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Search results 101 to 200 out of 230 for Smg1

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Type Details Score
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Protein
Q8BKX6-2
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
Q8BKX6-3
Organism: Mus musculus/domesticus
Length: 433  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase SMG1
Type: chain
End: 3658
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Protein
J3QPA7
Organism: Mus musculus/domesticus
Length: 335  
Fragment?: true
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Protein
J3QMR1
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: true
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Protein
J3QQ22
Organism: Mus musculus/domesticus
Length: 59  
Fragment?: true
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Gene
108703118 | smg1.S
Type: gene
Organism: frog, African clawed
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Gene
779188 | smg1.L
Type: gene
Organism: frog, African clawed
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Allele
Smg1<Gt(XI470)Byg> | MGI:4128189
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap XI470, BayGenomics
Allele Type: Gene trapped
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Allele
Smg1<Gt(RRT449)Byg> | MGI:4338581
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap RRT449, BayGenomics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
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Allele
Smg1<Gt(XH737)Byg> | MGI:4126529
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap XH737, BayGenomics
Allele Type: Gene trapped
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Allele
Smg1<Gt(37v-50)Yais> | MGI:4831310
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap 37v-50, Yasumasa Ishida
Allele Type: Gene trapped
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Allele
Smg1<Gt(XB150)Byg> | MGI:4123780
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap XB150, BayGenomics
Allele Type: Gene trapped
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Allele
Smg1<Gt(OST308135)Lex> | MGI:4273904
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap OST308135, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Smg1<Gt(OST78758)Lex> | MGI:4175872
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap OST78758, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Smg1<Gt(OST391154)Lex> | MGI:4303529
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap OST391154, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Smg1<Gt(OST7459)Lex> | MGI:4135683
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap OST7459, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Smg1<Gt(XI478)Byg> | MGI:4128187
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap XI478, BayGenomics
Allele Type: Gene trapped
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Allele
Smg1<+> | MGI:3822466
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; wild type
Allele Type: Not Specified
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Allele
Smg1<Gt(OST439673)Lex> | MGI:4317814
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap OST439673, Lexicon Genetics
Allele Type: Gene trapped
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Protein
D3Z719
Organism: Mus musculus/domesticus
Length: 210  
Fragment?: true
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Protein
F6YIT4
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: true
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Protein Domain
IPR039177 | SMG9
Type: Family
Description: Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that detects and degrades mRNAs containing premature translation termination codons. Protein SMG9 is a component of the SMG1C protein kinase complex (along with SMG1 and SMG8) which is recruited to stalled ribosomes. SMG8 and SMG9 suppress SMG1 kinase activity in the isolated SMG1 complex [].
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Strain
MGI:5495263 | B6.129P2-Smg1<Gt(RRT449)Byg>
Attribute String: congenic, gene trap, mutant strain
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Allele
Smg1<tm1b(EUCOMM)Hmgu> | MGI:5692718
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:6260876 | C57BL/6N-Smg1<tm1b(EUCOMM)Hmgu>/Wtsi
Attribute String: coisogenic, targeted mutation
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Strain
MGI:7381017 | C57BL/6N-Smg1<tm1b(EUCOMM)Hmgu>/WtsiH
Attribute String: coisogenic, mutant strain, targeted mutation
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Allele
Smg1<Gt(IST10762D2)Tigm> | MGI:3966113
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST10762D2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(A057E04)Wrst> | MGI:4335519
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap A057E04, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST14925B6)Tigm> | MGI:5268709
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST14925B6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(519B10)Cmhd> | MGI:4957319
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap 519B10, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Smg1<Gt(183B8)Cmhd> | MGI:4969584
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap 183B8, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST11538E8)Tigm> | MGI:4053889
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST11538E8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(EUCJ00133a05)Hmgu> | MGI:4869920
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap EUCJ00133a05, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Smg1<em1Gpt> | MGI:7306517
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6769504 | C57BL/6JGpt-Smg1<em1Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Smg1<Gt(IST10062C7)Tigm> | MGI:5142554
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST10062C7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST14926C8)Tigm> | MGI:5268807
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST14926C8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST15000A5)Tigm> | MGI:5274378
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST15000A5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST12509B1)Tigm> | MGI:4072432
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST12509B1, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(AR0550)Wtsi> | MGI:4346580
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap AR0550, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Smg1<tm1a(EUCOMM)Hmgu> | MGI:5497170
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Strain
MGI:6122782 | C57BL/6N-A<tm1Brd> Smg1<tm1a(EUCOMM)Hmgu>/WtsiBiat
Attribute String: mutant strain, coisogenic, targeted mutation
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Allele
Smg1<Gt(IST14779F2)Tigm> | MGI:5258790
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST14779F2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST13301D3)Tigm> | MGI:5162216
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST13301D3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST13519G9)Tigm> | MGI:5171754
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST13519G9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST11568E4)Tigm> | MGI:4058539
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST11568E4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(407A8)Cmhd> | MGI:4954314
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap 407A8, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST14857G10)Tigm> | MGI:5269192
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST14857G10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<tm1a(NCOM)Mfgc> | MGI:5766030
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; targeted mutation 1a, Mammalian Functional Genomics Centre
Allele Type: Targeted
Attribute String: Conditional ready, Reporter
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Allele
Smg1<Gt(IST13159G3)Tigm> | MGI:5157251
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST13159G3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST14765C5)Tigm> | MGI:5257269
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST14765C5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST15050G6)Tigm> | MGI:5279777
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST15050G6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(A071A03)Wrst> | MGI:3859231
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap A071A03, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Smg1<Gt(A020A02)Wrst> | MGI:4123225
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap A020A02, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Smg1<Gt(EUCE0199h08)Hmgu> | MGI:4368200
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap EUCE0199h08, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Smg1<Gt(407B8)Cmhd> | MGI:4954305
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap 407B8, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST14969E1)Tigm> | MGI:5272670
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST14969E1, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<tm1a(EUCOMM)Wtsi> | MGI:5472702
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Smg1<Gt(IST15051F7)Tigm> | MGI:5279840
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST15051F7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(408B8)Cmhd> | MGI:4953843
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap 408B8, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Smg1<tm2a(EUCOMM)Wtsi> | MGI:5511988
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; targeted mutation 2a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Smg1<Gt(IST13620G2)Tigm> | MGI:5177576
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST13620G2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST14767F3)Tigm> | MGI:5261989
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST14767F3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST15075E12)Tigm> | MGI:5280070
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST15075E12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST12506H10)Tigm> | MGI:4075102
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST12506H10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST14848H7)Tigm> | MGI:5262864
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST14848H7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(AG0297)Wtsi> | MGI:3876748
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap AG0297, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
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Allele
Smg1<Gt(IST12360D3)Tigm> | MGI:4070457
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST12360D3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(IST14869E8)Tigm> | MGI:5265544
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap IST14869E8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Smg1<Gt(E215E05)Wrst> | MGI:3918912
 
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase; gene trap E215E05, German Gene Trap Consortium
Allele Type: Gene trapped
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Genotype
Genotype
Symbol: Smg1/Smg1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smg1/Smg1
Background: B6.129P2-Smg1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smg1/Smg1
Background: C57BL/6N-Smg1/Wtsi
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smg1/Smg1<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smg1/Smg1<+>
Background: C57BL/6N-Smg1/Wtsi
Zygosity: ht
Has Mutant Allele: true
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Publication
19417104 | -
First Author: Yamashita A
Year: 2009
Journal: Genes Dev
Title: SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.
Volume: 23
Issue: 9
Pages: 1091-105
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Publication
11544179 | -
First Author: Yamashita A
Year: 2001
Journal: Genes Dev
Title: Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay.
Volume: 15
Issue: 17
Pages: 2215-28
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Publication
21911475 | -
First Author: Brown JA
Year: 2011
Journal: Mol Cell Biol
Title: A novel role for hSMG-1 in stress granule formation.
Volume: 31
Issue: 22
Pages: 4417-29
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Protein Domain
IPR035175 | SMG1_N
Type: Domain
Description: This entry represents the N-terminal domain of SMG1, which is a member of the phosphoinositide 3 kinase-like kinase (PIKK) family. SMG1 associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay []. It also plays an important role in genotoxic stress responses to DNA damage [].
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Allele
Del(7Slx1b-Sept1)4Aam | MGI:4462822
Name: deletion, Chr 7, Alea A Mills 4
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Dp(7Slx1b-Sept1)5Aam | MGI:4462823
 
Name: duplication, Chr 7, Alea A Mills 5
Allele Type: Targeted
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Protein
Q9DB90
Organism: Mus musculus/domesticus
Length: 520  
Fragment?: false
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Strain
MGI:5295567 | B6129S-Del(7Slx1b-Sept1)4Aam/J
Attribute String: mutant stock, targeted mutation, deletion
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Strain
MGI:5317214 | B6.129S7-Del(7Slx1b-Sept1)4Aam/J
Attribute String: congenic, mutant strain, targeted mutation, deletion
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Publication
25698753 | J:219859
First Author: Pucilowska J
Year: 2015
Journal: J Neurosci
Title: The 16p11.2 deletion mouse model of autism exhibits altered cortical progenitor proliferation and brain cytoarchitecture linked to the ERK MAPK pathway.
Volume: 35
Issue: 7
Pages: 3190-200
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Publication
29934348 | J:301971
First Author: Pucilowska J
Year: 2018
Journal: J Neurosci
Title: Pharmacological Inhibition of ERK Signaling Rescues Pathophysiology and Behavioral Phenotype Associated with 16p11.2 Chromosomal Deletion in Mice.
Volume: 38
Issue: 30
Pages: 6640-6652
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Publication
29853627 | J:263550
First Author: Wang W
Year: 2018
Journal: J Neurosci
Title: Chemogenetic Activation of Prefrontal Cortex Rescues Synaptic and Behavioral Deficits in a Mouse Model of 16p11.2 Deletion Syndrome.
Volume: 38
Issue: 26
Pages: 5939-5948
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Publication
32704009 | J:294217
First Author: Mitchell EJ
Year: 2020
Journal: Sci Rep
Title: Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model: a central role for gene-environment interactions.
Volume: 10
Issue: 1
Pages: 12303
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Publication
28948999 | J:257347
First Author: Panzini CM
Year: 2017
Journal: J Neurochem
Title: 16p11.2 deletion syndrome mice perseverate with active coping response to acute stress - rescue by blocking 5-HT2A receptors.
Volume: 143
Issue: 6
Pages: 708-721
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Publication
25581360 | J:219585
First Author: Tian D
Year: 2015
Journal: Nat Neurosci
Title: Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion.
Volume: 18
Issue: 2
Pages: 182-4
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Genotype
Genotype
Symbol: Del(7Slx1b-Sept1)4Aam/+
Background: involves: 129S7/SvEvBrd * C57BL/6N
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(7Slx1b-Sept1)4Aam/+
Background: involves: 129S7/SvEvBrd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(7Slx1b-Sept1)4Aam/?
Background: B6129S-Del(7Slx1b-Sept1)4Aam/J
Zygosity: ot
Has Mutant Allele: true
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Strain
MGI:5295572 | B6129S-Dp(7Slx1b-Sept1)5Aam/J
Attribute String: duplication, mutant stock, targeted mutation, deletion
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Strain
MGI:5317428 | B6.127S7-Dp(7Slx1b-Sept1)5Aam/J
Attribute String: targeted mutation, duplication, mutant strain, congenic
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