Type |
Details |
Score |
Publication |
First Author: |
Feig JE |
Year: |
2011 |
Journal: |
Circulation |
Title: |
Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques. |
Volume: |
123 |
Issue: |
9 |
Pages: |
989-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2014 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Association between shear stress and platelet-derived transforming growth factor-β1 release and activation in animal models of aortic valve stenosis. |
Volume: |
34 |
Issue: |
9 |
Pages: |
1924-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rossignoli A |
Year: |
2017 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Poliovirus Receptor-Related 2: A Cholesterol-Responsive Gene Affecting Atherosclerosis Development by Modulating Leukocyte Migration. |
Volume: |
37 |
Issue: |
3 |
Pages: |
534-542 |
|
•
•
•
•
•
|
Publication |
First Author: |
López-Parra M |
Year: |
2008 |
Journal: |
J Lipid Res |
Title: |
Regulatory effects of arachidonate 5-lipoxygenase on hepatic microsomal TG transfer protein activity and VLDL-triglyceride and apoB secretion in obese mice. |
Volume: |
49 |
Issue: |
12 |
Pages: |
2513-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Knecht TP |
Year: |
1995 |
Journal: |
Adv Genet |
Title: |
The influence of molecular biology on our understanding of lipoprotein metabolism and the pathobiology of atherosclerosis. |
Volume: |
32 |
|
Pages: |
141-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nargis T |
Year: |
2023 |
Journal: |
Biochim Biophys Acta Mol Cell Biol Lipids |
Title: |
Characterization of lipoproteins in human placenta and fetal circulation as well as gestational changes in lipoprotein assembly and secretion in human and mouse placentas. |
Volume: |
1868 |
Issue: |
9 |
Pages: |
159357 |
|
•
•
•
•
•
|
Publication |
First Author: |
Contos JJ |
Year: |
2001 |
Journal: |
Gene |
Title: |
The mouse lp(A3)/Edg7 lysophosphatidic acid receptor gene: genomic structure, chromosomal localization, and expression pattern. |
Volume: |
267 |
Issue: |
2 |
Pages: |
243-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamagate A |
Year: |
2008 |
Journal: |
J Clin Invest |
Title: |
FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice. |
Volume: |
118 |
Issue: |
6 |
Pages: |
2347-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beccari T |
Year: |
2001 |
Journal: |
Biosci Rep |
Title: |
Mouse beta-mannosidase: cDNA cloning, expression, and chromosomal localization. |
Volume: |
21 |
Issue: |
3 |
Pages: |
315-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iqbal J |
Year: |
2010 |
Journal: |
J Lipid Res |
Title: |
An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption. |
Volume: |
51 |
Issue: |
7 |
Pages: |
1929-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Herlea-Pana O |
Year: |
2015 |
Journal: |
Cardiovasc Res |
Title: |
Chemokine receptors CXCR2 and CX3CR1 differentially regulate functional responses of bone-marrow endothelial progenitors during atherosclerotic plaque regression. |
Volume: |
106 |
Issue: |
2 |
Pages: |
324-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Teupser D |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Atherosclerosis quantitative trait loci are sex- and lineage-dependent in an intercross of C57BL/6 and FVB/N low-density lipoprotein receptor-/- mice. |
Volume: |
103 |
Issue: |
1 |
Pages: |
123-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scerbo D |
Year: |
2017 |
Journal: |
J Lipid Res |
Title: |
Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids. |
Volume: |
58 |
Issue: |
6 |
Pages: |
1132-1142 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Q |
Year: |
2016 |
Journal: |
Mol Cell Endocrinol |
Title: |
Activation of farnesoid X receptor promotes triglycerides lowering by suppressing phospholipase A2 G12B expression. |
Volume: |
436 |
|
Pages: |
93-101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Babeu JP |
Year: |
2009 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Hepatocyte nuclear factor 4alpha contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation. |
Volume: |
297 |
Issue: |
1 |
Pages: |
G124-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kobayashi K |
Year: |
2023 |
Journal: |
Life Sci Alliance |
Title: |
Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth. |
Volume: |
6 |
Issue: |
10 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lindegaard ML |
Year: |
2008 |
Journal: |
Metabolism |
Title: |
Maternal diabetes causes coordinated down-regulation of genes involved with lipid metabolism in the murine fetal heart. |
Volume: |
57 |
Issue: |
6 |
Pages: |
766-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamamoto S |
Year: |
2014 |
Journal: |
Dev Biol |
Title: |
Contribution of calumin to embryogenesis through participation in the endoplasmic reticulum-associated degradation activity. |
Volume: |
393 |
Issue: |
1 |
Pages: |
33-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Srivillibhuthur M |
Year: |
2018 |
Journal: |
Dev Biol |
Title: |
TFAM is required for maturation of the fetal and adult intestinal epithelium. |
Volume: |
439 |
Issue: |
2 |
Pages: |
92-101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van Dyck F |
Year: |
2007 |
Journal: |
Cell Metab |
Title: |
Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons. |
Volume: |
6 |
Issue: |
5 |
Pages: |
406-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goodwin N |
Year: |
1998 |
Journal: |
MGI Direct Data Submission |
Title: |
An embryonic stem cell bank for producing deletion complexes in mice |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Briançon N |
Year: |
2006 |
Journal: |
EMBO J |
Title: |
In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping. |
Volume: |
25 |
Issue: |
6 |
Pages: |
1253-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ghai R |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. |
Volume: |
110 |
Issue: |
8 |
Pages: |
E643-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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|
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
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|
•
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
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|
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•
•
•
•
•
|
Publication |
First Author: |
Fisher SR |
Year: |
1997 |
Journal: |
Anim Genet |
Title: |
Genetic mapping of five human chromosome 4 orthologues to bovine chromosomes 6 and 17. |
Volume: |
28 |
Issue: |
4 |
Pages: |
253-7 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents a conserved region found in several lipid transport proteins, including vitellogenin, microsomal triglyceride transfer protein and apolipoprotein B-100 [].Vitellinogen precursors provide the major egg yolk proteins that are a source of nutrients during early development of oviparous vertebrates and invertebrates. Vitellinogen precursors are multi-domain apolipoproteins that are cleaved into distinct yolk proteins. Different vitellinogen precursors exist, which are composed of variable combinations of yolk protein components; however, the cleavage sites are conserved. In vertebrates, a complete vitellinogen is composed of an N-terminal signal peptide for export, followed by four regions that can be cleaved into yolk proteins: lipovitellin-1, phosvitin, lipovitellin-2, and a von Willebrand factor type D domain (YGP40) [, ].Microsomal triglyceride transfer protein (MTTP) is an endoplasmic reticulum lipid transfer protein involved in the biosynthesis and lipid loading of apolipoprotein B. MTTP is also involved in the late stage of CD1d trafficking in the lysosomal compartment, CD1d being the MHC I-like lipid antigen presenting molecule [].Apolipoprotein B can exist in two forms: B-100 and B-48. Apoliporotein B-100 is present on several lipoproteins, including very low-density lipoproteins (VLDL), intermediate density lipoproteins (IDL) and low density lipoproteins (LDL), and can assemble VLDL particles in the liver []. Apolipoprotein B-100 has been linked to the development of atherosclerosis. |
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•
•
•
•
•
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Publication |
First Author: |
Agarwal N |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD. |
Volume: |
7 |
Issue: |
1 |
Pages: |
13362 |
|
•
•
•
•
•
|
Publication |
First Author: |
Niwa H |
Year: |
2018 |
Journal: |
Nutrients |
Title: |
ChREBP Rather Than SHP Regulates Hepatic VLDL Secretion. |
Volume: |
10 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Tsai WC |
Year: |
2012 |
Journal: |
J Clin Invest |
Title: |
MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. |
Volume: |
122 |
Issue: |
8 |
Pages: |
2884-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ilacqua N |
Year: |
2022 |
Journal: |
J Cell Sci |
Title: |
A three-organelle complex made by wrappER contacts with peroxisomes and mitochondria responds to liver lipid flux changes. |
Volume: |
135 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kanuri G |
Year: |
2011 |
Journal: |
Lab Invest |
Title: |
Fructose-induced steatosis in mice: role of plasminogen activator inhibitor-1, microsomal triglyceride transfer protein and NKT cells. |
Volume: |
91 |
Issue: |
6 |
Pages: |
885-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sabui S |
Year: |
2017 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Adaptive regulation of pancreatic acinar mitochondrial thiamin pyrophosphate uptake process: possible involvement of epigenetic mechanism(s). |
Volume: |
313 |
Issue: |
5 |
Pages: |
G448-G455 |
|
•
•
•
•
•
|
Publication |
First Author: |
Olofsson SO |
Year: |
2005 |
Journal: |
J Intern Med |
Title: |
Apolipoprotein B: a clinically important apolipoprotein which assembles atherogenic lipoproteins and promotes the development of atherosclerosis. |
Volume: |
258 |
Issue: |
5 |
Pages: |
395-410 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
329
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4505
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4456
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Anderson TA |
Year: |
1998 |
Journal: |
Structure |
Title: |
The structural basis of lipid interactions in lipovitellin, a soluble lipoprotein. |
Volume: |
6 |
Issue: |
7 |
Pages: |
895-909 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson JR |
Year: |
2002 |
Journal: |
Biochemistry |
Title: |
Lipid-protein interactions in lipovitellin. |
Volume: |
41 |
Issue: |
30 |
Pages: |
9398-409 |
|
•
•
•
•
•
|
Publication |
First Author: |
Finn RN |
Year: |
2007 |
Journal: |
Biol Reprod |
Title: |
Vertebrate yolk complexes and the functional implications of phosvitins and other subdomains in vitellogenins. |
Volume: |
76 |
Issue: |
6 |
Pages: |
926-35 |
|
•
•
•
•
•
|