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Search results 1 to 1 out of 1 for Kif20a

Category restricted to ProteinDomain (x)

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Categories

Category: ProteinDomain
Type Details Score
Protein Domain
Type: Family
Description: Kinesin-like protein KIF20A was first identified as a binding partner for the rab6 GTPase involved in protein transport at the Golgi apparatus []. It was later found to be a mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. It is phosphorylated by PLK1 at Ser-528 during mitosis, creating a docking site for PLK1 and recruiting PLK1 at central spindle. It contains a kinesin-motor domain and has a microtubule plus end-directed motility [].