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Search results 1 to 100 out of 127 for Ffar1

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
2864 | FFAR1
Type: gene
Organism: human
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Gene
618180 | FFAR1
Type: gene
Organism: cattle
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Gene
708620 | FFAR1
Type: gene
Organism: macaque, rhesus
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Gene
266607 | Ffar1
Type: gene
Organism: rat
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Gene
612661 | FFAR1
Type: gene
Organism: dog, domestic
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Gene
468836 | FFAR1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2684079 | Ffar1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
29031729 | J:251773
First Author: Sabrautzki S
Year: 2017
Journal: Mol Metab
Title: Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance.
Volume: 6
Issue: 10
Pages: 1304-1312
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Publication
16054069 | J:129843
First Author: Steneberg P
Year: 2005
Journal: Cell Metab
Title: The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse.
Volume: 1
Issue: 4
Pages: 245-58
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Publication
24130766 | J:215962
First Author: Yabuki C
Year: 2013
Journal: PLoS One
Title: A novel antidiabetic drug, fasiglifam/TAK-875, acts as an ago-allosteric modulator of FFAR1.
Volume: 8
Issue: 10
Pages: e76280
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Publication
18678612 | J:141957
First Author: Lan H
Year: 2008
Journal: Diabetes
Title: Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease.
Volume: 57
Issue: 11
Pages: 2999-3006
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Publication
38036170 | J:344322
 
First Author: Dragano NRV
Year: 2024
Journal: Mol Metab
Title: Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance.
Volume: 79
Pages: 101840
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Publication
26408932 | J:231391
First Author: Kristinsson H
Year: 2015
Journal: Biochim Biophys Acta
Title: Free fatty acid receptor 1 (FFAR1/GPR40) signaling affects insulin secretion by enhancing mitochondrial respiration during palmitate exposure.
Volume: 1853
Issue: 12
Pages: 3248-57
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Publication
31525244 | J:279964
First Author: Ueno H
Year: 2019
Journal: PLoS One
Title: GPR40 full agonism exerts feeding suppression and weight loss through afferent vagal nerve.
Volume: 14
Issue: 9
Pages: e0222653
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Publication
29330456 | J:260097
First Author: Tunaru S
Year: 2018
Journal: Nat Commun
Title: 20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1.
Volume: 9
Issue: 1
Pages: 177
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Publication
33543237 | J:301540
 
First Author: Croze ML
Year: 2021
Journal: Endocrinology
Title: Combined Deletion of Free Fatty-Acid Receptors 1 and 4 Minimally Impacts Glucose Homeostasis in Mice.
Volume: 162
Issue: 3
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Publication
29796668 | J:263914
First Author: Li J
Year: 2018
Journal: Endocrinology
Title: FFAR4 Is Involved in Regulation of Neurotensin Release From Neuroendocrine Cells and Male C57BL/6 Mice.
Volume: 159
Issue: 8
Pages: 2939-2952
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Publication
30333365 | J:295664
First Author: Kohara K
Year: 2019
Journal: Endocr J
Title: Suppression of free fatty acid receptor 1 expression in pancreatic β-cells in obese type 2 diabetic db/db mice: a potential role of pancreatic and duodenal homeobox factor 1.
Volume: 66
Issue: 1
Pages: 43-50
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Publication
26974308 | J:234821
First Author: Joyal JS
Year: 2016
Journal: Nat Med
Title: Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1.
Volume: 22
Issue: 4
Pages: 439-45
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Protein Coding Gene
MGP_CAROLIEiJ_G0029548 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032048 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032025 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031958 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032032 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031751 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2684079 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032498 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031085 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031717 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031869 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031826 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031950 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031862 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032526 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030809 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031195 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012782 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030644 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12496284 | J:85392
First Author: Briscoe CP
Year: 2003
Journal: J Biol Chem
Title: The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids.
Volume: 278
Issue: 13
Pages: 11303-11
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Publication
17395749 | J:122092
First Author: Latour MG
Year: 2007
Journal: Diabetes
Title: GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo.
Volume: 56
Issue: 4
Pages: 1087-94
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Publication
18559658 | J:141776
First Author: Kebede M
Year: 2008
Journal: Diabetes
Title: The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.
Volume: 57
Issue: 9
Pages: 2432-7
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Publication
23335512 | J:196896
First Author: Wauquier F
Year: 2013
Journal: J Biol Chem
Title: The free fatty acid receptor G protein-coupled receptor 40 (GPR40) protects from bone loss through inhibition of osteoclast differentiation.
Volume: 288
Issue: 9
Pages: 6542-51
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Publication
20955703 | J:248598
First Author: Liou AP
Year: 2011
Journal: Gastroenterology
Title: The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin.
Volume: 140
Issue: 3
Pages: 903-12
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Publication
29053717 | J:248129
First Author: Pachanski MJ
Year: 2017
Journal: PLoS One
Title: GPR40 partial agonists and AgoPAMs: Differentiating effects on glucose and hormonal secretions in the rodent.
Volume: 12
Issue: 10
Pages: e0186033
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Publication
23331570 | J:275372
First Author: Matsuda-Nagasumi K
Year: 2013
Journal: Diabetes Obes Metab
Title: Lack of GPR40/FFAR1 does not induce diabetes even under insulin resistance condition.
Volume: 15
Issue: 6
Pages: 538-45
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Publication
23520164 | J:218877
First Author: Honoré JC
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Fatty acid receptor Gpr40 mediates neuromicrovascular degeneration induced by transarachidonic acids in rodents.
Volume: 33
Issue: 5
Pages: 954-61
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Publication
19720802 | J:154377
First Author: Alquier T
Year: 2009
Journal: Diabetes
Title: Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets.
Volume: 58
Issue: 11
Pages: 2607-15
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Publication
28723961 | J:246124
First Author: Nakamoto K
Year: 2017
Journal: PLoS One
Title: Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice.
Volume: 12
Issue: 7
Pages: e0180610
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Publication
29414687 | J:259191
First Author: Syed I
Year: 2018
Journal: Cell Metab
Title: Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.
Volume: 27
Issue: 2
Pages: 419-427.e4
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Publication
28769007 | J:273946
First Author: Aizawa F
Year: 2017
Journal: Biol Pharm Bull
Title: The Deletion of GPR40/FFAR1 Signaling Damages Maternal Care and Emotional Function in Female Mice.
Volume: 40
Issue: 8
Pages: 1255-1259
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Publication
27979701 | J:274191
First Author: Aizawa F
Year: 2016
Journal: J Pharmacol Sci
Title: GPR40/FFAR1 deficient mice increase noradrenaline levels in the brain and exhibit abnormal behavior.
Volume: 132
Issue: 4
Pages: 249-254
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Publication
36331958 | J:331048
First Author: Lu Z
Year: 2022
Journal: PLoS One
Title: Loss of GPR40 in LDL receptor-deficient mice exacerbates high-fat diet-induced hyperlipidemia and nonalcoholic steatohepatitis.
Volume: 17
Issue: 11
Pages: e0277251
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877911
Specimen Label: UC Davis_1877911
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877912
Specimen Label: UC Davis_1877912
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877903
Specimen Label: UC Davis_1877903
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877904
Specimen Label: UC Davis_1877904
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1866628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877900
Specimen Label: UC Davis_1877900
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877913
Specimen Label: UC Davis_1877913
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877914
Specimen Label: UC Davis_1877914
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877905
Specimen Label: UC Davis_1877905
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877906
Specimen Label: UC Davis_1877906
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877907
Specimen Label: UC Davis_1877907
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877909
Specimen Label: UC Davis_1877909
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877895
Specimen Label: UC Davis_1877895
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1885228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877899
Specimen Label: UC Davis_1877899
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877897
Specimen Label: UC Davis_1877897
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877898
Specimen Label: UC Davis_1877898
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877908
Specimen Label: UC Davis_1877908
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877910
Specimen Label: UC Davis_1877910
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877901
Specimen Label: UC Davis_1877901
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692808
Age: postnatal adult
Image: UC Davis_1877902
Specimen Label: UC Davis_1877902
Detected: true
Specimen Num: 12
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Publication
20573884 | J:161517
First Author: Cartoni C
Year: 2010
Journal: J Neurosci
Title: Taste preference for fatty acids is mediated by GPR40 and GPR120.
Volume: 30
Issue: 25
Pages: 8376-82
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Publication
24742677 | J:214106
First Author: Suckow AT
Year: 2014
Journal: J Biol Chem
Title: Alteration of the glucagon axis in GPR120 (FFAR4) knockout mice: a role for GPR120 in glucagon secretion.
Volume: 289
Issue: 22
Pages: 15751-63
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Publication
24154510 | J:208098
First Author: Sclafani A
Year: 2013
Journal: Am J Physiol Regul Integr Comp Physiol
Title: GPR40 and GPR120 fatty acid sensors are critical for postoral but not oral mediation of fat preferences in the mouse.
Volume: 305
Issue: 12
Pages: R1490-7
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Publication
23831422 | J:207048
 
First Author: Godinot N
Year: 2013
Journal: Neuroscience
Title: Activation of tongue-expressed GPR40 and GPR120 by non caloric agonists is not sufficient to drive preference in mice.
Volume: 250
Pages: 20-30
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Publication
28292762 | J:245567
First Author: Gorski JN
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: GPR40 reduces food intake and body weight through GLP-1.
Volume: 313
Issue: 1
Pages: E37-E47
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Publication
38361249 | J:345929
     
First Author: Koganesawa M
Year: 2024
Journal: Immunology
Title: Pla2g5 contributes to viral-like-induced lung inflammation through macrophage proliferation and LA/Ffar1 lung cell recruitment.
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Publication
25303528 | J:217547
First Author: Yore MM
Year: 2014
Journal: Cell
Title: Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.
Volume: 159
Issue: 2
Pages: 318-32
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Publication
29695780 | J:265430
First Author: Ho JD
Year: 2018
Journal: Nat Commun
Title: Structural basis for GPR40 allosteric agonism and incretin stimulation.
Volume: 9
Issue: 1
Pages: 1645
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Publication
29454750 | J:261104
First Author: Gagnon L
Year: 2018
Journal: Am J Pathol
Title: A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84.
Volume: 188
Issue: 5
Pages: 1132-1148
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Publication
29813102 | J:262387
First Author: Panse M
Year: 2018
Journal: PLoS One
Title: Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms.
Volume: 13
Issue: 5
Pages: e0198016
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Publication
35061031 | J:324761
First Author: Königs V
Year: 2022
Journal: Diabetes
Title: GPR40 Activation Abolishes Diabetes-Induced Painful Neuropathy by Suppressing VEGF-A Expression.
Volume: 71
Issue: 4
Pages: 774-787
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Publication
27779915 | J:240811
First Author: Ekberg JH
Year: 2016
Journal: Endocrinology
Title: GPR119, a Major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Coacting in Synergy With FFA1 (GPR40).
Volume: 157
Issue: 12
Pages: 4561-4569
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Publication
32632088 | J:294211
First Author: Engel DF
Year: 2020
Journal: Sci Rep
Title: Activation of GPR40 induces hypothalamic neurogenesis through p38- and BDNF-dependent mechanisms.
Volume: 10
Issue: 1
Pages: 11047
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Publication
33103454 | J:303069
First Author: Lu Z
Year: 2021
Journal: Am J Physiol Endocrinol Metab
Title: GPR40 deficiency is associated with hepatic FAT/CD36 upregulation, steatosis, inflammation, and cell injury in C57BL/6 mice.
Volume: 320
Issue: 1
Pages: E30-E42
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Publication
23403053 | J:200805
First Author: Xiong Y
Year: 2013
Journal: Mol Cell Endocrinol
Title: Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1.
Volume: 369
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