ben-Shahar T
Year: 2009
Journal: Mol Cell Biol
Title: Two fundamentally distinct PCNA interaction peptides contribute to chromatin assembly factor 1 function.
Volume: 29
Issue: 24
Pages: 6353-65
Publication
First Author: Dai G
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Osmoregulatory inositol transporter SMIT1 modulates electrical activity by adjusting PI(4,5)P2 levels.
Volume: 113
Issue: 23
Pages: E3290-9
Publication
First Author: Clarke JH
Year: 2009
Journal: J Comp Neurol
Title: Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brain.
Volume: 517
Issue: 3
Pages: 296-312
Protein
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: true
Publication
First Author: Khvotchev M
Year: 1998
Journal: J Biol Chem
Title: Developmentally regulated alternative splicing in a novel synaptojanin.
Volume: 273
Issue: 4
Pages: 2306-11
Publication
First Author: Reifler A
Year: 2013
Journal: Skelet Muscle
Title: Murine Fig4 is dispensable for muscle development but required for muscle function.
Volume: 3
Issue: 1
Pages: 21
Publication
First Author: Li R
Year: 2022
Journal: Autophagy
Title: Piperine promotes autophagy flux by P2RX4 activation in SNCA/α-synuclein-induced Parkinson disease model.
Volume: 18
Issue: 3
Pages: 559-575