|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 86 out of 86 for Top1

Category restricted to Publication (x)

0.047s

Categories

Category: Publication
« show all
Type Details Score
Publication
35140396 | J:325942
First Author: Reijns MAM
Year: 2022
Journal: Nature
Title: Signatures of TOP1 transcription-associated mutagenesis in cancer and germline.
Volume: 602
Issue: 7898
Pages: 623-631
•
•
•
•
•
Publication
27231886 | J:236045
First Author: Mabb AM
Year: 2016
Journal: PLoS One
Title: Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.
Volume: 11
Issue: 5
Pages: e0156439
•
•
•
•
•
Publication
11255022 | J:68405
First Author: Smith SF
Year: 2001
Journal: Gene
Title: Characterisation of two topoisomerase 1 genes in the pufferfish (Fugu rubripes).
Volume: 265
Issue: 1-2
Pages: 195-204
•
•
•
•
•
Publication
25404338 | J:216729
First Author: Mabb AM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Topoisomerase 1 inhibition reversibly impairs synaptic function.
Volume: 111
Issue: 48
Pages: 17290-5
•
•
•
•
•
Publication
22080610 | J:303117
First Author: Kobayashi M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation.
Volume: 108
Issue: 48
Pages: 19305-10
•
•
•
•
•
Publication
24798329 | J:216625
First Author: Dalla Rosa I
Year: 2014
Journal: J Biol Chem
Title: Mapping topoisomerase sites in mitochondrial DNA with a poisonous mitochondrial topoisomerase I (Top1mt).
Volume: 289
Issue: 26
Pages: 18595-602
•
•
•
•
•
Publication
- | J:14878
 
First Author: Rettenberger G
Year: 1991
Journal: Cytogenet Cell Genet
Title: Localization of the type I DNA topoisomerase gene in man and mouse
Volume: 58
Pages: 2032 (Abstr.)
•
•
•
•
•
Publication
32327659 | J:292445
First Author: Fragola G
Year: 2020
Journal: Nat Commun
Title: Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration.
Volume: 11
Issue: 1
Pages: 1962
•
•
•
•
•
Publication
18515798 | J:137993
First Author: Lin CP
Year: 2008
Journal: J Biol Chem
Title: A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes.
Volume: 283
Issue: 30
Pages: 21074-83
•
•
•
•
•
Publication
24793032 | J:212924
First Author: Katyal S
Year: 2014
Journal: Nat Neurosci
Title: Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes.
Volume: 17
Issue: 6
Pages: 813-21
•
•
•
•
•
Publication
8111124 | J:16405
First Author: Baumgärtner B
Year: 1994
Journal: Mamm Genome
Title: Mouse genes encoding DNA topoisomerase I.
Volume: 5
Issue: 1
Pages: 19-25
•
•
•
•
•
Publication
8193161 | J:18344
First Author: Baumgärtner B
Year: 1994
Journal: Biochim Biophys Acta
Title: Conserved regulatory elements in the type I DNA topoisomerase gene promoters of mouse and man.
Volume: 1218
Issue: 1
Pages: 123-7
•
•
•
•
•
Publication
8943335 | J:36546
First Author: Morham SG
Year: 1996
Journal: Mol Cell Biol
Title: Targeted disruption of the mouse topoisomerase I gene by camptothecin selection.
Volume: 16
Issue: 12
Pages: 6804-9
•
•
•
•
•
Publication
16261531 | J:104607
First Author: Plaschkes I
Year: 2005
Journal: J Comp Neurol
Title: DNA topoisomerase I in the mouse central nervous system: Age and sex dependence.
Volume: 493
Issue: 3
Pages: 357-69
•
•
•
•
•
Publication
11016921 | J:66711
First Author: Mo YY
Year: 2000
Journal: J Biol Chem
Title: A novel nuclear localization signal in human DNA topoisomerase I.
Volume: 275
Issue: 52
Pages: 41107-13
•
•
•
•
•
Publication
22911747 | J:189886
First Author: Douarre C
Year: 2012
Journal: PLoS One
Title: Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism.
Volume: 7
Issue: 7
Pages: e41094
•
•
•
•
•
Publication
26305952 | J:226811
First Author: Khiati S
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration.
Volume: 112
Issue: 36
Pages: 11282-7
•
•
•
•
•
Publication
9094096 | J:39389
First Author: Cobb J
Year: 1997
Journal: Mol Reprod Dev
Title: Analysis of expression and function of topoisomerase I and II during meiosis in male mice.
Volume: 46
Issue: 4
Pages: 489-98
•
•
•
•
•
Publication
28199696 | J:246108
First Author: Maskey RS
Year: 2017
Journal: Nucleic Acids Res
Title: Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis.
Volume: 45
Issue: 8
Pages: 4564-4576
•
•
•
•
•
Publication
- | J:20791
First Author: Liddell RA
Year: 1994
Journal: Mouse Genome
Title: Chromosomal localization and evolution of topoisomerase I sequences in the Mus genome
Volume: 92
Issue: 3
Pages: 520-22
•
•
•
•
•
Publication
9144489 | J:40206
First Author: Grillot DA
Year: 1997
Journal: J Immunol
Title: Genomic organization, promoter region analysis, and chromosome localization of the mouse bcl-x gene.
Volume: 158
Issue: 10
Pages: 4750-7
•
•
•
•
•
Publication
10334875 | J:55184
First Author: Nanda N
Year: 1999
Journal: Arch Biochem Biophys
Title: Organization and chromosomal mapping of mouse Gh/tissue transglutaminase gene (Tgm2).
Volume: 366
Issue: 1
Pages: 151-6
•
•
•
•
•
Publication
34644582 | J:328271
First Author: Krupa O
Year: 2021
Journal: Cell Rep
Title: NuMorph: Tools for cortical cellular phenotyping in tissue-cleared whole-brain images.
Volume: 37
Issue: 2
Pages: 109802
•
•
•
•
•
Publication
28007908 | J:241438
First Author: Shekhar S
Year: 2017
Journal: Hum Mol Genet
Title: Topoisomerase 1 inhibitor topotecan delays the disease progression in a mouse model of Huntington's disease.
Volume: 26
Issue: 2
Pages: 420-429
•
•
•
•
•
Publication
7842491 | J:22850
First Author: Baloch Z
Year: 1995
Journal: Cell Immunol
Title: Modulation of topoisomerase activities by tumor necrosis factor.
Volume: 160
Issue: 1
Pages: 98-103
•
•
•
•
•
Publication
1372074 | J:2278
First Author: Porteus MH
Year: 1992
Journal: Brain Res Mol Brain Res
Title: Isolation and characterization of a library of cDNA clones that are preferentially expressed in the embryonic telencephalon.
Volume: 12
Issue: 1-3
Pages: 7-22
•
•
•
•
•
Publication
8096488 | J:4311
First Author: Koiwai O
Year: 1993
Journal: Gene
Title: Cloning of the mouse cDNA encoding DNA topoisomerase I and chromosomal location of the gene.
Volume: 125
Issue: 2
Pages: 211-6
•
•
•
•
•
Publication
11756244 | J:73919
First Author: Lebel M
Year: 2002
Journal: Carcinogenesis
Title: Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue.
Volume: 23
Issue: 1
Pages: 213-6
•
•
•
•
•
Publication
9291580 | J:42729
First Author: Leco KJ
Year: 1997
Journal: Dev Genet
Title: Matrix metalloproteinase-9 maps to the distal end of chromosome 2 in the mouse.
Volume: 21
Issue: 1
Pages: 55-60
•
•
•
•
•
Publication
11322760 | J:71014
First Author: Verlaet M
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Genetic imbalances in preleukemic thymuses.
Volume: 283
Issue: 1
Pages: 12-8
•
•
•
•
•
Publication
7806233 | J:19680
First Author: Masaki S
Year: 1994
Journal: Genomics
Title: The gene Bfsp1 for the lens fiber cell beaded-filament structural protein CP94 maps to mouse chromosome 2.
Volume: 22
Issue: 2
Pages: 449-50
•
•
•
•
•
Publication
33836156 | J:308894
First Author: Ho JSY
Year: 2021
Journal: Cell
Title: TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.
Volume: 184
Issue: 10
Pages: 2618-2632.e17
•
•
•
•
•
Publication
22308494 | J:182019
First Author: Gowher H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II.
Volume: 109
Issue: 7
Pages: 2370-5
•
•
•
•
•
Publication
8012118 | J:17621
First Author: Kingsmore SF
Year: 1994
Journal: Mamm Genome
Title: Genetic mapping of DNA topoisomerase I-related sequences to mouse chromosomes 2 and 14.
Volume: 5
Issue: 4
Pages: 247-8
•
•
•
•
•
Publication
33524014 | J:305161
First Author: Dar AA
Year: 2021
Journal: PLoS Biol
Title: The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA.
Volume: 19
Issue: 2
Pages: e3001041
•
•
•
•
•
Publication
7752808 | J:25158
First Author: Giros B
Year: 1995
Journal: Life Sci
Title: Chromosomal localization of opioid peptide and receptor genes in the mouse.
Volume: 56
Issue: 18
Pages: PL369-75
•
•
•
•
•
Publication
16107646 | J:100324
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
•
•
•
•
•
Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
•
•
•
•
•
Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
•
•
•
•
•
Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
•
•
•
•
•
Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
•
•
•
•
•
Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
•
•
•
•
•
Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
•
•
•
•
•
Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
•
•
•
•
•
Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
•
•
•
•
•
Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
•
•
•
•
•
Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
•
•
•
•
•
Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
•
•
•
•
•
Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
•
•
•
•
•
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
23995680 | J:205422
First Author: King IF
Year: 2013
Journal: Nature
Title: Topoisomerases facilitate transcription of long genes linked to autism.
Volume: 501
Issue: 7465
Pages: 58-62
•
•
•
•
•
Publication
20145144 | J:157686
First Author: Zander SA
Year: 2010
Journal: Cancer Res
Title: Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan.
Volume: 70
Issue: 4
Pages: 1700-10
•
•
•
•
•
Publication
32572188 | J:299298
First Author: Jing CB
Year: 2020
Journal: Leukemia
Title: Synthetic lethal targeting of TET2-mutant hematopoietic stem and progenitor cells (HSPCs) with TOP1-targeted drugs and PARP1 inhibitors.
Volume: 34
Issue: 11
Pages: 2992-3006
•
•
•
•
•
Publication
18588899 | J:168879
First Author: Sordet O
Year: 2008
Journal: J Mol Biol
Title: Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I.
Volume: 381
Issue: 3
Pages: 540-9
•
•
•
•
•
Publication
32113985 | J:294118
First Author: Ji L
Year: 2020
Journal: Biochim Biophys Acta Gene Regul Mech
Title: TOPORS, a tumor suppressor protein, contributes to the maintenance of higher-order chromatin architecture.
Volume: 1863
Issue: 5
Pages: 194518
•
•
•
•
•
Publication
22740648 | J:199691
First Author: Zeng Z
Year: 2012
Journal: Nucleic Acids Res
Title: TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.
Volume: 40
Issue: 17
Pages: 8371-80
•
•
•
•
•
Publication
19403927 | J:152931
First Author: van den Bergen JA
Year: 2009
Journal: Biol Reprod
Title: Normalizing gene expression levels in mouse fetal germ cells.
Volume: 81
Issue: 2
Pages: 362-70
•
•
•
•
•
Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom