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Search results 301 to 372 out of 372 for Pi4ka

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4425167
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824702
Age: embryonic day 14.5
Image: euxassay_013806_18
Specimen Label: euxassay_013806_18
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:4425167
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824702
Age: embryonic day 14.5
Image: euxassay_013806_19
Specimen Label: euxassay_013806_19
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:4425167
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824702
Age: embryonic day 14.5
Image: euxassay_013806_20
Specimen Label: euxassay_013806_20
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:4425167
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824702
Age: embryonic day 14.5
Image: euxassay_013806_21
Specimen Label: euxassay_013806_21
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:4425167
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824702
Age: embryonic day 14.5
Image: euxassay_013806_08
Specimen Label: euxassay_013806_08
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4425167
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824702
Age: embryonic day 14.5
Image: euxassay_013806_09
Specimen Label: euxassay_013806_09
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4425167
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824702
Age: embryonic day 14.5
Image: euxassay_013806_10
Specimen Label: euxassay_013806_10
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:4425167
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824702
Age: embryonic day 14.5
Image: euxassay_013806_13
Specimen Label: euxassay_013806_13
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:4425167
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824702
Age: embryonic day 14.5
Image: euxassay_013806_14
Specimen Label: euxassay_013806_14
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:4425167
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824702
Age: embryonic day 14.5
Image: euxassay_013806_15
Specimen Label: euxassay_013806_15
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:4425167
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824702
Age: embryonic day 14.5
Image: euxassay_013806_16
Specimen Label: euxassay_013806_16
Detected: true
Specimen Num: 13
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Allele
Hycc1<+> | MGI:2439881
   
Name: hyccin PI4KA lipid kinase complex subunit 1; wild type
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Allele
Hycc2<+> | MGI:3810109
 
Name: hyccin PI4KA lipid kinase complex subunit 2; wild type
Allele Type: Not Specified
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Allele
Hycc1<em8Gpt> | MGI:7298829
Name: hyccin PI4KA lipid kinase complex subunit 1; endonuclease-mediated mutation 8, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hycc1<em1(IMPC)Ccpcz> | MGI:6341927
Name: hyccin PI4KA lipid kinase complex subunit 1; endonuclease-mediated mutation 1, Institute of Molecular Genetics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hycc2<em7Gpt> | MGI:7576373
Name: hyccin PI4KA lipid kinase complex subunit 2; endonuclease-mediated mutation 7, GemPharmatech
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hycc2<Gt(OST440358)Lex> | MGI:4318040
 
Name: hyccin PI4KA lipid kinase complex subunit 2; gene trap OST440358, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Hycc2<tm1(KOMP)Vlcg> | MGI:5051475
Name: hyccin PI4KA lipid kinase complex subunit 2; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Hycc2<tm1a(EUCOMM)Hmgu> | MGI:4435671
Name: hyccin PI4KA lipid kinase complex subunit 2; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Hycc2<Gt(OST456938)Lex> | MGI:4324152
 
Name: hyccin PI4KA lipid kinase complex subunit 2; gene trap OST456938, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Hycc2<Gt(OST315534)Lex> | MGI:4277181
 
Name: hyccin PI4KA lipid kinase complex subunit 2; gene trap OST315534, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Hycc2<tm1e(EUCOMM)Hmgu> | MGI:4436540
Name: hyccin PI4KA lipid kinase complex subunit 2; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Hycc1<em1Gpt> | MGI:7298828
Name: hyccin PI4KA lipid kinase complex subunit 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Hycc1<tm1Vlcg> | MGI:5693960
Name: hyccin PI4KA lipid kinase complex subunit 1; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Hycc1<Gt(OST222945)Lex> | MGI:4239835
 
Name: hyccin PI4KA lipid kinase complex subunit 1; gene trap OST222945, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Del(16Pi4ka-Hira)1Atai | MGI:6729278
Name: deletion, Chr 16, Atsu Aiba 1
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6767751 | C57BL/6JGpt-Hycc1<em8Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6407733 | C57BL/6N-Hycc1<em1(IMPC)Ccpcz>/Ccpcz
Attribute String: coisogenic, targeted mutation
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Strain
MGI:6335803 | C57BL/6NCrl-Hycc1<em1(IMPC)Ccpcz>/Ph
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7577359 | C57BL/6JGpt-Hycc2<em7Gpt>/Gpt
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Hycc2<Gt(IST12358C1)Tigm> | MGI:4069963
 
Name: hyccin PI4KA lipid kinase complex subunit 2; gene trap IST12358C1, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Hycc2<Gt(IST11389A3)Tigm> | MGI:5149170
 
Name: hyccin PI4KA lipid kinase complex subunit 2; gene trap IST11389A3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Strain
MGI:6767752 | C57BL/6JGpt-Hycc1<em1Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Hycc1/Hycc1
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hycc1/Hycc1
Background: C57BL/6N-Hycc1/Ccpcz
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:6770483 | C57BL/6N-Del(16Pi4ka-Hira)1Atai/Atai
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6729287 | C57BL/6N-Del(16Pi4ka-Hira)1Atai
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
32066675 | J:285407
First Author: Saito R
Year: 2020
Journal: Transl Psychiatry
Title: Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus.
Volume: 10
Issue: 1
Pages: 35
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Publication
37238632 | J:336143
 
First Author: Tabata H
Year: 2023
Journal: Biomolecules
Title: Histological Analysis of a Mouse Model of the 22q11.2 Microdeletion Syndrome.
Volume: 13
Issue: 5
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Publication
33341442 | J:314592
 
First Author: Arioka Y
Year: 2021
Journal: EBioMedicine
Title: Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons.
Volume: 63
Pages: 103138
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Genotype
Genotype
Symbol: Del(16Pi4ka-Hira)1Atai/+
Background: C57BL/6N-Del(16Pi4ka-Hira)1Atai
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0112347 | hereditary spastic paraplegia 84
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Allele
Pi4ka<m1Btlr> | MGI:6200379
Name: phosphatidylinositol 4-kinase alpha; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6200380 | C57BL/6J-Pi4ka<m1Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Genotype
Genotype
Symbol: Pi4ka/Pi4ka
Background: C57BL/6J-Pi4ka
Zygosity: hm
Has Mutant Allele: true
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Publication
19515974 | J:150044
First Author: Fancy SP
Year: 2009
Journal: Genes Dev
Title: Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS.
Volume: 23
Issue: 13
Pages: 1571-85
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Protein
Q3UFQ5
Organism: Mus musculus/domesticus
Length: 287  
Fragment?: false
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Protein Domain
IPR045819 | TTC7_N
Type: Domain
Description: This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyses the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane [, ].
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Publication
30930167 | J:284160
First Author: Ren C
Year: 2019
Journal: Dev Cell
Title: Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment.
Volume: 49
Issue: 2
Pages: 206-219.e7
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Protein
D6RG81
Organism: Mus musculus/domesticus
Length: 210  
Fragment?: false
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Protein
F6ZVR4
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: true
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Publication
29229838 | -
First Author: Lees JA
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Architecture of the human PI4KIIIα lipid kinase complex.
Volume: 114
Issue: 52
Pages: 13720-13725
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Protein
Q8BGB2
Organism: Mus musculus/domesticus
Length: 858  
Fragment?: false
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Protein
E9Q6P5
Organism: Mus musculus/domesticus
Length: 843  
Fragment?: false
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Protein
A0A1Y7VL44
Organism: Mus musculus/domesticus
Length: 860  
Fragment?: false
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Protein
Q8C9T8
Organism: Mus musculus/domesticus
Length: 746  
Fragment?: false
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Protein
D3Z0R8
Organism: Mus musculus/domesticus
Length: 822  
Fragment?: false
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Protein
Q3TNI8
Organism: Mus musculus/domesticus
Length: 524  
Fragment?: true
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Publication
16919269 | J:112701
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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