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Search results 101 to 200 out of 730 for Syk

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Type Details Score
Publication
29497423 | J:312231
 
First Author: Samavedam UK
Year: 2018
Journal: Front Immunol
Title: Whole-Genome Expression Profiling in Skin Reveals SYK As a Key Regulator of Inflammation in Experimental Epidermolysis Bullosa Acquisita.
Volume: 9
Pages: 249
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9000133 | J:37676
First Author: Costello PS
Year: 1996
Journal: Oncogene
Title: Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells.
Volume: 13
Issue: 12
Pages: 2595-605
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Publication
22854286 | J:187996
First Author: Cunningham CC
Year: 2012
Journal: Clin Immunol
Title: Osteoarthritis-associated basic calcium phosphate crystals induce pro-inflammatory cytokines and damage-associated molecules via activation of Syk and PI3 kinase.
Volume: 144
Issue: 3
Pages: 228-36
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Publication
20133729 | J:245267
First Author: Uckun FM
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress.
Volume: 107
Issue: 7
Pages: 2902-7
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Publication
15845454 | J:97989
First Author: Rogers NC
Year: 2005
Journal: Immunity
Title: Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins.
Volume: 22
Issue: 4
Pages: 507-17
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Publication
12517949 | J:126305
First Author: Sedlik C
Year: 2003
Journal: J Immunol
Title: A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation.
Volume: 170
Issue: 2
Pages: 846-52
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Publication
30869196 | J:318644
First Author: Liu YS
Year: 2019
Journal: J Cell Mol Med
Title: The pattern-recognition molecule mindin binds integrin Mac-1 to promote macrophage phagocytosis via Syk activation and NF-κB p65 translocation.
Volume: 23
Issue: 5
Pages: 3402-3416
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Publication
25767114 | J:222587
First Author: Manne BK
Year: 2015
Journal: J Biol Chem
Title: Distinct pathways regulate Syk protein activation downstream of immune tyrosine activation motif (ITAM) and hemITAM receptors in platelets.
Volume: 290
Issue: 18
Pages: 11557-68
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Publication
28576735 | J:248994
First Author: Németh T
Year: 2017
Journal: J Invest Dermatol
Title: The Syk Tyrosine Kinase Is Required for Skin Inflammation in an In Vivo Mouse Model of Epidermolysis Bullosa Acquisita.
Volume: 137
Issue: 10
Pages: 2131-2139
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Publication
23962979 | J:219170
First Author: Lin YC
Year: 2013
Journal: Sci Signal
Title: The tyrosine kinase Syk differentially regulates Toll-like receptor signaling downstream of the adaptor molecules TRAF6 and TRAF3.
Volume: 6
Issue: 289
Pages: ra71
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Publication
8626447 | J:31951
First Author: Richards JD
Year: 1996
Journal: J Biol Chem
Title: Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase.
Volume: 271
Issue: 11
Pages: 6458-66
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Publication
16751367 | J:132228
First Author: Sulimenko V
Year: 2006
Journal: J Immunol
Title: Regulation of microtubule formation in activated mast cells by complexes of gamma-tubulin with Fyn and Syk kinases.
Volume: 176
Issue: 12
Pages: 7243-53
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Publication
8082894 | J:20601
First Author: Ku G
Year: 1994
Journal: Immunogenetics
Title: Chromosomal location of the Syk and ZAP-70 tyrosine kinase genes in mice and humans.
Volume: 40
Issue: 4
Pages: 300-2
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Publication
31780731 | J:297910
First Author: Bang BR
Year: 2019
Journal: Sci Rep
Title: The protein tyrosine kinase SYK regulates the alternative p38 activation in liver during acute liver inflammation.
Volume: 9
Issue: 1
Pages: 17838
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Publication
16882714 | J:140446
First Author: Schymeinsky J
Year: 2006
Journal: Blood
Title: The Vav binding site of the non-receptor tyrosine kinase Syk at Tyr 348 is critical for beta2 integrin (CD11/CD18)-mediated neutrophil migration.
Volume: 108
Issue: 12
Pages: 3919-27
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Publication
15048721 | J:131486
First Author: Meade J
Year: 2004
Journal: Eur J Immunol
Title: The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells.
Volume: 34
Issue: 4
Pages: 1102-10
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Publication
15073337 | J:89583
First Author: Mócsai A
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase.
Volume: 101
Issue: 16
Pages: 6158-63
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Publication
17543554 | J:123587
First Author: Zarbock A
Year: 2007
Journal: Immunity
Title: Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1.
Volume: 26
Issue: 6
Pages: 773-83
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Publication
19913447 | J:155296
First Author: Zhang X
Year: 2009
Journal: Immunity
Title: Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils.
Volume: 31
Issue: 5
Pages: 761-71
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Publication
34153467 | J:311077
 
First Author: Trivedi A
Year: 2021
Journal: Neurobiol Dis
Title: Neutrophil-specific deletion of Syk results in recruitment-independent stabilization of the barrier and a long-term improvement in cognitive function after traumatic injury to the developing brain.
Volume: 157
Pages: 105430
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Publication
10799872 | J:124430
First Author: Colucci F
Year: 2000
Journal: J Immunol
Title: A new look at Syk in alpha beta and gamma delta T cell development using chimeric mice with a low competitive hematopoietic environment.
Volume: 164
Issue: 10
Pages: 5140-5
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Publication
12771181 | J:120692
First Author: Sohn HW
Year: 2003
Journal: J Exp Med
Title: Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk.
Volume: 197
Issue: 11
Pages: 1511-24
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Publication
27609517 | J:237276
First Author: Reppschläger K
Year: 2016
Journal: J Biol Chem
Title: TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk.
Volume: 291
Issue: 43
Pages: 22427-22441
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8176201 | J:18037
First Author: Chan AC
Year: 1994
Journal: J Immunol
Title: Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling.
Volume: 152
Issue: 10
Pages: 4758-66
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Publication
17086186 | J:116120
First Author: Mócsai A
Year: 2006
Journal: Nat Immunol
Title: Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs.
Volume: 7
Issue: 12
Pages: 1326-33
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Publication
26195794 | J:226057
First Author: Murata Y
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium.
Volume: 112
Issue: 31
Pages: E4264-71
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19098920 | J:144525
First Author: Hida S
Year: 2009
Journal: Nat Immunol
Title: Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils.
Volume: 10
Issue: 2
Pages: 214-22
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Publication
15143214 | J:90684
First Author: Ohtsuka M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling.
Volume: 101
Issue: 21
Pages: 8126-31
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Publication
22496641 | J:195394
First Author: Lu R
Year: 2012
Journal: PLoS Pathog
Title: CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex.
Volume: 8
Issue: 4
Pages: e1002597
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Publication
19219027 | J:147472
First Author: Sancho D
Year: 2009
Journal: Nature
Title: Identification of a dendritic cell receptor that couples sensing of necrosis to immunity.
Volume: 458
Issue: 7240
Pages: 899-903
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Publication
21245479 | J:170515
First Author: Hesslein DG
Year: 2011
Journal: Blood
Title: Differential requirements for CD45 in NK-cell function reveal distinct roles for Syk-family kinases.
Volume: 117
Issue: 11
Pages: 3087-95
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Publication
20167705 | J:160787
First Author: Mueller H
Year: 2010
Journal: Blood
Title: Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways.
Volume: 115
Issue: 15
Pages: 3118-27
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Publication
- | J:199281
     
First Author: Wang Y
Year: 2013
Journal: MGI Direct Data Submission
Title: Direct data submission for poppy
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20230750 | J:159112
First Author: Böhmer R
Year: 2010
Journal: Dev Cell
Title: Regulation of developmental lymphangiogenesis by Syk(+) leukocytes.
Volume: 18
Issue: 3
Pages: 437-49
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Publication
10689303 | J:60907
First Author: Turner M
Year: 2000
Journal: Immunol Today
Title: Tyrosine kinase SYK: essential functions for immunoreceptor signalling.
Volume: 21
Issue: 3
Pages: 148-54
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Publication
19596610 | J:152810
First Author: Tang B
Year: 2009
Journal: Clin Immunol
Title: T cell receptor signaling induced by an analog peptide of type II collagen requires activation of Syk.
Volume: 133
Issue: 1
Pages: 145-53
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Publication
22914861 | J:187219
First Author: Ozaki N
Year: 2012
Journal: Int Immunol
Title: Syk-dependent signaling pathways in neutrophils and macrophages are indispensable in the pathogenesis of anti-collagen antibody-induced arthritis.
Volume: 24
Issue: 9
Pages: 539-50
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Publication
28919467 | J:269347
 
First Author: Köhler C
Year: 2017
Journal: Brain Res
Title: Distribution of spleen tyrosine kinase and tau phosphorylated at tyrosine 18 in a mouse model of tauopathy and in the human hippocampus.
Volume: 1677
Pages: 1-13
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Publication
27322771 | J:234277
First Author: Ryan J
Year: 2016
Journal: Am J Pathol
Title: Spleen Tyrosine Kinase Signaling Promotes Myeloid Cell Recruitment and Kidney Damage after Renal Ischemia/Reperfusion Injury.
Volume: 186
Issue: 8
Pages: 2032-2042
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Publication
25852057 | J:224651
First Author: Flynn R
Year: 2015
Journal: Blood
Title: Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease.
Volume: 125
Issue: 26
Pages: 4085-94
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Publication
17987119 | J:130402
First Author: Schymeinsky J
Year: 2007
Journal: PLoS One
Title: Syk-mediated translocation of PI3Kdelta to the leading edge controls lamellipodium formation and migration of leukocytes.
Volume: 2
Issue: 11
Pages: e1132
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12531806 | J:83440
First Author: Mócsai A
Year: 2003
Journal: Blood
Title: G-protein-coupled receptor signaling in Syk-deficient neutrophils and mast cells.
Volume: 101
Issue: 10
Pages: 4155-63
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Publication
12234670 | J:79764
First Author: Knobloch J
Year: 2002
Journal: Gene
Title: A novel Syk-family tyrosine kinase from Schistosoma mansoni which is preferentially transcribed in reproductive organs.
Volume: 294
Issue: 1-2
Pages: 87-97
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Publication
17596518 | J:128306
First Author: Le Roux D
Year: 2007
Journal: Mol Biol Cell
Title: Syk-dependent actin dynamics regulate endocytic trafficking and processing of antigens internalized through the B-cell receptor.
Volume: 18
Issue: 9
Pages: 3451-62
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Publication
19124742 | J:143489
First Author: Miller AL
Year: 2009
Journal: J Immunol
Title: Generation of a novel system for studying spleen tyrosine kinase function in macrophages and B cells.
Volume: 182
Issue: 2
Pages: 988-98
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Publication
19096013 | J:148136
First Author: Podolanczuk A
Year: 2009
Journal: Blood
Title: Of mice and men: an open-label pilot study for treatment of immune thrombocytopenic purpura by an inhibitor of Syk.
Volume: 113
Issue: 14
Pages: 3154-60
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Publication
22153076 | J:178917
First Author: Levaot N
Year: 2011
Journal: Cell
Title: Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism.
Volume: 147
Issue: 6
Pages: 1324-39
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24127491 | J:206535
First Author: Stadtmann A
Year: 2013
Journal: J Exp Med
Title: The PSGL-1-L-selectin signaling complex regulates neutrophil adhesion under flow.
Volume: 210
Issue: 11
Pages: 2171-80
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28877763 | J:338512
First Author: Schweig JE
Year: 2017
Journal: Acta Neuropathol Commun
Title: Alzheimer's disease pathological lesions activate the spleen tyrosine kinase.
Volume: 5
Issue: 1
Pages: 69
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Publication
31921172 | J:298502
 
First Author: Doz-Deblauwe É
Year: 2019
Journal: Front Immunol
Title: CR3 Engaged by PGL-I Triggers Syk-Calcineurin-NFATc to Rewire the Innate Immune Response in Leprosy.
Volume: 10
Pages: 2913
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Publication
37520709 | J:339315
First Author: Tsukui D
Year: 2023
Journal: iScience
Title: GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis.
Volume: 26
Issue: 8
Pages: 107293
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27428901 | J:240121
First Author: Wirnsberger G
Year: 2016
Journal: Nat Med
Title: Inhibition of CBLB protects from lethal Candida albicans sepsis.
Volume: 22
Issue: 8
Pages: 915-23
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29272492 | J:328091
First Author: Biagioli M
Year: 2017
Journal: Inflamm Bowel Dis
Title: Genetic and Pharmacological Dissection of the Role of Spleen Tyrosine Kinase (Syk) in Intestinal Inflammation and Immune Dysfunction in Inflammatory Bowel Diseases.
Volume: 24
Issue: 1
Pages: 123-135
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Publication
16943434 | J:112305
First Author: Abtahian F
Year: 2006
Journal: Mol Cell Biol
Title: Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells.
Volume: 26
Issue: 18
Pages: 6936-49
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25382621 | J:222314
First Author: Königsberger S
Year: 2015
Journal: Eur J Immunol
Title: Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms.
Volume: 45
Issue: 2
Pages: 603-11
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Publication
18691974 | J:139490
First Author: Zou W
Year: 2008
Journal: Mol Cell
Title: DAP12 couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk.
Volume: 31
Issue: 3
Pages: 422-31
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17458858 | J:123574
First Author: Slack EC
Year: 2007
Journal: Eur J Immunol
Title: Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan.
Volume: 37
Issue: 6
Pages: 1600-12
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18957693 | J:258167
First Author: Helming L
Year: 2008
Journal: Sci Signal
Title: Essential role of DAP12 signaling in macrophage programming into a fusion-competent state.
Volume: 1
Issue: 43
Pages: ra11
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15711558 | J:97055
First Author: Faccio R
Year: 2005
Journal: Nat Med
Title: Vav3 regulates osteoclast function and bone mass.
Volume: 11
Issue: 3
Pages: 284-90
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30231985 | J:272416
First Author: Malik A
Year: 2018
Journal: Immunity
Title: SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer.
Volume: 49
Issue: 3
Pages: 515-530.e5
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Publication
26297607 | J:266725
First Author: Oosting M
Year: 2015
Journal: Cytokine
Title: Borrelia-induced cytokine production is mediated by spleen tyrosine kinase (Syk) but is Dectin-1 and Dectin-2 independent.
Volume: 76
Issue: 2
Pages: 465-472
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Publication
24185614 | J:209011
First Author: Hara H
Year: 2013
Journal: Nat Immunol
Title: Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity.
Volume: 14
Issue: 12
Pages: 1247-55
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26251216 | J:227729
First Author: Ryan J
Year: 2016
Journal: J Pathol
Title: Myeloid cell-mediated renal injury in rapidly progressive glomerulonephritis depends upon spleen tyrosine kinase.
Volume: 238
Issue: 1
Pages: 10-20
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31324720 | J:281313
First Author: Schweig JE
Year: 2019
Journal: J Biol Chem
Title: Spleen tyrosine kinase (SYK) blocks autophagic Tau degradation in vitro and in vivo.
Volume: 294
Issue: 36
Pages: 13378-13395
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Publication
20363975 | J:160579
First Author: Cash JL
Year: 2010
Journal: J Immunol
Title: Chemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent manner.
Volume: 184
Issue: 9
Pages: 5315-24
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22728826 | J:188422
First Author: Königsberger S
Year: 2012
Journal: EMBO J
Title: Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state.
Volume: 31
Issue: 15
Pages: 3363-74
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Publication
36466913 | J:331991
 
First Author: Costa S
Year: 2022
Journal: Front Immunol
Title: Neutrophils inhibit γδ T cell functions in the imiquimod-induced mouse model of psoriasis.
Volume: 13
Pages: 1049079
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14734724 | J:87653
First Author: Zhong L
Year: 2004
Journal: J Immunol
Title: Zeta-associated protein of 70 kDa (ZAP-70), but not Syk, tyrosine kinase can mediate apoptosis of T cells through the Fas/Fas ligand, caspase-8 and caspase-3 pathways.
Volume: 172
Issue: 3
Pages: 1472-82
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17785780 | J:152057
First Author: Rothfuchs AG
Year: 2007
Journal: J Immunol
Title: Dectin-1 interaction with Mycobacterium tuberculosis leads to enhanced IL-12p40 production by splenic dendritic cells.
Volume: 179
Issue: 6
Pages: 3463-71
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Publication
19703985 | J:152148
First Author: Robinson MJ
Year: 2009
Journal: J Exp Med
Title: Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection.
Volume: 206
Issue: 9
Pages: 2037-51
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Publication
28356391 | J:241854
First Author: Schweighoffer E
Year: 2017
Journal: J Exp Med
Title: TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK.
Volume: 214
Issue: 5
Pages: 1269-1280
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Publication
22078883 | J:178826
First Author: Zanoni I
Year: 2011
Journal: Cell
Title: CD14 controls the LPS-induced endocytosis of Toll-like receptor 4.
Volume: 147
Issue: 4
Pages: 868-80
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29202478 | J:258367
First Author: Muro R
Year: 2018
Journal: J Clin Invest
Title: γδTCR recruits the Syk/PI3K axis to drive proinflammatory differentiation program.
Volume: 128
Issue: 1
Pages: 415-426
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30709742 | J:282472
First Author: Martínez-López M
Year: 2019
Journal: Immunity
Title: Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity.
Volume: 50
Issue: 2
Pages: 446-461.e9
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23521885 | J:195276
First Author: Abram CL
Year: 2013
Journal: Immunity
Title: Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice.
Volume: 38
Issue: 3
Pages: 489-501
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14975240 | J:89716
First Author: Thomas RM
Year: 2004
Journal: Immunity
Title: C-terminal SRC kinase controls acute inflammation and granulocyte adhesion.
Volume: 20
Issue: 2
Pages: 181-91
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33472080 | J:304304
First Author: Liu S
Year: 2021
Journal: Cell Rep
Title: Critical role of Syk-dependent STAT1 activation in innate antiviral immunity.
Volume: 34
Issue: 3
Pages: 108627
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Publication
25630702 | J:217519
First Author: Hobeika E
Year: 2015
Journal: EMBO J
Title: CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk.
Volume: 34
Issue: 7
Pages: 925-39
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Publication
22384232 | J:185297
First Author: Choi SH
Year: 2012
Journal: PLoS One
Title: Spleen tyrosine kinase regulates AP-1 dependent transcriptional response to minimally oxidized LDL.
Volume: 7
Issue: 2
Pages: e32378
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Publication
11262396 | J:166032
First Author: Tartare-Deckert S
Year: 2001
Journal: J Biol Chem
Title: Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte.
Volume: 276
Issue: 24
Pages: 20849-57
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17110603 | J:147937
First Author: Hughan SC
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk.
Volume: 27
Issue: 2
Pages: 422-9
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Publication
17681949 | J:125381
First Author: Abudula A
Year: 2007
Journal: J Biol Chem
Title: SLP-65 signal transduction requires Src homology 2 domain-mediated membrane anchoring and a kinase-independent adaptor function of Syk.
Volume: 282
Issue: 39
Pages: 29059-66
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20335178 | J:163892
First Author: Barbu EA
Year: 2010
Journal: J Biol Chem
Title: The limited contribution of Fyn and Gab2 to the high affinity IgE receptor signaling in mast cells.
Volume: 285
Issue: 21
Pages: 15761-8
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Publication
18465772 | J:136323
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