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Search results 401 to 500 out of 519 for Tfam

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Type Details Score
Publication
17609113 | J:123923
First Author: Zhou Q
Year: 2007
Journal: Dev Cell
Title: A multipotent progenitor domain guides pancreatic organogenesis.
Volume: 13
Issue: 1
Pages: 103-14
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
20932939 | J:168654
First Author: Chung YC
Year: 2011
Journal: Gene Expr Patterns
Title: Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Volume: 11
Issue: 1-2
Pages: 84-92
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:345476
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
19656489 | J:151308
First Author: Gauthier BR
Year: 2009
Journal: Cell Metab
Title: PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression.
Volume: 10
Issue: 2
Pages: 110-8
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Publication
31088855 | J:277520
First Author: Koh JH
Year: 2019
Journal: Diabetes
Title: TFAM Enhances Fat Oxidation and Attenuates High-Fat Diet-Induced Insulin Resistance in Skeletal Muscle.
Volume: 68
Issue: 8
Pages: 1552-1564
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Publication
36046191 | J:327998
First Author: Fujii M
Year: 2022
Journal: iScience
Title: TFAM expression in brown adipocytes confers obesity resistance by secreting extracellular vesicles that promote self-activation.
Volume: 25
Issue: 9
Pages: 104889
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Publication
36674978 | J:336240
 
First Author: Sierra-Magro A
Year: 2023
Journal: Int J Mol Sci
Title: C/EBPβ Regulates TFAM Expression, Mitochondrial Function and Autophagy in Cellular Models of Parkinson's Disease.
Volume: 24
Issue: 2
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Publication
25822152 | J:229260
First Author: Ikeda M
Year: 2015
Journal: PLoS One
Title: Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress.
Volume: 10
Issue: 3
Pages: e0119687
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Publication
20816751 | J:165855
First Author: Nishiyama S
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Over-expression of Tfam improves the mitochondrial disease phenotypes in a mouse model system.
Volume: 401
Issue: 1
Pages: 26-31
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HT Experiment
GSE196628 | Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
32342250 | J:308515
First Author: Key J
Year: 2020
Journal: Neurogenetics
Title: Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease.
Volume: 21
Issue: 3
Pages: 187-203
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Allele
Tfam<tm1Smoc> | MGI:7292733
Name: transcription factor A, mitochondrial; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:6476445 | C57BL/6J-Tfam<tm1Smoc>/Smoc
Attribute String: coisogenic, targeted mutation, mutant strain
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HT Experiment
GSE203234 | Loss of Fatty Acid Degradation by Astrocytic Mitochondria Triggers Neuroinflammation and Neurodegeneration
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Bicc1<jcpk-67Gso> | MGI:4821847
 
Name: BicC family RNA binding protein 1; juvenile congenital polycystic kidney disease 67 Generoso
Allele Type: Chemically induced (other)
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Genotype
Genotype
Symbol: Bicc1/Bicc1 T(2;10)67Gso/T(2;10)67Gso
Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso
Zygosity: cx
Has Mutant Allele: true
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HT Experiment
E-GEOD-83368 | POLRMT regulates the switch between replication-primer formation and gene expression of mammalian mtDNA
Series Id: GSE83368
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
11944981 | J:75799
First Author: Chittenden L
Year: 2002
Journal: Genomics
Title: A new mouse model for autosomal recessive polycystic kidney disease.
Volume: 79
Issue: 4
Pages: 499-504
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Publication
12584442 | J:82437
First Author: Price SJ
Year: 2002
Journal: Cytogenet Genome Res
Title: Characterization of the region containing the jcpk PKD gene on mouse Chromosome 10.
Volume: 98
Issue: 1
Pages: 61-6
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Publication
23303943 | J:193910
First Author: Bormuth I
Year: 2013
Journal: J Neurosci
Title: Neuronal basic helix-loop-helix proteins Neurod2/6 regulate cortical commissure formation before midline interactions.
Volume: 33
Issue: 2
Pages: 641-51
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Publication
25548427 | -
 
First Author: Satoh J
Year: 2014
Journal: Dis Markers
Title: RNA-Seq data mining: downregulation of NeuroD6 serves as a possible biomarker for alzheimer's disease brains.
Volume: 2014
Pages: 123165
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Publication
26202100 | -
 
First Author: Li X
Year: 2015
Journal: Sci Rep
Title: Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer's disease.
Volume: 5
Pages: 12393
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Publication
22814253 | -
First Author: Baxter KK
Year: 2012
Journal: Exp Cell Res
Title: The neurogenic basic helix-loop-helix transcription factor NeuroD6 enhances mitochondrial biogenesis and bioenergetics to confer tolerance of neuronal PC12-NeuroD6 cells to the mitochondrial stressor rotenone.
Volume: 318
Issue: 17
Pages: 2200-14
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Protein Domain
IPR032650 | Neurod6
Type: Family
Description: Neurogenic differentiation factor 6 (Neurod6) is a basic helix-loop-helix (bHLH) transcription factor involved in the development and maintenance of the nervous system. It regulates cortical commissure formation before midline interactions during corpus callosum development []. Neurod6 possesses mitochondrial biogenic properties by amplifying the mitochondrial DNA content and TFAM expression levels, a key regulator for mitochondrial biogenesis []. Downregulation of NeuroD6 has been linked to Alzheimer's disease [, ].The bHLH (basic Helix-Loop-Helix) proteins contain the bHLH domain that is approximately 60 amino acids long and consists of a DNA-binding basic region followed by two a-helices separated by a variable loop region (HLH). The HLH domain promotes dimerisation, allowing the formation of homo- or heterodimeric complexes between different family members. Many bHLH proteins have been shown to act as transcriptional regulators [].
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Publication
34838815 | J:322461
 
First Author: Li T
Year: 2022
Journal: Neuropharmacology
Title: Mitochondriomics reveals the underlying neuroprotective mechanism of TrkB receptor agonist R13 in the 5×FAD mice.
Volume: 204
Pages: 108899
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Publication
23147249 | J:198840
First Author: Seibenhener ML
Year: 2013
Journal: Biochim Biophys Acta
Title: A role for sequestosome 1/p62 in mitochondrial dynamics, import and genome integrity.
Volume: 1833
Issue: 3
Pages: 452-9
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Publication
31474566 | J:283642
First Author: Chung KW
Year: 2019
Journal: Cell Metab
Title: Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis.
Volume: 30
Issue: 4
Pages: 784-799.e5
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Publication
34583974 | J:318647
 
First Author: Kuwabara T
Year: 2021
Journal: Life Sci Alliance
Title: SATB1-dependent mitochondrial ROS production controls TCR signaling in CD4 T cells.
Volume: 4
Issue: 11
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Publication
32373606 | J:311088
 
First Author: Yang L
Year: 2020
Journal: Front Cell Dev Biol
Title: OPA1-Exon4b Binds to mtDNA D-Loop for Transcriptional and Metabolic Modulation, Independent of Mitochondrial Fusion.
Volume: 8
Pages: 180
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Publication
19366608 | J:149222
First Author: Pellegrini M
Year: 2009
Journal: Biochim Biophys Acta
Title: MTERF2 is a nucleoid component in mammalian mitochondria.
Volume: 1787
Issue: 5
Pages: 296-302
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Publication
30899058 | J:276671
First Author: Kumar P
Year: 2019
Journal: Sci Rep
Title: IL-27 promotes NK cell effector functions via Maf-Nrf2 pathway during influenza infection.
Volume: 9
Issue: 1
Pages: 4984
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Publication
27897204 | J:287498
 
First Author: Oka S
Year: 2016
Journal: Sci Rep
Title: Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease.
Volume: 6
Pages: 37889
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Publication
32084533 | J:311344
 
First Author: Singulani MP
Year: 2020
Journal: Exp Gerontol
Title: Impairment of PGC-1α-mediated mitochondrial biogenesis precedes mitochondrial dysfunction and Alzheimer's pathology in the 3xTg mouse model of Alzheimer's disease.
Volume: 133
Pages: 110882
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Publication
20413656 | J:160706
First Author: Ylikallio E
Year: 2010
Journal: Hum Mol Genet
Title: High mitochondrial DNA copy number has detrimental effects in mice.
Volume: 19
Issue: 13
Pages: 2695-705
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Publication
31803904 | J:282801
First Author: Salerno AG
Year: 2019
Journal: Biochem J
Title: Lack of mitochondrial NADP(H)-transhydrogenase expression in macrophages exacerbates atherosclerosis in hypercholesterolemic mice.
Volume: 476
Issue: 24
Pages: 3769-3789
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Publication
25670793 | J:238889
First Author: Wu LL
Year: 2015
Journal: Development
Title: Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors.
Volume: 142
Issue: 4
Pages: 681-91
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Publication
17179207 | J:117460
First Author: Suliman HB
Year: 2007
Journal: J Cell Sci
Title: A new activating role for CO in cardiac mitochondrial biogenesis.
Volume: 120
Issue: Pt 2
Pages: 299-308
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Publication
24381004 | J:211616
First Author: Vettor R
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Exercise training boosts eNOS-dependent mitochondrial biogenesis in mouse heart: role in adaptation of glucose metabolism.
Volume: 306
Issue: 5
Pages: E519-28
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Publication
15994412 | J:101197
First Author: Suliman HB
Year: 2005
Journal: FASEB J
Title: Toll-like receptor 4 mediates mitochondrial DNA damage and biogenic responses after heat-inactivated E. coli.
Volume: 19
Issue: 11
Pages: 1531-3
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Publication
35676242 | J:325564
First Author: Lian WS
Year: 2022
Journal: Cell Death Dis
Title: Histone H3K27 demethylase UTX compromises articular chondrocyte anabolism and aggravates osteoarthritic degeneration.
Volume: 13
Issue: 6
Pages: 538
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Publication
36691038 | J:344524
First Author: Wang B
Year: 2023
Journal: Cell Commun Signal
Title: The mitochondrial Ahi1/GR participates the regulation on mtDNA copy numbers and brain ATP levels and modulates depressive behaviors in mice.
Volume: 21
Issue: 1
Pages: 21
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Publication
24423644 | J:211609
 
First Author: Choi J
Year: 2014
Journal: Neurobiol Dis
Title: PGC-1α regulation of mitochondrial degeneration in experimental diabetic neuropathy.
Volume: 64
Pages: 118-30
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Publication
22675199 | J:188932
First Author: Julian MW
Year: 2012
Journal: J Immunol
Title: Mitochondrial transcription factor A serves as a danger signal by augmenting plasmacytoid dendritic cell responses to DNA.
Volume: 189
Issue: 1
Pages: 433-43
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Publication
25682918 | J:219869
 
First Author: Hering T
Year: 2015
Journal: Exp Neurol
Title: Selective striatal mtDNA depletion in end-stage Huntington's disease R6/2 mice.
Volume: 266
Pages: 22-9
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Publication
22589249 | J:185361
First Author: Chaturvedi RK
Year: 2012
Journal: Hum Mol Genet
Title: Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease.
Volume: 21
Issue: 15
Pages: 3474-88
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Publication
26908605 | J:233022
First Author: Yin X
Year: 2016
Journal: Hum Mol Genet
Title: Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease.
Volume: 25
Issue: 9
Pages: 1739-53
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Publication
27532055 | J:258184
First Author: Kühl I
Year: 2016
Journal: Sci Adv
Title: POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.
Volume: 2
Issue: 8
Pages: e1600963
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Publication
31026811 | J:289184
First Author: Yang W
Year: 2019
Journal: J Endocrinol
Title: Glucagon regulates hepatic mitochondrial function and biogenesis through FOXO1.
Volume: 241
Issue: 3
Pages: 265-278
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Publication
20501642 | J:162487
First Author: Ikeda Y
Year: 2010
Journal: Mol Endocrinol
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Year: 2010
Journal: Free Radic Biol Med
Title: Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice.
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Year: 2013
Journal: Physiol Genomics
Title: Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.
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Title: NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway.
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Title: Cilostazol attenuates murine hepatic ischemia and reperfusion injury via heme oxygenase-dependent activation of mitochondrial biogenesis.
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Title: Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice.
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