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Search results 101 to 200 out of 531 for Lyn

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Categories

Category: Publication
Type Details Score
Publication
First Author: Chew V
Year: 2007
Journal: J Biol Chem
Title: Leupaxin negatively regulates B cell receptor signaling.
Volume: 282
Issue: 37
Pages: 27181-91
Publication  
First Author: Luo L
Year: 2017
Journal: Nat Commun
Title: SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages.
Volume: 8
Pages: 14133
Publication
First Author: Rawlings DJ
Year: 1996
Journal: Science
Title: Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases.
Volume: 271
Issue: 5250
Pages: 822-5
Publication
First Author: Silver K
Year: 2006
Journal: Eur J Immunol
Title: Spontaneous class switching and B cell hyperactivity increase autoimmunity against intracellular self antigen in Lyn-deficient mice.
Volume: 36
Issue: 11
Pages: 2920-7
Publication      
First Author: Choi JH
Year: 2014
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Lemon. Updated on October 29, 2014
Publication
First Author: Miki S
Year: 2001
Journal: Genes Cells
Title: Reduction of atherosclerosis despite hypercholesterolemia in lyn-deficient mice fed a high-fat diet.
Volume: 6
Issue: 1
Pages: 37-42
Publication
First Author: Khan N
Year: 2021
Journal: J Immunol
Title: Signal Integration by Translocation and Phosphorylation of PKCδ in the B Cell Alternate Pathway.
Volume: 207
Issue: 9
Pages: 2288-2296
Publication
First Author: Umemori H
Year: 2003
Journal: Neuroscience
Title: Impairment of N-methyl-D-aspartate receptor-controlled motor activity in LYN-deficient mice.
Volume: 118
Issue: 3
Pages: 709-13
Publication
First Author: Lannutti BJ
Year: 2006
Journal: Oncogene
Title: Increased megakaryocytopoiesis in Lyn-deficient mice.
Volume: 25
Issue: 23
Pages: 3316-24
Publication
First Author: Sinha M
Year: 2016
Journal: Am J Respir Cell Mol Biol
Title: Immune Defense Protein Expression in Highly Purified Mouse Lung Epithelial Cells.
Volume: 54
Issue: 6
Pages: 802-13
Publication
First Author: Du C
Year: 2002
Journal: J Immunol
Title: Increased severity of experimental allergic encephalomyelitis in lyn-/- mice in the absence of elevated proinflammatory cytokine response in the central nervous system.
Volume: 168
Issue: 6
Pages: 3105-12
Publication
First Author: Oracki SA
Year: 2010
Journal: J Immunol
Title: CTLA4Ig alters the course of autoimmune disease development in Lyn-/- mice.
Volume: 184
Issue: 2
Pages: 757-63
Publication
First Author: Volkmann C
Year: 2016
Journal: EMBO J
Title: Molecular requirements of the B-cell antigen receptor for sensing monovalent antigens.
Volume: 35
Issue: 21
Pages: 2371-2381
Publication
First Author: Poderycki M
Year: 2010
Journal: J Immunol
Title: A minor catalytic activity of Src family kinases is sufficient for maximal activation of mast cells via the high-affinity IgE receptor.
Volume: 184
Issue: 1
Pages: 84-93
Publication
First Author: Hughan SC
Year: 2014
Journal: J Biol Chem
Title: Dok-2 adaptor protein regulates the shear-dependent adhesive function of platelet integrin αIIbβ3 in mice.
Volume: 289
Issue: 8
Pages: 5051-60
Publication
First Author: Pellefigues C
Year: 2018
Journal: Nat Commun
Title: Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs.
Volume: 9
Issue: 1
Pages: 725
Publication
First Author: Ferry H
Year: 2005
Journal: Eur J Immunol
Title: Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival.
Volume: 35
Issue: 12
Pages: 3655-63
Publication
First Author: Silver KL
Year: 2007
Journal: Eur J Immunol
Title: MyD88-dependent autoimmune disease in Lyn-deficient mice.
Volume: 37
Issue: 10
Pages: 2734-43
Publication  
First Author: Pellefigues C
Year: 2022
Journal: Front Immunol
Title: AMG853, A Bispecific Prostaglandin D2 Receptor 1 and 2 Antagonist, Dampens Basophil Activation and Related Lupus-Like Nephritis Activity in Lyn-Deficient Mice.
Volume: 13
Pages: 824686
Publication
First Author: Allman D
Year: 2001
Journal: J Immunol
Title: Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation.
Volume: 167
Issue: 12
Pages: 6834-40
Publication
First Author: Bull KR
Year: 2013
Journal: PLoS Genet
Title: Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations.
Volume: 9
Issue: 1
Pages: e1003219
Publication  
First Author: Gottschalk TA
Year: 2022
Journal: Front Immunol
Title: Loss of CD11b Accelerates Lupus Nephritis in Lyn-Deficient Mice Without Disrupting Glomerular Leukocyte Trafficking.
Volume: 13
Pages: 875359
Publication
First Author: Parameswaran N
Year: 2013
Journal: J Immunol
Title: Spatial coupling of JNK activation to the B cell antigen receptor by tyrosine-phosphorylated ezrin.
Volume: 190
Issue: 5
Pages: 2017-26
Publication      
First Author: Zeng M
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Pacific
Publication      
First Author: Wang KW
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Cress
Publication
First Author: Li W
Year: 2014
Journal: Circ Res
Title: Thymidine phosphorylase participates in platelet signaling and promotes thrombosis.
Volume: 115
Issue: 12
Pages: 997-1006
Publication
First Author: Scapini P
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice.
Volume: 108
Issue: 41
Pages: E823-32
Publication
First Author: Kawakami Y
Year: 2000
Journal: J Immunol
Title: Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation.
Volume: 165
Issue: 3
Pages: 1210-9
Publication
First Author: Takeshita H
Year: 1998
Journal: Int Immunol
Title: Abrogation of autoimmune disease in Lyn-deficient mice by the mutation of the Btk gene.
Volume: 10
Issue: 4
Pages: 435-44
Publication
First Author: Guo B
Year: 2013
Journal: Eur J Immunol
Title: A novel Lyn-protein kinase Cδ/ε-protein kinase D axis is activated in B cells by signalosome-independent alternate pathway BCR signaling.
Volume: 43
Issue: 6
Pages: 1643-50
Publication
First Author: Hasegawa M
Year: 2001
Journal: J Immunol
Title: A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice.
Volume: 167
Issue: 5
Pages: 2469-78
Publication
First Author: Tsantikos E
Year: 2010
Journal: J Immunol
Title: Autoimmune disease in Lyn-deficient mice is dependent on an inflammatory environment established by IL-6.
Volume: 184
Issue: 3
Pages: 1348-60
Publication
First Author: Charles N
Year: 2010
Journal: Nat Med
Title: Basophils and the T helper 2 environment can promote the development of lupus nephritis.
Volume: 16
Issue: 6
Pages: 701-7
Publication
First Author: Harder KW
Year: 2004
Journal: Blood
Title: Perturbed myelo/erythropoiesis in Lyn-deficient mice is similar to that in mice lacking the inhibitory phosphatases SHP-1 and SHIP-1.
Volume: 104
Issue: 13
Pages: 3901-10
Publication  
First Author: Nataraja C
Year: 2021
Journal: Front Immunol
Title: GILZ Regulates the Expression of Pro-Inflammatory Cytokines and Protects Against End-Organ Damage in a Model of Lupus.
Volume: 12
Pages: 652800
Publication
First Author: Hernandez-Hansen V
Year: 2004
Journal: J Immunol
Title: Dysregulated FcepsilonRI signaling and altered Fyn and SHIP activities in Lyn-deficient mast cells.
Volume: 173
Issue: 1
Pages: 100-12
Publication
First Author: Rovedo M
Year: 2008
Journal: J Virol
Title: Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase Lyn.
Volume: 82
Issue: 17
Pages: 8520-8
Publication
First Author: Gross AJ
Year: 2011
Journal: Eur J Immunol
Title: Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells.
Volume: 41
Issue: 12
Pages: 3645-55
Publication
First Author: Moon BG
Year: 2004
Journal: Cell Immunol
Title: Abrogation of autoimmune disease in Lyn-deficient mice by the deletion of IL-5 receptor alpha chain gene.
Volume: 228
Issue: 2
Pages: 110-8
Publication
First Author: Lovewell RR
Year: 2014
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Pseudomonas aeruginosa flagellar motility activates the phagocyte PI3K/Akt pathway to induce phagocytic engulfment.
Volume: 306
Issue: 7
Pages: L698-707
Publication
First Author: Kawakami Y
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Regulation of protein kinase CbetaI by two protein-tyrosine kinases, Btk and Syk.
Volume: 97
Issue: 13
Pages: 7423-8
Publication
First Author: Gomez G
Year: 2005
Journal: J Immunol
Title: Impaired FcepsilonRI-dependent gene expression and defective eicosanoid and cytokine production as a consequence of Fyn deficiency in mast cells.
Volume: 175
Issue: 11
Pages: 7602-10
Publication
First Author: Whyburn LR
Year: 2003
Journal: J Immunol
Title: Reduced dosage of Bruton's tyrosine kinase uncouples B cell hyperresponsiveness from autoimmunity in lyn-/- mice.
Volume: 171
Issue: 4
Pages: 1850-8
Publication
First Author: Parravicini V
Year: 2002
Journal: Nat Immunol
Title: Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation.
Volume: 3
Issue: 8
Pages: 741-8
Publication
First Author: Cai H
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Differential transformation capacity of Src family kinases during the initiation of prostate cancer.
Volume: 108
Issue: 16
Pages: 6579-84
Publication
First Author: Brian BF 4th
Year: 2022
Journal: Sci Adv
Title: A dominant function of LynB kinase in preventing autoimmunity.
Volume: 8
Issue: 16
Pages: eabj5227
Publication
First Author: Pore D
Year: 2018
Journal: J Immunol
Title: Cutting Edge: Deletion of Ezrin in B Cells of Lyn-Deficient Mice Downregulates Lupus Pathology.
Volume: 201
Issue: 5
Pages: 1353-1358
Publication
First Author: Cornall RJ
Year: 1998
Journal: Immunity
Title: Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection.
Volume: 8
Issue: 4
Pages: 497-508
Publication
First Author: Shih TA
Year: 2002
Journal: Nat Immunol
Title: Role of antigen receptor affinity in T cell-independent antibody responses in vivo.
Volume: 3
Issue: 4
Pages: 399-406
Publication
First Author: Xiao W
Year: 2010
Journal: Blood
Title: Lyn- and PLC-beta3-dependent regulation of SHP-1 phosphorylation controls Stat5 activity and myelomonocytic leukemia-like disease.
Volume: 116
Issue: 26
Pages: 6003-13
Publication
First Author: Xiao W
Year: 2011
Journal: Immunity
Title: Phospholipase C-β3 regulates FcɛRI-mediated mast cell activation by recruiting the protein phosphatase SHP-1.
Volume: 34
Issue: 6
Pages: 893-904
Publication
First Author: Kim HJ
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo.
Volume: 106
Issue: 7
Pages: 2325-30
Publication
First Author: Contreras CM
Year: 2007
Journal: Mol Immunol
Title: Btk regulates multiple stages in the development and survival of B-1 cells.
Volume: 44
Issue: 10
Pages: 2719-28
Publication    
First Author: Freedman TS
Year: 2015
Journal: Elife
Title: LynA regulates an inflammation-sensitive signaling checkpoint in macrophages.
Volume: 4
Publication
First Author: Zhang K
Year: 2011
Journal: Cancer Res
Title: CD8+ T cells regulate bone tumor burden independent of osteoclast resorption.
Volume: 71
Issue: 14
Pages: 4799-808
Publication
First Author: Zhu Z
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling.
Volume: 110
Issue: 14
Pages: E1282-90
Publication
First Author: Canobbio I
Year: 2015
Journal: Biochem J
Title: The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets.
Volume: 469
Issue: 2
Pages: 199-210
Publication
First Author: Hibbs ML
Year: 1997
Journal: Int J Biochem Cell Biol
Title: Lyn, a src-like tyrosine kinase.
Volume: 29
Issue: 3
Pages: 397-400
Publication
First Author: Guo B
Year: 2013
Journal: J Immunol
Title: IL-4 upregulates Igα and Igβ protein, resulting in augmented IgM maturation and B cell receptor-triggered B cell activation.
Volume: 191
Issue: 2
Pages: 670-7
Publication
First Author: Majeed M
Year: 2001
Journal: J Leukoc Biol
Title: Role of Src kinases and Syk in Fcgamma receptor-mediated phagocytosis and phagosome-lysosome fusion.
Volume: 70
Issue: 5
Pages: 801-11
Publication
First Author: Yamashita Y
Year: 2007
Journal: J Immunol
Title: Cutting edge: genetic variation influences Fc epsilonRI-induced mast cell activation and allergic responses.
Volume: 179
Issue: 2
Pages: 740-3
Publication
First Author: Ahn E
Year: 2006
Journal: Blood
Title: LIME acts as a transmembrane adapter mediating BCR-dependent B-cell activation.
Volume: 107
Issue: 4
Pages: 1521-7
Publication
First Author: Krebs DL
Year: 2012
Journal: J Immunol
Title: Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells.
Volume: 188
Issue: 10
Pages: 5094-105
Publication
First Author: Kannan S
Year: 2009
Journal: PLoS One
Title: Alveolar epithelial type II cells activate alveolar macrophages and mitigate P. Aeruginosa infection.
Volume: 4
Issue: 3
Pages: e4891
Publication
First Author: Moore KJ
Year: 2002
Journal: J Biol Chem
Title: A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.
Volume: 277
Issue: 49
Pages: 47373-9
Publication
First Author: Hong H
Year: 2007
Journal: Blood
Title: The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn.
Volume: 110
Issue: 7
Pages: 2511-9
Publication
First Author: Gross AJ
Year: 2009
Journal: J Immunol
Title: Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance.
Volume: 182
Issue: 9
Pages: 5382-92
Publication
First Author: Orschell CM
Year: 2008
Journal: Exp Hematol
Title: Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells.
Volume: 36
Issue: 5
Pages: 655-66
Publication
First Author: Mermel CH
Year: 2006
Journal: Blood
Title: Src family kinases are important negative regulators of G-CSF-dependent granulopoiesis.
Volume: 108
Issue: 8
Pages: 2562-8
Publication
First Author: Iwaki S
Year: 2005
Journal: J Biol Chem
Title: Btk plays a crucial role in the amplification of Fc epsilonRI-mediated mast cell activation by kit.
Volume: 280
Issue: 48
Pages: 40261-70
Publication
First Author: Chari R
Year: 2009
Journal: Blood
Title: Lyn, PKC-delta, SHIP-1 interactions regulate GPVI-mediated platelet-dense granule secretion.
Volume: 114
Issue: 14
Pages: 3056-63
Publication
First Author: Fang MM
Year: 2018
Journal: J Immunol
Title: Oxidant Signaling Mediated by Nox2 in Neutrophils Promotes Regenerative Myelopoiesis and Tissue Recovery following Ischemic Damage.
Volume: 201
Issue: 8
Pages: 2414-2426
Publication
First Author: Meng F
Year: 1997
Journal: J Exp Med
Title: Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and Lyn.
Volume: 185
Issue: 9
Pages: 1661-70
Publication
First Author: Zikherman J
Year: 2013
Journal: J Immunol
Title: The structural wedge domain of the receptor-like tyrosine phosphatase CD45 enforces B cell tolerance by regulating substrate specificity.
Volume: 190
Issue: 6
Pages: 2527-35
Publication
First Author: Wang W
Year: 2016
Journal: Circ Res
Title: LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis.
Volume: 119
Issue: 6
Pages: e91-e103
Publication
First Author: Hernandez-Hansen V
Year: 2005
Journal: J Immunol
Title: Increased expression of genes linked to FcepsilonRI Signaling and to cytokine and chemokine production in Lyn-deficient mast cells.
Volume: 175
Issue: 12
Pages: 7880-8
Publication
First Author: Gelman IH
Year: 2014
Journal: Mol Cancer Res
Title: Differential requirement for Src family tyrosine kinases in the initiation, progression, and metastasis of prostate cancer.
Volume: 12
Issue: 10
Pages: 1470-9
Publication
First Author: Sobota A
Year: 2005
Journal: J Immunol
Title: Binding of IgG-opsonized particles to Fc gamma R is an active stage of phagocytosis that involves receptor clustering and phosphorylation.
Volume: 175
Issue: 7
Pages: 4450-7
Publication
First Author: Xiao W
Year: 2008
Journal: J Clin Invest
Title: Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5.
Volume: 118
Issue: 3
Pages: 924-34
Publication
First Author: Saijo K
Year: 2003
Journal: Nat Immunol
Title: Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development.
Volume: 4
Issue: 3
Pages: 274-9
Publication
First Author: Gu H
Year: 2003
Journal: J Cell Biol
Title: Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis.
Volume: 161
Issue: 6
Pages: 1151-61
Publication
First Author: Lee LJ
Year: 2005
Journal: J Neurosci
Title: NMDA receptor-dependent regulation of axonal and dendritic branching.
Volume: 25
Issue: 9
Pages: 2304-11
Publication
First Author: Peng C
Year: 2012
Journal: PLoS One
Title: LSK derived LSK- cells have a high apoptotic rate related to survival regulation of hematopoietic and leukemic stem cells.
Volume: 7
Issue: 6
Pages: e38614
Publication
First Author: Yu M
Year: 2006
Journal: J Immunol
Title: Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI.
Volume: 176
Issue: 4
Pages: 2421-9
Publication
First Author: Grewal PK
Year: 2006
Journal: Mol Cell Biol
Title: ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling.
Volume: 26
Issue: 13
Pages: 4970-81
Publication
First Author: Proekt I
Year: 2016
Journal: J Clin Invest
Title: LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity.
Volume: 126
Issue: 10
Pages: 3758-3771
Publication
First Author: Gutierrez T
Year: 2010
Journal: Eur J Immunol
Title: Separate checkpoints regulate splenic plasma cell accumulation and IgG autoantibody production in Lyn-deficient mice.
Volume: 40
Issue: 7
Pages: 1897-905
Publication
First Author: Nelson MP
Year: 2011
Journal: J Immunol
Title: IL-33 and M2a alveolar macrophages promote lung defense against the atypical fungal pathogen Pneumocystis murina.
Volume: 186
Issue: 4
Pages: 2372-81
Publication
First Author: Schram BR
Year: 2008
Journal: J Immunol
Title: B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements.
Volume: 180
Issue: 7
Pages: 4728-41
Publication
First Author: Samuels AL
Year: 2009
Journal: Blood
Title: Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation.
Volume: 113
Issue: 16
Pages: 3845-56
Publication
First Author: Nunomura S
Year: 2010
Journal: Eur J Immunol
Title: FcepsilonRI beta-chain ITAM amplifies PI3K-signaling to ensure synergistic degranulation response via FcepsilonRI and adenosine receptors.
Volume: 40
Issue: 4
Pages: 1205-17
Publication
First Author: Borneo J
Year: 2007
Journal: Exp Hematol
Title: Src family kinase-mediated negative regulation of hematopoietic stem cell mobilization involves both intrinsic and microenvironmental factors.
Volume: 35
Issue: 7
Pages: 1026-37
Publication  
First Author: Futosi K
Year: 2023
Journal: Front Pharmacol
Title: Analysis of intracellular tyrosine phosphorylation in circulating neutrophils as a rapid assay for the in vivo effect of oral tyrosine kinase inhibitors.
Volume: 14
Pages: 1056154
Publication
First Author: Fitzer-Attas CJ
Year: 2000
Journal: J Exp Med
Title: Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn.
Volume: 191
Issue: 4
Pages: 669-82
Publication
First Author: Lee JY
Year: 2005
Journal: Biochem Pharmacol
Title: The regulation of the expression of inducible nitric oxide synthase by Src-family tyrosine kinases mediated through MyD88-independent signaling pathways of Toll-like receptor 4.
Volume: 70
Issue: 8
Pages: 1231-40
Publication
First Author: Pereira S
Year: 2001
Journal: J Immunol
Title: Resting murine neutrophils express functional alpha 4 integrins that signal through Src family kinases.
Volume: 166
Issue: 6
Pages: 4115-23
Publication
First Author: Fujii Y
Year: 2003
Journal: FEBS Lett
Title: Targeting of MIST to Src-family kinases via SKAP55-SLAP-130 adaptor complex in mast cells.
Volume: 540
Issue: 1-3
Pages: 111-6
Publication
First Author: Chan VW
Year: 1998
Journal: J Exp Med
Title: The molecular mechanism of B cell activation by toll-like receptor protein RP-105.
Volume: 188
Issue: 1
Pages: 93-101
Publication
First Author: Guo B
Year: 2007
Journal: J Immunol
Title: Cutting Edge: B cell receptor (BCR) cross-talk: the IL-4-induced alternate pathway for BCR signaling operates in parallel with the classical pathway, is sensitive to Rottlerin, and depends on Lyn.
Volume: 178
Issue: 8
Pages: 4726-30
Publication
First Author: Gutierrez T
Year: 2013
Journal: Eur J Immunol
Title: IL-21 promotes the production of anti-DNA IgG but is dispensable for kidney damage in lyn-/- mice.
Volume: 43
Issue: 2
Pages: 382-93