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Search results 1 to 100 out of 543 for Vamp2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Vesicle-associated membrane protein 2 (VAMP2, also known as Synaptobrevin-2) belongs to the VAMP family, which is a group of small, integral membrane proteins of synaptic vesicles that is mostly involved in vesicle fusion. Neurotransmitter release involves the assembly of a heterotrimeric SNARE complex composed of SNAP25, VAMP2 and syntaxin 1 []. VAMP2 plays a specific role in the insulin-dependent recruitment of GLUT4 from its intracellular storage compartment to the cell surface [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Quetglas S
Year: 2002
Journal: EMBO J
Title: Calmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosis.
Volume: 21
Issue: 15
Pages: 3970-9
Publication
First Author: Fritzius T
Year: 2007
Journal: FEBS J
Title: WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta.
Volume: 274
Issue: 6
Pages: 1552-66
Publication
First Author: Martin LB
Year: 1998
Journal: J Biol Chem
Title: Vesicle-associated membrane protein 2 plays a specific role in the insulin-dependent trafficking of the facilitative glucose transporter GLUT4 in 3T3-L1 adipocytes.
Volume: 273
Issue: 3
Pages: 1444-52
Publication
First Author: Hoogstraaten RI
Year: 2020
Journal: Sci Rep
Title: Tetanus insensitive VAMP2 differentially restores synaptic and dense core vesicle fusion in tetanus neurotoxin treated neurons.
Volume: 10
Issue: 1
Pages: 10913
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
Publication
First Author: Kawaguchi T
Year: 2010
Journal: Biochem Biophys Res Commun
Title: The t-SNAREs syntaxin4 and SNAP23 but not v-SNARE VAMP2 are indispensable to tether GLUT4 vesicles at the plasma membrane in adipocyte.
Volume: 391
Issue: 3
Pages: 1336-41
Publication
First Author: Harel A
Year: 2008
Journal: Traffic
Title: Evidence for CALM in directing VAMP2 trafficking.
Volume: 9
Issue: 3
Pages: 417-29
Publication
First Author: Ito H
Year: 2009
Journal: J Neurochem
Title: Sept8 controls the binding of vesicle-associated membrane protein 2 to synaptophysin.
Volume: 108
Issue: 4
Pages: 867-80
Publication
First Author: Wang CC
Year: 2004
Journal: Dev Cell
Title: A role of VAMP8/endobrevin in regulated exocytosis of pancreatic acinar cells.
Volume: 7
Issue: 3
Pages: 359-71
Publication  
First Author: Matveeva EA
Year: 2012
Journal: Neuroscience
Title: Reduction of vesicle-associated membrane protein 2 expression leads to a kindling-resistant phenotype in a murine model of epilepsy.
Volume: 202
Pages: 77-86
Publication
First Author: Choi MG
Year: 2018
Journal: PLoS One
Title: Sequestration of synaptic proteins by alpha-synuclein aggregates leading to neurotoxicity is inhibited by small peptide.
Volume: 13
Issue: 4
Pages: e0195339
Publication    
First Author: Dhara M
Year: 2020
Journal: Elife
Title: Synergistic actions of v-SNARE transmembrane domains and membrane-curvature modifying lipids in neurotransmitter release.
Volume: 9
Publication
First Author: Schwarz Y
Year: 2017
Journal: Nat Neurosci
Title: Astrocytes control synaptic strength by two distinct v-SNARE-dependent release pathways.
Volume: 20
Issue: 11
Pages: 1529-1539
Publication
First Author: Raingo J
Year: 2012
Journal: Nat Neurosci
Title: VAMP4 directs synaptic vesicles to a pool that selectively maintains asynchronous neurotransmission.
Volume: 15
Issue: 5
Pages: 738-45
Publication
First Author: Best D
Year: 2009
Journal: Dev Dyn
Title: Sdmg1 is a component of secretory granules in mouse secretory exocrine tissues.
Volume: 238
Issue: 1
Pages: 223-31
Publication
First Author: Williams D
Year: 2008
Journal: J Cell Biol
Title: Mapping of R-SNARE function at distinct intracellular GLUT4 trafficking steps in adipocytes.
Volume: 180
Issue: 2
Pages: 375-87
Publication
First Author: Nevins AK
Year: 2005
Journal: J Biol Chem
Title: A direct interaction between Cdc42 and vesicle-associated membrane protein 2 regulates SNARE-dependent insulin exocytosis.
Volume: 280
Issue: 3
Pages: 1944-52
Publication
First Author: Ke B
Year: 2007
Journal: J Biol Chem
Title: Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis.
Volume: 282
Issue: 30
Pages: 21786-97
Publication
First Author: Carvalho E
Year: 2004
Journal: J Biol Chem
Title: GLUT4 overexpression or deficiency in adipocytes of transgenic mice alters the composition of GLUT4 vesicles and the subcellular localization of GLUT4 and insulin-responsive aminopeptidase.
Volume: 279
Issue: 20
Pages: 21598-605
Publication
First Author: Oh E
Year: 2009
Journal: Diabetes
Title: Munc18c depletion selectively impairs the sustained phase of insulin release.
Volume: 58
Issue: 5
Pages: 1165-74
Publication
First Author: Jiang H
Year: 2020
Journal: Sci Rep
Title: Live Neuron High-Content Screening Reveals Synaptotoxic Activity in Alzheimer Mouse Model Homogenates.
Volume: 10
Issue: 1
Pages: 3412
Publication
First Author: Dassah M
Year: 2014
Journal: J Cell Sci
Title: Annexin A2 mediates secretion of collagen VI, pulmonary elasticity and apoptosis of bronchial epithelial cells.
Volume: 127
Issue: Pt 4
Pages: 828-44
Publication
First Author: Li SK
Year: 2014
Journal: Diabetologia
Title: Role of vesicle-associated membrane protein 2 in exocytosis of glucagon-like peptide-1 from the murine intestinal L cell.
Volume: 57
Issue: 4
Pages: 809-18
Publication
First Author: Wasik AA
Year: 2012
Journal: Mol Biol Cell
Title: Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking.
Volume: 23
Issue: 17
Pages: 3370-9
Publication
First Author: Procino G
Year: 2008
Journal: J Cell Sci
Title: AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b.
Volume: 121
Issue: Pt 12
Pages: 2097-106
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Deák F
Year: 2004
Journal: Nat Cell Biol
Title: Synaptobrevin is essential for fast synaptic-vesicle endocytosis.
Volume: 6
Issue: 11
Pages: 1102-8
Publication  
First Author: Matti U
Year: 2013
Journal: Nat Commun
Title: Synaptobrevin2 is the v-SNARE required for cytotoxic T-lymphocyte lytic granule fusion.
Volume: 4
Pages: 1439
Publication
First Author: Schoch S
Year: 2001
Journal: Science
Title: SNARE function analyzed in synaptobrevin/VAMP knockout mice.
Volume: 294
Issue: 5544
Pages: 1117-22
Publication
First Author: Hikida T
Year: 2010
Journal: Neuron
Title: Distinct roles of synaptic transmission in direct and indirect striatal pathways to reward and aversive behavior.
Volume: 66
Issue: 6
Pages: 896-907
Publication
First Author: Florian C
Year: 2011
Journal: J Neurosci
Title: Astrocyte-derived adenosine and A1 receptor activity contribute to sleep loss-induced deficits in hippocampal synaptic plasticity and memory in mice.
Volume: 31
Issue: 19
Pages: 6956-62
Publication
First Author: Vilcaes AA
Year: 2021
Journal: Neuron
Title: Interneuronal exchange and functional integration of synaptobrevin via extracellular vesicles.
Volume: 109
Issue: 6
Pages: 971-983.e5
Publication
First Author: Chang CW
Year: 2016
Journal: J Biol Chem
Title: Lipid-anchored Synaptobrevin Provides Little or No Support for Exocytosis or Liposome Fusion.
Volume: 291
Issue: 6
Pages: 2848-57
GXD Expression    
Probe: MGI:6877113
Assay Type: Western blot
Annotation Date: 2022-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689528
Stage: TS28
Assay Id: MGI:6877121
Age: postnatal adult
Image: S2
Specimen Label: Ad
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6877113
Assay Type: Western blot
Annotation Date: 2022-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689523
Stage: TS23
Assay Id: MGI:6877121
Age: embryonic day 15.0
Image: S2
Specimen Label: E15
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3576280
Assay Type: Western blot
Annotation Date: 2005-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:3576319
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3576280
Assay Type: Western blot
Annotation Date: 2005-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:3576319
Age: embryonic day 18.5
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7449281
Assay Type: RT-PCR
Annotation Date: 2023-04-03
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7449318
Age: postnatal adult
Image: 4
Specimen Label: Wild type
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7449281
Assay Type: RT-PCR
Annotation Date: 2023-04-03
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7449318
Age: postnatal adult
Image: 4
Specimen Label: Bloc1sl
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7449281
Assay Type: RT-PCR
Annotation Date: 2023-04-04
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7450709
Age: postnatal adult
Image: 5
Specimen Label: Wild type
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7449281
Assay Type: RT-PCR
Annotation Date: 2023-04-04
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7450709
Age: postnatal adult
Image: 5
Specimen Label: Mecp2 -/y
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4948524
Assay Type: Western blot
Annotation Date: 2006-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842626
Stage: TS26
Assay Id: MGI:3621961
Age: embryonic day 17.5-18.0
Specimen Label: Glands
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4948524
Assay Type: Western blot
Annotation Date: 2006-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842626
Stage: TS26
Assay Id: MGI:3621996
Age: embryonic day 17.5-18.0
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4948524
Assay Type: Western blot
Annotation Date: 2006-05-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1842626
Stage: TS26
Assay Id: MGI:3621996
Age: embryonic day 17.5-18.0
Specimen Label: dko
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:2667812
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:2667825
Age: embryonic day 13.0
Specimen Label: ED 13
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2667812
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:2667825
Age: embryonic day 14.0
Specimen Label: ED 14
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2667812
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:2667825
Age: embryonic day 15.0
Specimen Label: ED 15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2667812
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:2667825
Age: embryonic day 17.0
Specimen Label: ED 17
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2667812
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:2667825
Age: embryonic day 18.0
Specimen Label: ED 18
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2667812
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2667825
Age: postnatal newborn
Specimen Label: New born
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2667812
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2667825
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2687053
Assay Type: Western blot
Annotation Date: 2004-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:2687163
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2687053
Assay Type: Western blot
Annotation Date: 2004-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2687163
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2687053
Assay Type: Western blot
Annotation Date: 2004-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2687163
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2687053
Assay Type: Western blot
Annotation Date: 2004-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2687163
Age: postnatal day 10
Specimen Label: P10
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2687053
Assay Type: Western blot
Annotation Date: 2004-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2687163
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2687053
Assay Type: Western blot
Annotation Date: 2004-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2687163
Age: postnatal adult
Specimen Label: adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4948524
Assay Type: Western blot
Annotation Date: 2006-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3621961
Age: postnatal
Specimen Label: Brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4948524
Assay Type: Western blot
Annotation Date: 2006-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3621973
Age: postnatal
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4948524
Assay Type: Western blot
Annotation Date: 2006-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3621973
Age: postnatal
Specimen Label: ceb ko
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4948524
Assay Type: Western blot
Annotation Date: 2006-05-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3621973
Age: postnatal
Specimen Label: dko
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3789372
Assay Type: Western blot
Annotation Date: 2008-05-28
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3789465
Age: postnatal adult
Image: 4
Specimen Label: H
Specimen Num: 1
GXD Expression  
Probe: MGI:5298929
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3516422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422738
Age: embryonic day 14.5
Image: DC45; Specimen C1373
Specimen Label: DC45; Specimen C1373
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4882220
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4945585
Age: embryonic day 11.5
Image: g01118 E11.5
Note: Expression was region specific and scattered.
Specimen Label: g01118 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4882220
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945585
Age: embryonic day 15.5
Image: g01118 E15.5
Specimen Label: g01118 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5298929
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422738
Age: embryonic day 14.5
Image: DC45; Specimen C1373
Specimen Label: DC45; Specimen C1373
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5298929
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422738
Age: embryonic day 14.5
Image: DC45; Specimen C1373
Specimen Label: DC45; Specimen C1373
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5298929
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2813026
Stage: TS26
Assay Id: MGI:5542917
Age: embryonic day 17.5
Image: GUDMAP:15472
Specimen Label: GUDMAP:15472
Detected: false
Specimen Num: 1