Type |
Details |
Score |
Publication |
First Author: |
Kelley TJ |
Year: |
2000 |
Journal: |
J Clin Invest |
Title: |
In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium. |
Volume: |
106 |
Issue: |
3 |
Pages: |
403-10 |
|
•
•
•
•
•
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Publication |
First Author: |
Riazanski V |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
TRPC6 channel translocation into phagosomal membrane augments phagosomal function. |
Volume: |
112 |
Issue: |
47 |
Pages: |
E6486-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
McDaniel N |
Year: |
2005 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Role of Na-K-2Cl cotransporter-1 in gastric secretion of nonacidic fluid and pepsinogen. |
Volume: |
289 |
Issue: |
3 |
Pages: |
G550-60 |
|
•
•
•
•
•
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Publication |
First Author: |
Saadane A |
Year: |
2005 |
Journal: |
J Allergy Clin Immunol |
Title: |
Role of IL-10 deficiency in excessive nuclear factor-kappaB activation and lung inflammation in cystic fibrosis transmembrane conductance regulator knockout mice. |
Volume: |
115 |
Issue: |
2 |
Pages: |
405-11 |
|
•
•
•
•
•
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Publication |
First Author: |
Soltys J |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Functional IL-10 deficiency in the lung of cystic fibrosis (cftr(-/-)) and IL-10 knockout mice causes increased expression and function of B7 costimulatory molecules on alveolar macrophages. |
Volume: |
168 |
Issue: |
4 |
Pages: |
1903-10 |
|
•
•
•
•
•
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Publication |
First Author: |
Becker KA |
Year: |
2010 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death. |
Volume: |
403 |
Issue: |
3-4 |
Pages: |
368-74 |
|
•
•
•
•
•
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Publication |
First Author: |
Teichgräber V |
Year: |
2008 |
Journal: |
Nat Med |
Title: |
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. |
Volume: |
14 |
Issue: |
4 |
Pages: |
382-91 |
|
•
•
•
•
•
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Publication |
First Author: |
Ziobro R |
Year: |
2013 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Ceramide mediates lung fibrosis in cystic fibrosis. |
Volume: |
434 |
Issue: |
4 |
Pages: |
705-9 |
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•
•
•
•
•
|
Publication |
First Author: |
Yefimova MG |
Year: |
2016 |
Journal: |
Hum Mol Genet |
Title: |
Myelinosomes act as natural secretory organelles in Sertoli cells to prevent accumulation of aggregate-prone mutant Huntingtin and CFTR. |
Volume: |
25 |
Issue: |
19 |
Pages: |
4170-4185 |
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•
•
•
•
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Publication |
First Author: |
Pariano M |
Year: |
2021 |
Journal: |
Int J Mol Sci |
Title: |
Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity. |
Volume: |
22 |
Issue: |
12 |
|
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•
•
•
•
•
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Publication |
First Author: |
Cigana C |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections. |
Volume: |
6 |
|
Pages: |
21465 |
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•
•
•
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Publication |
First Author: |
Gardner AI |
Year: |
2021 |
Journal: |
J Biol Chem |
Title: |
Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis. |
Volume: |
296 |
|
Pages: |
100650 |
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•
•
•
•
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Publication |
First Author: |
Molina SA |
Year: |
2017 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner. |
Volume: |
312 |
Issue: |
5 |
Pages: |
L688-L702 |
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•
•
•
•
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Publication |
First Author: |
Ma J |
Year: |
2021 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Neutrophil elastase-regulated macrophage sheddome/secretome and phagocytic failure. |
Volume: |
321 |
Issue: |
3 |
Pages: |
L555-L565 |
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•
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Publication |
First Author: |
Kelley TJ |
Year: |
1998 |
Journal: |
J Clin Invest |
Title: |
Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells. |
Volume: |
102 |
Issue: |
6 |
Pages: |
1200-7 |
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•
•
•
•
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Publication |
First Author: |
Loeven NA |
Year: |
2021 |
Journal: |
mBio |
Title: |
The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection. |
Volume: |
12 |
Issue: |
5 |
Pages: |
e0209821 |
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•
•
•
•
•
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Publication |
First Author: |
Nyström EEL |
Year: |
2021 |
Journal: |
Science |
Title: |
An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function. |
Volume: |
372 |
Issue: |
6539 |
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|
•
•
•
•
•
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Publication |
First Author: |
De Lisle RC |
Year: |
2001 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Changes in the exocrine pancreas secondary to altered small intestinal function in the CF mouse. |
Volume: |
281 |
Issue: |
4 |
Pages: |
G899-906 |
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•
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•
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Publication |
First Author: |
Cressman VL |
Year: |
1998 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
The relationship of chronic mucin secretion to airway disease in normal and CFTR-deficient mice. |
Volume: |
19 |
Issue: |
6 |
Pages: |
853-66 |
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•
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•
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Publication |
First Author: |
Canale-Zambrano JC |
Year: |
2010 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Toll-like receptor-4 genotype influences the survival of cystic fibrosis mice. |
Volume: |
299 |
Issue: |
2 |
Pages: |
G381-90 |
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Publication |
First Author: |
Öz HH |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis. |
Volume: |
41 |
Issue: |
11 |
Pages: |
111797 |
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•
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Publication |
First Author: |
Hinojosa-Kurtzberg AM |
Year: |
2003 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Novel MUC1 splice variants contribute to mucin overexpression in CFTR-deficient mice. |
Volume: |
284 |
Issue: |
5 |
Pages: |
G853-62 |
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•
•
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Publication |
First Author: |
Freedman SD |
Year: |
1999 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice. |
Volume: |
96 |
Issue: |
24 |
Pages: |
13995-4000 |
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•
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Publication |
First Author: |
Becker KA |
Year: |
2021 |
Journal: |
Infect Immun |
Title: |
Acid Ceramidase Rescues Cystic Fibrosis Mice from Pulmonary Infections. |
Volume: |
89 |
Issue: |
2 |
|
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•
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Publication |
First Author: |
Solymosi EA |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Chloride transport-driven alveolar fluid secretion is a major contributor to cardiogenic lung edema. |
Volume: |
110 |
Issue: |
25 |
Pages: |
E2308-16 |
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Publication |
First Author: |
Manson ME |
Year: |
2012 |
Journal: |
J Lipid Res |
Title: |
Regulatory role of β-arrestin-2 in cholesterol processing in cystic fibrosis epithelial cells. |
Volume: |
53 |
Issue: |
7 |
Pages: |
1268-76 |
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Publication |
First Author: |
Walker NM |
Year: |
2011 |
Journal: |
Acta Physiol (Oxf) |
Title: |
Functional activity of Pat-1 (Slc26a6) Cl(−)/HCO₃(−) exchange in the lower villus epithelium of murine duodenum. |
Volume: |
201 |
Issue: |
1 |
Pages: |
21-31 |
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Publication |
First Author: |
Song Y |
Year: |
2012 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Deletion of Slc26a6 alters the stoichiometry of apical Cl-/HCO-3 exchange in mouse pancreatic duct. |
Volume: |
303 |
Issue: |
8 |
Pages: |
C815-24 |
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First Author: |
Moretti S |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis. |
Volume: |
8 |
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Pages: |
14017 |
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First Author: |
Henry CO |
Year: |
2016 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
In vitro and in vivo evidence for an inflammatory role of the calcium channel TRPV4 in lung epithelium: Potential involvement in cystic fibrosis. |
Volume: |
311 |
Issue: |
3 |
Pages: |
L664-75 |
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Publication |
First Author: |
Zhang PX |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis transmembrane conductance regulator. |
Volume: |
190 |
Issue: |
10 |
Pages: |
5196-206 |
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Publication |
First Author: |
Guillemot L |
Year: |
2014 |
Journal: |
Biochimie |
Title: |
Cytosolic phospholipase A2α enhances mouse mortality induced by Pseudomonas aeruginosa pulmonary infection via interleukin 6. |
Volume: |
107 Pt A |
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Pages: |
95-104 |
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First Author: |
Li M |
Year: |
2017 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
CFTR-associated ligand is a negative regulator of Mrp2 expression. |
Volume: |
312 |
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1 |
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C40-C46 |
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First Author: |
Saadane A |
Year: |
2007 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Parthenolide inhibits IkappaB kinase, NF-kappaB activation, and inflammatory response in cystic fibrosis cells and mice. |
Volume: |
36 |
Issue: |
6 |
Pages: |
728-36 |
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First Author: |
Woods PS |
Year: |
2015 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
TGF-β-induced IL-6 prevents development of acute lung injury in influenza A virus-infected F508del CFTR-heterozygous mice. |
Volume: |
308 |
Issue: |
11 |
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L1136-44 |
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First Author: |
Khatri IA |
Year: |
2001 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Characteristics of rodent intestinal mucin Muc3 and alterations in a mouse model of human cystic fibrosis. |
Volume: |
280 |
Issue: |
6 |
Pages: |
G1321-30 |
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First Author: |
Jiang H |
Year: |
2017 |
Journal: |
J Exp Med |
Title: |
Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders. |
Volume: |
214 |
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11 |
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3219-3238 |
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First Author: |
Meissner A |
Year: |
2012 |
Journal: |
Circulation |
Title: |
Tumor necrosis factor-α-mediated downregulation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-1-phosphate signaling in a mouse model of heart failure. |
Volume: |
125 |
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22 |
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2739-50 |
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First Author: |
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Year: |
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Journal: |
Am J Physiol Cell Physiol |
Title: |
Native and recombinant Slc26a3 (downregulated in adenoma, Dra) do not exhibit properties of 2Cl-/1HCO3- exchange. |
Volume: |
300 |
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First Author: |
Renga G |
Year: |
2018 |
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Cell Rep |
Title: |
IL-9 and Mast Cells Are Key Players of Candida albicans Commensalism and Pathogenesis in the Gut. |
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23 |
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1767-1778 |
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First Author: |
Grassmé H |
Year: |
2017 |
Journal: |
Cell Host Microbe |
Title: |
β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections. |
Volume: |
21 |
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707-718.e8 |
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Dev Cell |
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Parasympathetic innervation regulates tubulogenesis in the developing salivary gland. |
Volume: |
30 |
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J Biol Chem |
Title: |
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286 |
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González-Zorn B |
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Infect Immun |
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Bacterial and host factors implicated in nasal carriage of methicillin-resistant Staphylococcus aureus in mice. |
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J Dent Res |
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Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis. |
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Stimulation of nuclear receptor peroxisome proliferator-activated receptor-γ limits NF-κB-dependent inflammation in mouse cystic fibrosis biliary epithelium. |
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Defective FXR-FGF15 signaling and bile acid homeostasis in cystic fibrosis mice can be restored by the laxative polyethylene glycol. |
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