|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 153 for Crb2

<< First    < Previous  |  Next >    Last >>
0.046s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Alves CH
Year: 2014
Journal: Hum Mol Genet
Title: Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa.
Volume: 23
Issue: 13
Pages: 3384-401
Publication  
First Author: Paniagua AE
Year: 2015
Journal: Sci Rep
Title: CRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium.
Volume: 5
Pages: 14504
Publication
First Author: Pellissier LP
Year: 2014
Journal: Hum Mol Genet
Title: CRB2 acts as a modifying factor of CRB1-related retinal dystrophies in mice.
Volume: 23
Issue: 14
Pages: 3759-71
Publication  
First Author: Alves CH
Year: 2019
Journal: Int J Mol Sci
Title: CRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast Sensitivity.
Volume: 20
Issue: 17
Publication
First Author: Pellissier LP
Year: 2013
Journal: PLoS Genet
Title: Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis.
Volume: 9
Issue: 12
Pages: e1003976
Publication
First Author: Alves CH
Year: 2013
Journal: PLoS One
Title: Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background.
Volume: 8
Issue: 12
Pages: e82532
Publication
First Author: Quinn PM
Year: 2018
Journal: Hum Mol Genet
Title: CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function.
Volume: 27
Issue: 18
Pages: 3137-3153
Publication
First Author: Dolón JF
Year: 2018
Journal: Sci Rep
Title: Expression and localization of the polarity protein CRB2 in adult mouse brain: a comparison with the CRB1rd8 mutant mouse model.
Volume: 8
Issue: 1
Pages: 11652
Publication
First Author: Alves CH
Year: 2013
Journal: Hum Mol Genet
Title: Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.
Volume: 22
Issue: 1
Pages: 35-50
Publication
First Author: Möller-Kerutt A
Year: 2021
Journal: J Am Soc Nephrol
Title: Crumbs2 Is an Essential Slit Diaphragm Protein of the Renal Filtration Barrier.
Volume: 32
Issue: 5
Pages: 1053-1070
Publication
First Author: Hamano S
Year: 2018
Journal: PLoS One
Title: Association of crumbs homolog-2 with mTORC1 in developing podocyte.
Volume: 13
Issue: 8
Pages: e0202400
Publication
First Author: Son S
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Crumbs proteins regulate layered retinal vascular development required for vision.
Volume: 521
Issue: 4
Pages: 939-946
Publication
First Author: Xiao Z
Year: 2011
Journal: Dev Dyn
Title: Deficiency in Crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice.
Volume: 240
Issue: 12
Pages: 2646-56
Publication
First Author: Ramkumar N
Year: 2016
Journal: Nat Cell Biol
Title: Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation.
Volume: 18
Issue: 12
Pages: 1281-1291
Publication  
First Author: Cho SH
Year: 2024
Journal: Dev Biol
Title: Perturbed cell cycle phase-dependent positioning and nuclear migration of retinal progenitors along the apico-basal axis underlie global retinal disorganization in the LCA8-like mouse model.
Volume: 517
Pages: 39-54
Publication
First Author: Tait CM
Year: 2020
Journal: PLoS Biol
Title: Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal.
Volume: 18
Issue: 3
Pages: e3000470
Publication  
First Author: Dudok JJ
Year: 2016
Journal: Neurosci Res
Title: Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon.
Volume: 108
Pages: 12-23
Publication
First Author: Cho SH
Year: 2012
Journal: Hum Mol Genet
Title: Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis.
Volume: 21
Issue: 12
Pages: 2663-76
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:6192120
Assay Type: RT-PCR
Annotation Date: 2018-08-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6192438
Age: embryonic day 1.0
Image: S1
Specimen Label: 2c
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6192120
Assay Type: RT-PCR
Annotation Date: 2018-08-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:6192438
Age: embryonic day 2.0
Image: S1
Specimen Label: 8c
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6192120
Assay Type: RT-PCR
Annotation Date: 2018-08-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:6192438
Age: embryonic day 0.5
Image: S1
Specimen Label: Zy
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6192120
Assay Type: RT-PCR
Annotation Date: 2018-08-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:6192438
Age: embryonic day 3.5
Image: S1
Specimen Label: Bl
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7506762
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7506776
Age: embryonic day 18.5
Note: Expression was detected in the subapical region.
Specimen Label: 6A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7506762
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716826
Stage: TS26
Assay Id: MGI:7506776
Age: embryonic day 18.5
Note: Some slight signal may be due to cross-reaction of the antibody.
Specimen Label: 6B
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:7506762
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7506776
Age: embryonic day 12.5
Note: Expression was detected in the subapical region.
Specimen Label: S1J
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7506762
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-13
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1716820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7506776
Age: embryonic day 12.5
Specimen Label: S1M
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7438259
Age: embryonic day 15.5
Image: 5B
Note: Expressed in outer limiting membrane in the apical surface.
Specimen Label: 5B
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7438259
Age: embryonic day 15.5
Image: 5D
Note: Abrupt discontinuation of primitive outer limiting membrane at the apical surface.
Specimen Label: 5D
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7438259
Age: embryonic day 16.5
Image: 5E
Note: The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression.
Specimen Label: 5E
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2007-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:3721259
Age: embryonic day 7.75
Image: 4K
Note: Expression was apically concentrated in the epiblast.
Specimen Label: 4K
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2007-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:3721259
Age: embryonic day 7.75
Image: 4L
Note: Expression was apically concentrated in the epiblast as in wild type.
Specimen Label: 4L
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2007-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3721259
Age: embryonic day 8.5
Image: 6E
Note: Expression was restricted to the apical surface.
Specimen Label: 6E
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2007-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3721259
Age: embryonic day 8.5
Image: 6F
Note: Expression was restricted to the apical surface as in wild type.
Specimen Label: 6F
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2007-09-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1607111
Stage: TS11
Assay Id: MGI:3721259
Age: embryonic day 7.75
Image: 4K
Note: Expression was absent from involuting mesoderm.
Specimen Label: 4K
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2007-09-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1607111
Stage: TS11
Assay Id: MGI:3721259
Age: embryonic day 7.75
Image: 4L
Note: Expression was absent from involuting mesoderm as in wild type.
Specimen Label: 4L
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:7434426
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1779024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7435350
Age: embryonic day 16.5
Image: 8G
Note: Expressed in the apical junctional complex of neuroepithelium at the ventricular surface continuously.
Specimen Label: 8G
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7434426
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1779024
Stage: TS24
Assay Id: MGI:7435350
Age: embryonic day 16.5
Image: 8H
Specimen Label: 8H
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:7434426
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1779022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7435350
Age: embryonic day 14.5
Image: 8K
Note: Expressed in the apical junctional complex of neuroepithelium at the ventricular surface continuously.
Specimen Label: 8K
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:7434426
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1779022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7435350
Age: embryonic day 14.5
Image: 8L
Note: Loss of apical localization of Crbs correlated with the Yap1-reduced area.
Specimen Label: 8L
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:7434426
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1779024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7435352
Age: embryonic day 16.5
Image: S7C/C'
Note: Expressed in the apical junctional complex of neuroepithelium at the ventricular surface continuously.
Specimen Label: S7C/C'
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7434426
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1779024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7435352
Age: embryonic day 16.5
Image: S7D/D'
Note: Not expressed at the ventricular surface in some areas.
Specimen Label: S7D/D'
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7506762
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717119
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7506776
Age: embryonic day 11.5
Note: Expression was detected in the apical neuroepithelial layer.
Specimen Label: S1A
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:7506762
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717119
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7506776
Age: embryonic day 11.5
Note: Expression was detected in the apical neuroepithelial layer in the knockout.
Specimen Label: S1D
Detected: true
Specimen Num: 4
Publication
First Author: Cho SH
Year: 2019
Journal: Dev Biol
Title: Targeted deletion of Crb1/Crb2 in the optic vesicle models key features of leber congenital amaurosis 8.
Volume: 453
Issue: 2
Pages: 141-154
Publication
First Author: van Rossum AG
Year: 2006
Journal: Hum Mol Genet
Title: Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells.
Volume: 15
Issue: 18
Pages: 2659-72
Publication
First Author: Gosens I
Year: 2007
Journal: Exp Cell Res
Title: FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex.
Volume: 313
Issue: 19
Pages: 3959-70
Publication  
First Author: Jiang X
Year: 2018
Journal: Gene Expr Patterns
Title: Asymmetric distribution of CRUMBS polarity complex proteins from compacted 8-cell to blastocyst stage during mouse preimplantation development.
Volume: 27
Pages: 93-98
Publication
First Author: Augustin M
Year: 2005
Journal: Mamm Genome
Title: Efficient and fast targeted production of murine models based on ENU mutagenesis.
Volume: 16
Issue: 6
Pages: 405-13
Publication
First Author: Kim JY
Year: 2015
Journal: Gene Expr Patterns
Title: Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye.
Volume: 17
Issue: 1
Pages: 31-7
Publication
First Author: Ramkumar N
Year: 2015
Journal: PLoS Genet
Title: Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2.
Volume: 11
Issue: 10
Pages: e1005551
Publication
First Author: Srinivasan K
Year: 2008
Journal: Development
Title: MALS-3 regulates polarity and early neurogenesis in the developing cerebral cortex.
Volume: 135
Issue: 10
Pages: 1781-90
Publication
First Author: Szymaniak AD
Year: 2015
Journal: Dev Cell
Title: Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap.
Volume: 34
Issue: 3
Pages: 283-96
Publication
First Author: Lee JD
Year: 2007
Journal: Development
Title: The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo.
Volume: 134
Issue: 11
Pages: 2007-16
Publication  
First Author: Charrier LE
Year: 2015
Journal: Sci Rep
Title: Mouse Crumbs3 sustains epithelial tissue morphogenesis in vivo.
Volume: 5
Pages: 17699
Publication
First Author: Kim S
Year: 2010
Journal: Neuron
Title: The apical complex couples cell fate and cell survival to cerebral cortical development.
Volume: 66
Issue: 1
Pages: 69-84
Publication
First Author: Grego-Bessa J
Year: 2023
Journal: Circ Res
Title: Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development.
Volume: 133
Issue: 11
Pages: 927-943
Publication
First Author: Hughes LJ
Year: 2020
Journal: Dev Biol
Title: Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation.
Volume: 457
Issue: 1
Pages: 150-162
Publication
First Author: Dudok JJ
Year: 2013
Journal: J Neurosci
Title: MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex.
Volume: 33
Issue: 19
Pages: 8518-27
Publication
First Author: Grego-Bessa J
Year: 2015
Journal: Development
Title: Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains.
Volume: 142
Issue: 7
Pages: 1305-14
Publication
First Author: Kim JY
Year: 2016
Journal: Dev Biol
Title: Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye.
Volume: 419
Issue: 2
Pages: 336-347
Publication
First Author: Whiteman EL
Year: 2014
Journal: Mol Cell Biol
Title: Crumbs3 is essential for proper epithelial development and viability.
Volume: 34
Issue: 1
Pages: 43-56
Publication
First Author: Perez-Garcia V
Year: 2018
Journal: Nature
Title: Placentation defects are highly prevalent in embryonic lethal mouse mutants.
Volume: 555
Issue: 7697
Pages: 463-468
Publication      
First Author: Centre for Modeling Human Disease
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto
Publication
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
Publication  
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database