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Search results 101 to 125 out of 125 for Mnd1

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0.019s
Type Details Score
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: Mus pahari
Pseudogene
Type: pseudogene
Organism: Mus spretus
Allele
Name: meiotic nuclear divisions 1; gene trap RRS590, BayGenomics
Allele Type: Gene trapped
Attribute String: Null/knockout
Protein Domain
Type: Domain
Description: This HTH domain is found in Mnd1 from S. cerevisiae. The Mnd1 protein forms a complex with Hop2 to promote homologous chromosome pairing and meiotic double-strand break repair [].
Genotype
Symbol: Mnd1/Mnd1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Kang HA
Year: 2015
Journal: Nucleic Acids Res
Title: Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination.
Volume: 43
Issue: 7
Pages: 3841-56
Protein Domain
Type: Domain
Description: This domain is found at the C-terminal region of Hop2 and Mnd1 proteins. In meiotic DNA recombination, the Hop2-Mnd1 complex promotes Dmc1-mediated single-stranded DNA (ssDNA) invasion into homologous chromosomes to form a synaptic complex. Hop2 (for homologous pairing; also known as TBPIP) is expressed specifically during meiosis, same as Mnd1 (for meiotic nuclear divisions 1). The C-terminal region of both Hop2 and Mnd1, folds into three α-helices that are interrupted by two short non-helical regions. These α-helices of the two proteins together form a parallel coiled coil that provides the major interface for heterodimer formation. The non-helical regions form substantially kinked junctions between adjacent leucine zippers: the LZ1-LZ2 and LZ2-LZ3 junctions.This domain is the C-terminal segment of Hop2 and Mnd1 which folds back onto the C-terminal leucine zipper (LZ3) to form a helical bundle-like structure, hence designated LZ3wCH (for LZ3 with capping helices). The LZ3wCH region plays a role in interacting with the Dmc1 nucleofilament [].
Genotype
Symbol: Mnd1/Mnd1 Psmc3ip/Psmc3ip
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: false