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Search results 101 to 200 out of 607 for Tet2

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Type Details Score
Publication
First Author: Jing CB
Year: 2020
Journal: Leukemia
Title: Synthetic lethal targeting of TET2-mutant hematopoietic stem and progenitor cells (HSPCs) with TOP1-targeted drugs and PARP1 inhibitors.
Volume: 34
Issue: 11
Pages: 2992-3006
Publication
First Author: Ko M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice.
Volume: 108
Issue: 35
Pages: 14566-71
Publication
First Author: Yan H
Year: 2020
Journal: Clin Epigenetics
Title: Ten-eleven translocation methyl-cytosine dioxygenase 2 deficiency exacerbates renal ischemia-reperfusion injury.
Volume: 12
Issue: 1
Pages: 98
Publication
First Author: Fujisawa M
Year: 2022
Journal: Blood
Title: Clonal germinal center B cells function as a niche for T-cell lymphoma.
Volume: 140
Issue: 18
Pages: 1937-1950
Publication  
First Author: Zeng H
Year: 2019
Journal: Cancer Lett
Title: Antibiotic treatment ameliorates Ten-eleven translocation 2 (TET2) loss-of-function associated hematological malignancies.
Volume: 467
Pages: 1-8
Publication
First Author: Peng J
Year: 2016
Journal: Oncotarget
Title: Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE-/- mice.
Volume: 7
Issue: 47
Pages: 76423-76436
Publication
First Author: Cortes JR
Year: 2018
Journal: Cancer Cell
Title: RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis.
Volume: 33
Issue: 2
Pages: 259-273.e7
Publication
First Author: Moon CS
Year: 2021
Journal: Nat Cancer
Title: FYN-TRAF3IP2 induces NF-κB signaling-driven peripheral T cell lymphoma.
Volume: 2
Issue: 1
Pages: 98-113
Publication
First Author: Viaud M
Year: 2020
Journal: Cell Rep
Title: ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.
Volume: 30
Issue: 10
Pages: 3397-3410.e5
Publication
First Author: Cheng Y
Year: 2018
Journal: Cell Rep
Title: Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice.
Volume: 25
Issue: 11
Pages: 3194-3203.e4
Publication
First Author: Shih AH
Year: 2015
Journal: Cancer Cell
Title: Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.
Volume: 27
Issue: 4
Pages: 502-15
Publication
First Author: Obeng EA
Year: 2016
Journal: Cancer Cell
Title: Physiologic Expression of Sf3b1(K700E) Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation.
Volume: 30
Issue: 3
Pages: 404-417
Publication
First Author: Xue JH
Year: 2016
Journal: J Biol Chem
Title: Uracil-DNA Glycosylase UNG Promotes Tet-mediated DNA Demethylation.
Volume: 291
Issue: 2
Pages: 731-8
Publication
First Author: Nguyen TB
Year: 2020
Journal: Cancer Res
Title: Dasatinib Is an Effective Treatment for Angioimmunoblastic T-cell Lymphoma.
Volume: 80
Issue: 9
Pages: 1875-1884
Publication
First Author: Zhang H
Year: 2019
Journal: Nat Commun
Title: Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms.
Volume: 10
Issue: 1
Pages: 244
Publication  
First Author: Balasubramani A
Year: 2015
Journal: Nat Commun
Title: Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex.
Volume: 6
Pages: 7307
Publication
First Author: Sardina JL
Year: 2018
Journal: Cell Stem Cell
Title: Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate.
Volume: 23
Issue: 5
Pages: 727-741.e9
Publication
First Author: Huang G
Year: 2020
Journal: iScience
Title: Tet1 Deficiency Leads to Premature Reproductive Aging by Reducing Spermatogonia Stem Cells and Germ Cell Differentiation.
Volume: 23
Issue: 3
Pages: 100908
Publication  
First Author: Li X
Year: 2017
Journal: Nat Commun
Title: Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis.
Volume: 8
Pages: 15903
Publication
First Author: Zeng Z
Year: 2021
Journal: Circulation
Title: Circular RNA CircMAP3K5 Acts as a MicroRNA-22-3p Sponge to Promote Resolution of Intimal Hyperplasia Via TET2-Mediated Smooth Muscle Cell Differentiation.
Volume: 143
Issue: 4
Pages: 354-371
Publication
First Author: Li L
Year: 2021
Journal: J Neurochem
Title: Role of Ten eleven translocation-2 (Tet2) in modulating neuronal morphology and cognition in a mouse model of Alzheimer's disease.
Volume: 157
Issue: 4
Pages: 993-1012
Publication
First Author: Wang L
Year: 2022
Journal: Fluids Barriers CNS
Title: ROS attenuates TET2-dependent ZO-1 epigenetic expression in cerebral vascular endothelial cells.
Volume: 19
Issue: 1
Pages: 73
Publication
First Author: Tsagaratou A
Year: 2017
Journal: Nat Immunol
Title: TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells.
Volume: 18
Issue: 1
Pages: 45-53
Publication
First Author: Cai Z
Year: 2020
Journal: Cell Rep
Title: Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells.
Volume: 31
Issue: 12
Pages: 107816
Publication
First Author: Izzo F
Year: 2020
Journal: Nat Genet
Title: DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Volume: 52
Issue: 4
Pages: 378-387
Publication
First Author: Kubota S
Year: 2019
Journal: Nat Commun
Title: Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm.
Volume: 10
Issue: 1
Pages: 1653
Publication
First Author: Ravichandran M
Year: 2019
Journal: Cell Rep
Title: Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells.
Volume: 28
Issue: 8
Pages: 1993-2003.e5
Publication
First Author: Wang H
Year: 2013
Journal: Cell
Title: One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.
Volume: 153
Issue: 4
Pages: 910-8
Publication
First Author: Yang J
Year: 2016
Journal: Cell Rep
Title: Tet Enzymes Regulate Telomere Maintenance and Chromosomal Stability of Mouse ESCs.
Volume: 15
Issue: 8
Pages: 1809-21
Publication
First Author: Shrestha R
Year: 2020
Journal: Blood Adv
Title: Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status.
Volume: 4
Issue: 5
Pages: 845-854
Publication  
First Author: Martínez-Valiente C
Year: 2021
Journal: Int J Mol Sci
Title: Aberrant Alternative Splicing in U2af1/Tet2 Double Mutant Mice Contributes to Major Hematological Phenotypes.
Volume: 22
Issue: 13
Publication
First Author: Khoueiry R
Year: 2017
Journal: Nat Genet
Title: Lineage-specific functions of TET1 in the postimplantation mouse embryo.
Volume: 49
Issue: 7
Pages: 1061-1072
Publication
First Author: Inoue S
Year: 2016
Journal: Cancer Cell
Title: Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.
Volume: 30
Issue: 2
Pages: 337-348
Publication
First Author: Fang S
Year: 2019
Journal: Nat Commun
Title: Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development.
Volume: 10
Issue: 1
Pages: 4297
Publication
First Author: Wang Q
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A mosaic analysis system with Cre or Tomato expression in the mouse.
Volume: 117
Issue: 45
Pages: 28212-28220
Publication
First Author: Meisel M
Year: 2018
Journal: Nature
Title: Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
Volume: 557
Issue: 7706
Pages: 580-584
Publication
First Author: Peng V
Year: 2022
Journal: Nat Immunol
Title: Whole-genome profiling of DNA methylation and hydroxymethylation identifies distinct regulatory programs among innate lymphocytes.
Volume: 23
Issue: 4
Pages: 619-631
Publication
First Author: Tara S
Year: 2018
Journal: Blood
Title: Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome.
Volume: 132
Issue: 23
Pages: 2470-2483
Publication
First Author: Kim H
Year: 2021
Journal: Genome Biol
Title: Ten-eleven translocation protein 1 modulates medulloblastoma progression.
Volume: 22
Issue: 1
Pages: 125
Publication
First Author: Meng C
Year: 2021
Journal: Hum Mol Genet
Title: Ten-eleven translocation 2 modulates allergic inflammation by 5-hydroxymethylcytosine remodeling of immunologic pathways.
Volume: 30
Issue: 21
Pages: 1985-1995
Publication
First Author: Mouly E
Year: 2018
Journal: Blood Adv
Title: B-cell tumor development in Tet2-deficient mice.
Volume: 2
Issue: 6
Pages: 703-714
Publication  
First Author: Qin W
Year: 2021
Journal: Cells
Title: Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by Escherichia coli.
Volume: 11
Issue: 1
Publication  
First Author: Qin W
Year: 2022
Journal: Cytokine
Title: Myeloid cell tet methylcytosine dioxygenase 2 does not affect the host response during gram-negative bacterial pneumonia and sepsis.
Volume: 154
Pages: 155876
Publication
First Author: Tao H
Year: 2021
Journal: Hum Mol Genet
Title: Loss of ten-eleven translocation 2 induces cardiac hypertrophy and fibrosis through modulating ERK signaling pathway.
Volume: 30
Issue: 10
Pages: 865-879
Publication
First Author: Aivalioti MM
Year: 2022
Journal: Blood Cancer Discov
Title: PU.1-Dependent Enhancer Inhibition Separates Tet2-Deficient Hematopoiesis from Malignant Transformation.
Volume: 3
Issue: 5
Pages: 444-467
Publication
First Author: Miller PG
Year: 2022
Journal: Blood
Title: Association of clonal hematopoiesis with chronic obstructive pulmonary disease.
Volume: 139
Issue: 3
Pages: 357-368
UniProt Feature
Begin: 1
Description: Methylcytosine dioxygenase TET2
Type: chain
End: 1912
Publication
First Author: Yang R
Year: 2015
Journal: Immunity
Title: Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis.
Volume: 43
Issue: 2
Pages: 251-63
Publication
First Author: Nakatsukasa H
Year: 2019
Journal: Int Immunol
Title: Loss of TET proteins in regulatory T cells promotes abnormal proliferation, Foxp3 destabilization and IL-17 expression.
Volume: 31
Issue: 5
Pages: 335-347
Publication
First Author: Bonvin E
Year: 2019
Journal: Cancer Res
Title: TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression.
Volume: 79
Issue: 3
Pages: 482-494
Publication
First Author: Zhang Q
Year: 2021
Journal: Hum Mol Genet
Title: Stress modulates Ahi1-dependent nuclear localization of ten-eleven translocation protein 2.
Volume: 30
Issue: 22
Pages: 2149-2160
Publication
First Author: Chen H
Year: 2014
Journal: Nucleic Acids Res
Title: Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter.
Volume: 42
Issue: 3
Pages: 1563-74
Publication
First Author: Kunimoto H
Year: 2017
Journal: Blood
Title: Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells.
Volume: 129
Issue: 13
Pages: 1779-1790
Publication
First Author: Shih AH
Year: 2017
Journal: Cancer Discov
Title: Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.
Volume: 7
Issue: 5
Pages: 494-505
Publication  
First Author: Ramdas B
Year: 2022
Journal: JCI Insight
Title: Combined heterozygosity of FLT3 ITD, TET2, and DNMT3A results in aggressive leukemia.
Volume: 7
Issue: 17
Publication
First Author: Joshi SR
Year: 2020
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation.
Volume: 318
Issue: 4
Pages: L773-L786
Publication
First Author: Dzitoyeva S
Year: 2012
Journal: Neurobiol Aging
Title: Effect of aging on 5-hydroxymethylcytosine in brain mitochondria.
Volume: 33
Issue: 12
Pages: 2881-91
Publication
First Author: Doege CA
Year: 2012
Journal: Nature
Title: Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2.
Volume: 488
Issue: 7413
Pages: 652-5
Publication
First Author: Kurian JR
Year: 2016
Journal: Endocrinology
Title: The Methylcytosine Dioxygenase Ten-Eleven Translocase-2 (tet2) Enables Elevated GnRH Gene Expression and Maintenance of Male Reproductive Function.
Volume: 157
Issue: 9
Pages: 3588-603
Publication
First Author: López-Moyado IF
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Paradoxical association of TET loss of function with genome-wide DNA hypomethylation.
Volume: 116
Issue: 34
Pages: 16933-16942
Publication
First Author: Li SY
Year: 2019
Journal: J Am Soc Nephrol
Title: DNMT1 in Six2 Progenitor Cells Is Essential for Transposable Element Silencing and Kidney Development.
Volume: 30
Issue: 4
Pages: 594-609
Publication  
First Author: Lio CJ
Year: 2019
Journal: Sci Immunol
Title: TET enzymes augment activation-induced deaminase (AID) expression via 5-hydroxymethylcytosine modifications at the Aicda superenhancer.
Volume: 4
Issue: 34
Publication
First Author: Wu MJ
Year: 2022
Journal: Cancer Discov
Title: Mutant IDH Inhibits IFNγ-TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma.
Volume: 12
Issue: 3
Pages: 812-835
Publication
First Author: Lobry C
Year: 2013
Journal: J Exp Med
Title: Notch pathway activation targets AML-initiating cell homeostasis and differentiation.
Volume: 210
Issue: 2
Pages: 301-19
Publication
First Author: Jaiswal S
Year: 2017
Journal: N Engl J Med
Title: Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.
Volume: 377
Issue: 2
Pages: 111-121
Publication
First Author: Agrawal M
Year: 2022
Journal: Blood
Title: TET2-mutant clonal hematopoiesis and risk of gout.
Volume: 140
Issue: 10
Pages: 1094-1103
Publication  
First Author: Hayashi T
Year: 2022
Journal: Differentiation
Title: Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis.
Volume: 125
Pages: 45-53
Publication
First Author: Lio CJ
Year: 2019
Journal: Blood
Title: Dysregulation of the TET family of epigenetic regulators in lymphoid and myeloid malignancies.
Volume: 134
Issue: 18
Pages: 1487-1497
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Zebley CC
Year: 2021
Journal: Cell Rep
Title: Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation.
Volume: 37
Issue: 2
Pages: 109796
Publication
First Author: Hu X
Year: 2014
Journal: Cell Stem Cell
Title: Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming.
Volume: 14
Issue: 4
Pages: 512-22
Publication
First Author: Li Y
Year: 2011
Journal: Genet Mol Res
Title: Gene expression profiling: identification of genes with altered expression in Ayu17-449 knockout mice.
Volume: 10
Issue: 3
Pages: 1533-44
Publication
First Author: Kunimoto H
Year: 2014
Journal: Blood
Title: Tet2-mutated myeloid progenitors possess aberrant in vitro self-renewal capacity.
Volume: 123
Issue: 18
Pages: 2897-9
Publication
First Author: Tang H
Year: 2008
Journal: Transgenic Res
Title: Characterization of Ayu17-449 gene expression and resultant kidney pathology in a knockout mouse model.
Volume: 17
Issue: 4
Pages: 599-608
GXD Expression      
Probe: MGI:4836754
Assay Type: RT-PCR
Annotation Date: 2010-10-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:4836831
Age: postnatal
Image: S5
Specimen Label: Brain cortex
Specimen Num: 4
GXD Expression      
Probe: MGI:4836754
Assay Type: RT-PCR
Annotation Date: 2010-10-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:4836831
Age: postnatal
Image: S5
Specimen Label: Brain Stem
Specimen Num: 5
GXD Expression      
Probe: MGI:4836754
Assay Type: RT-PCR
Annotation Date: 2010-10-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:4836831
Age: postnatal
Image: S5
Specimen Label: Cerebellum
Specimen Num: 6
GXD Expression      
Probe: MGI:4836754
Assay Type: RT-PCR
Annotation Date: 2010-10-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4836831
Age: postnatal
Image: S5
Specimen Label: Thymus
Specimen Num: 7
GXD Expression      
Probe: MGI:4836754
Assay Type: RT-PCR
Annotation Date: 2010-10-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4836831
Age: postnatal
Image: S5
Specimen Label: Heart
Specimen Num: 8
GXD Expression      
Probe: MGI:4836754
Assay Type: RT-PCR
Annotation Date: 2010-10-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:4836831
Age: postnatal
Image: S5
Specimen Label: Lung
Specimen Num: 9
GXD Expression      
Probe: MGI:4836754
Assay Type: RT-PCR
Annotation Date: 2010-10-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:4836831
Age: postnatal
Image: S5
Specimen Label: Olfactory Bulb
Specimen Num: 10
GXD Expression      
Probe: MGI:4836754
Assay Type: RT-PCR
Annotation Date: 2010-10-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:4836831
Age: postnatal
Image: S5
Specimen Label: Spleen
Specimen Num: 11