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Search results 1 to 100 out of 143 for Sarm1

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Category: Publication
Type Details Score
Publication
First Author: Gerdts J
Year: 2015
Journal: Science
Title: SARM1 activation triggers axon degeneration locally via NAD⁺ destruction.
Volume: 348
Issue: 6233
Pages: 453-7
Publication
First Author: Summers DW
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation.
Volume: 113
Issue: 41
Pages: E6271-E6280
Publication
First Author: Gilley J
Year: 2015
Journal: Cell Rep
Title: Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
Volume: 10
Issue: 12
Pages: 1974-81
Publication
First Author: Essuman K
Year: 2017
Journal: Neuron
Title: The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration.
Volume: 93
Issue: 6
Pages: 1334-1343.e5
Publication
First Author: Gilley J
Year: 2017
Journal: Cell Rep
Title: Sarm1 Deletion, but Not WldS, Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy.
Volume: 21
Issue: 1
Pages: 10-16
Publication
First Author: Viar K
Year: 2020
Journal: PLoS One
Title: Sarm1 knockout protects against early but not late axonal degeneration in experimental allergic encephalomyelitis.
Volume: 15
Issue: 6
Pages: e0235110
Publication  
First Author: Ozaki E
Year: 2020
Journal: Life Sci Alliance
Title: SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degeneration.
Volume: 3
Issue: 5
Publication  
First Author: Shen C
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Multiple domain interfaces mediate SARM1 autoinhibition.
Volume: 118
Issue: 4
Publication    
First Author: Sasaki Y
Year: 2020
Journal: Elife
Title: SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration.
Volume: 9
Publication
First Author: Carty M
Year: 2006
Journal: Nat Immunol
Title: The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.
Volume: 7
Issue: 10
Pages: 1074-81
Publication
First Author: Peng J
Year: 2010
Journal: Eur J Immunol
Title: SARM inhibits both TRIF- and MyD88-mediated AP-1 activation.
Volume: 40
Issue: 6
Pages: 1738-47
Publication
First Author: Belinda LW
Year: 2008
Journal: Mol Immunol
Title: SARM: a novel Toll-like receptor adaptor, is functionally conserved from arthropod to human.
Volume: 45
Issue: 6
Pages: 1732-42
Publication
First Author: Cheng Y
Year: 2019
Journal: Diabetes
Title: Sarm1 Gene Deficiency Attenuates Diabetic Peripheral Neuropathy in Mice.
Volume: 68
Issue: 11
Pages: 2120-2130
Publication
First Author: Doran CG
Year: 2021
Journal: J Biol Chem
Title: CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophages.
Volume: 297
Issue: 6
Pages: 101417
Publication
First Author: Wu T
Year: 2021
Journal: Cell Rep
Title: Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss.
Volume: 37
Issue: 3
Pages: 109872
Publication
First Author: Zhu C
Year: 2019
Journal: J Exp Med
Title: SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease.
Volume: 216
Issue: 4
Pages: 743-756
Publication
First Author: Miyamoto T
Year: 2024
Journal: J Biol Chem
Title: SARM1 is responsible for calpain-dependent dendrite degeneration in mouse hippocampal neurons.
Volume: 300
Issue: 2
Pages: 105630
Publication  
First Author: Gibbons L
Year: 2022
Journal: Front Neurosci
Title: SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration.
Volume: 16
Pages: 852114
Publication
First Author: Bloom AJ
Year: 2022
Journal: Mol Neurodegener
Title: Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients.
Volume: 17
Issue: 1
Pages: 1
Publication
First Author: White MA
Year: 2019
Journal: Acta Neuropathol Commun
Title: Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss.
Volume: 7
Issue: 1
Pages: 166
Publication
First Author: Sundaramoorthy V
Year: 2020
Journal: PLoS Pathog
Title: Novel role of SARM1 mediated axonal degeneration in the pathogenesis of rabies.
Volume: 16
Issue: 2
Pages: e1008343
Publication
First Author: Bratkowski M
Year: 2022
Journal: Neuron
Title: Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease.
Volume: 110
Issue: 22
Pages: 3711-3726.e16
Publication  
First Author: Ko KW
Year: 2020
Journal: J Cell Biol
Title: SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration.
Volume: 219
Issue: 8
Publication
First Author: Turkiew E
Year: 2017
Journal: J Peripher Nerv Syst
Title: Deletion of Sarm1 gene is neuroprotective in two models of peripheral neuropathy.
Volume: 22
Issue: 3
Pages: 162-171
Publication
First Author: Figley MD
Year: 2021
Journal: Neuron
Title: SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration.
Volume: 109
Issue: 7
Pages: 1118-1136.e11
Publication
First Author: Gould SA
Year: 2021
Journal: Cell Rep
Title: Sarm1 haploinsufficiency or low expression levels after antisense oligonucleotides delay programmed axon degeneration.
Volume: 37
Issue: 11
Pages: 110108
Publication  
First Author: Marion CM
Year: 2019
Journal: Exp Neurol
Title: Sarm1 deletion reduces axon damage, demyelination, and white matter atrophy after experimental traumatic brain injury.
Volume: 321
Pages: 113040
Publication  
First Author: Maynard ME
Year: 2020
Journal: Exp Neurol
Title: Sarm1 loss reduces axonal damage and improves cognitive outcome after repetitive mild closed head injury.
Volume: 327
Pages: 113207
Publication
First Author: Liu H
Year: 2021
Journal: Theranostics
Title: SARM1 promotes neuroinflammation and inhibits neural regeneration after spinal cord injury through NF-κB signaling.
Volume: 11
Issue: 9
Pages: 4187-4206
Publication  
First Author: Fernandes KA
Year: 2018
Journal: Exp Eye Res
Title: Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury.
Volume: 171
Pages: 54-61
Publication
First Author: Lin CW
Year: 2014
Journal: Innate Immun
Title: Neuronally-expressed Sarm1 regulates expression of inflammatory and antiviral cytokines in brains.
Volume: 20
Issue: 2
Pages: 161-72
Publication
First Author: Hughes RO
Year: 2021
Journal: Cell Rep
Title: Small Molecule SARM1 Inhibitors Recapitulate the SARM1(-/-) Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate.
Volume: 34
Issue: 1
Pages: 108588
Publication
First Author: Feriotti C
Year: 2022
Journal: Cell Rep
Title: Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity.
Volume: 40
Issue: 6
Pages: 111167
Publication
First Author: Jin L
Year: 2022
Journal: Cell Death Dis
Title: Astrocytic SARM1 promotes neuroinflammation and axonal demyelination in experimental autoimmune encephalomyelitis through inhibiting GDNF signaling.
Volume: 13
Issue: 9
Pages: 759
Publication
First Author: Horsefield S
Year: 2019
Journal: Science
Title: NAD+ cleavage activity by animal and plant TIR domains in cell death pathways.
Volume: 365
Issue: 6455
Pages: 793-799
Publication
First Author: Xiang L
Year: 2022
Journal: Cell Death Dis
Title: SARM1 deletion in parvalbumin neurons is associated with autism-like behaviors in mice.
Volume: 13
Issue: 7
Pages: 638
Publication  
First Author: Sasaki Y
Year: 2020
Journal: Exp Neurol
Title: cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons.
Volume: 329
Pages: 113252
Publication
First Author: Peters OM
Year: 2018
Journal: Hum Mol Genet
Title: Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis.
Volume: 27
Issue: 21
Pages: 3761-3771
Publication
First Author: Pan ZG
Year: 2018
Journal: Biochem Biophys Res Commun
Title: SARM1 deletion restrains NAFLD induced by high fat diet (HFD) through reducing inflammation, oxidative stress and lipid accumulation.
Volume: 498
Issue: 3
Pages: 416-423
Publication  
First Author: Fazal SV
Year: 2023
Journal: Front Cell Neurosci
Title: SARM1 detection in myelinating glia: sarm1/Sarm1 is dispensable for PNS and CNS myelination in zebrafish and mice.
Volume: 17
Pages: 1158388
Publication  
First Author: Finnegan LK
Year: 2022
Journal: Int J Mol Sci
Title: SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration.
Volume: 23
Issue: 3
Publication
First Author: Ward A
Year: 2022
Journal: PLoS One
Title: Lack of the immune adaptor molecule SARM1 accelerates disease in prion infected mice and is associated with increased mitochondrial respiration and decreased expression of NRF2.
Volume: 17
Issue: 5
Pages: e0267720
Publication
First Author: Bradshaw DV Jr
Year: 2021
Journal: Acta Neuropathol Commun
Title: Genetic inactivation of SARM1 axon degeneration pathway improves outcome trajectory after experimental traumatic brain injury based on pathological, radiological, and functional measures.
Volume: 9
Issue: 1
Pages: 89
Publication  
First Author: Collins JM
Year: 2022
Journal: Neurobiol Dis
Title: Sarm1 knockout modifies biomarkers of neurodegeneration and spinal cord circuitry but not disease progression in the mSOD1G93A mouse model of ALS.
Volume: 172
Pages: 105821
Publication
First Author: Osterloh JM
Year: 2012
Journal: Science
Title: dSarm/Sarm1 is required for activation of an injury-induced axon death pathway.
Volume: 337
Issue: 6093
Pages: 481-4
Publication
First Author: Chen CY
Year: 2011
Journal: J Cell Biol
Title: Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology.
Volume: 193
Issue: 4
Pages: 769-84
Publication
First Author: Szretter KJ
Year: 2009
Journal: J Virol
Title: The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis.
Volume: 83
Issue: 18
Pages: 9329-38
Publication    
First Author: Sasaki Y
Year: 2016
Journal: Elife
Title: NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.
Volume: 5
Publication
First Author: Kim Y
Year: 2007
Journal: J Exp Med
Title: MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival.
Volume: 204
Issue: 9
Pages: 2063-74
Publication    
First Author: Loreto A
Year: 2021
Journal: Elife
Title: Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1.
Volume: 10
Publication
First Author: Uccellini MB
Year: 2020
Journal: Cell Rep
Title: Passenger Mutations Confound Phenotypes of SARM1-Deficient Mice.
Volume: 31
Issue: 1
Pages: 107498
Publication
First Author: Jiang Y
Year: 2020
Journal: Nature
Title: The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative SARM1.
Volume: 588
Issue: 7839
Pages: 658-663
Publication    
First Author: Walker LJ
Year: 2017
Journal: Elife
Title: MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.
Volume: 6
Publication
First Author: Summers DW
Year: 2014
Journal: J Neurosci
Title: Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons.
Volume: 34
Issue: 28
Pages: 9338-50
Publication  
First Author: Lin CW
Year: 2014
Journal: Brain Behav Immun
Title: Sarm1, a neuronal inflammatory regulator, controls social interaction, associative memory and cognitive flexibility in mice.
Volume: 37
Pages: 142-51
Publication  
First Author: Geisler S
Year: 2019
Journal: JCI Insight
Title: Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program.
Volume: 4
Issue: 17
Publication  
First Author: Gould SA
Year: 2021
Journal: Exp Neurol
Title: Protection against oxaliplatin-induced mechanical and thermal hypersensitivity in Sarm1-/- mice.
Volume: 338
Pages: 113607
Publication  
First Author: Peters OM
Year: 2021
Journal: Neurobiol Dis
Title: Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease.
Volume: 155
Pages: 105368
Publication
First Author: Gerdts J
Year: 2013
Journal: J Neurosci
Title: Sarm1-mediated axon degeneration requires both SAM and TIR interactions.
Volume: 33
Issue: 33
Pages: 13569-80
Publication
First Author: Killackey SA
Year: 2019
Journal: Mol Cell Biochem
Title: The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1.
Volume: 453
Issue: 1-2
Pages: 187-196
Publication
First Author: Liu K
Year: 2021
Journal: Cell Metab
Title: Metabolic stress drives sympathetic neuropathy within the liver.
Volume: 33
Issue: 3
Pages: 666-675.e4
Publication
First Author: Ziogas NK
Year: 2018
Journal: J Neurosci
Title: Primary Traumatic Axonopathy in Mice Subjected to Impact Acceleration: A Reappraisal of Pathology and Mechanisms with High-Resolution Anatomical Methods.
Volume: 38
Issue: 16
Pages: 4031-4047
Publication
First Author: Molday LL
Year: 2007
Journal: J Biol Chem
Title: Retinoschisin (RS1), the protein encoded by the X-linked retinoschisis gene, is anchored to the surface of retinal photoreceptor and bipolar cells through its interactions with a Na/K ATPase-SARM1 complex.
Volume: 282
Issue: 45
Pages: 32792-801
Publication
First Author: Carty M
Year: 2019
Journal: Immunity
Title: Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM.
Volume: 50
Issue: 6
Pages: 1412-1424.e6
Publication
First Author: Hou YJ
Year: 2013
Journal: J Immunol
Title: SARM is required for neuronal injury and cytokine production in response to central nervous system viral infection.
Volume: 191
Issue: 2
Pages: 875-83
Publication
First Author: Pudla M
Year: 2011
Journal: Infect Immun
Title: Burkholderia pseudomallei-induced expression of a negative regulator, sterile-alpha and Armadillo motif-containing protein, in mouse macrophages: a possible mechanism for suppression of the MyD88-independent pathway.
Volume: 79
Issue: 7
Pages: 2921-7
Publication
First Author: Baral P
Year: 2013
Journal: Infect Immun
Title: Sterile-α- and armadillo motif-containing protein inhibits the TRIF-dependent downregulation of signal regulatory protein α to interfere with intracellular bacterial elimination in Burkholderia pseudomallei-infected mouse macrophages.
Volume: 81
Issue: 9
Pages: 3463-71
Publication
First Author: Yong Y
Year: 2020
Journal: Sci Rep
Title: Regulation of degenerative spheroids after injury.
Volume: 10
Issue: 1
Pages: 15472
Publication
First Author: Gürtler C
Year: 2014
Journal: J Immunol
Title: SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter.
Volume: 192
Issue: 10
Pages: 4821-32
Publication
First Author: Shacham-Silverberg V
Year: 2018
Journal: Cell Death Dis
Title: Phosphatidylserine is a marker for axonal debris engulfment but its exposure can be decoupled from degeneration.
Volume: 9
Issue: 11
Pages: 1116
Publication
First Author: Panneerselvam P
Year: 2013
Journal: Cell Death Differ
Title: T-cell death following immune activation is mediated by mitochondria-localized SARM.
Volume: 20
Issue: 3
Pages: 478-89
Publication
First Author: Krus KL
Year: 2022
Journal: Cell Rep
Title: Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy.
Volume: 39
Issue: 13
Pages: 111001
Publication
First Author: Kant S
Year: 2019
Journal: Nat Commun
Title: Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis.
Volume: 10
Issue: 1
Pages: 4223
Publication
First Author: Jung J
Year: 2023
Journal: Neuron
Title: mRNA transport, translation, and decay in adult mammalian central nervous system axons.
Volume: 111
Issue: 5
Pages: 650-668.e4
Publication
First Author: Bjanes E
Year: 2021
Journal: PLoS Pathog
Title: Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection.
Volume: 17
Issue: 10
Pages: e1009967
Publication
First Author: Mukherjee P
Year: 2013
Journal: Immunity
Title: Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death.
Volume: 38
Issue: 4
Pages: 705-16
Publication
First Author: Yang S
Year: 2024
Journal: Mol Neurodegener
Title: NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport.
Volume: 19
Issue: 1
Pages: 13
Publication
First Author: Zhou N
Year: 2019
Journal: Protein Cell
Title: Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition.
Volume: 10
Issue: 2
Pages: 87-103
Publication
First Author: Mink M
Year: 2001
Journal: Genomics
Title: A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans.
Volume: 74
Issue: 2
Pages: 234-44
Publication
First Author: Li S
Year: 2011
Journal: Immunity
Title: Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.
Volume: 35
Issue: 3
Pages: 426-40
Publication
First Author: Balounová J
Year: 2019
Journal: Nat Commun
Title: Toll-like receptor 2 expression on c-kit+ cells tracks the emergence of embryonic definitive hematopoietic progenitors.
Volume: 10
Issue: 1
Pages: 5176
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582