Type |
Details |
Score |
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
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Title: |
MGI Sequence Curation Reference |
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•
•
•
•
•
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Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
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Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
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Title: |
Nomenclature Committee Use |
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•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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•
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•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
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•
•
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•
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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•
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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•
•
•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Allele |
Name: |
transgene insertion, Mark Ginsberg |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence, Reporter |
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Strain |
Attribute String: |
mutant stock, transgenic |
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Publication |
First Author: |
Mahlknecht U |
Year: |
2009 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Fluorescence in situ hybridization and chromosomal organization of the sirtuin 4 gene (Sirt4) in the mouse. |
Volume: |
382 |
Issue: |
4 |
Pages: |
685-90 |
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•
•
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Publication |
First Author: |
Blagoev B |
Year: |
2002 |
Journal: |
Gene |
Title: |
Cloning of rat thymic stromal lymphopoietin receptor (TSLPR) and characterization of genomic structure of murine Tslpr gene. |
Volume: |
284 |
Issue: |
1-2 |
Pages: |
161-8 |
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•
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Publication |
First Author: |
McCarthy EA |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
A mutation inactivating the mitochondrial inner membrane folate transporter creates a glycine requirement for survival of chinese hamster cells. |
Volume: |
279 |
Issue: |
32 |
Pages: |
33829-36 |
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•
•
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•
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Publication |
First Author: |
Kim J |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Formate rescues neural tube defects caused by mutations in Slc25a32. |
Volume: |
115 |
Issue: |
18 |
Pages: |
4690-4695 |
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•
•
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•
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Publication |
First Author: |
Spaan AN |
Year: |
2005 |
Journal: |
Mol Genet Metab |
Title: |
Identification of the human mitochondrial FAD transporter and its potential role in multiple acyl-CoA dehydrogenase deficiency. |
Volume: |
86 |
Issue: |
4 |
Pages: |
441-7 |
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•
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•
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Publication |
First Author: |
Palmieri F |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Molecular identification and functional characterization of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins. |
Volume: |
284 |
Issue: |
45 |
Pages: |
31249-59 |
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•
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Publication |
First Author: |
Fernie AR |
Year: |
2020 |
Journal: |
Biomolecules |
Title: |
Metabolic Roles of Plant Mitochondrial Carriers. |
Volume: |
10 |
Issue: |
7 |
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•
•
•
•
•
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Publication |
First Author: |
Bedhomme M |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Folate metabolism in plants: an Arabidopsis homolog of the mammalian mitochondrial folate transporter mediates folate import into chloroplasts. |
Volume: |
280 |
Issue: |
41 |
Pages: |
34823-31 |
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•
•
•
•
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Publication |
First Author: |
Luongo TS |
Year: |
2020 |
Journal: |
Nature |
Title: |
SLC25A51 is a mammalian mitochondrial NAD+ transporter. |
Volume: |
588 |
Issue: |
7836 |
Pages: |
174-179 |
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•
•
•
•
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Publication |
First Author: |
Todisco S |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Identification of the mitochondrial NAD+ transporter in Saccharomyces cerevisiae. |
Volume: |
281 |
Issue: |
3 |
Pages: |
1524-31 |
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•
•
•
•
•
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Publication |
First Author: |
Bafunno V |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Riboflavin uptake and FAD synthesis in Saccharomyces cerevisiae mitochondria: involvement of the Flx1p carrier in FAD export. |
Volume: |
279 |
Issue: |
1 |
Pages: |
95-102 |
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Publication |
First Author: |
Tzagoloff A |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
FLX1 codes for a carrier protein involved in maintaining a proper balance of flavin nucleotides in yeast mitochondria. |
Volume: |
271 |
Issue: |
13 |
Pages: |
7392-7 |
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Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of substrate carrier proteins that are related to the nicotinamide adenine dinucleotide transporter found in mitochondria, including human NAD/FAD transporter SLC25A32, yeast Yea6/Flx1/Yia6, and AtNDT1/AtNDT2/PXN/AtFOLT1 from Arabidopsis. Structurally, they consist of three tandem repeats of a domain of approximately one hundred residues. Each of these domains contains two transmembrane regions.In budding yeasts, Yea6 and Yia6 are mitochondrial inner membrane carrier protein that mediates the import of NAD+ into mitochondria [, ]. Flx1 transports FAD from the cytosol to the mitochondrial matrix [, ].In humans, SLC25A32 transports folate and FAD across the inner membranes of mitochondria [, , ]. Mutations in the SLC25A32 gene cause neural tube defects (NTD) []. SLC25A32 has also been implicated in multiple acyl-CoA dehydrogenase deficiency (MADD) or glutaric aciduria type II (GAII) []. In Arabidopsis, AtNDT1 and AtNDT2 are able to catalyze the import of NAD+ in mitochondria []. PXN (At2g39970) is a peroxisomal NAD carrier that is able to catalyze NAD, NADH, AMP, ADP, adenosine 3', 5'-phosphate (PAP) and CoA transport. It supplies the peroxisomes with NAD by importing this coenzyme from the cytosol in exchange with AMP []. AtFOLT1 (At5g66380) has been shown to mediate folate import into chloroplast []. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
316
|
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
316
|
Fragment?: |
false |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
123
|
Fragment?: |
false |
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•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
316
|
Fragment?: |
false |
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•
•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
269
|
Fragment?: |
true |
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•
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Publication |
First Author: |
The Jackson Laboratory |
Year: |
2005 |
Journal: |
Unpublished |
Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
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