Type |
Details |
Score |
Publication |
First Author: |
Yu S |
Year: |
2014 |
Journal: |
EMBO J |
Title: |
TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis. |
Volume: |
33 |
Issue: |
17 |
Pages: |
1882-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miao L |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Cardiomyocyte orientation modulated by the Numb family proteins-N-cadherin axis is essential for ventricular wall morphogenesis. |
Volume: |
116 |
Issue: |
31 |
Pages: |
15560-15569 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato R |
Year: |
2018 |
Journal: |
Nat Immunol |
Title: |
Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis. |
Volume: |
19 |
Issue: |
10 |
Pages: |
1071-1082 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tyrrell BJ |
Year: |
2016 |
Journal: |
Pigment Cell Melanoma Res |
Title: |
Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour. |
Volume: |
29 |
Issue: |
5 |
Pages: |
559-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scavuzzo MA |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. |
Volume: |
9 |
Issue: |
1 |
Pages: |
3356 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aoyama M |
Year: |
2012 |
Journal: |
Dev Cell |
Title: |
Spatial restriction of bone morphogenetic protein signaling in mouse gastrula through the mVam2-dependent endocytic pathway. |
Volume: |
22 |
Issue: |
6 |
Pages: |
1163-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Castroflorio E |
Year: |
2021 |
Journal: |
Cell Mol Life Sci |
Title: |
The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour. |
Volume: |
78 |
Issue: |
7 |
Pages: |
3503-3524 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shin SW |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice. |
Volume: |
8 |
Issue: |
1 |
Pages: |
1643 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tambe Y |
Year: |
2009 |
Journal: |
Cancer Lett |
Title: |
The drs tumor suppressor is involved in the maturation process of autophagy induced by low serum. |
Volume: |
283 |
Issue: |
1 |
Pages: |
74-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu T |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
In vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkA. |
Volume: |
34 |
Issue: |
17 |
Pages: |
6098-106 |
|
•
•
•
•
•
|
Publication |
First Author: |
Safaiyan S |
Year: |
2016 |
Journal: |
Nat Neurosci |
Title: |
Age-related myelin degradation burdens the clearance function of microglia during aging. |
Volume: |
19 |
Issue: |
8 |
Pages: |
995-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mayer PR |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2. |
Volume: |
285 |
Issue: |
51 |
Pages: |
40387-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ouyang Q |
Year: |
2013 |
Journal: |
Neuron |
Title: |
Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development. |
Volume: |
80 |
Issue: |
1 |
Pages: |
97-112 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schaheen B |
Year: |
2009 |
Journal: |
J Cell Sci |
Title: |
Derlin-dependent accumulation of integral membrane proteins at cell surfaces. |
Volume: |
122 |
Issue: |
Pt 13 |
Pages: |
2228-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Urresti J |
Year: |
2016 |
Journal: |
J Biol Chem |
Title: |
Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells. |
Volume: |
291 |
Issue: |
3 |
Pages: |
1221-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsuda S |
Year: |
2013 |
Journal: |
Nat Commun |
Title: |
Stargazin regulates AMPA receptor trafficking through adaptor protein complexes during long-term depression. |
Volume: |
4 |
|
Pages: |
2759 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators, MGI curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yuasa K |
Year: |
2008 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Trafficking of cGMP-dependent protein kinase II via interaction with Rab11. |
Volume: |
374 |
Issue: |
3 |
Pages: |
522-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang DQ |
Year: |
2012 |
Journal: |
J Bone Miner Res |
Title: |
V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption. |
Volume: |
27 |
Issue: |
8 |
Pages: |
1695-707 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mochida GH |
Year: |
2009 |
Journal: |
Am J Hum Genet |
Title: |
A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly. |
Volume: |
85 |
Issue: |
6 |
Pages: |
897-902 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
1998 |
Journal: |
Hum Mol Genet |
Title: |
Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. |
Volume: |
7 |
Issue: |
12 |
Pages: |
1967-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lü J |
Year: |
2004 |
Journal: |
Dev Biol |
Title: |
Global analysis of genes differentially expressed in branching and non-branching regions of the mouse embryonic lung. |
Volume: |
273 |
Issue: |
2 |
Pages: |
418-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kerns RT |
Year: |
2005 |
Journal: |
J Neurosci |
Title: |
Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. |
Volume: |
25 |
Issue: |
9 |
Pages: |
2255-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saito F |
Year: |
2008 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Inefficient phagosome maturation in infant macrophages. |
Volume: |
375 |
Issue: |
1 |
Pages: |
113-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cerqueira DM |
Year: |
2014 |
Journal: |
Dev Biol |
Title: |
Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts. |
Volume: |
394 |
Issue: |
1 |
Pages: |
54-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zou W |
Year: |
2024 |
Journal: |
Dev Cell |
Title: |
Lysosomal dynamics regulate mammalian cortical neurogenesis. |
Volume: |
59 |
Issue: |
1 |
Pages: |
64-78.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo Y |
Year: |
2024 |
Journal: |
Signal Transduct Target Ther |
Title: |
Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. |
Volume: |
9 |
Issue: |
1 |
Pages: |
32 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7482729 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-05-22 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3570528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7482764 |
Age: |
postnatal adult |
Image: |
S5 |
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7482729 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-05-22 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3570528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7482764 |
Age: |
postnatal adult |
Image: |
S5 |
|
Specimen Label: |
KO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7482714 |
Assay Type: |
Western blot |
Annotation Date: |
2023-05-22 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3575528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7482783 |
Age: |
postnatal adult |
Image: |
4 |
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7482714 |
Assay Type: |
Western blot |
Annotation Date: |
2023-05-22 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3575528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7482783 |
Age: |
postnatal adult |
Image: |
4 |
|
Specimen Label: |
KO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6711714 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-05-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160699 |
Pattern: |
Not Specified |
Stage: |
TS09 |
Assay Id: |
MGI:6711861 |
Age: |
embryonic day 6.5 |
Image: |
3A flox/- |
|
Specimen Label: |
3A flox/- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6711714 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-05-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160699 |
Pattern: |
Not Specified |
Stage: |
TS09 |
Assay Id: |
MGI:6711861 |
Age: |
embryonic day 6.5 |
Image: |
S2A flox/- |
|
Specimen Label: |
S2A flox/- |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6711714 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-05-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:160699 |
|
Stage: |
TS09 |
Assay Id: |
MGI:6711861 |
Age: |
embryonic day 6.5 |
Image: |
S2A Sox2-cKO |
|
Specimen Label: |
S2A Sox2-cKO |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2465759 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7522947 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844417 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270519 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:4848379 |
Age: |
embryonic day 11.5 |
|
Note: |
Staining is present in the progress zone and middle limb. |
Specimen Label: |
Table S4 - E11.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3070188 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286619 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:3511227 |
Age: |
embryonic day 11.5 |
Image: |
2H |
Note: |
Expression restricted to the distal mesenchyme. |
Specimen Label: |
2H |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6711714 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-05-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160399 |
Pattern: |
Regionally restricted |
Stage: |
TS09 |
Assay Id: |
MGI:6711861 |
Age: |
embryonic day 6.5 |
Image: |
3A Ttr-cKO |
Note: |
Expression was below detectable levels in the visceral endoderm. |
Specimen Label: |
3A Ttr-cKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2465759 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7522947 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6711714 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-05-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:160519 |
|
Stage: |
TS09 |
Assay Id: |
MGI:6711861 |
Age: |
embryonic day 6.5 |
Image: |
3A Ttr-cKO |
|
Specimen Label: |
3A Ttr-cKO |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7398450 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-12-08 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:160519 |
Pattern: |
Widespread |
Stage: |
TS09 |
Assay Id: |
MGI:7398485 |
Age: |
embryonic day 6.5 |
Image: |
4a/c'/c''' |
Note: |
Expression in lysosomal membrane. Faint expression throughout all cells. |
Specimen Label: |
4a/c'/c''' |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7398450 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-12-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160519 |
Pattern: |
Regionally restricted |
Stage: |
TS09 |
Assay Id: |
MGI:7398485 |
Age: |
embryonic day 6.5 |
Image: |
4b/d'/d''' |
Note: |
Expression in large, discrete vesicles primarily in visceral endoderm. |
Specimen Label: |
4b/d'/d''' |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7398450 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-12-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160519 |
Pattern: |
Regionally restricted |
Stage: |
TS09 |
Assay Id: |
MGI:7398485 |
Age: |
embryonic day 6.5 |
Image: |
4e/e''/g |
Note: |
Higher levels of expression in proximal half of visceral endoderm thatn in distal half. |
Specimen Label: |
4e/e''/g |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7398450 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-12-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160519 |
Pattern: |
Regionally restricted |
Stage: |
TS09 |
Assay Id: |
MGI:7398485 |
Age: |
embryonic day 6.5 |
Image: |
4f/f''/h |
Note: |
Lysosomes disprersed evenly throughout visceral endoderm. No difference between proximal and distal parts. Large discrete patches non-overlapping with Lamp1 expression. |
Specimen Label: |
4f/f''/h |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160519 |
Pattern: |
Punctate |
Stage: |
TS09 |
Assay Id: |
MGI:7464737 |
Age: |
embryonic day 6.5 |
|
Note: |
Punctate expression localized to apical vacuoles in visceral endoderm. |
Specimen Label: |
1C WT sagittal |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160519 |
Pattern: |
Punctate |
Stage: |
TS09 |
Assay Id: |
MGI:7464737 |
Age: |
embryonic day 6.5 |
|
Note: |
Punctate expression localized to apical vacuoles in visceral endoderm. |
Specimen Label: |
1C WT parasagittal |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160519 |
Pattern: |
Regionally restricted |
Stage: |
TS09 |
Assay Id: |
MGI:7464737 |
Age: |
embryonic day 6.5 |
|
Note: |
Expression frequently decorated entire boundary of spherical structures. |
Specimen Label: |
1C mVam2-/- sagittal |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160519 |
Pattern: |
Regionally restricted |
Stage: |
TS09 |
Assay Id: |
MGI:7464737 |
Age: |
embryonic day 6.5 |
|
Note: |
Expression frequently decorated entire boundary of spherical structures. |
Specimen Label: |
1C mVam2-/- parasagittal |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-10-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:381337 |
Pattern: |
Not Specified |
Stage: |
TS07 |
Assay Id: |
MGI:7541126 |
Age: |
embryonic day 5.5 |
Image: |
4a/b/c |
Note: |
Appeared as dots in both the apical and basolateral cytoplasm. Often decorated the apical vacuole membranes. |
Specimen Label: |
4a/b/c |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-10-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:381337 |
Pattern: |
Not Specified |
Stage: |
TS07 |
Assay Id: |
MGI:7541126 |
Age: |
embryonic day 5.5 |
Image: |
4e/f/g |
Note: |
Increased expression. Abnormal accumulation of positive vesicles was seen. |
Specimen Label: |
4e/f/g |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
207
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Toyofuku T |
Year: |
2015 |
Journal: |
Mol Cell Biol |
Title: |
Leucine-Rich Repeat Kinase 1 Regulates Autophagy through Turning On TBC1D2-Dependent Rab7 Inactivation. |
Volume: |
35 |
Issue: |
17 |
Pages: |
3044-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Davies JP |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Cloning and mapping of human Rab7 and Rab9 cDNA sequences and identification of a Rab9 pseudogene. |
Volume: |
41 |
Issue: |
1 |
Pages: |
131-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsumoto N |
Year: |
2019 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes. |
Volume: |
510 |
Issue: |
3 |
Pages: |
421-426 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
671
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang T |
Year: |
2004 |
Journal: |
Mol Biol Cell |
Title: |
A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. |
Volume: |
15 |
Issue: |
2 |
Pages: |
815-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakanishi-Matsui M |
Year: |
2024 |
Journal: |
Biol Pharm Bull |
Title: |
Role of the Cytosolic Domain of the a3 Subunit of V-ATPase in the Interaction with Rab7 and Secretory Lysosome Trafficking in Osteoclasts. |
Volume: |
47 |
Issue: |
1 |
Pages: |
339-344 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin WJ |
Year: |
2012 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Lysosomal targeting of phafin1 mediated by Rab7 induces autophagosome formation. |
Volume: |
417 |
Issue: |
1 |
Pages: |
35-42 |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Rabring7, a novel Rab7 target protein with a RING finger motif. |
|
•
•
•
•
•
|
Publication |
First Author: |
Cabrera M |
Year: |
2014 |
Journal: |
J Cell Sci |
Title: |
The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes. |
Volume: |
127 |
Issue: |
Pt 5 |
Pages: |
1043-51 |
|
•
•
•
•
•
|
Allele |
Name: |
RAB7, member RAS oncogene family; endonuclease-mediated mutation 2, Robert W Burgess |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rab7/Rab7<+> |
Background: |
C57BL/6J-Rab7/RwbJ |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
van den Boomen DJH |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export. |
Volume: |
11 |
Issue: |
1 |
Pages: |
5559 |
|
•
•
•
•
•
|
Allele |
Name: |
RAB7, member RAS oncogene family; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Marwaha R |
Year: |
2017 |
Journal: |
J Cell Biol |
Title: |
The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes. |
Volume: |
216 |
Issue: |
4 |
Pages: |
1051-1070 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7398451 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-12-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160519 |
Pattern: |
Regionally restricted |
Stage: |
TS09 |
Assay Id: |
MGI:7398486 |
Age: |
embryonic day 6.5 |
Image: |
4f/f'''/h |
Note: |
Late endosomes dispersed evenly throughout visceral endoderm with no difference between proximal and distal parts. Large discrete patches non-overlapping with Rab7 expression. |
Specimen Label: |
4f/f'''/h |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Verhoeven K |
Year: |
2003 |
Journal: |
Am J Hum Genet |
Title: |
Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy. |
Volume: |
72 |
Issue: |
3 |
Pages: |
722-7 |
|
•
•
•
•
•
|
Allele |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Zhenming Xu |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Inserted expressed sequence |
|
•
•
•
•
•
|
Publication |
First Author: |
Peralta ER |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Differential effects of TBC1D15 and mammalian Vps39 on Rab7 activation state, lysosomal morphology, and growth factor dependence. |
Volume: |
285 |
Issue: |
22 |
Pages: |
16814-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Numrich J |
Year: |
2015 |
Journal: |
J Cell Sci |
Title: |
The I-BAR protein Ivy1 is an effector of the Rab7 GTPase Ypt7 involved in vacuole membrane homeostasis. |
Volume: |
128 |
Issue: |
13 |
Pages: |
2278-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pankiv S |
Year: |
2010 |
Journal: |
J Cell Biol |
Title: |
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. |
Volume: |
188 |
Issue: |
2 |
Pages: |
253-69 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, targeted mutation |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
141
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
134
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Rab interacting lysosomal protein (RILP) contains a domain which contains two coiled-coil regions and is found mainly in the cytosol. RILP is recruited onto late endosomal and lysosomal membranes by Rab7 and acts as a downstream effector of Rab7 []. This recruitment process is important for phagosome maturation and fusion with late endosomes and lysosomes. |
|
•
•
•
•
•
|