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Search results 101 to 193 out of 193 for Trrap

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0.028s
Type Details Score
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_21
Specimen Label: euxassay_013672_21
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_22
Specimen Label: euxassay_013672_22
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_05
Specimen Label: euxassay_013672_05
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_06
Specimen Label: euxassay_013672_06
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_21
Specimen Label: euxassay_013672_21
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_22
Specimen Label: euxassay_013672_22
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_07
Specimen Label: euxassay_013672_07
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_08
Specimen Label: euxassay_013672_08
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_09
Specimen Label: euxassay_013672_09
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_19
Specimen Label: euxassay_013672_19
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_20
Specimen Label: euxassay_013672_20
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_12
Specimen Label: euxassay_013672_12
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_13
Specimen Label: euxassay_013672_13
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_16
Specimen Label: euxassay_013672_16
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_17
Specimen Label: euxassay_013672_17
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4417010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828945
Age: embryonic day 14.5
Image: euxassay_013672_18
Specimen Label: euxassay_013672_18
Detected: true
Specimen Num: 13
Publication
First Author: Ogryzko VV
Year: 1998
Journal: Cell
Title: Histone-like TAFs within the PCAF histone acetylase complex.
Volume: 94
Issue: 1
Pages: 35-44
Publication
First Author: Helmlinger D
Year: 2006
Journal: PLoS Biol
Title: Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction.
Volume: 4
Issue: 3
Pages: e67
Publication
First Author: Stante M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks.
Volume: 106
Issue: 13
Pages: 5093-8
Publication
First Author: Kim J
Year: 2010
Journal: Cell
Title: A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.
Volume: 143
Issue: 2
Pages: 313-24
Publication
First Author: Nagy Z
Year: 2007
Journal: Oncogene
Title: Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.
Volume: 26
Issue: 37
Pages: 5341-57
Publication
First Author: Schiltz RL
Year: 1999
Journal: J Biol Chem
Title: Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates.
Volume: 274
Issue: 3
Pages: 1189-92
Publication
First Author: Nagy Z
Year: 2009
Journal: Mol Cell Biol
Title: The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.
Volume: 29
Issue: 6
Pages: 1649-60
Publication
First Author: Kioussi C
Year: 2002
Journal: Cell
Title: Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development.
Volume: 111
Issue: 5
Pages: 673-85
Publication
First Author: Brand M
Year: 2001
Journal: EMBO J
Title: UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation.
Volume: 20
Issue: 12
Pages: 3187-96
Publication
First Author: Zhao Y
Year: 2008
Journal: Mol Cell
Title: A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.
Volume: 29
Issue: 1
Pages: 92-101
Publication
First Author: Jacquet K
Year: 2016
Journal: Mol Cell
Title: The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.
Volume: 62
Issue: 3
Pages: 409-421
Publication
First Author: Krebs AR
Year: 2010
Journal: EMBO Rep
Title: ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.
Volume: 11
Issue: 7
Pages: 541-7
Publication
First Author: Bardot P
Year: 2017
Journal: Development
Title: The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo.
Volume: 144
Issue: 20
Pages: 3808-3818
Publication  
First Author: Tamplin OJ
Year: 2008
Journal: BMC Genomics
Title: Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Volume: 9
Pages: 511
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication
First Author: Robert F
Year: 2006
Journal: Mol Cell Biol
Title: The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair.
Volume: 26
Issue: 2
Pages: 402-12
Publication
First Author: Xia W
Year: 2019
Journal: Clin Genet
Title: Novel TRRAP mutation causes autosomal dominant non-syndromic hearing loss.
Volume: 96
Issue: 4
Pages: 300-308
DO Term
Interaction Experiment
Description: The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc.
Interaction Experiment
Description: The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins.
Publication
First Author: McMahon SB
Year: 2000
Journal: Mol Cell Biol
Title: The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc.
Volume: 20
Issue: 2
Pages: 556-62
Publication
First Author: McMahon SB
Year: 1998
Journal: Cell
Title: The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins.
Volume: 94
Issue: 3
Pages: 363-74
Protein Domain
Type: Repeat
Description: This entry includes transcription-associated protein 1 (Tra1) from yeast and TRRAP from mammals. Budding yeast Tra1 is a subunit of SAGA and NuA4 histone acetyltransferase complexes [, ]. Human TRRAP is an adapter protein found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT) [].This entry represents part of the Tra1 protein composed of α-solenoid repeats that form a ring region [].
Protein Domain
Type: Family
Description: This entry includes transcription-associated protein 1 (Tra1) from yeast and TRRAP from mammals. Budding yeast Tra1 is a subunit of SAGA and NuA4 histone acetyltransferase complexes [, ]. Human TRRAP is an adapter protein found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT) [].
HT Experiment
Series Id: GSE43650
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Sharov G
Year: 2017
Journal: Nat Commun
Title: Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA.
Volume: 8
Issue: 1
Pages: 1556
Protein Domain
Type: Repeat
Description: This entry includes transcription-associated protein 1 (Tra1) from yeast and TRRAP from mammals. Budding yeast Tra1 is a subunit of SAGA and NuA4 histone acetyltransferase complexes [, ]. Human TRRAP is an adapter protein found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT) [].This entry represents part of the Tra1 protein composed of α-solenoid repeats that forms the central region []. This is named as central due to its position relative to the ring region.
Publication
First Author: Brown CE
Year: 2001
Journal: Science
Title: Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit.
Volume: 292
Issue: 5525
Pages: 2333-7
Publication
First Author: Grant PA
Year: 1998
Journal: Mol Cell
Title: The ATM-related cofactor Tra1 is a component of the purified SAGA complex.
Volume: 2
Issue: 6
Pages: 863-7
Protein
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 3859  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 3858  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 3829  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 3587  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 3847  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2565  
Fragment?: false
Protein Domain
Type: Family
Description: TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65kDa subunit 5L (TAF5L) is a component of the a component of the PCAF complex, the human version of the yeast SAGA complex []. TAF5L is also a component of the STAGA transcription coactivator-HAT complex [].The transcription regulatory histone acetylation complex Spt-Ada-Gcn5 acetyltransferase (SAGA) is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes. SAGA preferentially acetylates histones H3 and H2B and deubiquitinates histone H2B []. SAGA is known as PCAF in vertebrates and PCAF acetylates nucleosomal histone H3 []. The SAGA complex consists of at least TRA1, CHD1, SPT7, TAF5, ADA3, SGF73, SPT20/ADA5, SPT8, TAF12, TAF6, HFI1/ADA1, UBP8, GCN5, ADA2, SPT3, SGF29, TAF10, TAF9, SGF11 and SUS1, and some of these components are present as two copies. The complex is built up from distinct modules, each of which has a separate function and crosslinks with either other proteins or other modules in the complex [].The STAGA transcription coactivator-HAT complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors. The STAGA complex is composed of at least SUPT3H, KAT2A, SUPT7L, TAF5L, TAF6L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9 [].
Protein
Organism: Mus musculus/domesticus
Length: 2724  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 374  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 589  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 560  
Fragment?: true
Publication
First Author: Pray-Grant MG
Year: 2005
Journal: Nature
Title: Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation.
Volume: 433
Issue: 7024
Pages: 434-8
Publication
First Author: Han Y
Year: 2014
Journal: EMBO J
Title: Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex.
Volume: 33
Issue: 21
Pages: 2534-46