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Search results 201 to 230 out of 230 for Vps33a

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0.017s

Type

Details

Score

Publication

25783203 | -

First Author:	Wartosch L
Year:	2015
Journal:	Traffic
Title:	Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes.
Volume:	16
Issue:	7
Pages:	727-42

•

Publication

23901104 | -

First Author:	Graham SC
Year:	2013
Journal:	Proc Natl Acad Sci U S A
Title:	Structural basis of Vps33A recruitment to the human HOPS complex by Vps16.
Volume:	110
Issue:	33
Pages:	13345-50

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Strain

MGI:2161263 | STOCK + Fgf5<go> Vps33a<bf>/+ Fgf5<go> Vps33a<bf>

Attribute String:

mutant stock

•

Strain

MGI:4840001 | B6;129P2-Vps33a<Gt(RRP092)Byg>/Mmucd

Attribute String:

mutant stock, gene trap

•

Allele

Vps33a<tm1e(EUCOMM)Hmgu> | MGI:5009612

Name:	VPS33A CORVET/HOPS core subunit; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type:	Targeted
Attribute String:	Null/knockout, Reporter

•

Strain

MGI:5649932 | (STOCK Hm Pgm2<b> Vps33a<bf> Gusb<b> Mdh2<a> x STOCK + Pgm2<a> + Gusb<a> Mdh2<b>)F1

Attribute String:

mutant stock, F1 hybrid

•

Allele

Vps33a<em2(IMPC)Tcp> | MGI:6157271

Name:	VPS33A CORVET/HOPS core subunit; endonuclease-mediated mutation 2, The Centre for Phenogenomics
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

•

Strain

MGI:2161348 | STOCK Rw Fgf5<go> Vps33a<bf>

Attribute String:

mutant stock

•

Strain

MGI:5656180 | involves: STOCK Rw Fgf5<go> Vps33a<bf>

Attribute String:

Not specified

•

Strain

MGI:5656181 | involves: 101/H * C3H/HeH * STOCK Rw Fgf5<go> Vps33a<bf>

Attribute String:

Not specified

•

Strain

MGI:3579317 | C3H101HF1 x STOCK Kit<W-sh> Fgf5<go> Vps33a<bf>/H

Attribute String:

spontaneous mutation, mutant stock, inversion, deletion

•

Strain

MGI:5650466 | (STOCK Rw Fgf5<go> Vps33a<bf>/+ Fgf5<go> Vps33a<bf> x M. spretus)F1

Attribute String:

mutant stock, F1 hybrid

•

Strain

MGI:2163576 | JGBF/LeTyJ

Attribute String:

inbred strain, spontaneous mutation

•

Strain

MGI:6866654 | C57BL/6NCrl-Vps33a<em2(IMPC)Tcp>/TcpMmucd

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Strain

MGI:6261468 | C57BL/6NCrl-Vps33a<em2(IMPC)Tcp>/Tcp

Attribute String:

coisogenic, targeted mutation

•

Genotype

Symbol:	Vps33a/Vps33a
Background:	C57BL/6NCrl-Vps33a/Tcp
Zygosity:	hm
Has Mutant Allele:	true

•

Strain

MGI:2163891 | JGBF/LeJ

Attribute String:

inbred strain, spontaneous mutation

•

Genotype

Symbol:	Vps33a/Vps33a<+>
Background:	C57BL/6NCrl-Vps33a/Tcp
Zygosity:	ht
Has Mutant Allele:	true

•

Protein Domain

IPR027121 | VPS33

Type:

Family

Description:

Vacuolar protein sorting-associated protein 33 (Vps33) is essential for vacuolar biogenesis, maturation and function. It is involved in the sorting of vacuolar proteins from the Golgi apparatus and their targeting to the vacuole []. In worm, fly, zebrafish and mammals two homologues of yeast Vps33p have been detected (termed VPS33A and VPS33B in humans). These homologues may reflect the evolution of organelle/tissue-specific functions in multicellular organisms. It is thought that VPS33B may be required for transport to conventional lysosomes, while VPS33A is mainly involved in biogenesis of melanosomes and related lysosomal compartments [, ].

•

Publication

12868054 | -

First Author:	Iwaki T
Year:	2003
Journal:	Yeast
Title:	Characterization of vps33+, a gene required for vacuolar biogenesis and protein sorting in Schizosaccharomyces pombe.
Volume:	20
Issue:	10
Pages:	845-55

•

Protein Domain

IPR043155 | VPS33_dom3b

Type:

Homologous_superfamily

Description:

Members of the Sec1 family include Sec1, Sly1, Slp1/Vps33, Vps45/Stt10 (yeast), Unc-18 (nematode), Munc-18b/muSec1, Munc-18c (mouse), Rop (Drosophila), Munc-18/n-Sec1/rbSec1A and rbSec1B (rat) [].The nSec1 polypeptide chain can be divided into three domains. The first domain, consists of a five-stranded parallel β-sheet flanked by five α-helices. The second domain, like the first one, has an α-β-alpha fold, however the β-sheet of domain 2 features five parallel strands with an additional antiparallel strand on one edge. The third domain is a large insertion between the third and fourth parallel strands of domain 2, and can be subdivided in two [].Vacuolar protein sorting-associated protein 33 (Vps33) is essential for vacuolar biogenesis, maturation and function. It is involved in the sorting of vacuolar proteins from the Golgi apparatus and their targeting to the vacuole []. In worm, fly, zebrafish and mammals two homologues of yeast Vps33p have been detected (termed VPS33A and VPS33B in humans). These homologues may reflect the evolution of organelle/tissue-specific functions in multicellular organisms. It is thought that VPS33B may be required for transport to conventional lysosomes, while VPS33A is mainly involved in biogenesis of melanosomes and related lysosomal compartments [, ].This superfamily entry represents the C-terminal region of domain 3 (called domain 3b) found in VPS33.

•

Publication

19109425 | J:159132

First Author:	Zhu GD
Year:	2009
Journal:	Mol Biol Cell
Title:	SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.
Volume:	20
Issue:	4
Pages:	1223-40

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Protein

Q9D2N9

Organism:	Mus musculus/domesticus
Length:	598
Fragment?:	false

•

Protein

Q80XK7

Organism:	Mus musculus/domesticus
Length:	598
Fragment?:	false

•

Protein

A0A0U1RPK8

Organism:	Mus musculus/domesticus
Length:	104
Fragment?:	true

•

Protein

S4R1H4

Organism:	Mus musculus/domesticus
Length:	143
Fragment?:	false

•

Protein

P59016

Organism:	Mus musculus/domesticus
Length:	617
Fragment?:	false

•

Protein

Q8C076

Organism:	Mus musculus/domesticus
Length:	617
Fragment?:	false

•

Publication

8769846 | J:31434

First Author:	Halachmi N
Year:	1996
Journal:	J Neurochem
Title:	The Sec1 family: a novel family of proteins involved in synaptic transmission and general secretion.
Volume:	66
Issue:	3
Pages:	889-97

•

Publication

10746715 | -

First Author:	Misura KM
Year:	2000
Journal:	Nature
Title:	Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex.
Volume:	404
Issue:	6776
Pages:	355-62

•

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