Type |
Details |
Score |
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
•
•
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Allele |
Name: |
cell division cycle 42; targeted mutation 1, Cord Brakebusch |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
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Allele |
Name: |
myosin VB; targeted mutation 1a, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
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•
•
•
•
•
|
Allele |
Name: |
myosin VB; targeted mutation 1.1, Hans Clevers |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdc42/Cdc42 Tg(Vil1-cre)997Gum/? |
Background: |
involves: C57BL/6J * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Myo5b/Myo5b |
Background: |
C57BL/6N-Myo5b |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Myo5b/Myo5b Tg(Vil1-cre/ERT2)23Syr/? |
Background: |
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * DBA/2 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
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Protein Domain |
Type: |
Domain |
Description: |
Class V myosins are well studied unconventional myosins, represented by three paralogues (Myo5a,b,c) in vertebrates. Their C-terminal cargo binding domains (CBDs) are important for the binding of a diverse set of cargos, including membrane vesicles, organelles, proteins and mRNA. The Myo5-CBDs directly interact with several adaptor proteins [, ]. Myo5b and myo5c are primarily expressed in epithelial cells, and have been implicated as motors involved in recycling endosomes []. |
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•
•
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•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi H |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Structure of a myosin•adaptor complex and pairing by cargo. |
Volume: |
111 |
Issue: |
12 |
Pages: |
E1082-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trybus KM |
Year: |
2008 |
Journal: |
Cell Mol Life Sci |
Title: |
Myosin V from head to tail. |
Volume: |
65 |
Issue: |
9 |
Pages: |
1378-89 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
579
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
722
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng Q |
Year: |
2017 |
Journal: |
J Cell Sci |
Title: |
Disruption of Rab8a and Rab11a causes formation of basolateral microvilli in neonatal enteropathy. |
Volume: |
130 |
Issue: |
15 |
Pages: |
2491-2505 |
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•
•
•
•
•
|
Publication |
First Author: |
Jacobs DT |
Year: |
2009 |
Journal: |
Mol Biol Cell |
Title: |
Myosin Vc is a molecular motor that functions in secretory granule trafficking. |
Volume: |
20 |
Issue: |
21 |
Pages: |
4471-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yao LL |
Year: |
2016 |
Journal: |
J Biol Chem |
Title: |
Identification of the Isoform-specific Interactions between the Tail and the Head of Class V Myosin. |
Volume: |
291 |
Issue: |
15 |
Pages: |
8241-50 |
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•
•
•
•
•
|
Publication |
First Author: |
Wei Z |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Structural basis of cargo recognitions for class V myosins. |
Volume: |
110 |
Issue: |
28 |
Pages: |
11314-9 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1742
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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•
•
•
•
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