Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3846181 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-06-01 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914225 |
Pattern: |
Regionally restricted |
Stage: |
TS25 |
Assay Id: |
MGI:3846182 |
Age: |
embryonic day 17.0 |
Image: |
5A |
Note: |
Expression is strong in proliferating chondrocytes and is weak in other resting and hypertrophic chondrocytes in the epiphysial growth plates. |
Specimen Label: |
5A |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3846181 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-06-01 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914225 |
Pattern: |
Regionally restricted |
Stage: |
TS25 |
Assay Id: |
MGI:3846182 |
Age: |
embryonic day 17.0 |
Image: |
5C |
Note: |
Expression is strong in proliferating chondrocytes and is weak in other resting and hypertrophic chondrocytes in the epiphysial growth plates. |
Specimen Label: |
5C |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3846181 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-06-01 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914228 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3846182 |
Age: |
postnatal day 35 |
Image: |
5E |
Note: |
Expression is strong in proliferating chondrocytes and is absent in resting and hypertrophic chondrocytes. |
Specimen Label: |
5E |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3846181 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-06-01 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914228 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3846182 |
Age: |
postnatal day 35 |
Image: |
5G |
Note: |
Expression is strong in proliferating chondrocytes and is absent in resting and hypertrophic chondrocytes. |
Specimen Label: |
5G |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3846181 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-06-01 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914228 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3846182 |
Age: |
postnatal day 35 |
Image: |
5I |
Note: |
In the metaphysis expression is strong in osteoblasts and osteoclasts on the bone surface and is weak in osteocytes. |
Specimen Label: |
5I |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6696294 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-05-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3557627 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:6696399 |
Age: |
postnatal newborn |
|
Note: |
Expression is in preodontoblasts and odontoblasts in the ifirst molar. |
Specimen Label: |
Table 2 E19.5 (newborn) |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6696294 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-05-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3289722 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:6696399 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression is in the first molar enamel knot. |
Specimen Label: |
Table 2 E14.5 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6696294 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-05-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3289722 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:6696399 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression is in the ectomesenchyme. |
Specimen Label: |
4D |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5502601 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-08-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1701523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:5502620 |
Age: |
embryonic day 15.5 |
|
Note: |
Expression is in the muscular walls. |
Specimen Label: |
2R,S,T |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5502601 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-08-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1761821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5502620 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
2J |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5502611 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2013-08-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1761820 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:5502652 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
4F |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5502611 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2013-08-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1761821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5502652 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
4G |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5502611 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2013-08-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1761821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5502652 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
S1D |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5502611 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2013-08-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1761821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5502652 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
6C inset |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6696294 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-05-06 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:2672024 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6696399 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
5I |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6696294 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-05-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3808522 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:6696399 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression is in the inner dental epithelium of the incisor and first molar. |
Specimen Label: |
Table 2 E14.5 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6696294 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-05-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3809122 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:6696399 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression is in the first molar enamel knot. |
Specimen Label: |
Table 2 E14.5 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sund KL |
Year: |
2009 |
Journal: |
Hum Mol Genet |
Title: |
Analysis of Ellis van Creveld syndrome gene products: implications for cardiovascular development and disease. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1813-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishikawa H |
Year: |
2012 |
Journal: |
Curr Biol |
Title: |
Proteomic analysis of mammalian primary cilia. |
Volume: |
22 |
Issue: |
5 |
Pages: |
414-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakatomi M |
Year: |
2013 |
Journal: |
J Dent Res |
Title: |
Evc regulates a symmetrical response to Shh signaling in molar development. |
Volume: |
92 |
Issue: |
3 |
Pages: |
222-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burnicka-Turek O |
Year: |
2016 |
Journal: |
Hum Mol Genet |
Title: |
Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms. |
Volume: |
25 |
Issue: |
14 |
Pages: |
3011-3028 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
Year: |
2001 |
|
Title: |
LocusLink Collaboration |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Allele |
Name: |
EvC ciliary complex subunit 2; targeted mutation 1.1, Yuji Mishina |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
EvC ciliary complex subunit 1; targeted mutation 1, Judith A Goodship |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Evc/Evc |
Background: |
involves: 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Evc2/Evc2 |
Background: |
involves: 129X1/SvJ * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
EVC is a protein mutated in the human chondroectodermal dysplasia Ellis-van Creveld syndrome. Limbin or EVC2 interacts with AVC []. They act as positive mediators of Hedgehog signaling and play a critical role in bone formation and skeletal development []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1220
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
557
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
571
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruiz-Perez VL |
Year: |
2007 |
Journal: |
Development |
Title: |
Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. |
Volume: |
134 |
Issue: |
16 |
Pages: |
2903-12 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1005
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
167
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
144
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
629
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
857
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
627
|
Fragment?: |
false |
|
•
•
•
•
•
|