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Search results 1 to 1 out of 1 for Fam3d

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
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Type Details Score
Protein Domain
IPR039240 | FAM3D
Type: Family
Description: FAM3D inhibits glucagon secretion via MKP1-dependent suppression of ERK1/2 signaling. As dysregulated glucagon secretion is a characteristic of type 2 diabetes, FAM3D could have a therapeutic potential []. FAM3D is constitutively expressed in the gastrointestinal tract []and could play a role in gastrointestinal homeostasis and inflammation through its receptors FPR1 and FPR2 [].
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