Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
sheep |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
pig, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
guinea pig |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Allan CM |
Year: |
2017 |
Journal: |
J Lipid Res |
Title: |
Mobility of "HSPG-bound" LPL explains how LPL is able to reach GPIHBP1 on capillaries. |
Volume: |
58 |
Issue: |
1 |
Pages: |
216-225 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sha H |
Year: |
2014 |
Journal: |
Cell Metab |
Title: |
The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism. |
Volume: |
20 |
Issue: |
3 |
Pages: |
458-70 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7276157 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-05-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284227 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7276191 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
S12l control Lpl |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7276157 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-05-10 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284227 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:7276191 |
Age: |
postnatal day 1 |
|
Note: |
Higher levels of expression on layers 5 and 6. |
Specimen Label: |
S12l Fezf2 KO Lpl |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tian GP |
Year: |
2012 |
Journal: |
Biochimie |
Title: |
MicroRNA-467b targets LPL gene in RAW 264.7 macrophages and attenuates lipid accumulation and proinflammatory cytokine secretion. |
Volume: |
94 |
Issue: |
12 |
Pages: |
2749-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hosseini M |
Year: |
2012 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Transgenic expression and genetic variation of Lmf1 affect LPL activity in mice and humans. |
Volume: |
32 |
Issue: |
5 |
Pages: |
1204-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Allan CM |
Year: |
2017 |
Journal: |
J Lipid Res |
Title: |
Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding. |
Volume: |
58 |
Issue: |
7 |
Pages: |
1453-1461 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang HR |
Year: |
2019 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Role of LpL (Lipoprotein Lipase) in Macrophage Polarization In Vitro and In Vivo. |
Volume: |
39 |
Issue: |
10 |
Pages: |
1967-1985 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marshall BA |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Relative hypoglycemia and hyperinsulinemia in mice with heterozygous lipoprotein lipase (LPL) deficiency. Islet LPL regulates insulin secretion. |
Volume: |
274 |
Issue: |
39 |
Pages: |
27426-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang J |
Year: |
2007 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Expression of LPL in endothelial-intact artery results in lipid deposition and vascular cell adhesion molecule-1 upregulation in both LPL and ApoE-deficient mice. |
Volume: |
27 |
Issue: |
1 |
Pages: |
197-203 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7276157 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-05-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3526027 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7276191 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
S12l Layer 6 control Lpl |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7276157 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-05-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525927 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7276191 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
S12l Layer 5 control Lpl |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
464
|
Fragment?: |
false |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6190737 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Lpl |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6190737 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Lpl |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190737 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Lpl |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7276157 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-05-10 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3526027 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7276191 |
Age: |
postnatal day 1 |
|
Note: |
Higher levels of expression on layers 5 and 6. |
Specimen Label: |
S12l Layer 6 Fezf2 KO Lpl |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7276157 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-05-10 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525927 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7276191 |
Age: |
postnatal day 1 |
|
Note: |
Higher levels of expression on layers 5 and 6. |
Specimen Label: |
S12l Layer 5 Fezf2 KO Lpl |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6190737 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Lpl |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6190737 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Lpl |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190737 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Lpl |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190737 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Lpl |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Merkel M |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Inactive lipoprotein lipase (LPL) alone increases selective cholesterol ester uptake in vivo, whereas in the presence of active LPL it also increases triglyceride hydrolysis and whole particle lipoprotein uptake. |
Volume: |
277 |
Issue: |
9 |
Pages: |
7405-11 |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Publication |
First Author: |
Merkel M |
Year: |
1998 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Catalytically inactive lipoprotein lipase expression in muscle of transgenic mice increases very low density lipoprotein uptake: direct evidence that lipoprotein lipase bridging occurs in vivo. |
Volume: |
95 |
Issue: |
23 |
Pages: |
13841-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Savonen R |
Year: |
2015 |
Journal: |
J Lipid Res |
Title: |
The tissue distribution of lipoprotein lipase determines where chylomicrons bind. |
Volume: |
56 |
Issue: |
3 |
Pages: |
588-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Panzenboeck U |
Year: |
1997 |
Journal: |
J Lipid Res |
Title: |
Implications of endogenous and exogenous lipoprotein lipase for the selective uptake of HDL3-associated cholesteryl esters by mouse peritoneal macrophages. |
Volume: |
38 |
Issue: |
2 |
Pages: |
239-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yagyu H |
Year: |
2003 |
Journal: |
J Clin Invest |
Title: |
Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy. |
Volume: |
111 |
Issue: |
3 |
Pages: |
419-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang H |
Year: |
2015 |
Journal: |
Neuroscience |
Title: |
Lipoprotein lipase deficiency leads to α-synuclein aggregation and ubiquitin C-terminal hydrolase L1 reduction. |
Volume: |
290 |
|
Pages: |
1-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu G |
Year: |
2016 |
Journal: |
J Lipid Res |
Title: |
Regulation of plasma lipid homeostasis by hepatic lipoprotein lipase in adult mice. |
Volume: |
57 |
Issue: |
7 |
Pages: |
1155-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Picard A |
Year: |
2014 |
Journal: |
Mol Metab |
Title: |
Hippocampal lipoprotein lipase regulates energy balance in rodents. |
Volume: |
3 |
Issue: |
2 |
Pages: |
167-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jensen DR |
Year: |
1994 |
Journal: |
Biochem J |
Title: |
Regulation of lipoprotein lipase activity and mRNA in the mammary gland of the lactating mouse. |
Volume: |
298 ( Pt 2) |
|
Pages: |
321-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Raisonnier A |
Year: |
1995 |
Journal: |
Comp Biochem Physiol B Biochem Mol Biol |
Title: |
Comparison of the cDNA and amino acid sequences of lipoprotein lipase in eight species. |
Volume: |
111 |
Issue: |
3 |
Pages: |
385-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oka K |
Year: |
1989 |
Journal: |
Biochim Biophys Acta |
Title: |
Expression of lipoprotein lipase gene in combined lipase deficiency. |
Volume: |
1008 |
Issue: |
3 |
Pages: |
351-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao T |
Year: |
2006 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Hemorheological abnormalities in lipoprotein lipase deficient mice with severe hypertriglyceridemia. |
Volume: |
341 |
Issue: |
4 |
Pages: |
1066-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xian X |
Year: |
2009 |
Journal: |
J Neurosci |
Title: |
Presynaptic defects underlying impaired learning and memory function in lipoprotein lipase-deficient mice. |
Volume: |
29 |
Issue: |
14 |
Pages: |
4681-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Augustus A |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression. |
Volume: |
279 |
Issue: |
24 |
Pages: |
25050-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang CL |
Year: |
2018 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Lipoprotein Lipase Deficiency Impairs Bone Marrow Myelopoiesis and Reduces Circulating Monocyte Levels. |
Volume: |
38 |
Issue: |
3 |
Pages: |
509-519 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hua XX |
Year: |
1991 |
Journal: |
Gene |
Title: |
Cloning and characterization of the promoter of the murine lipoprotein lipase-encoding gene: structural and functional analysis. |
Volume: |
107 |
Issue: |
2 |
Pages: |
247-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ross CJ |
Year: |
2004 |
Journal: |
Hum Gene Ther |
Title: |
Long-term correction of murine lipoprotein lipase deficiency with AAV1-mediated gene transfer of the naturally occurring LPL(S447X) beneficial mutation. |
Volume: |
15 |
Issue: |
9 |
Pages: |
906-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Babaev VR |
Year: |
1999 |
Journal: |
J Clin Invest |
Title: |
Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo. |
Volume: |
103 |
Issue: |
12 |
Pages: |
1697-705 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gustafsson M |
Year: |
2007 |
Journal: |
Circ Res |
Title: |
Retention of low-density lipoprotein in atherosclerotic lesions of the mouse: evidence for a role of lipoprotein lipase. |
Volume: |
101 |
Issue: |
8 |
Pages: |
777-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2008 |
Journal: |
Circ Res |
Title: |
Spontaneous atherosclerosis in aged lipoprotein lipase-deficient mice with severe hypertriglyceridemia on a normal chow diet. |
Volume: |
102 |
Issue: |
2 |
Pages: |
250-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takahashi M |
Year: |
2008 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
In vivo arterial lipoprotein lipase expression augments inflammatory responses and impairs vascular dilatation. |
Volume: |
28 |
Issue: |
3 |
Pages: |
455-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lindegaard ML |
Year: |
2005 |
Journal: |
J Lipid Res |
Title: |
Endothelial and lipoprotein lipases in human and mouse placenta. |
Volume: |
46 |
Issue: |
11 |
Pages: |
2339-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Merkel M |
Year: |
1998 |
Journal: |
J Clin Invest |
Title: |
Lipoprotein lipase expression exclusively in liver. A mouse model for metabolism in the neonatal period and during cachexia. |
Volume: |
102 |
Issue: |
5 |
Pages: |
893-901 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao Y |
Year: |
2017 |
Journal: |
Diabetes |
Title: |
Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity. |
Volume: |
66 |
Issue: |
10 |
Pages: |
2555-2563 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang H |
Year: |
2009 |
Journal: |
Diabetes |
Title: |
Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues. |
Volume: |
58 |
Issue: |
1 |
Pages: |
116-24 |
|
•
•
•
•
•
|
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Front Endocrinol (Lausanne) |
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