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Search results 301 to 392 out of 392 for Alox5

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Type Details Score
Publication
25802082 | J:284340
First Author: Giannopoulos PF
Year: 2015
Journal: Biol Psychiatry
Title: Pharmacologic inhibition of 5-lipoxygenase improves memory, rescues synaptic dysfunction, and ameliorates tau pathology in a transgenic model of tauopathy.
Volume: 78
Issue: 10
Pages: 693-701
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Publication
10384136 | J:55637
First Author: Goulet JL
Year: 1999
Journal: J Immunol
Title: Deficiency of 5-lipoxygenase abolishes sex-related survival differences in MRL-lpr/lpr mice.
Volume: 163
Issue: 1
Pages: 359-66
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Publication
20876351 | J:165193
First Author: Chen M
Year: 2010
Journal: J Immunol
Title: Joint tissues amplify inflammation and alter their invasive behavior via leukotriene B4 in experimental inflammatory arthritis.
Volume: 185
Issue: 9
Pages: 5503-11
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Publication
16567388 | J:123751
First Author: Chen M
Year: 2006
Journal: J Exp Med
Title: Neutrophil-derived leukotriene B4 is required for inflammatory arthritis.
Volume: 203
Issue: 4
Pages: 837-42
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Publication
9091580 | J:39229
First Author: Byrum RS
Year: 1997
Journal: J Exp Med
Title: Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses.
Volume: 185
Issue: 6
Pages: 1065-75
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Publication
19416808 | J:148535
First Author: Zarini S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Transcellular biosynthesis of cysteinyl leukotrienes in vivo during mouse peritoneal inflammation.
Volume: 106
Issue: 20
Pages: 8296-301
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Publication
23408836 | J:193679
First Author: Wejksza K
Year: 2013
Journal: J Immunol
Title: Cancer-produced metabolites of 5-lipoxygenase induce tumor-evoked regulatory B cells via peroxisome proliferator-activated receptor α.
Volume: 190
Issue: 6
Pages: 2575-84
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Publication
8944751 | J:36801
First Author: Funk CD
Year: 1996
Journal: Biochim Biophys Acta
Title: The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice.
Volume: 1304
Issue: 1
Pages: 65-84
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Publication
9088981 | J:39220
First Author: Edmiston JS
Year: 1997
Journal: Int Immunol
Title: A transforming growth factor-beta regulable RNA-binding protein interacts specifically with germline Ig alpha transcripts.
Volume: 9
Issue: 3
Pages: 427-33
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Publication
16081317 | J:100528
First Author: Lötzer K
Year: 2005
Journal: Biochim Biophys Acta
Title: The 5-lipoxygenase pathway in arterial wall biology and atherosclerosis.
Volume: 1736
Issue: 1
Pages: 30-7
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Publication
19135147 | J:145692
First Author: Yun MR
Year: 2009
Journal: Free Radic Biol Med
Title: 4-Hydroxynonenal enhances CD36 expression on murine macrophages via p38 MAPK-mediated activation of 5-lipoxygenase.
Volume: 46
Issue: 5
Pages: 692-8
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Publication
19965960 | J:176111
First Author: Finkensieper A
Year: 2010
Journal: Cardiovasc Res
Title: The 5-lipoxygenase pathway regulates vasculogenesis in differentiating mouse embryonic stem cells.
Volume: 86
Issue: 1
Pages: 37-44
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Publication
23708969 | J:198733
First Author: Lämmermann T
Year: 2013
Journal: Nature
Title: Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo.
Volume: 498
Issue: 7454
Pages: 371-5
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Publication
24332986 | J:212730
First Author: Joshi YB
Year: 2014
Journal: Neurobiol Aging
Title: Modulation of lipopolysaccharide-induced memory insult, γ-secretase, and neuroinflammation in triple transgenic mice by 5-lipoxygenase.
Volume: 35
Issue: 5
Pages: 1024-31
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Publication
23634895 | J:214888
First Author: Joshi YB
Year: 2013
Journal: Aging Cell
Title: Knockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg mice.
Volume: 12
Issue: 4
Pages: 706-11
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Publication
16698924 | J:110208
First Author: Qiu H
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability.
Volume: 103
Issue: 21
Pages: 8161-6
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Publication
20622882 | J:162390
First Author: Divangahi M
Year: 2010
Journal: Nat Immunol
Title: Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis.
Volume: 11
Issue: 8
Pages: 751-8
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19561612 | J:151654
First Author: Divangahi M
Year: 2009
Journal: Nat Immunol
Title: Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair.
Volume: 10
Issue: 8
Pages: 899-906
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Publication
17404289 | J:122128
First Author: Wielockx B
Year: 2007
Journal: J Immunol
Title: Description and mapping of the resistance of DBA/2 mice to TNF-induced lethal shock.
Volume: 178
Issue: 8
Pages: 5069-75
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Publication
17761955 | J:129968
First Author: Coffey MJ
Year: 2007
Journal: J Leukoc Biol
Title: NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis.
Volume: 82
Issue: 6
Pages: 1585-91
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Publication
23109727 | J:190666
First Author: Lee JM
Year: 2012
Journal: J Immunol
Title: 5-Lipoxygenase mediates RANKL-induced osteoclast formation via the cysteinyl leukotriene receptor 1.
Volume: 189
Issue: 11
Pages: 5284-92
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Publication
25246560 | J:216465
First Author: Fredman G
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway.
Volume: 111
Issue: 40
Pages: 14530-5
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Publication
27060751 | J:248836
 
First Author: Joshi V
Year: 2016
Journal: Arch Biochem Biophys
Title: Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2, lipoxygenase and cyclooxygenase.
Volume: 598
Pages: 28-39
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Publication
22493243 | J:183843
First Author: Yu Z
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice.
Volume: 109
Issue: 17
Pages: 6727-32
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Publication
23951061 | J:205889
First Author: Chu J
Year: 2013
Journal: PLoS One
Title: Zileuton improves memory deficits, amyloid and tau pathology in a mouse model of Alzheimer's disease with plaques and tangles.
Volume: 8
Issue: 8
Pages: e70991
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Publication
22902502 | J:188134
First Author: von Moltke J
Year: 2012
Journal: Nature
Title: Rapid induction of inflammatory lipid mediators by the inflammasome in vivo.
Volume: 490
Issue: 7418
Pages: 107-11
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Publication
22551156 | J:328431
First Author: Sharma P
Year: 2012
Journal: Br J Pharmacol
Title: Epithelium-dependent modulation of responsiveness of airways from caveolin-1 knockout mice is mediated through cyclooxygenase-2 and 5-lipoxygenase.
Volume: 167
Issue: 3
Pages: 548-60
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Publication
25313597 | J:264805
First Author: Brütsch SH
Year: 2015
Journal: Antioxid Redox Signal
Title: Expression of inactive glutathione peroxidase 4 leads to embryonic lethality, and inactivation of the Alox15 gene does not rescue such knock-in mice.
Volume: 22
Issue: 4
Pages: 281-93
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Publication
18645210 | J:142866
First Author: López-Parra M
Year: 2008
Journal: J Lipid Res
Title: Regulatory effects of arachidonate 5-lipoxygenase on hepatic microsomal TG transfer protein activity and VLDL-triglyceride and apoB secretion in obese mice.
Volume: 49
Issue: 12
Pages: 2513-23
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Publication
26432261 | J:233767
First Author: Karnam A
Year: 2015
Journal: Mol Immunol
Title: Sonic hedgehog-responsive lipoxygenases and cyclooxygenase-2 modulate Dectin-1-induced inflammatory cytokines.
Volume: 68
Issue: 2 Pt A
Pages: 280-9
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Publication
7629107 | J:27425
First Author: Chen XS
Year: 1995
Journal: J Biol Chem
Title: cDNA cloning, expression, mutagenesis, intracellular localization, and gene chromosomal assignment of mouse 5-lipoxygenase.
Volume: 270
Issue: 30
Pages: 17993-9
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Publication
15240726 | J:91935
First Author: Goulet JL
Year: 2004
Journal: J Immunol
Title: E-prostanoid-3 receptors mediate the proinflammatory actions of prostaglandin E2 in acute cutaneous inflammation.
Volume: 173
Issue: 2
Pages: 1321-6
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Publication
29467755 | J:337311
 
First Author: Souza-Almeida G
Year: 2018
Journal: Front Immunol
Title: Leptin Mediates In Vivo Neutrophil Migration: Involvement of Tumor Necrosis Factor-Alpha and CXCL1.
Volume: 9
Pages: 111
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Publication
28529998 | J:260077
 
First Author: Miyabe Y
Year: 2017
Journal: Sci Immunol
Title: Complement C5a Receptor is the Key Initiator of Neutrophil Adhesion Igniting Immune Complex-induced Arthritis.
Volume: 2
Issue: 7
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8017775 | J:19332
 
First Author: Funk CD
Year: 1994
Journal: Ann N Y Acad Sci
Title: Targeted gene disruption by homologous recombination. Toward an understanding of specific blood cell functions.
Volume: 714
Pages: 253-8
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Publication
17873277 | J:128345
First Author: Nikolic DM
Year: 2007
Journal: J Biol Chem
Title: Class A scavenger receptor-mediated macrophage adhesion requires coupling of calcium-independent phospholipase A(2) and 12/15-lipoxygenase to Rac and Cdc42 activation.
Volume: 282
Issue: 46
Pages: 33405-11
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Publication
28743859 | J:247822
First Author: Jiang X
Year: 2017
Journal: Nat Commun
Title: Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice.
Volume: 8
Issue: 1
Pages: 128
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Publication
16444258 | J:112604
First Author: Binstadt BA
Year: 2006
Journal: Nat Immunol
Title: Particularities of the vasculature can promote the organ specificity of autoimmune attack.
Volume: 7
Issue: 3
Pages: 284-92
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Publication
23892084 | J:204470
First Author: Inagawa M
Year: 2013
Journal: Mech Dev
Title: Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.
Volume: 130
Issue: 11-12
Pages: 519-31
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Publication
22536403 | J:187204
First Author: Thomas PS
Year: 2012
Journal: PLoS One
Title: Deficient signaling via Alk2 (Acvr1) leads to bicuspid aortic valve development.
Volume: 7
Issue: 4
Pages: e35539
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Publication
29174564 | J:255349
 
First Author: Rauch F
Year: 2018
Journal: Bone
Title: Crispr-Cas9 engineered osteogenesis imperfecta type V leads to severe skeletal deformities and perinatal lethality in mice.
Volume: 107
Pages: 131-142
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Alox5<tm1.1Lky> | MGI:6755140
Name: arachidonate 5-lipoxygenase; targeted mutation 1.1, Richard M Locksley
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Alox5<tm1Fun> | MGI:1857125
Name: arachidonate 5-lipoxygenase; targeted mutation 1, Colin D Funk
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:7495883 | B6(129S4)-Alox5<tm1.1Lky>/J
Attribute String: mutant strain, targeted mutation
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Strain
MGI:2162473 | B6;129S2-Alox5<tm1Fun>/J
Attribute String: targeted mutation, mutant stock
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Strain
MGI:2174127 | B6.129S2-Alox5<tm1Fun>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:2164593 | 129-Alox5<tm1Fun>/J
Attribute String: mutant strain, targeted mutation
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Strain
MGI:3045951 | B6.129S2-Alox5<tm1Fun>
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Alox5/Alox5
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Alox5/Alox5
Background: B6.129S2-Alox5
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Alox5/Alox5
Background: B6.129S2-Alox5/J
Zygosity: hm
Has Mutant Allele: true
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Publication
30258081 | J:268673
First Author: Kumar R
Year: 2018
Journal: Nat Commun
Title: Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers.
Volume: 9
Issue: 1
Pages: 3931
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Publication
37081886 | J:335779
 
First Author: Maier AM
Year: 2023
Journal: Front Immunol
Title: The aryl hydrocarbon receptor regulates lipid mediator production in alveolar macrophages.
Volume: 14
Pages: 1157373
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Publication
23822876 | J:231564
First Author: Tang X
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: Foxa2 regulates leukotrienes to inhibit Th2-mediated pulmonary inflammation.
Volume: 49
Issue: 6
Pages: 960-70
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Publication
28676689 | J:253706
First Author: Onodera T
Year: 2017
Journal: Sci Rep
Title: Eicosapentaenoic acid and 5-HEPE enhance macrophage-mediated Treg induction in mice.
Volume: 7
Issue: 1
Pages: 4560
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Publication
35288557 | J:327329
First Author: Günes Günsel G
Year: 2022
Journal: Nat Commun
Title: The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.
Volume: 13
Issue: 1
Pages: 1303
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Publication
38072238 | J:344169
First Author: Mazi TA
Year: 2024
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Hepatic oxylipin profiles in mouse models of Wilson disease: New insights into early hepatic manifestations.
Volume: 1869
Issue: 2
Pages: 159446
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Publication
27207555 | J:246238
First Author: Elias I
Year: 2016
Journal: Diabetes
Title: ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance.
Volume: 65
Issue: 8
Pages: 2139-50
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Genotype
Genotype
Symbol: Alox5/Alox5 Il13/Il13
Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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