|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 501 to 582 out of 582 for Il4ra

<< First    < Previous  |  Next >    Last >>
0.024s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Allele
Il4ra<tm1(IL4RA)Smoc> | MGI:7290519
Name: interleukin 4 receptor, alpha; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Il4ra<em2Smoc> | MGI:7290521
Name: interleukin 4 receptor, alpha; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Genotype
Genotype
Symbol: Il4ppq/Il4ppq
Background: involves: NZB/Slc * NZW/Slc
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Protein
P16382-2
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
•
•
•
•
•
Protein
P16382-3
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: false
•
•
•
•
•
Strain
MGI:6354928 | C57BL/6J-Il4ra<tm1(IL4R)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
•
•
•
•
•
Allele
Il4ra<em1Amen> | MGI:7334731
Name: interleukin 4 receptor, alpha; endonuclease-mediated mutation 1, Sarah Amend
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Strain
MGI:7334732 | FVB/NJ-Il4ra<em1Amen>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Allele
Il4ra<tm3.1Tch> | MGI:4455123
 
Name: interleukin 4 receptor, alpha; targeted mutation 3.1, Talal A Chatila
Allele Type: Targeted
•
•
•
•
•
Strain
MGI:4455326 | C.129X1-Il4ra<tm3.1Tch>
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Strain
MGI:4455180 | C.129X1-Il4ra<tm3.1Tch>/J
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Genotype
Genotype
Symbol: Il4ra/Il4ra
Background: C.129X1-Il4ra
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Publication
22287709 | J:181250
First Author: Bazett M
Year: 2012
Journal: J Immunol
Title: Strain-dependent airway hyperresponsiveness and a chromosome 7 locus of elevated lymphocyte numbers in cystic fibrosis transmembrane conductance regulator-deficient mice.
Volume: 188
Issue: 5
Pages: 2297-304
•
•
•
•
•
Publication
28193830 | J:247856
First Author: Braune J
Year: 2017
Journal: J Immunol
Title: IL-6 Regulates M2 Polarization and Local Proliferation of Adipose Tissue Macrophages in Obesity.
Volume: 198
Issue: 7
Pages: 2927-2934
•
•
•
•
•
Publication
1913811 | -
First Author: Nicola NA
Year: 1991
Journal: Cell
Title: Subunit promiscuity among hemopoietic growth factor receptors.
Volume: 67
Issue: 1
Pages: 1-4
•
•
•
•
•
Publication
7946053 | -
First Author: Leonard WJ
Year: 1994
Journal: Curr Opin Immunol
Title: The defective gene in X-linked severe combined immunodeficiency encodes a shared interleukin receptor subunit: implications for cytokine pleiotropy and redundancy.
Volume: 6
Issue: 4
Pages: 631-5
•
•
•
•
•
Protein Domain
IPR003532 | Short_hematopoietin_rcpt_2_CS
Type: Conserved_site
Description: A number of receptors for lymphokines, hematopoietic growth factors and growth hormone-related molecules have been found to share a common binding domain. These receptors are designated as hematopoietin receptors []and the corresponding ligands as hematopoietins. Further, hematopoietins have been subdivided into two major structural groups: large (long) and small (short) hematopoietins.One subset of individual receptor chains that are part of receptor complexes for small hematopoietins contain common structural elements: an extracellular receptor domain that contains an immunoglobulin-like region at the N-terminal end; a transmembrane domain; and a short cytoplasmic domain. They define a structural subgroup containing the following chains:Granulocyte/macrophage colony stimulating factor receptor alpha (GMCSFRA)Interleukin-3 receptor alpha chain (IL3RA)Interleukin-5 receptor alpha chain (IL5RA)Interleukin-13 receptor alpha-1 chain (IL13RA1)Interleukin-13 receptor alpha-2 chain (IL13RA2)GMCSFRA, IL3RA or IL5RA chains of this subgroup bind to their cognate cytokines: GM-CSF, IL-3 and IL-5, with a common beta chain, KH97/AIC2B []. Either IL13RA1 chain or IL13RA2 chain form the IL13R complex together with IL4RA chain. IL-4 can compete with IL-13 to bind to either IL13R form [].
•
•
•
•
•
Protein Domain
IPR003531 | Hempt_rcpt_S_F1_CS
Type: Conserved_site
Description: A number of receptors for lymphokines, hematopoietic growth factors andgrowth hormone-related molecules have been found to share a common bindingdomain. These receptors are designated as hematopoietin receptors []andthe corresponding ligands as hematopoietins. Further, hematopoietins have beensubdivided into two major structural groups: Large/long and small/shorthematopoietins.One subset of individual receptor chains that are part of receptor complexes for small hematopoietins are structurally related such that their extracellular parts strictly contain the 200 amino-acids hematopoietin domain (duplicated in IL-3/-5/GM-CSF beta chain receptors KH97/AIC2B and AIC2A). They define a structural subgroup containing the following chains: Interleukin-2 receptor beta chain (IL2RB), Interleukin-2 receptor common gamma chain (IL2RG), Interleukin-3 receptor beta chain (AIC2A), Interleukin-3/-5/GM-CSF receptor common beta chain (KH97/AIC2B), Interleukin-4 receptor alpha chain (IL4RA), Interleukin-7 receptor alpha chain (IL7RA), Interleukin-9 receptor alpha chain (IL9RA). A schematic representation of the structure of these receptors is shown below: +----------------------------------------xxxxxxx---------------------------+| C C C C Extracellular XXXXXXX Cytoplasmic |+-|-|-------|--|-------------------------xxxxxxx---------------------------+| | | | Transmembrane+-+ +--+IL4RA, IL7RA and IL9RA are specific alpha chain receptors for IL-4, IL-7and IL-9 respectively, whereas IL2RB is common to IL-2 and IL-15 (IL2RA andIL15RA are not members of the hematopoietin receptor superfamily). IL2RG ispart of IL-2, IL-15, IL-7, IL-9 and IL-4 form I receptor complexes [].KH97/AIC2B chain is part of GM-CSF, IL-3 and IL-5 receptor complexes and inthe mouse, AIC2B can be substituted by AIC2A, an IL-3 specific beta chainreceptor []. Together with either IL13RA1 or IL13RA2, IL4RA is also partof the IL-13 receptor complex for which IL-4 can compete with IL-13 (IL-4receptor complex form II) [].
•
•
•
•
•
Publication
1400369 | -
First Author: Boulay JL
Year: 1992
Journal: J Biol Chem
Title: The interleukin-4-related lymphokines and their binding to hematopoietin receptors.
Volume: 267
Issue: 29
Pages: 20525-8
•
•
•
•
•
Protein
Q01114
Organism: Mus musculus/domesticus
Length: 468  
Fragment?: false
•
•
•
•
•
Protein
P26952
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
•
•
•
•
•
Protein
P21183
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
•
•
•
•
•
Protein
Q9JHX3
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
•
•
•
•
•
Protein
P16297
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
•
•
•
•
•
Protein
O88786
Organism: Mus musculus/domesticus
Length: 383  
Fragment?: false
•
•
•
•
•
Protein
A0A286YE20
Organism: Mus musculus/domesticus
Length: 196  
Fragment?: false
•
•
•
•
•
Protein
Q78PA5
Organism: Mus musculus/domesticus
Length: 468  
Fragment?: false
•
•
•
•
•
Protein
A9P557
Organism: Mus musculus/domesticus
Length: 363  
Fragment?: false
•
•
•
•
•
Protein
B0QZX1
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: true
•
•
•
•
•
Protein
Q8CBU1
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
•
•
•
•
•
Protein
Q8C2G1
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: false
•
•
•
•
•
Protein
Q2M2M3
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
•
•
•
•
•
Protein
Q3TA82
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: true
•
•
•
•
•
Protein
Q3UBS8
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
•
•
•
•
•
Protein
B7ZD65
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
•
•
•
•
•
Protein
A0A286YE23
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
•
•
•
•
•
Protein
A2AVE0
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: false
•
•
•
•
•
Protein
Q3TAI3
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
•
•
•
•
•
Protein
A2AGH5
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
•
•
•
•
•
Protein
Q8R308
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
•
•
•
•
•
Protein
B7ZN65
Organism: Mus musculus/domesticus
Length: 390  
Fragment?: false
•
•
•
•
•
Protein
Q05A81
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
•
•
•
•
•
Protein
Q3TEQ2
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
•
•
•
•
•
Protein
A9P558
Organism: Mus musculus/domesticus
Length: 253  
Fragment?: false
•
•
•
•
•
Protein
Q4KKX7
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
•
•
•
•
•
Protein
Q6PEU8
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
•
•
•
•
•
Protein
O09030
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
•
•
•
•
•
Protein
P16872
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
•
•
•
•
•
Protein
Q00941
Organism: Mus musculus/domesticus
Length: 388  
Fragment?: false
•
•
•
•
•
Protein
P26954
Organism: Mus musculus/domesticus
Length: 878  
Fragment?: false
•
•
•
•
•
Protein
P26955
Organism: Mus musculus/domesticus
Length: 896  
Fragment?: false
•
•
•
•
•
Protein
P34902
Organism: Mus musculus/domesticus
Length: 369  
Fragment?: false
•
•
•
•
•
Protein
A2VCP1
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: true
•
•
•
•
•
Protein
Q3U2T6
Organism: Mus musculus/domesticus
Length: 896  
Fragment?: false
•
•
•
•
•
Protein
Q3U905
Organism: Mus musculus/domesticus
Length: 810  
Fragment?: false
•
•
•
•
•
Protein
Q3V057
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
•
•
•
•
•
Protein
Q3UPA9
Organism: Mus musculus/domesticus
Length: 369  
Fragment?: false
•
•
•
•
•
Protein
A0A2R8VK01
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
•
•
•
•
•
Protein
Q5FW78
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: false
•
•
•
•
•
Protein
Q3UPQ9
Organism: Mus musculus/domesticus
Length: 399  
Fragment?: false
•
•
•
•
•
Protein
Q8C1Z3
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
•
•
•
•
•
Protein
Q3U3Z0
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
•
•
•
•
•
Protein
Q3U3P4
Organism: Mus musculus/domesticus
Length: 790  
Fragment?: true
•
•
•
•
•
Protein
Q8BNM4
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
•
•
•
•
•
Protein
Q3U2L4
Organism: Mus musculus/domesticus
Length: 652  
Fragment?: true
•
•
•
•
•
Protein
B2RWT6
Organism: Mus musculus/domesticus
Length: 388  
Fragment?: false
•
•
•
•
•
Protein
Q8C9W4
Organism: Mus musculus/domesticus
Length: 456  
Fragment?: true
•
•
•
•
•
Protein
A0A2I3BRC2
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: false
•
•
•
•
•
Protein
W8DLM5
Organism: Mus musculus/domesticus
Length: 782  
Fragment?: true
•
•
•
•
•
Protein
Q3U1Z1
Organism: Mus musculus/domesticus
Length: 769  
Fragment?: false
•
•
•
•
•
Protein
Q3U1W0
Organism: Mus musculus/domesticus
Length: 878  
Fragment?: false
•
•
•
•
•
Protein
A0A2R8VHE8
Organism: Mus musculus/domesticus
Length: 769  
Fragment?: false
•
•
•
•
•
Protein
Q3TB34
Organism: Mus musculus/domesticus
Length: 670  
Fragment?: true
•
•
•
•
•
Protein
Q544A9
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: true
•
•
•
•
•
Protein
Q3UE66
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: false
•
•
•
•
•
Protein
Q8QZX9
Organism: Mus musculus/domesticus
Length: 896  
Fragment?: false
•
•
•
•
•
Protein
Q3U241
Organism: Mus musculus/domesticus
Length: 878  
Fragment?: false
•
•
•
•
•
Protein
P48356
Organism: Mus musculus/domesticus
Length: 1162  
Fragment?: false
•
•
•
•
•
Protein
Q640Q2
Organism: Mus musculus/domesticus
Length: 818  
Fragment?: false
•
•
•
•
•
Protein
Q3UNU8
Organism: Mus musculus/domesticus
Length: 892  
Fragment?: false
•
•
•
•
•
Protein
Q3US58
Organism: Mus musculus/domesticus
Length: 894  
Fragment?: false
•
•
•
•
•
Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom