Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_05 |
|
Specimen Label: |
euxassay_009628_05 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_06 |
|
Specimen Label: |
euxassay_009628_06 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_07 |
|
Specimen Label: |
euxassay_009628_07 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_08 |
|
Specimen Label: |
euxassay_009628_08 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_16 |
|
Specimen Label: |
euxassay_009628_16 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_17 |
|
Specimen Label: |
euxassay_009628_17 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_18 |
|
Specimen Label: |
euxassay_009628_18 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_19 |
|
Specimen Label: |
euxassay_009628_19 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_20 |
|
Specimen Label: |
euxassay_009628_20 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_21 |
|
Specimen Label: |
euxassay_009628_21 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_22 |
|
Specimen Label: |
euxassay_009628_22 |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1715823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_13 |
|
Specimen Label: |
euxassay_009628_13 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1715823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_14 |
|
Specimen Label: |
euxassay_009628_14 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_03 |
|
Specimen Label: |
euxassay_009628_03 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_04 |
|
Specimen Label: |
euxassay_009628_04 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_05 |
|
Specimen Label: |
euxassay_009628_05 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_19 |
|
Specimen Label: |
euxassay_009628_19 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_20 |
|
Specimen Label: |
euxassay_009628_20 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_21 |
|
Specimen Label: |
euxassay_009628_21 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000683 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2760523 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541243 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6891 |
|
Specimen Label: |
GUDMAP:6891 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000683 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2760523 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541243 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6892 |
|
Specimen Label: |
GUDMAP:6892 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_06 |
|
Specimen Label: |
euxassay_009628_06 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_07 |
|
Specimen Label: |
euxassay_009628_07 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_16 |
|
Specimen Label: |
euxassay_009628_16 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_17 |
|
Specimen Label: |
euxassay_009628_17 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000683 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2852723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541243 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6891 |
|
Specimen Label: |
GUDMAP:6891 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000683 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2852723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541243 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6892 |
|
Specimen Label: |
GUDMAP:6892 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000683 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2874723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541243 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6891 |
|
Specimen Label: |
GUDMAP:6891 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_07 |
|
Specimen Label: |
euxassay_009628_07 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_08 |
|
Specimen Label: |
euxassay_009628_08 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_09 |
|
Specimen Label: |
euxassay_009628_09 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_10 |
|
Specimen Label: |
euxassay_009628_10 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_11 |
|
Specimen Label: |
euxassay_009628_11 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_12 |
|
Specimen Label: |
euxassay_009628_12 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_13 |
|
Specimen Label: |
euxassay_009628_13 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_14 |
|
Specimen Label: |
euxassay_009628_14 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_15 |
|
Specimen Label: |
euxassay_009628_15 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423898 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827530 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009628_16 |
|
Specimen Label: |
euxassay_009628_16 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000683 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2850023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541243 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6891 |
|
Specimen Label: |
GUDMAP:6891 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000683 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2850023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541243 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6892 |
|
Specimen Label: |
GUDMAP:6892 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000683 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:1796223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541243 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6891 |
|
Specimen Label: |
GUDMAP:6891 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kubosaki A |
Year: |
2006 |
Journal: |
Endocrinology |
Title: |
Disruption of the transmembrane dense core vesicle proteins IA-2 and IA-2beta causes female infertility. |
Volume: |
147 |
Issue: |
2 |
Pages: |
811-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SM |
Year: |
2009 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Dense-core vesicle proteins IA-2 and IA-2{beta} affect renin synthesis and secretion through the {beta}-adrenergic pathway. |
Volume: |
296 |
Issue: |
2 |
Pages: |
F382-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishimura T |
Year: |
2009 |
Journal: |
Neuroscience |
Title: |
Disturbances in the secretion of neurotransmitters in IA-2/IA-2beta null mice: changes in behavior, learning and lifespan. |
Volume: |
159 |
Issue: |
2 |
Pages: |
427-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cai T |
Year: |
2011 |
Journal: |
Diabetologia |
Title: |
Deletion of Ia-2 and/or Ia-2β in mice decreases insulin secretion by reducing the number of dense core vesicles. |
Volume: |
54 |
Issue: |
9 |
Pages: |
2347-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carmona GN |
Year: |
2014 |
Journal: |
Neuroscience |
Title: |
The dense core vesicle protein IA-2, but not IA-2β, is required for active avoidance learning. |
Volume: |
269 |
|
Pages: |
35-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mandemakers W |
Year: |
2013 |
Journal: |
Diabetologia |
Title: |
Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2 β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain. |
Volume: |
56 |
Issue: |
7 |
Pages: |
1547-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu H |
Year: |
2015 |
Journal: |
Diabetologia |
Title: |
The Ia-2β intronic miRNA, miR-153, is a negative regulator of insulin and dopamine secretion through its effect on the Cacna1c gene in mice. |
Volume: |
58 |
Issue: |
10 |
Pages: |
2298-306 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kubosaki A |
Year: |
2005 |
Journal: |
Diabetes |
Title: |
Dense core vesicle proteins IA-2 and IA-2beta: metabolic alterations in double knockout mice. |
Volume: |
54 Suppl 2 |
|
Pages: |
S46-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cai T |
Year: |
2001 |
Journal: |
Diabetologia |
Title: |
The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish. |
Volume: |
44 |
Issue: |
1 |
Pages: |
81-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
van den Maagdenberg AM |
Year: |
1998 |
Journal: |
Cytogenet Cell Genet |
Title: |
Assignment of Ptprn2, the gene encoding receptor-type protein tyrosine phosphatase IA-2beta, a major autoantigen in insulin-dependent diabetes mellitus, to mouse chromosome region 12F. |
Volume: |
82 |
Issue: |
3-4 |
Pages: |
153-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Henquin JC |
Year: |
2008 |
Journal: |
J Endocrinol |
Title: |
Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta. |
Volume: |
196 |
Issue: |
3 |
Pages: |
573-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kubosaki A |
Year: |
2004 |
Journal: |
Diabetologia |
Title: |
IA-2 is not required for the development of diabetes in NOD mice. |
Volume: |
47 |
Issue: |
1 |
Pages: |
149-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gross S |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Multimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activity. |
Volume: |
277 |
Issue: |
50 |
Pages: |
48139-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Punia S |
Year: |
2012 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Disruption of gene expression rhythms in mice lacking secretory vesicle proteins IA-2 and IA-2β. |
Volume: |
303 |
Issue: |
6 |
Pages: |
E762-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leiter EH |
Year: |
1997 |
Journal: |
Mamm Genome |
Title: |
Mapping to chromosomes 1 and 12 of mouse homologs of human protein tyrosine phosphatase, receptor-type, related genes encoding pancreatic beta cell autoantigens. |
Volume: |
8 |
Issue: |
12 |
Pages: |
949-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fischl AM |
Year: |
2014 |
Journal: |
Chem Senses |
Title: |
Activity-dependent genes in mouse olfactory sensory neurons. |
Volume: |
39 |
Issue: |
5 |
Pages: |
439-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ehringer MA |
Year: |
2002 |
Journal: |
Alcohol Clin Exp Res |
Title: |
Fine mapping of polymorphic alcohol-related quantitative trait loci candidate genes using interval-specific congenic recombinant mice. |
Volume: |
26 |
Issue: |
11 |
Pages: |
1603-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lachke SA |
Year: |
2012 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
iSyTE: integrated Systems Tool for Eye gene discovery. |
Volume: |
53 |
Issue: |
3 |
Pages: |
1617-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hendriks W |
Year: |
1995 |
Journal: |
Biochem J |
Title: |
A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain. |
Volume: |
305 ( Pt 2) |
|
Pages: |
499-504 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shah K |
Year: |
2020 |
Journal: |
J Mol Cell Biol |
Title: |
A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells. |
Volume: |
12 |
Issue: |
1 |
Pages: |
4-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ehringer MA |
Year: |
2001 |
Journal: |
Mamm Genome |
Title: |
High-throughput sequence identification of gene coding variants within alcohol-related QTLs. |
Volume: |
12 |
Issue: |
8 |
Pages: |
657-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Memic F |
Year: |
2018 |
Journal: |
Gastroenterology |
Title: |
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. |
Volume: |
154 |
Issue: |
3 |
Pages: |
624-636 |
|
•
•
•
•
•
|
Publication |
First Author: |
NIH Mouse Knockout Inventory |
Year: |
2004 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the NIH Mouse Knockout Inventory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Allele |
Name: |
protein tyrosine phosphatase receptor type N; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Homologous_superfamily |
Description: |
IA-2 (also known as PTPRN or ICA512) and phogrin (also known as PTPRN2, IA-2b, IAR or ICAAR) are homologous protein-tyrosine phosphatase (PTP) receptors. They have a signal peptide, an ectodomain, a single-pass transmembrane region, and a single intracellular PTP domain. Processing of pro IA-2 by furin-like hormone convertases produces mature IA-2, which lacks the signal peptide and an adjacent fragment (residues 1-448). Upon exocytosis, the cytoplasmic domain of IA-2 is cleaved and moves to the nucleus where it enhances transcription of the insulin gene []. The mature ectodomain of IA-2 participates in adhesion to the extracellular matrix and is self-proteolysed in vitro by reactive oxygen species, which may be anew shedding mechanism []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
26
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Primo ME |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2. |
Volume: |
283 |
Issue: |
8 |
Pages: |
4674-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trajkovski M |
Year: |
2004 |
Journal: |
J Cell Biol |
Title: |
Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cells. |
Volume: |
167 |
Issue: |
6 |
Pages: |
1063-74 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
IA-2 (also known as PTPRN or ICA512) and phogrin (also known as PTPRN2, IA-2b, IAR or ICAAR) are homologous protein-tyrosine phosphatase (PTP) receptors. They have a signal peptide, an ectodomain, a single-pass transmembrane region, and a single intracellular PTP domain. Processing of pro IA-2 by furin-like hormone convertases produces mature IA-2, which lacks the signal peptide and an adjacent fragment (residues 1-448). Upon exocytosis, the cytoplasmic domain of IA-2 is cleaved and moves to the nucleus where it enhances transcription of the insulin gene []. The mature ectodomain of IA-2 participates in adhesion to the extracellular matrix and is self-proteolysed in vitro by reactive oxygen species, which may be a new shedding mechanism []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
934
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
832
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
979
|
Fragment?: |
false |
|
•
•
•
•
•
|