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Search results 1 to 65 out of 65 for Tpcn2

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Category: Publication
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Type Details Score
Publication
19557428 | J:175352
First Author: Zong X
Year: 2009
Journal: Pflugers Arch
Title: The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores.
Volume: 458
Issue: 5
Pages: 891-9
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Publication
29750602 | J:284916
First Author: He H
Year: 2018
Journal: Physiol Genomics
Title: Tpcn2 knockout mice have improved insulin sensitivity and are protected against high-fat diet-induced weight gain.
Volume: 50
Issue: 8
Pages: 605-614
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Publication
35929194 | J:329280
First Author: Scotto Rosato A
Year: 2022
Journal: EMBO Mol Med
Title: TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease.
Volume: 14
Issue: 9
Pages: e15377
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Publication
20495006 | J:175340
First Author: Schieder M
Year: 2010
Journal: J Biol Chem
Title: Characterization of two-pore channel 2 (TPCN2)-mediated Ca2+ currents in isolated lysosomes.
Volume: 285
Issue: 28
Pages: 21219-22
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Publication
36641477 | J:332654
First Author: Wang Q
Year: 2023
Journal: Nat Commun
Title: A gain-of-function TPC2 variant R210C increases affinity to PI(3,5)P(2) and causes lysosome acidification and hypopigmentation.
Volume: 14
Issue: 1
Pages: 226
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Publication
25872774 | J:222616
First Author: Ruas M
Year: 2015
Journal: EMBO J
Title: Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells.
Volume: 34
Issue: 13
Pages: 1743-58
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Publication
25236446 | J:216982
First Author: Tsaih SW
Year: 2014
Journal: Genetics
Title: Identification of a novel gene for diabetic traits in rats, mice, and humans.
Volume: 198
Issue: 1
Pages: 17-29
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Publication
25135478 | J:224335
First Author: Ruas M
Year: 2014
Journal: Mol Cell Biol
Title: TPC1 has two variant isoforms, and their removal has different effects on endo-lysosomal functions compared to loss of TPC2.
Volume: 34
Issue: 21
Pages: 3981-92
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Publication
26769314 | J:235705
First Author: Cane MC
Year: 2016
Journal: Cell Calcium
Title: The two pore channel TPC2 is dispensable in pancreatic β-cells for normal Ca²⁺ dynamics and insulin secretion.
Volume: 59
Issue: 1
Pages: 32-40
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Publication
25331892 | J:216665
First Author: Favia A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling.
Volume: 111
Issue: 44
Pages: E4706-15
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Publication
19387438 | J:149472
First Author: Calcraft PJ
Year: 2009
Journal: Nature
Title: NAADP mobilizes calcium from acidic organelles through two-pore channels.
Volume: 459
Issue: 7246
Pages: 596-600
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Publication
20547763 | J:165894
First Author: Tugba Durlu-Kandilci N
Year: 2010
Journal: J Biol Chem
Title: TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscle.
Volume: 285
Issue: 32
Pages: 24925-32
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Publication
32167471 | J:306599
   
First Author: Gerndt S
Year: 2020
Journal: Elife
Title: Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.
Volume: 9
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Publication
25480788 | J:237440
First Author: Lin PH
Year: 2015
Journal: J Biol Chem
Title: Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signaling.
Volume: 290
Issue: 6
Pages: 3377-89
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Publication
27231233 | J:328828
 
First Author: Bellono NW
Year: 2016
Journal: Sci Rep
Title: A melanosomal two-pore sodium channel regulates pigmentation.
Volume: 6
Pages: 26570
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Publication
24776928 | J:306709
First Author: Cang C
Year: 2014
Journal: Nat Chem Biol
Title: The voltage-gated sodium channel TPC1 confers endolysosomal excitability.
Volume: 10
Issue: 6
Pages: 463-9
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Publication
25722412 | J:306587
First Author: Sakurai Y
Year: 2015
Journal: Science
Title: Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment.
Volume: 347
Issue: 6225
Pages: 995-8
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Publication
29563152 | J:262211
First Author: Hamilton A
Year: 2018
Journal: Diabetes
Title: Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells.
Volume: 67
Issue: 6
Pages: 1128-1139
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Publication
26152717 | J:336382
First Author: Arredouani A
Year: 2015
Journal: J Biol Chem
Title: Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells.
Volume: 290
Issue: 35
Pages: 21376-92
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Publication
25545384 | J:221929
First Author: Lear PV
Year: 2015
Journal: Endocrinology
Title: Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissue.
Volume: 156
Issue: 3
Pages: 975-86
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Publication
35885013 | J:338463
 
First Author: Royer J
Year: 2022
Journal: Biomedicines
Title: Unexpected Motherhood-Triggered Hearing Loss in the Two-Pore Channel (TPC) Mutant Mouse.
Volume: 10
Issue: 7
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Publication
26438825 | J:227419
First Author: Capel RA
Year: 2015
Journal: J Biol Chem
Title: Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart.
Volume: 290
Issue: 50
Pages: 30087-98
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Publication
30482851 | J:284400
 
First Author: Foster WJ
Year: 2018
Journal: Sci Signal
Title: Hippocampal mGluR1-dependent long-term potentiation requires NAADP-mediated acidic store Ca2+ signaling.
Volume: 11
Issue: 558
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Publication
25144390 | J:225206
 
First Author: Grimm C
Year: 2014
Journal: Nat Commun
Title: High susceptibility to fatty liver disease in two-pore channel 2-deficient mice.
Volume: 5
Pages: 4699
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Publication
23063126 | J:189070
First Author: Wang X
Year: 2012
Journal: Cell
Title: TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes.
Volume: 151
Issue: 2
Pages: 372-83
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Publication
23394946 | J:193600
First Author: Cang C
Year: 2013
Journal: Cell
Title: mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state.
Volume: 152
Issue: 4
Pages: 778-790
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Publication
26571400 | J:229827
First Author: Shigeto M
Year: 2015
Journal: J Clin Invest
Title: GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.
Volume: 125
Issue: 12
Pages: 4714-28
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Publication
31806695 | J:285199
First Author: Freeman SA
Year: 2020
Journal: Science
Title: Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance.
Volume: 367
Issue: 6475
Pages: 301-305
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Publication
32510172 | J:336348
First Author: Davis LC
Year: 2020
Journal: EMBO J
Title: NAADP-regulated two-pore channels drive phagocytosis through endo-lysosomal Ca(2+) nanodomains, calcineurin and dynamin.
Volume: 39
Issue: 14
Pages: e104058
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Publication
23103503 | J:206556
 
First Author: Neely Kayala KM
Year: 2012
Journal: Brain Res
Title: Presenilin-null cells have altered two-pore calcium channel expression and lysosomal calcium: implications for lysosomal function.
Volume: 1489
Pages: 8-16
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Publication
36744839 | J:334504
 
First Author: Kounoupa Z
Year: 2023
Journal: J Cell Sci
Title: Rac1 and Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons.
Volume: 136
Issue: 6
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Publication
30563862 | J:284476
 
First Author: Diercks BP
Year: 2018
Journal: Sci Signal
Title: ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.
Volume: 11
Issue: 561
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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