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Search results 501 to 590 out of 590 for Agrp

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Hits by Strain

Hits by Category

Type Details Score
Genotype
Genotype
Symbol: Agrp/Agrp<+> Slc32a1/Slc32a1
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Agrp/Agrp<+> Lepr/Lepr
Background: involves: 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rock1/Rock1 Agrp/Agrp<+>
Background: involves: 129S4/SvJaeSor * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tbx3/Tbx3 Agrp/Agrp<+>
Background: involves: C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nampt/Nampt Agrp/Agrp<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6JBomTac
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Agrp/Agrp<+> Slc32a1/Slc32a1
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Agrp-cre)1Gsb/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
16098827 | J:129837
First Author: Ren D
Year: 2005
Journal: Cell Metab
Title: Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice.
Volume: 2
Issue: 2
Pages: 95-104
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Publication
21195353 | J:169476
First Author: Wang H
Year: 2011
Journal: Cell Metab
Title: Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity.
Volume: 13
Issue: 1
Pages: 105-13
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Publication
30067966 | J:270674
First Author: Ravussin A
Year: 2018
Journal: Cell Rep
Title: Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity.
Volume: 24
Issue: 5
Pages: 1085-1092.e6
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Publication
31730854 | J:291579
First Author: Bai L
Year: 2019
Journal: Cell
Title: Genetic Identification of Vagal Sensory Neurons That Control Feeding.
Volume: 179
Issue: 5
Pages: 1129-1143.e23
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Publication
18460329 | J:136219
First Author: Anderson KA
Year: 2008
Journal: Cell Metab
Title: Hypothalamic CaMKK2 contributes to the regulation of energy balance.
Volume: 7
Issue: 5
Pages: 377-88
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Publication
24199146 | J:221319
First Author: Schneeberger M
Year: 2012
Journal: Mol Metab
Title: Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to pituitary dysfunction, neurodegeneration and development of obesity.
Volume: 2
Issue: 2
Pages: 74-85
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Publication
21642978 | J:173466
First Author: Purkayastha S
Year: 2011
Journal: Nat Med
Title: Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB.
Volume: 17
Issue: 7
Pages: 883-7
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Genotype
Genotype
Symbol: A/a Agrp/Agrp<+>
Background: involves: 129S4/SvJaeSor * KK/Upj
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Agrp/Agrp<+> Lepr/Lepr Tg(Pomc1-hrGFP)1Lowl/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Agrp/Agrp<+> Slc32a1/Slc32a1 Tg(Pomc1-hrGFP)1Lowl/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Agrp/Agrp<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Agrp/Agrp<+> Tg(CAG-Bgeo/GFP)21Lbe/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Agrp/Agrp<+> Tg(Npy-hrGFP)1Lowl/?
Background: involves: 129S6/SvEvTac * FVB
Zygosity: cn
Has Mutant Allele: true
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Publication
9892020 | J:51862
First Author: Yang YK
Year: 1999
Journal: Mol Endocrinol
Title: Characterization of Agouti-related protein binding to melanocortin receptors.
Volume: 13
Issue: 1
Pages: 148-55
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Publication
23897430 | J:205020
First Author: Kim SG
Year: 2013
Journal: Mol Cell Biol
Title: Control of energy balance by hypothalamic gene circuitry involving two nuclear receptors, neuron-derived orphan receptor 1 and glucocorticoid receptor.
Volume: 33
Issue: 19
Pages: 3826-34
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Publication
23307790 | J:195433
First Author: Briggs DI
Year: 2013
Journal: Endocrinology
Title: Calorie-restricted weight loss reverses high-fat diet-induced ghrelin resistance, which contributes to rebound weight gain in a ghrelin-dependent manner.
Volume: 154
Issue: 2
Pages: 709-17
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Publication
16367788 | J:104309
First Author: Fetissov SO
Year: 2005
Journal: Eur J Neurosci
Title: Alterations of arcuate nucleus neuropeptidergic development in contactin-deficient mice: comparison with anorexia and food-deprived mice.
Volume: 22
Issue: 12
Pages: 3217-28
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Publication
36180454 | J:330249
First Author: Strembitska A
Year: 2022
Journal: Nat Commun
Title: Lipid biosynthesis enzyme Agpat5 in AgRP-neurons is required for insulin-induced hypoglycemia sensing and glucagon secretion.
Volume: 13
Issue: 1
Pages: 5761
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Publication
24053666 | J:202687
 
First Author: Byerly MS
Year: 2013
Journal: BMC Physiol
Title: Estrogen-related receptor β deficiency alters body composition and response to restraint stress.
Volume: 13
Pages: 10
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Publication
23493572 | J:208667
First Author: Ramírez S
Year: 2013
Journal: Diabetes
Title: Hypothalamic ceramide levels regulated by CPT1C mediate the orexigenic effect of ghrelin.
Volume: 62
Issue: 7
Pages: 2329-37
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Publication
21963822 | J:215868
First Author: Verhulst PJ
Year: 2012
Journal: Regul Pept
Title: Role of the AMP-activated protein kinase (AMPK) signaling pathway in the orexigenic effects of endogenous ghrelin.
Volume: 173
Issue: 1-3
Pages: 27-35
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Publication
20967882 | J:167571
First Author: Nilsson IA
Year: 2011
Journal: Glia
Title: Evidence of hypothalamic degeneration in the anorectic anx/anx mouse.
Volume: 59
Issue: 1
Pages: 45-57
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Publication
18403487 | J:145370
First Author: Gong L
Year: 2008
Journal: Endocrinology
Title: Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis.
Volume: 149
Issue: 7
Pages: 3346-54
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Publication
33296280 | J:301998
     
First Author: Gasparini S
Year: 2020
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Pre-locus coeruleus neurons in rat and mouse.
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Publication
31245789 | J:286156
First Author: Mirzadeh Z
Year: 2019
Journal: Nat Metab
Title: Perineuronal Net Formation during the Critical Period for Neuronal Maturation in the Hypothalamic Arcuate Nucleus.
Volume: 1
Issue: 2
Pages: 212-221
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Publication
29522093 | J:260503
First Author: Pan W
Year: 2018
Journal: Endocrinology
Title: Essential Role for Hypothalamic Calcitonin Receptor‒Expressing Neurons in the Control of Food Intake by Leptin.
Volume: 159
Issue: 4
Pages: 1860-1872
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Publication
32895383 | J:297247
First Author: Bentsen MA
Year: 2020
Journal: Nat Commun
Title: Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission.
Volume: 11
Issue: 1
Pages: 4458
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Publication
29467172 | J:262098
First Author: Lutz TA
Year: 2018
Journal: Diabetes
Title: Amylin Selectively Signals Onto POMC Neurons in the Arcuate Nucleus of the Hypothalamus.
Volume: 67
Issue: 5
Pages: 805-817
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Publication
20923696 | J:170180
First Author: Zheng Q
Year: 2010
Journal: Neuroscience
Title: Enhanced anorexigenic signaling in lean obesity resistant syndecan-3 null mice.
Volume: 171
Issue: 4
Pages: 1032-40
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Publication
27911598 | J:245943
First Author: Wu Z
Year: 2017
Journal: Endocrinology
Title: Type 3 Deiodinase Role on Central Thyroid Hormone Action Affects the Leptin-Melanocortin System and Circadian Activity.
Volume: 158
Issue: 2
Pages: 419-430
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Publication
26610903 | J:228734
 
First Author: Ma S
Year: 2016
Journal: Neurosci Lett
Title: Transgenic n-3 PUFAs enrichment leads to weight loss via modulating neuropeptides in hypothalamus.
Volume: 611
Pages: 28-32
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Publication
17065347 | J:116549
First Author: Patel HR
Year: 2006
Journal: Diabetes
Title: Neuropeptide Y deficiency attenuates responses to fasting and high-fat diet in obesity-prone mice.
Volume: 55
Issue: 11
Pages: 3091-8
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Publication
11796511 | J:74978
First Author: Tschöp M
Year: 2002
Journal: Endocrinology
Title: GH-releasing peptide-2 increases fat mass in mice lacking NPY: indication for a crucial mediating role of hypothalamic agouti-related protein.
Volume: 143
Issue: 2
Pages: 558-68
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Publication
30224492 | J:265913
First Author: Wei Q
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Uneven balance of power between hypothalamic peptidergic neurons in the control of feeding.
Volume: 115
Issue: 40
Pages: E9489-E9498
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Publication
16174655 | J:105686
First Author: Egecioglu E
Year: 2006
Journal: Am J Physiol Endocrinol Metab
Title: Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity, and hypolipidemia in mice.
Volume: 290
Issue: 2
Pages: E317-25
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Publication
17334640 | J:125256
First Author: Asakawa A
Year: 2007
Journal: Int J Mol Med
Title: Ins2Akita mice exhibit hyperphagia and anxiety behavior via the melanocortin system.
Volume: 19
Issue: 4
Pages: 649-52
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Publication
11882520 | J:75872
First Author: Tsuruta Y
Year: 2002
Journal: Am J Physiol Endocrinol Metab
Title: Hyperleptinemia in A(y)/a mice upregulates arcuate cocaine- and amphetamine-regulated transcript expression.
Volume: 282
Issue: 4
Pages: E967-73
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Publication
14559977 | J:125996
First Author: Arens J
Year: 2003
Journal: Physiol Genomics
Title: Age-dependent hypothalamic expression of neuropeptides in wild-type and melanocortin-4 receptor-deficient mice.
Volume: 16
Issue: 1
Pages: 38-46
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Publication
27941249 | J:239842
First Author: Burnett LC
Year: 2017
Journal: J Clin Invest
Title: Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome.
Volume: 127
Issue: 1
Pages: 293-305
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Publication
17374695 | J:126508
First Author: Lee M
Year: 2007
Journal: Am J Physiol Endocrinol Metab
Title: Transgenic MSH overexpression attenuates the metabolic effects of a high-fat diet.
Volume: 293
Issue: 1
Pages: E121-31
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Publication
12072562 | J:77345
First Author: Sainsbury A
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice.
Volume: 99
Issue: 13
Pages: 8938-43
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Publication
28076448 | J:266831
First Author: Decourtye L
Year: 2017
Journal: PLoS One
Title: IGF-1 Induces GHRH Neuronal Axon Elongation during Early Postnatal Life in Mice.
Volume: 12
Issue: 1
Pages: e0170083
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Publication
16046291 | J:136937
First Author: Coll AP
Year: 2005
Journal: Diabetes
Title: Proopiomelanocortin-deficient mice are hypersensitive to the adverse metabolic effects of glucocorticoids.
Volume: 54
Issue: 8
Pages: 2269-76
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Publication
35470501 | J:337186
First Author: Naser W
Year: 2022
Journal: FASEB J
Title: Cytokine-inducible SH2 domain containing protein contributes to regulation of adiposity, food intake, and glucose metabolism.
Volume: 36
Issue: 5
Pages: e22320
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Publication
19270710 | J:149375
First Author: Cao L
Year: 2009
Journal: Nat Med
Title: Molecular therapy of obesity and diabetes by a physiological autoregulatory approach.
Volume: 15
Issue: 4
Pages: 447-54
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Publication
17909095 | J:132419
First Author: Tolle V
Year: 2008
Journal: Diabetes
Title: In vivo evidence for inverse agonism of Agouti-related peptide in the central nervous system of proopiomelanocortin-deficient mice.
Volume: 57
Issue: 1
Pages: 86-94
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Publication
20428232 | J:160135
First Author: Tanegashima K
Year: 2010
Journal: PLoS One
Title: CXCL14 deficiency in mice attenuates obesity and inhibits feeding behavior in a novel environment.
Volume: 5
Issue: 4
Pages: e10321
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Publication
30500912 | J:269695
First Author: Loganathan N
Year: 2019
Journal: Endocrinology
Title: Bisphenol A Alters Bmal1, Per2, and Rev-Erba mRNA and Requires Bmal1 to Increase Neuropeptide Y Expression in Hypothalamic Neurons.
Volume: 160
Issue: 1
Pages: 181-192
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Publication
24996410 | J:323636
First Author: Torres-Andrade R
Year: 2014
Journal: Exp Physiol
Title: The increase in body weight induced by lack of methyl CpG binding protein-2 is associated with altered leptin signalling in the hypothalamus.
Volume: 99
Issue: 9
Pages: 1229-40
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Publication
32114021 | J:296866
 
First Author: Clemenzi MN
Year: 2020
Journal: Mol Cell Endocrinol
Title: Analysis of Western diet, palmitate and BMAL1 regulation of neuropeptide Y expression in the murine hypothalamus and BMAL1 knockout cell models.
Volume: 507
Pages: 110773
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Publication
11756683 | J:73683
First Author: Shimokawa T
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides.
Volume: 99
Issue: 1
Pages: 66-71
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Publication
11001766 | J:65222
First Author: Ziotopoulou M
Year: 2000
Journal: Am J Physiol Endocrinol Metab
Title: Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice.
Volume: 279
Issue: 4
Pages: E838-45
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Publication
9893984 | J:52292
First Author: Tota MR
Year: 1999
Journal: Biochemistry
Title: Molecular interaction of Agouti protein and Agouti-related protein with human melanocortin receptors.
Volume: 38
Issue: 3
Pages: 897-904
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Publication
16959942 | J:135854
First Author: Getting SJ
Year: 2006
Journal: Mol Pharmacol
Title: [D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse).
Volume: 70
Issue: 6
Pages: 1850-5
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Publication
19616032 | J:153149
First Author: Yu Y
Year: 2009
Journal: Behav Brain Res
Title: Obese reversal by a chronic energy restricted diet leaves an increased Arc NPY/AgRP, but no alteration in POMC/CART, mRNA expression in diet-induced obese mice.
Volume: 205
Issue: 1
Pages: 50-6
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Publication
31530579 | J:282299
First Author: Al-Massadi O
Year: 2019
Journal: Diabetes
Title: MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance.
Volume: 68
Issue: 12
Pages: 2210-2222
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Publication
31340540 | J:290754
 
First Author: Torres DJ
Year: 2019
Journal: Nutrients
Title: Agrp-Specific Ablation of Scly Protects against Diet-Induced Obesity and Leptin Resistance.
Volume: 11
Issue: 7
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Publication
32468663 | J:298083
First Author: Hu Y
Year: 2020
Journal: Genesis
Title: Development and characterization of an Otp conditional loss of function allele.
Volume: 58
Issue: 9
Pages: e23370
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Publication
33382813 | J:299512
First Author: Na ES
Year: 2020
Journal: PLoS One
Title: Decreased sensitivity to the anorectic effects of leptin in mice that lack a Pomc-specific neural enhancer.
Volume: 15
Issue: 12
Pages: e0244793
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Publication
23246158 | J:309836
First Author: Li H
Year: 2013
Journal: J Nutr Biochem
Title: A role for inducible 6-phosphofructo-2-kinase in the control of neuronal glycolysis.
Volume: 24
Issue: 6
Pages: 1153-8
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Publication
33715219 | J:339833
First Author: Xiang J
Year: 2021
Journal: FASEB J
Title: Elevated HB-EGF expression in neural stem cells causes middle age obesity by suppressing Hypocretin/Orexin expression.
Volume: 35
Issue: 4
Pages: e21345
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Publication
37495689 | J:340496
First Author: Douglass AM
Year: 2023
Journal: Nature
Title: Neural basis for fasting activation of the hypothalamic-pituitary-adrenal axis.
Volume: 620
Issue: 7972
Pages: 154-162
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Genotype
Genotype
Symbol: Agrp/Agrp<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdyn-EGFP)BD193Gsat/?
Background: involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/NTac
Zygosity: cn
Has Mutant Allele: true
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Publication
21151569 | J:167736
First Author: Hong CJ
Year: 2010
Journal: PLoS One
Title: ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinemia caused by a novel mutation in leptin.
Volume: 5
Issue: 12
Pages: e15333
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Publication
26203139 | J:225811
First Author: Kim ER
Year: 2015
Journal: J Neurosci
Title: Hypothalamic Non-AgRP, Non-POMC GABAergic Neurons Are Required for Postweaning Feeding and NPY Hyperphagia.
Volume: 35
Issue: 29
Pages: 10440-50
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Publication
33549847 | J:317106
 
First Author: Hundahl C
Year: 2021
Journal: Mol Metab
Title: Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis.
Volume: 47
Pages: 101174
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Publication
18657539 | J:141985
First Author: Verhulst PJ
Year: 2008
Journal: Gastroenterology
Title: Role of ghrelin in the relationship between hyperphagia and accelerated gastric emptying in diabetic mice.
Volume: 135
Issue: 4
Pages: 1267-76
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Publication
28547758 | J:247911
First Author: Chen SR
Year: 2017
Journal: J Neurochem
Title: Ghrelin receptors mediate ghrelin-induced excitation of agouti-related protein/neuropeptide Y but not pro-opiomelanocortin neurons.
Volume: 142
Issue: 4
Pages: 512-520
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Publication
21906594 | J:178372
First Author: Büdefeld T
Year: 2011
Journal: Exp Neurol
Title: Altered position of cell bodies and fibers in the ventromedial region in SF-1 knockout mice.
Volume: 232
Issue: 2
Pages: 176-84
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Publication
33157254 | J:317169
 
First Author: Werdermann M
Year: 2021
Journal: Mol Metab
Title: Insulin and obesity transform hypothalamic-pituitary-adrenal axis stemness and function in a hyperactive state.
Volume: 43
Pages: 101112
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Publication
28627418 | J:244291
 
First Author: Schriever SC
Year: 2017
Journal: Neuroscience
Title: Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency.
Volume: 357
Pages: 241-254
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Publication
9450927 | J:45801
First Author: Ollmann MM
Year: 1998
Journal: Genes Dev
Title: Interaction of Agouti protein with the melanocortin 1 receptor in vitro and in vivo.
Volume: 12
Issue: 3
Pages: 316-30
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Publication
10509609 | J:59756
First Author: Moussa NM
Year: 1999
Journal: Obes Res
Title: The yellow mouse obesity syndrome and mechanisms of agouti-induced obesity.
Volume: 7
Issue: 5
Pages: 506-14
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Publication
37635967 | J:339690
 
First Author: Norberto S
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: CLK2 in GABAergic neurons is critical in regulating energy balance and anxiety-like behavior in a gender-specific fashion.
Volume: 14
Pages: 1172835
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Publication
16763061 | J:129642
First Author: Densmore VS
Year: 2006
Journal: Endocrinology
Title: 11 beta-hydroxysteroid dehydrogenase type 1 induction in the arcuate nucleus by high-fat feeding: A novel constraint to hyperphagia?
Volume: 147
Issue: 9
Pages: 4486-95
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Publication
24015235 | J:206409
First Author: Pazos P
Year: 2013
Journal: PLoS One
Title: Interleukin 6 deficiency modulates the hypothalamic expression of energy balance regulating peptides during pregnancy in mice.
Volume: 8
Issue: 8
Pages: e72339
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Publication
11078456 | J:65484
First Author: Ziotopoulou M
Year: 2000
Journal: Diabetes
Title: Unlike leptin, ciliary neurotrophic factor does not reverse the starvation-induced changes of serum corticosterone and hypothalamic neuropeptide levels but induces expression of hypothalamic inhibitors of leptin signaling.
Volume: 49
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First Author: Brown RE
Year: 2009
Journal: Brain Res
Title: Resistin differentially modulates neuropeptide gene expression and AMP-activated protein kinase activity in N-1 hypothalamic neurons.
Volume: 1294
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First Author: Kuhajda FP
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity.
Volume: 301
Issue: 1
Pages: R116-30
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First Author: Schmid T
Year: 2013
Journal: J Neurosci
Title: Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity.
Volume: 33
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Pages: 10459-70
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Year: 2002
Journal: Diabetes
Title: Attenuation of diabetic hyperphagia in neuropeptide Y--deficient mice.
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Year: 2017
Journal: J Physiol
Title: Caloric restriction selectively reduces the GABAergic phenotype of mouse hypothalamic proopiomelanocortin neurons.
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First Author: Zheng R
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Deficiency of the RIIβ subunit of PKA affects locomotor activity and energy homeostasis in distinct neuronal populations.
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