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Search results 801 to 869 out of 869 for Prnp

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Category: Publication
Type Details Score
Publication
First Author: Liu P
Year: 2015
Journal: PLoS One
Title: Characterization of a Novel Mouse Model of Alzheimer's Disease--Amyloid Pathology and Unique β-Amyloid Oligomer Profile.
Volume: 10
Issue: 5
Pages: e0126317
Publication
First Author: Nuber S
Year: 2008
Journal: J Neurosci
Title: Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.
Volume: 28
Issue: 10
Pages: 2471-84
Publication
First Author: Odeh F
Year: 2011
Journal: Neuroimage
Title: Atlas of transgenic Tet-Off Ca2+/calmodulin-dependent protein kinase II and prion protein promoter activity in the mouse brain.
Volume: 54
Issue: 4
Pages: 2603-11
Publication
First Author: Shi Y
Year: 2021
Journal: Neuron
Title: Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms.
Volume: 109
Issue: 15
Pages: 2413-2426.e7
Publication
First Author: Zhu C
Year: 2016
Journal: J Exp Med
Title: A neuroprotective role for microglia in prion diseases.
Volume: 213
Issue: 6
Pages: 1047-59
Publication  
First Author: Hendrix RD
Year: 2021
Journal: Neurobiol Aging
Title: Alzheimer amyloid-β- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood.
Volume: 97
Pages: 73-88
Publication
First Author: Mok SW
Year: 2012
Journal: J Immunol
Title: B cell-specific S1PR1 deficiency blocks prion dissemination between secondary lymphoid organs.
Volume: 188
Issue: 10
Pages: 5032-40
Publication
First Author: Labbadia J
Year: 2012
Journal: Brain
Title: Suppression of protein aggregation by chaperone modification of high molecular weight complexes.
Volume: 135
Issue: Pt 4
Pages: 1180-96
Publication
First Author: Giliberto L
Year: 2009
Journal: PLoS One
Title: Generation and initial characterization of FDD knock in mice.
Volume: 4
Issue: 11
Pages: e7900
Publication
First Author: Peretti D
Year: 2015
Journal: Nature
Title: RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration.
Volume: 518
Issue: 7538
Pages: 236-9
Publication
First Author: Gilbert R
Year: 2003
Journal: Hum Mol Genet
Title: Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin.
Volume: 12
Issue: 11
Pages: 1287-99
Publication
First Author: Meilandt WJ
Year: 2020
Journal: J Neurosci
Title: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
Volume: 40
Issue: 9
Pages: 1956-1974
Publication
First Author: Lee SH
Year: 2021
Journal: Cell Rep
Title: TREM2-independent oligodendrocyte, astrocyte, and T cell responses to tau and amyloid pathology in mouse models of Alzheimer disease.
Volume: 37
Issue: 13
Pages: 110158
Publication
First Author: Lee SH
Year: 2021
Journal: Neuron
Title: Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology.
Volume: 109
Issue: 8
Pages: 1283-1301.e6
Publication
First Author: Sharkey LM
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly.
Volume: 115
Issue: 44
Pages: E10495-E10504
Publication
First Author: Restelli LM
Year: 2018
Journal: Cell Rep
Title: Neuronal Mitochondrial Dysfunction Activates the Integrated Stress Response to Induce Fibroblast Growth Factor 21.
Volume: 24
Issue: 6
Pages: 1407-1414
Publication
First Author: Lim J
Year: 2008
Journal: J Clin Invest
Title: Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy.
Volume: 118
Issue: 5
Pages: 1877-89
Publication
First Author: Grueninger F
Year: 2010
Journal: Neurobiol Dis
Title: Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice.
Volume: 37
Issue: 2
Pages: 294-306
Publication
First Author: Rhein V
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.
Volume: 106
Issue: 47
Pages: 20057-62
Publication
First Author: Sandoval-Pistorius SS
Year: 2023
Journal: Sci Rep
Title: Ubiquilin-2 regulates pathological alpha-synuclein.
Volume: 13
Issue: 1
Pages: 293
Publication
First Author: Angers RC
Year: 2009
Journal: Emerg Infect Dis
Title: Chronic wasting disease prions in elk antler velvet.
Volume: 15
Issue: 5
Pages: 696-703
Publication
First Author: Ishihara T
Year: 1999
Journal: Neuron
Title: Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform.
Volume: 24
Issue: 3
Pages: 751-62
Publication
First Author: Nakashima H
Year: 2004
Journal: Free Radic Biol Med
Title: Effects of alpha-tocopherol on an animal model of tauopathies.
Volume: 37
Issue: 2
Pages: 176-86
Publication
First Author: Kanata E
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: RNA editing alterations define manifestation of prion diseases.
Volume: 116
Issue: 39
Pages: 19727-19735
Publication
First Author: Harrison PM
Year: 2010
Journal: Genomics
Title: Genomic assessment of the evolution of the prion protein gene family in vertebrates.
Volume: 95
Issue: 5
Pages: 268-77
Publication  
First Author: Bradford BM
Year: 2019
Journal: Front Cell Neurosci
Title: Discrimination of Prion Strain Targeting in the Central Nervous System via Reactive Astrocyte Heterogeneity in CD44 Expression.
Volume: 13
Pages: 411
Publication
First Author: Duque Velásquez C
Year: 2015
Journal: J Virol
Title: Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains.
Volume: 89
Issue: 24
Pages: 12362-73
Publication
First Author: Pedigo CE
Year: 2016
Journal: J Clin Invest
Title: Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury.
Volume: 126
Issue: 9
Pages: 3336-50
Publication
First Author: Wu T
Year: 2019
Journal: Cell Rep
Title: Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
Volume: 28
Issue: 8
Pages: 2111-2123.e6
Publication
First Author: Lacroux C
Year: 2014
Journal: PLoS Pathog
Title: Preclinical detection of variant CJD and BSE prions in blood.
Volume: 10
Issue: 6
Pages: e1004202
Publication
First Author: Xiang X
Year: 2021
Journal: Sci Transl Med
Title: Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases.
Volume: 13
Issue: 615
Pages: eabe5640
Publication
First Author: Pereson S
Year: 2009
Journal: J Pathol
Title: Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models.
Volume: 219
Issue: 2
Pages: 173-81
Publication
First Author: Lewis PA
Year: 2001
Journal: Biochim Biophys Acta
Title: Expression of BRI-amyloid beta peptide fusion proteins: a novel method for specific high-level expression of amyloid beta peptides.
Volume: 1537
Issue: 1
Pages: 58-62
Publication
First Author: Thackray AM
Year: 2004
Journal: J Virol
Title: Accelerated prion disease in the absence of interleukin-10.
Volume: 78
Issue: 24
Pages: 13697-707
Publication  
First Author: Bradford BM
Year: 2017
Journal: J Virol
Title: Oral Prion Disease Pathogenesis Is Impeded in the Specific Absence of CXCR5-Expressing Dendritic Cells.
Volume: 91
Issue: 10
Publication
First Author: Mercer RCC
Year: 2018
Journal: PLoS Pathog
Title: A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles.
Volume: 14
Issue: 1
Pages: e1006826
Publication
First Author: Um JH
Year: 2024
Journal: Theranostics
Title: Selective induction of Rab9-dependent alternative mitophagy using a synthetic derivative of isoquinoline alleviates mitochondrial dysfunction and cognitive deficits in Alzheimer's disease models.
Volume: 14
Issue: 1
Pages: 56-74
Publication
First Author: Kim J
Year: 2009
Journal: Neuron
Title: Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.
Volume: 64
Issue: 5
Pages: 632-44
Publication
First Author: Ishihara T
Year: 2001
Journal: J Neurosci
Title: Attenuated neurodegenerative disease phenotype in tau transgenic mouse lacking neurofilaments.
Volume: 21
Issue: 16
Pages: 6026-35
Publication  
First Author: Sharkey LM
Year: 2020
Journal: Neurobiol Dis
Title: Modeling UBQLN2-mediated neurodegenerative disease in mice: Shared and divergent properties of wild type and mutant UBQLN2 in phase separation, subcellular localization, altered proteostasis pathways, and selective cytotoxicity.
Volume: 143
Pages: 105016
Publication
First Author: Tesseur I
Year: 2006
Journal: J Clin Invest
Title: Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology.
Volume: 116
Issue: 11
Pages: 3060-9
Publication  
First Author: Amadeo A
Year: 2018
Journal: Neuroscience
Title: Postnatal Changes in K+/Cl- Cotransporter-2 Expression in the Forebrain of Mice Bearing a Mutant Nicotinic Subunit Linked to Sleep-Related Epilepsy.
Volume: 386
Pages: 91-107
Publication
First Author: Kim DW
Year: 2022
Journal: Mol Neurodegener
Title: Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes.
Volume: 17
Issue: 1
Pages: 83
Publication
First Author: Bien-Ly N
Year: 2015
Journal: Neuron
Title: Lack of Widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies.
Volume: 88
Issue: 2
Pages: 289-97
Publication
First Author: Litvinchuk A
Year: 2024
Journal: Neuron
Title: Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Volume: 112
Issue: 3
Pages: 384-403.e8
Publication
First Author: Friedman BA
Year: 2018
Journal: Cell Rep
Title: Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models.
Volume: 22
Issue: 3
Pages: 832-847
Publication
First Author: Coomaraswamy J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease.
Volume: 107
Issue: 17
Pages: 7969-74
Publication
First Author: Manfredi I
Year: 2009
Journal: Hum Mol Genet
Title: Expression of mutant beta2 nicotinic receptors during development is crucial for epileptogenesis.
Volume: 18
Issue: 6
Pages: 1075-88
Publication
First Author: Stokin GB
Year: 2008
Journal: Hum Mol Genet
Title: Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides.
Volume: 17
Issue: 22
Pages: 3474-86
Publication
First Author: Kim J
Year: 2007
Journal: J Neurosci
Title: Abeta40 inhibits amyloid deposition in vivo.
Volume: 27
Issue: 3
Pages: 627-33
Publication
First Author: McGowan E
Year: 2005
Journal: Neuron
Title: Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.
Volume: 47
Issue: 2
Pages: 191-199
Publication
First Author: Wahrle SE
Year: 2008
Journal: J Clin Invest
Title: Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.
Volume: 118
Issue: 2
Pages: 671-82
Publication
First Author: Brendel M
Year: 2015
Journal: PLoS One
Title: Cross-sectional comparison of small animal [18F]-florbetaben amyloid-PET between transgenic AD mouse models.
Volume: 10
Issue: 2
Pages: e0116678
Publication
First Author: Kallop DY
Year: 2014
Journal: J Neurosci
Title: A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models.
Volume: 34
Issue: 19
Pages: 6425-37
Publication
First Author: Padilla D
Year: 2011
Journal: PLoS Pathog
Title: Sheep and goat BSE propagate more efficiently than cattle BSE in human PrP transgenic mice.
Volume: 7
Issue: 3
Pages: e1001319
Publication
First Author: Bouybayoune I
Year: 2015
Journal: PLoS Pathog
Title: Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease.
Volume: 11
Issue: 4
Pages: e1004796
Publication
First Author: Dejanovic B
Year: 2022
Journal: Nat Aging
Title: Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models.
Volume: 2
Issue: 9
Pages: 837-850
Publication  
First Author: Li T
Year: 2016
Journal: Nat Commun
Title: The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model.
Volume: 7
Pages: 12082
Publication
First Author: Bourdenx M
Year: 2021
Journal: Cell
Title: Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.
Volume: 184
Issue: 10
Pages: 2696-2714.e25
Publication  
First Author: William CM
Year: 2021
Journal: Neurobiol Dis
Title: Impairment of visual cortical plasticity by amyloid-beta species.
Volume: 154
Pages: 105344
Publication  
First Author: Le Pichon CE
Year: 2017
Journal: Sci Transl Med
Title: Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.
Volume: 9
Issue: 403
Publication
First Author: Savas JN
Year: 2017
Journal: Cell Rep
Title: Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.
Volume: 21
Issue: 9
Pages: 2614-2627
Publication  
First Author: Pozueta J
Year: 2013
Journal: Neuroscience
Title: Synaptic changes in Alzheimer's disease and its models.
Volume: 251
Pages: 51-65
Publication      
First Author: Veterinary Laboratories Agency
Year: 2009
Journal: SID 5 Research Project Final Report, DEFRA Project Code SE1753
Title: Preparation of more sensitive bioassay models for the improved detection, differentiation and diagnosis of the BSE agent
Publication
First Author: Tamgüney G
Year: 2008
Journal: J Gen Virol
Title: Genes contributing to prion pathogenesis.
Volume: 89
Issue: Pt 7
Pages: 1777-1788
Publication
First Author: Lee JE
Year: 2013
Journal: Exp Neurobiol
Title: An update of animal models of Alzheimer disease with a reevaluation of plaque depositions.
Volume: 22
Issue: 2
Pages: 84-95
Publication      
First Author: MouseBookTM
Year: 2005
Journal: Unpublished
Title: Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.
Publication      
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
Publication      
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data