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Search results 101 to 200 out of 389 for Alox5

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Type Details Score
Publication
First Author: Mehrabian M
Year: 2002
Journal: Circ Res
Title: Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice.
Volume: 91
Issue: 2
Pages: 120-6
Publication
First Author: Cheon EC
Year: 2012
Journal: J Gastrointest Surg
Title: Genetic deletion of 5-lipoxygenase increases tumor-infiltrating macrophages in Apc(Δ468) mice.
Volume: 16
Issue: 2
Pages: 389-93
Publication
First Author: Cheon EC
Year: 2011
Journal: Cancer Res
Title: Mast cell 5-lipoxygenase activity promotes intestinal polyposis in APCDelta468 mice.
Volume: 71
Issue: 5
Pages: 1627-36
Publication
First Author: Cao RY
Year: 2007
Journal: Prostaglandins Other Lipid Mediat
Title: Angiotensin II-induced abdominal aortic aneurysm occurs independently of the 5-lipoxygenase pathway in apolipoprotein E-deficient mice.
Volume: 84
Issue: 1-2
Pages: 34-42
Publication  
First Author: Chou VP
Year: 2013
Journal: Neuroscience
Title: Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability.
Volume: 228
Pages: 73-82
Publication
First Author: Narushima S
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: 5-Lipoxygenase-derived lipid mediators are not required for the development of NSAID-induced inflammatory bowel disease in IL-10-/- mice.
Volume: 294
Issue: 2
Pages: G477-88
Publication
First Author: Emerson MR
Year: 2004
Journal: Brain Res
Title: Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase.
Volume: 1021
Issue: 1
Pages: 140-5
Publication
First Author: Yotsumoto S
Year: 2017
Journal: Sci Rep
Title: Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation.
Volume: 7
Issue: 1
Pages: 16026
Publication
First Author: Wang Z
Year: 2014
Journal: J Immunol
Title: Leukotriene B4 enhances the generation of proinflammatory microRNAs to promote MyD88-dependent macrophage activation.
Volume: 192
Issue: 5
Pages: 2349-56
Publication
First Author: Penkert H
Year: 2021
Journal: Cell Rep
Title: Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery.
Volume: 37
Issue: 4
Pages: 109898
Publication
First Author: Ballesteros I
Year: 2014
Journal: J Leukoc Biol
Title: Rosiglitazone-induced CD36 up-regulation resolves inflammation by PPARγ and 5-LO-dependent pathways.
Volume: 95
Issue: 4
Pages: 587-98
Publication
First Author: Wang SS
Year: 2009
Journal: Circ Cardiovasc Genet
Title: Disruption of the aortic elastic lamina and medial calcification share genetic determinants in mice.
Volume: 2
Issue: 6
Pages: 573-82
Publication
First Author: Serezani CH
Year: 2012
Journal: J Immunol
Title: Macrophage dectin-1 expression is controlled by leukotriene B4 via a GM-CSF/PU.1 axis.
Volume: 189
Issue: 2
Pages: 906-15
Publication
First Author: Ibarra-Soria X
Year: 2018
Journal: Nat Cell Biol
Title: Defining murine organogenesis at single-cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation.
Volume: 20
Issue: 2
Pages: 127-134
Publication
First Author: da Silva-Souza HA
Year: 2014
Journal: Biochim Biophys Acta
Title: Inhibitors of the 5-lipoxygenase arachidonic acid pathway induce ATP release and ATP-dependent organic cation transport in macrophages.
Volume: 1838
Issue: 7
Pages: 1967-77
Publication
First Author: Poczobutt JM
Year: 2016
Journal: J Immunol
Title: Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment.
Volume: 196
Issue: 2
Pages: 891-901
Publication
First Author: Serezani CH
Year: 2011
Journal: J Clin Invest
Title: Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression.
Volume: 121
Issue: 2
Pages: 671-82
Publication  
First Author: Li JG
Year: 2017
Journal: Sci Rep
Title: Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype.
Volume: 7
Pages: 46002
Publication
First Author: Swindle EJ
Year: 2007
Journal: J Immunol
Title: FcepsilonRI- and Fcgamma receptor-mediated production of reactive oxygen species by mast cells is lipoxygenase- and cyclooxygenase-dependent and NADPH oxidase-independent.
Volume: 179
Issue: 10
Pages: 7059-71
Publication
First Author: Filgueiras LR
Year: 2015
Journal: Sci Signal
Title: Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes.
Volume: 8
Issue: 361
Pages: ra10
Publication
First Author: Ochkur SI
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: Cys-leukotrienes promote fibrosis in a mouse model of eosinophil-mediated respiratory inflammation.
Volume: 49
Issue: 6
Pages: 1074-84
Publication
First Author: Poeckel D
Year: 2009
Journal: J Biol Chem
Title: Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.
Volume: 284
Issue: 31
Pages: 21077-89
Publication  
First Author: Brandt SL
Year: 2018
Journal: JCI Insight
Title: Excessive localized leukotriene B4 levels dictate poor skin host defense in diabetic mice.
Volume: 3
Issue: 17
Publication
First Author: Brandt SL
Year: 2018
Journal: PLoS Pathog
Title: Macrophage-derived LTB4 promotes abscess formation and clearance of Staphylococcus aureus skin infection in mice.
Volume: 14
Issue: 8
Pages: e1007244
Publication
First Author: Ghazalpour A
Year: 2006
Journal: Genetics
Title: Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice.
Volume: 173
Issue: 2
Pages: 943-51
Publication
First Author: Verri WA Jr
Year: 2007
Journal: Eur J Immunol
Title: IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production.
Volume: 37
Issue: 12
Pages: 3373-80
Publication  
First Author: Subramanian BC
Year: 2020
Journal: J Cell Biol
Title: The LTB4-BLT1 axis regulates actomyosin and β2-integrin dynamics during neutrophil extravasation.
Volume: 219
Issue: 10
Publication
First Author: Chen M
Year: 2014
Journal: Nat Med
Title: Essential role for autophagy in the maintenance of immunological memory against influenza infection.
Volume: 20
Issue: 5
Pages: 503-10
Publication
First Author: Yan Y
Year: 2013
Journal: Immunity
Title: Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.
Volume: 38
Issue: 6
Pages: 1154-63
Publication
First Author: Sorgi CA
Year: 2009
Journal: J Immunol
Title: Histoplasma capsulatum cell wall {beta}-glucan induces lipid body formation through CD18, TLR2, and dectin-1 receptors: correlation with leukotriene B4 generation and role in HIV-1 infection.
Volume: 182
Issue: 7
Pages: 4025-35
Publication
First Author: Du F
Year: 2019
Journal: Clin Cancer Res
Title: Leukotriene Synthesis Is Critical for Medulloblastoma Progression.
Volume: 25
Issue: 21
Pages: 6475-6486
Publication
First Author: Rudhard Y
Year: 2015
Journal: J Neurosci
Title: Identification of 12/15-lipoxygenase as a regulator of axon degeneration through high-content screening.
Volume: 35
Issue: 7
Pages: 2927-41
Publication
First Author: Queto T
Year: 2010
Journal: J Leukoc Biol
Title: Cysteinyl-leukotriene type 1 receptors transduce a critical signal for the up-regulation of eosinophilopoiesis by interleukin-13 and eotaxin in murine bone marrow.
Volume: 87
Issue: 5
Pages: 885-93
Publication
First Author: Rahabi M
Year: 2020
Journal: Cell Rep
Title: Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response.
Volume: 30
Issue: 13
Pages: 4386-4398.e5
Publication
First Author: Patnode ML
Year: 2014
Journal: J Exp Med
Title: Leukotriene B4 amplifies eosinophil accumulation in response to nematodes.
Volume: 211
Issue: 7
Pages: 1281-8
Publication
First Author: Sezin T
Year: 2017
Journal: J Invest Dermatol
Title: The Leukotriene B4 and its Receptor BLT1 Act as Critical Drivers of Neutrophil Recruitment in Murine Bullous Pemphigoid-Like Epidermolysis Bullosa Acquisita.
Volume: 137
Issue: 5
Pages: 1104-1113
Publication
First Author: Sapieha P
Year: 2011
Journal: Sci Transl Med
Title: 5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of ω-3 polyunsaturated fatty acids.
Volume: 3
Issue: 69
Pages: 69ra12
Publication
First Author: Hoggatt J
Year: 2013
Journal: Nature
Title: Differential stem- and progenitor-cell trafficking by prostaglandin E2.
Volume: 495
Issue: 7441
Pages: 365-9
Publication
First Author: von Moltke J
Year: 2017
Journal: J Exp Med
Title: Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s.
Volume: 214
Issue: 1
Pages: 27-37
Publication
First Author: Pernet E
Year: 2023
Journal: Nature
Title: Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE.
Volume: 614
Issue: 7948
Pages: 530-538
Publication
First Author: Yopp AC
Year: 2004
Journal: J Immunol
Title: FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments.
Volume: 173
Issue: 2
Pages: 855-65
Publication
First Author: Cheng LE
Year: 2015
Journal: J Exp Med
Title: IgE-activated basophils regulate eosinophil tissue entry by modulating endothelial function.
Volume: 212
Issue: 4
Pages: 513-24
Publication
First Author: Chen Y
Year: 2008
Journal: Nature
Title: Variations in DNA elucidate molecular networks that cause disease.
Volume: 452
Issue: 7186
Pages: 429-35
Publication
First Author: Sadik CD
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcγR signaling.
Volume: 109
Issue: 46
Pages: E3177-85
Publication
First Author: Mayer-Barber KD
Year: 2014
Journal: Nature
Title: Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk.
Volume: 511
Issue: 7507
Pages: 99-103
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Goulet JL
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Altered inflammatory responses in leukotriene-deficient mice.
Volume: 91
Issue: 26
Pages: 12852-6
Publication
First Author: Chu J
Year: 2011
Journal: Am J Pathol
Title: Pharmacologic blockade of 5-lipoxygenase improves the amyloidotic phenotype of an Alzheimer's disease transgenic mouse model involvement of γ-secretase.
Volume: 178
Issue: 4
Pages: 1762-9
Publication  
First Author: Vagnozzi AN
Year: 2018
Journal: Aging Cell
Title: Brain 5-lipoxygenase over-expression worsens memory, synaptic integrity, and tau pathology in the P301S mice.
Volume: 17
Issue: 1
Publication
First Author: Goulet JL
Year: 2001
Journal: J Immunol
Title: Deficiency of 5-lipoxygenase accelerates renal allograft rejection in mice.
Volume: 167
Issue: 11
Pages: 6631-6
Publication
First Author: Rosen CJ
Year: 2005
Journal: Pediatr Nephrol
Title: Allelic differences in a quantitative trait locus affecting insulin-like growth factor-I impact skeletal acquisition and body composition.
Volume: 20
Issue: 3
Pages: 255-60
Publication
First Author: Jones SM
Year: 2002
Journal: J Biol Chem
Title: Structural and functional criteria reveal a new nuclear import sequence on the 5-lipoxygenase protein.
Volume: 277
Issue: 41
Pages: 38550-6
Publication
First Author: Schwarz K
Year: 2001
Journal: J Biol Chem
Title: Structural basis for lipoxygenase specificity. Conversion of the human leukocyte 5-lipoxygenase to a 15-lipoxygenating enzyme species by site-directed mutagenesis.
Volume: 276
Issue: 1
Pages: 773-9
Publication  
First Author: Zhang YY
Year: 2000
Journal: Biochem J
Title: Analysis of a nucleotide-binding site of 5-lipoxygenase by affinity labelling: binding characteristics and amino acid sequences.
Volume: 351 Pt 3
Pages: 697-707
Publication  
First Author: Funk CD
Year: 1995
Journal: Adv Prostaglandin Thromboxane Leukot Res
Title: Leukotriene-deficient mice generated by targeted disruption of the 5-lipoxygenase gene.
Volume: 23
Pages: 145-50
Publication
First Author: Hennig R
Year: 2005
Journal: Cancer Res
Title: 5-Lipoxygenase, a marker for early pancreatic intraepithelial neoplastic lesions.
Volume: 65
Issue: 14
Pages: 6011-6
Publication
First Author: Lyons MA
Year: 2006
Journal: Circ Res
Title: Arachidonate 5-lipoxygenase variants in atherosclerosis, obesity, and bone traits.
Volume: 98
Issue: 8
Pages: e66
Publication
First Author: Chen H
Year: 2010
Journal: Neuroscience
Title: 5-Lipoxygenase in mouse cerebellar Purkinje cells.
Volume: 171
Issue: 2
Pages: 383-9
Publication
First Author: Schurmann K
Year: 2011
Journal: J Biol Chem
Title: Molecular basis for the reduced catalytic activity of the naturally occurring T560M mutant of human 12/15-lipoxygenase that has been implicated in coronary artery disease.
Volume: 286
Issue: 27
Pages: 23920-7
Publication
First Author: Walther M
Year: 2011
Journal: Arch Biochem Biophys
Title: The N-terminal β-barrel domain of mammalian lipoxygenases including mouse 5-lipoxygenase is not essential for catalytic activity and membrane binding but exhibits regulatory functions.
Volume: 516
Issue: 1
Pages: 1-9
Publication
First Author: Tristão FS
Year: 2013
Journal: Infect Immun
Title: 5-Lipoxygenase activity increases susceptibility to experimental Paracoccidioides brasiliensis infection.
Volume: 81
Issue: 4
Pages: 1256-66
Publication  
First Author: Barbosa-Silva MC
Year: 2022
Journal: Brain Behav Immun
Title: Mice lacking 5-lipoxygenase display motor deficits associated with cortical and hippocampal synapse abnormalities.
Volume: 100
Pages: 183-193
Publication
First Author: Pamplona FA
Year: 2022
Journal: Transl Psychiatry
Title: Age-linked suppression of lipoxin A4 associates with cognitive deficits in mice and humans.
Volume: 12
Issue: 1
Pages: 439
GXD Expression      
Probe: MGI:6256784
Assay Type: RT-PCR
Annotation Date: 2018-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6258647
Age: embryonic day 6.0-7.0
Specimen Label: U46A Gpx4-/-;Alox15-/-
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6256784
Assay Type: RT-PCR
Annotation Date: 2018-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6258647
Age: embryonic day 6.0-7.0
Specimen Label: U46A Gpx4-/+;Alox15-/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6256784
Assay Type: RT-PCR
Annotation Date: 2018-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6258647
Age: embryonic day 6.0-7.0
Specimen Label: U46A Gpx4+/+;Alox15-/-
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7447423
Assay Type: RT-PCR
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914325
Stage: TS25
Assay Id: MGI:7448397
Age: embryonic day 17.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7447423
Assay Type: RT-PCR
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914225
Stage: TS25
Assay Id: MGI:7448397
Age: embryonic day 17.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7447423
Assay Type: RT-PCR
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914325
Stage: TS25
Assay Id: MGI:7448397
Age: embryonic day 17.5
Specimen Label: KI
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447423
Assay Type: RT-PCR
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914225
Stage: TS25
Assay Id: MGI:7448397
Age: embryonic day 17.5
Specimen Label: KI
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447423
Assay Type: RT-PCR
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910623
Stage: TS23
Assay Id: MGI:7448426
Age: embryonic day 15.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7447423
Assay Type: RT-PCR
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910323
Stage: TS23
Assay Id: MGI:7448426
Age: embryonic day 15.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7447423
Assay Type: RT-PCR
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910423
Stage: TS23
Assay Id: MGI:7448426
Age: embryonic day 15.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7447423
Assay Type: RT-PCR
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910623
Stage: TS23
Assay Id: MGI:7448426
Age: embryonic day 15.5
Specimen Label: KI
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447423
Assay Type: RT-PCR
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910323
Stage: TS23
Assay Id: MGI:7448426
Age: embryonic day 15.5
Specimen Label: KI
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447423
Assay Type: RT-PCR
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910423
Stage: TS23
Assay Id: MGI:7448426
Age: embryonic day 15.5
Specimen Label: KI
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4417764
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1646922
Stage: TS22
Assay Id: MGI:5422016
Age: embryonic day 14.5
Specimen Label: EN2086; Specimen N900
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4417764
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647022
Stage: TS22
Assay Id: MGI:5422016
Age: embryonic day 14.5
Specimen Label: EN2086; Specimen N900
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4417764
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:5422016
Age: embryonic day 14.5
Specimen Label: EN2086; Specimen N900
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4417764
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:5422016
Age: embryonic day 14.5
Specimen Label: EN2086; Specimen N900
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4417764
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5422016
Age: embryonic day 14.5
Specimen Label: EN2086; Specimen N900
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4417764
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1777922
Stage: TS22
Assay Id: MGI:5422016
Age: embryonic day 14.5
Specimen Label: EN2086; Specimen N900
Detected: false
Specimen Num: 1