C-type lectin domain family 12 member B (CLEC12B) is a lectin C-type inhibitory receptor that plays a role in myeloid cell function []. CLEC12A (also known as MICL or DCAL-2) is expressed in monocytes, macrophages, and dendritic-cells (DCs). It serves as a functional receptor on DCs and can internalize and collaborate with TLR or CD40 signaling and regulate immune responses [].
