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Search results 101 to 200 out of 1123 for Aim2

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Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Schattgen SA
Year: 2016
Journal: J Immunol
Title: Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2.
Volume: 196
Issue: 1
Pages: 29-33
Publication
First Author: Xiao J
Year: 2020
Journal: PLoS Biol
Title: Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.
Volume: 18
Issue: 8
Pages: e3000807
Publication
First Author: Panchanathan R
Year: 2012
Journal: J Immunol
Title: Distinct regulation of murine lupus susceptibility genes by the IRF5/Blimp-1 axis.
Volume: 188
Issue: 1
Pages: 270-8
Publication
First Author: Ulland TK
Year: 2013
Journal: Infect Immun
Title: Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation.
Volume: 81
Issue: 1
Pages: 201-8
Publication
First Author: Periasamy S
Year: 2016
Journal: PLoS Pathog
Title: Inflammasome-Independent NLRP3 Restriction of a Protective Early Neutrophil Response to Pulmonary Tularemia.
Volume: 12
Issue: 12
Pages: e1006059
Publication
First Author: Tsuchiya K
Year: 2010
Journal: J Immunol
Title: Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes.
Volume: 185
Issue: 2
Pages: 1186-95
Publication
First Author: Gomes MT
Year: 2013
Journal: J Immunol
Title: Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.
Volume: 190
Issue: 7
Pages: 3629-38
Publication
First Author: Ge J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking.
Volume: 109
Issue: 16
Pages: 6193-8
Publication  
First Author: Cridland JA
Year: 2012
Journal: BMC Evol Biol
Title: The mammalian PYHIN gene family: phylogeny, evolution and expression.
Volume: 12
Pages: 140
Publication
First Author: Gray EE
Year: 2016
Journal: Immunity
Title: The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.
Volume: 45
Issue: 2
Pages: 255-66
Publication
First Author: Costa Franco MM
Year: 2018
Journal: J Immunol
Title: Brucella abortus Triggers a cGAS-Independent STING Pathway To Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation.
Volume: 200
Issue: 2
Pages: 607-622
Publication
First Author: Greaney AJ
Year: 2020
Journal: J Leukoc Biol
Title: Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1β release is a neutrophil and PAD4-dependent event.
Volume: 108
Issue: 3
Pages: 773-786
Publication  
First Author: Robinson KM
Year: 2018
Journal: JCI Insight
Title: The inflammasome potentiates influenza/Staphylococcus aureus superinfection in mice.
Volume: 3
Issue: 7
Publication
First Author: Kailasan Vanaja S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome.
Volume: 111
Issue: 21
Pages: 7765-70
Publication
First Author: Sivaraman V
Year: 2015
Journal: PLoS Pathog
Title: Yersinia pestis activates both IL-1β and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague.
Volume: 11
Issue: 3
Pages: e1004688
Publication
First Author: Wang Y
Year: 2017
Journal: Immunity
Title: Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection.
Volume: 46
Issue: 3
Pages: 393-404
Publication
First Author: Yan S
Year: 2018
Journal: J Immunol
Title: Deficiency of the AIM2-ASC Signal Uncovers the STING-Driven Overreactive Response of Type I IFN and Reciprocal Depression of Protective IFN-γ Immunity in Mycobacterial Infection.
Volume: 200
Issue: 3
Pages: 1016-1026
Publication
First Author: Kader M
Year: 2017
Journal: PLoS Pathog
Title: MyD88-dependent inflammasome activation and autophagy inhibition contributes to Ehrlichia-induced liver injury and toxic shock.
Volume: 13
Issue: 10
Pages: e1006644
GO Term
Publication
First Author: Shimada K
Year: 2012
Journal: Immunity
Title: Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Volume: 36
Issue: 3
Pages: 401-14
Publication
First Author: Creasey EA
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The protein SdhA maintains the integrity of the Legionella-containing vacuole.
Volume: 109
Issue: 9
Pages: 3481-6
Publication
First Author: Nakahira K
Year: 2011
Journal: Nat Immunol
Title: Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
Volume: 12
Issue: 3
Pages: 222-30
Publication  
First Author: Sanman LE
Year: 2016
Journal: Elife
Title: Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death.
Volume: 5
Pages: e13663
Publication
First Author: Park YH
Year: 2016
Journal: Nat Immunol
Title: Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS.
Volume: 17
Issue: 8
Pages: 914-21
Publication
First Author: Liu Z
Year: 2012
Journal: J Biol Chem
Title: Role of inflammasomes in host defense against Citrobacter rodentium infection.
Volume: 287
Issue: 20
Pages: 16955-64
Publication
First Author: Xu H
Year: 2014
Journal: Nature
Title: Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome.
Volume: 513
Issue: 7517
Pages: 237-41
Publication
First Author: Wooff Y
Year: 2020
Journal: Sci Rep
Title: Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration.
Volume: 10
Issue: 1
Pages: 2263
Publication
First Author: McNair NN
Year: 2018
Journal: Microbes Infect
Title: Inflammasome components caspase-1 and adaptor protein apoptosis-associated speck-like proteins are important in resistance to Cryptosporidium parvum.
Volume: 20
Issue: 6
Pages: 369-375
Publication
First Author: Lacey CA
Year: 2019
Journal: J Leukoc Biol
Title: IFN-γ-dependent nitric oxide suppresses Brucella-induced arthritis by inhibition of inflammasome activation.
Volume: 106
Issue: 1
Pages: 27-34
Publication
First Author: Briard B
Year: 2020
Journal: Nature
Title: Galactosaminogalactan activates the inflammasome to provide host protection.
Volume: 588
Issue: 7839
Pages: 688-692
Publication
First Author: Yang D
Year: 2015
Journal: Immunity
Title: Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock.
Volume: 43
Issue: 5
Pages: 923-32
Publication
First Author: Duffy EB
Year: 2016
Journal: J Leukoc Biol
Title: FcγR mediates TLR2- and Syk-dependent NLRP3 inflammasome activation by inactivated Francisella tularensis LVS immune complexes.
Volume: 100
Issue: 6
Pages: 1335-1347
Publication  
First Author: Yao Y
Year: 2017
Journal: Nat Commun
Title: Antigen-specific CD8+ T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin.
Volume: 8
Pages: 15402
Publication
First Author: Kuriakose T
Year: 2018
Journal: J Immunol
Title: IRF1 Is a Transcriptional Regulator of ZBP1 Promoting NLRP3 Inflammasome Activation and Cell Death during Influenza Virus Infection.
Volume: 200
Issue: 4
Pages: 1489-1495
Publication
First Author: Samir P
Year: 2019
Journal: Nature
Title: DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome.
Volume: 573
Issue: 7775
Pages: 590-594
Publication
First Author: Qi X
Year: 2016
Journal: J Exp Med
Title: Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection.
Volume: 213
Issue: 10
Pages: 2081-97
Publication
First Author: Place DE
Year: 2018
Journal: Am J Pathol
Title: ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming.
Volume: 188
Issue: 4
Pages: 1021-1030
Publication
First Author: Li Y
Year: 2018
Journal: Cell Death Differ
Title: Type I IFN operates pyroptosis and necroptosis during multidrug-resistant A. baumannii infection.
Volume: 25
Issue: 7
Pages: 1304-1318
Protein
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
Publication
First Author: Dasari TK
Year: 2020
Journal: J Biol Chem
Title: The nonreceptor tyrosine kinase SYK drives caspase-8/NLRP3 inflammasome-mediated autoinflammatory osteomyelitis.
Volume: 295
Issue: 11
Pages: 3394-3400
Publication
First Author: Feng S
Year: 2022
Journal: Nat Commun
Title: Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling.
Volume: 13
Issue: 1
Pages: 4395
Publication
First Author: Brunette RL
Year: 2012
Journal: J Exp Med
Title: Extensive evolutionary and functional diversity among mammalian AIM2-like receptors.
Volume: 209
Issue: 11
Pages: 1969-83
Publication
First Author: Rodriguez AE
Year: 2019
Journal: PLoS One
Title: Enhanced IL-1β production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae.
Volume: 14
Issue: 2
Pages: e0212236
Publication
First Author: Kayagaki N
Year: 2011
Journal: Nature
Title: Non-canonical inflammasome activation targets caspase-11.
Volume: 479
Issue: 7371
Pages: 117-21
Publication
First Author: Zhu S
Year: 2017
Journal: Nature
Title: Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.
Volume: 546
Issue: 7660
Pages: 667-670
Publication
First Author: Elinav E
Year: 2011
Journal: Cell
Title: NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis.
Volume: 145
Issue: 5
Pages: 745-57
Publication
First Author: Finethy R
Year: 2020
Journal: EMBO Rep
Title: Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.
Volume: 21
Issue: 11
Pages: e50830
Publication
First Author: Karki R
Year: 2021
Journal: Cell Rep
Title: ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis.
Volume: 37
Issue: 3
Pages: 109858
Publication
First Author: Dupaul-Chicoine J
Year: 2015
Journal: Immunity
Title: The Nlrp3 Inflammasome Suppresses Colorectal Cancer Metastatic Growth in the Liver by Promoting Natural Killer Cell Tumoricidal Activity.
Volume: 43
Issue: 4
Pages: 751-63
Publication
First Author: Kayagaki N
Year: 2013
Journal: Science
Title: Noncanonical inflammasome activation by intracellular LPS independent of TLR4.
Volume: 341
Issue: 6151
Pages: 1246-9
Publication
First Author: Swanson KV
Year: 2017
Journal: J Exp Med
Title: A noncanonical function of cGAMP in inflammasome priming and activation.
Volume: 214
Issue: 12
Pages: 3611-3626
Publication
First Author: Kitamoto S
Year: 2020
Journal: Cell
Title: The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis.
Volume: 182
Issue: 2
Pages: 447-462.e14
Publication
First Author: Zheng M
Year: 2020
Journal: J Biol Chem
Title: Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
Volume: 295
Issue: 41
Pages: 14040-14052
Publication
First Author: Zheng M
Year: 2020
Journal: Cell
Title: Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.
Volume: 181
Issue: 3
Pages: 674-687.e13
Publication
First Author: Vince JE
Year: 2018
Journal: Cell Rep
Title: The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.
Volume: 25
Issue: 9
Pages: 2339-2353.e4
Publication
First Author: Kim ML
Year: 2015
Journal: J Exp Med
Title: Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.
Volume: 212
Issue: 6
Pages: 927-38
Publication
First Author: Miyabe C
Year: 2019
Journal: J Clin Invest
Title: Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis.
Volume: 129
Issue: 9
Pages: 3610-3624
Publication
First Author: Mohammadi N
Year: 2016
Journal: PLoS One
Title: Neutrophils Directly Recognize Group B Streptococci and Contribute to Interleukin-1β Production during Infection.
Volume: 11
Issue: 8
Pages: e0160249
Publication
First Author: Briard B
Year: 2019
Journal: Nat Microbiol
Title: Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection.
Volume: 4
Issue: 2
Pages: 316-327
Publication  
First Author: Kuriakose T
Year: 2016
Journal: Sci Immunol
Title: ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.
Volume: 1
Issue: 2
Publication
First Author: Karki R
Year: 2018
Journal: Cell
Title: IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Volume: 173
Issue: 4
Pages: 920-933.e13
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
GO Term
GO Term
GO Term
UniProt Feature
Begin: 1
Description: Interferon-inducible protein AIM2
Type: chain
End: 354
GO Term
Pathway
Protein
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 94  
Fragment?: true
Publication
First Author: Rodrigue-Gervais IG
Year: 2018
Journal: Sci Rep
Title: The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes.
Volume: 8
Issue: 1
Pages: 8446