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Search results 401 to 500 out of 610 for Tet2

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:6159747
Assay Type: RNA in situ
Annotation Date: 2018-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6159943
Age: embryonic day 16.5
Specimen Label: S4P
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
   
Probe: MGI:5829720
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Moderate
Sex: Male
Emaps: EMAPS:3612625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5829743
Age: embryonic day 17.5
Specimen Label: Supplementary Table E17.5 male
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:5829720
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Moderate
Sex: Male
Emaps: EMAPS:3612628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5829743
Age: postnatal day 5
Specimen Label: Supplementary Table P5 male
Detected: true
Specimen Num: 11
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Publication
36522157 | J:337772
First Author: Liang X
Year: 2023
Journal: J Am Soc Nephrol
Title: Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.
Volume: 34
Issue: 4
Pages: 572-589
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Publication
36202795 | J:330330
First Author: Thaler R
Year: 2022
Journal: Nat Commun
Title: Vitamin C epigenetically controls osteogenesis and bone mineralization.
Volume: 13
Issue: 1
Pages: 5883
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Publication
26607761 | J:228006
 
First Author: An J
Year: 2015
Journal: Nat Commun
Title: Acute loss of TET function results in aggressive myeloid cancer in mice.
Volume: 6
Pages: 10071
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Publication
28783731 | J:253140
First Author: Xu T
Year: 2017
Journal: Nature
Title: Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism.
Volume: 548
Issue: 7666
Pages: 228-233
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Publication
32083332 | J:300691
First Author: Joshi HR
Year: 2020
Journal: J Leukoc Biol
Title: Frontline Science: Cxxc5 expression alters cell cycle and myeloid differentiation of mouse hematopoietic stem and progenitor cells.
Volume: 108
Issue: 2
Pages: 469-484
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Publication
24218140 | J:208092
First Author: Abdel-Wahab O
Year: 2013
Journal: J Exp Med
Title: Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo.
Volume: 210
Issue: 12
Pages: 2641-59
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Publication
29991556 | J:266048
First Author: Shepherd MS
Year: 2018
Journal: Blood
Title: Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal.
Volume: 132
Issue: 8
Pages: 791-803
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Publication
33452460 | J:302556
First Author: Bai J
Year: 2021
Journal: Oncogene
Title: Overexpression of Hmga2 activates Igf2bp2 and remodels transcriptional program of Tet2-deficient stem cells in myeloid transformation.
Volume: 40
Issue: 8
Pages: 1531-1541
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Publication
24214992 | J:211897
First Author: Zhao B
Year: 2014
Journal: Nucleic Acids Res
Title: Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism.
Volume: 42
Issue: 3
Pages: 1593-605
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Publication
21816367 | J:175858
First Author: Dawlaty MM
Year: 2011
Journal: Cell Stem Cell
Title: Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.
Volume: 9
Issue: 2
Pages: 166-75
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Publication
25915124 | J:322365
First Author: Etchegaray JP
Year: 2015
Journal: Nat Cell Biol
Title: The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.
Volume: 17
Issue: 5
Pages: 545-57
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Publication
27091986 | J:232209
First Author: Orlanski S
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Tissue-specific DNA demethylation is required for proper B-cell differentiation and function.
Volume: 113
Issue: 18
Pages: 5018-23
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Publication
24735881 | J:329181
First Author: Dawlaty MM
Year: 2014
Journal: Dev Cell
Title: Loss of Tet enzymes compromises proper differentiation of embryonic stem cells.
Volume: 29
Issue: 1
Pages: 102-11
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Publication
34919053 | J:317728
   
First Author: Stoyanova E
Year: 2021
Journal: Elife
Title: 5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function.
Volume: 10
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Publication
29795194 | J:262977
First Author: Reizel Y
Year: 2018
Journal: Nat Commun
Title: Postnatal DNA demethylation and its role in tissue maturation.
Volume: 9
Issue: 1
Pages: 2040
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Publication
35235365 | J:329158
First Author: Ma L
Year: 2022
Journal: Sci Adv
Title: Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis.
Volume: 8
Issue: 9
Pages: eabm3470
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Publication
35499082 | J:338734
 
First Author: Gao X
Year: 2022
Journal: J Clin Invest
Title: Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus.
Volume: 132
Issue: 9
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Publication
29048538 | J:248489
First Author: Someya K
Year: 2017
Journal: Int Immunol
Title: Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation.
Volume: 29
Issue: 8
Pages: 365-375
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Publication
36681742 | J:333989
First Author: Romine KA
Year: 2023
Journal: Leukemia
Title: BET inhibitors rescue anti-PD1 resistance by enhancing TCF7 accessibility in leukemia-derived terminally exhausted CD8(+) T cells.
Volume: 37
Issue: 3
Pages: 580-592
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Publication
26773568 | J:310739
First Author: Oshima M
Year: 2016
Journal: Exp Hematol
Title: Ezh2 regulates the Lin28/let-7 pathway to restrict activation of fetal gene signature in adult hematopoietic stem cells.
Volume: 44
Issue: 4
Pages: 282-96.e3
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Publication
31844322 | J:342578
First Author: Xiang Y
Year: 2020
Journal: Nat Genet
Title: Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency.
Volume: 52
Issue: 1
Pages: 95-105
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Publication
31578525 | J:283351
First Author: Yoshimi A
Year: 2019
Journal: Nature
Title: Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis.
Volume: 574
Issue: 7777
Pages: 273-277
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Publication
26903244 | J:232927
First Author: Yue X
Year: 2016
Journal: J Exp Med
Title: Control of Foxp3 stability through modulation of TET activity.
Volume: 213
Issue: 3
Pages: 377-97
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Publication
24838012 | J:334511
First Author: Pfaffeneder T
Year: 2014
Journal: Nat Chem Biol
Title: Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.
Volume: 10
Issue: 7
Pages: 574-81
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Publication
22569552 | J:184512
First Author: Tan L
Year: 2012
Journal: Development
Title: Tet family proteins and 5-hydroxymethylcytosine in development and disease.
Volume: 139
Issue: 11
Pages: 1895-902
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Publication
23992847 | J:204541
First Author: Yang H
Year: 2013
Journal: Cell
Title: One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering.
Volume: 154
Issue: 6
Pages: 1370-9
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Publication
21321204 | J:169869
First Author: Iqbal K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine.
Volume: 108
Issue: 9
Pages: 3642-7
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Publication
30554962 | J:286905
First Author: Zviran A
Year: 2019
Journal: Cell Stem Cell
Title: Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules.
Volume: 24
Issue: 2
Pages: 328-341.e9
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Publication
35908548 | J:330810
First Author: Cheng S
Year: 2022
Journal: Cell
Title: The intrinsic and extrinsic effects of TET proteins during gastrulation.
Volume: 185
Issue: 17
Pages: 3169-3185.e20
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Publication
35443168 | J:325006
First Author: Cortes JR
Year: 2022
Journal: Cell Rep
Title: Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma.
Volume: 39
Issue: 3
Pages: 110695
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Publication
38495876 | J:346379
 
First Author: Flynn PA
Year: 2024
Journal: Front Immunol
Title: Leukemic mutation FLT3-ITD is retained in dendritic cells and disrupts their homeostasis leading to expanded Th17 frequency.
Volume: 15
Pages: 1297338
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Publication
33636128 | J:303949
First Author: Heyde A
Year: 2021
Journal: Cell
Title: Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis.
Volume: 184
Issue: 5
Pages: 1348-1361.e22
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Publication
34698806 | J:325744
 
First Author: Kim PG
Year: 2021
Journal: J Exp Med
Title: Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis.
Volume: 218
Issue: 12
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Publication
33134768 | J:330735
First Author: Smeriglio P
Year: 2020
Journal: JBMR Plus
Title: TET1 Directs Chondrogenic Differentiation by Regulating SOX9 Dependent Activation of Col2a1 and Acan In Vitro.
Volume: 4
Issue: 8
Pages: e10383
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Publication
33846634 | J:320794
First Author: Inoue D
Year: 2021
Journal: Nat Genet
Title: Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition.
Volume: 53
Issue: 5
Pages: 707-718
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Publication
28825709 | J:269878
First Author: Agathocleous M
Year: 2017
Journal: Nature
Title: Ascorbate regulates haematopoietic stem cell function and leukaemogenesis.
Volume: 549
Issue: 7673
Pages: 476-481
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Publication
32341038 | J:290321
First Author: Yokomizo-Nakano T
Year: 2020
Journal: Cancer Res
Title: Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome.
Volume: 80
Issue: 12
Pages: 2523-2536
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Publication
34099715 | J:330875
First Author: Moyon S
Year: 2021
Journal: Nat Commun
Title: TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice.
Volume: 12
Issue: 1
Pages: 3359
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Publication
35045331 | J:329125
First Author: Muto T
Year: 2022
Journal: Cell Stem Cell
Title: TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity.
Volume: 29
Issue: 2
Pages: 298-314.e9
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Publication
33268865 | J:299972
First Author: Lu Y
Year: 2020
Journal: Nature
Title: Reprogramming to recover youthful epigenetic information and restore vision.
Volume: 588
Issue: 7836
Pages: 124-129
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Publication
36550214 | J:336536
First Author: Anderson NR
Year: 2023
Journal: Leukemia
Title: Microenvironmental CXCL12 deletion enhances Flt3-ITD acute myeloid leukemia stem cell response to therapy by reducing p38 MAPK signaling.
Volume: 37
Issue: 3
Pages: 560-570
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Publication
28538185 | J:330778
First Author: Hassan HM
Year: 2017
Journal: Cell Rep
Title: Regulation of Active DNA Demethylation through RAR-Mediated Recruitment of a TET/TDG Complex.
Volume: 19
Issue: 8
Pages: 1685-1697
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Publication
25557551 | J:219980
First Author: Nakagawa T
Year: 2015
Journal: Mol Cell
Title: CRL4(VprBP) E3 ligase promotes monoubiquitylation and chromatin binding of TET dioxygenases.
Volume: 57
Issue: 2
Pages: 247-260
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Publication
29108636 | J:258221
 
First Author: Rakoczy J
Year: 2017
Journal: Placenta
Title: Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation.
Volume: 59
Pages: 46-56
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Publication
30778220 | J:282946
First Author: Liu L
Year: 2019
Journal: Nat Cell Biol
Title: Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells.
Volume: 21
Issue: 3
Pages: 328-337
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Publication
34661337 | J:318688
First Author: Nishikawa K
Year: 2021
Journal: EMBO Rep
Title: Osteoclasts adapt to physioxia perturbation through DNA demethylation.
Volume: 22
Issue: 12
Pages: e53035
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Publication
36880575 | J:335733
First Author: Teghanemt A
Year: 2023
Journal: EMBO Rep
Title: DNA demethylation fine-tunes IL-2 production during thymic regulatory T cell differentiation.
Volume: 24
Issue: 5
Pages: e55543
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Publication
35304452 | J:333574
First Author: Teghanemt A
Year: 2022
Journal: Nat Commun
Title: CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element.
Volume: 13
Issue: 1
Pages: 1477
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Publication
29530881 | J:264121
 
First Author: SanMiguel JM
Year: 2018
Journal: Development
Title: Imprinted gene dysregulation in a Tet1 null mouse model is stochastic and variable in the germline and offspring.
Volume: 145
Issue: 7
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Publication
28614801 | J:279154
 
First Author: Shen J
Year: 2017
Journal: JCI Insight
Title: DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism.
Volume: 2
Issue: 12
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Publication
26902115 | J:234375
First Author: Kim H
Year: 2016
Journal: Biochem Biophys Res Commun
Title: TET1 contributes to neurogenesis onset time during fetal brain development in mice.
Volume: 471
Issue: 4
Pages: 437-43
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Publication
14621295 | J:86686
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 4
Pages: 167-80
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Publication
21490601 | J:172063
First Author: Williams K
Year: 2011
Journal: Nature
Title: TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
Volume: 473
Issue: 7347
Pages: 343-8
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Publication
27941786 | J:260180
First Author: Herzig Y
Year: 2017
Journal: Nat Immunol
Title: Transcriptional programs that control expression of the autoimmune regulator gene Aire.
Volume: 18
Issue: 2
Pages: 161-172
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Publication
36539616 | J:333558
First Author: Wu F
Year: 2023
Journal: Nat Genet
Title: Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine.
Volume: 55
Issue: 1
Pages: 100-111
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Publication
26576615 | J:271018
First Author: Auclair G
Year: 2016
Journal: Genome Res
Title: EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos.
Volume: 26
Issue: 2
Pages: 192-202
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Publication
23151479 | J:194101
First Author: Yamaguchi S
Year: 2012
Journal: Nature
Title: Tet1 controls meiosis by regulating meiotic gene expression.
Volume: 492
Issue: 7429
Pages: 443-7
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Publication
26989192 | J:242825
First Author: Fong KS
Year: 2016
Journal: Dis Model Mech
Title: A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.
Volume: 9
Issue: 5
Pages: 585-96
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Publication
31361780 | J:279721
First Author: Linscott ML
Year: 2019
Journal: PLoS One
Title: TET1 regulates fibroblast growth factor 8 transcription in gonadotropin releasing hormone neurons.
Volume: 14
Issue: 7
Pages: e0220530
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Publication
36630508 | J:332685
First Author: Chen GD
Year: 2023
Journal: Sci Adv
Title: DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation.
Volume: 9
Issue: 2
Pages: eabo7605
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Publication
27930333 | J:239071
First Author: Li X
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling.
Volume: 113
Issue: 51
Pages: E8267-E8276
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Publication
20887958 | J:165653
First Author: Wilson NK
Year: 2010
Journal: Cell Stem Cell
Title: Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.
Volume: 7
Issue: 4
Pages: 532-44
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Publication
27895551 | J:312335
 
First Author: Reyes-Aguirre LI
Year: 2016
Journal: Front Neurosci
Title: Oct4 Methylation-Mediated Silencing As an Epigenetic Barrier Preventing Müller Glia Dedifferentiation in a Murine Model of Retinal Injury.
Volume: 10
Pages: 523
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Publication
27760115 | J:239417
First Author: Dai HQ
Year: 2016
Journal: Nature
Title: TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling.
Volume: 538
Issue: 7626
Pages: 528-532
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Publication
23920106 | J:202864
First Author: Keil KP
Year: 2013
Journal: Gene Expr Patterns
Title: Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract.
Volume: 13
Issue: 8
Pages: 413-24
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Publication
24357321 | J:205485
First Author: Yu C
Year: 2013
Journal: Science
Title: CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.
Volume: 342
Issue: 6165
Pages: 1518-21
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Publication
32892421 | J:306136
First Author: Manti M
Year: 2020
Journal: FASEB J
Title: Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice.
Volume: 34
Issue: 11
Pages: 14440-14457
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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