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Search results 1 to 100 out of 101 for Wrn

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Category: Publication
Type Details Score
Publication
First Author: Huang S
Year: 2000
Journal: Nucleic Acids Res
Title: Characterization of the human and mouse WRN 3'-->5' exonuclease.
Volume: 28
Issue: 12
Pages: 2396-405
Publication
First Author: Moser R
Year: 2012
Journal: Mol Cancer Res
Title: MYC-driven tumorigenesis is inhibited by WRN syndrome gene deficiency.
Volume: 10
Issue: 4
Pages: 535-45
Publication
First Author: Lombard DB
Year: 2000
Journal: Mol Cell Biol
Title: Mutations in the WRN gene in mice accelerate mortality in a p53-null background.
Volume: 20
Issue: 9
Pages: 3286-91
Publication
First Author: Kang SM
Year: 2021
Journal: Sci Rep
Title: Human WRN is an intrinsic inhibitor of progerin, abnormal splicing product of lamin A.
Volume: 11
Issue: 1
Pages: 9122
Publication
First Author: Aumailley L
Year: 2015
Journal: PLoS One
Title: Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice.
Volume: 10
Issue: 10
Pages: e0140292
Publication
First Author: Xue Y
Year: 2002
Journal: Biochemistry
Title: A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3'- 5' exonuclease and 5'-protruding strand endonuclease activities.
Volume: 41
Issue: 9
Pages: 2901-12
Publication
First Author: Aumailley L
Year: 2018
Journal: FASEB J
Title: Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein.
Volume: 32
Issue: 7
Pages: 3623-3640
Publication
First Author: Massip L
Year: 2006
Journal: Exp Gerontol
Title: Increased insulin, triglycerides, reactive oxygen species, and cardiac fibrosis in mice with a mutation in the helicase domain of the Werner syndrome gene homologue.
Volume: 41
Issue: 2
Pages: 157-68
Publication
First Author: Laud PR
Year: 2005
Journal: Genes Dev
Title: Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway.
Volume: 19
Issue: 21
Pages: 2560-70
Publication
First Author: Shen JC
Year: 2000
Journal: Trends Genet
Title: The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases.
Volume: 16
Issue: 5
Pages: 213-20
Publication
First Author: Chang S
Year: 2005
Journal: Int J Biochem Cell Biol
Title: A mouse model of Werner Syndrome: what can it tell us about aging and cancer?
Volume: 37
Issue: 5
Pages: 991-9
Publication
First Author: Kahyo T
Year: 2008
Journal: FEBS Lett
Title: Sirtuin-mediated deacetylation pathway stabilizes Werner syndrome protein.
Volume: 582
Issue: 17
Pages: 2479-83
Publication
First Author: Aumailley L
Year: 2018
Journal: PLoS One
Title: Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional Werner syndrome (Wrn) mutant protein.
Volume: 13
Issue: 3
Pages: e0193170
Publication  
First Author: Aumailley L
Year: 2015
Journal: Exp Gerontol
Title: Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase.
Volume: 72
Pages: 192-203
Publication
First Author: Chang S
Year: 2004
Journal: Nat Genet
Title: Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
Volume: 36
Issue: 8
Pages: 877-82
Publication
First Author: Wu J
Year: 1998
Journal: Mech Ageing Dev
Title: Effect of age and apoptosis on the mouse homologue of the huWRN gene.
Volume: 103
Issue: 1
Pages: 27-44
Publication
First Author: Kawabe Yi
Year: 2001
Journal: J Biol Chem
Title: A novel protein interacts with the Werner's syndrome gene product physically and functionally.
Volume: 276
Issue: 23
Pages: 20364-9
Publication
First Author: Kawabe Y
Year: 2000
Journal: J Biol Chem
Title: Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1.
Volume: 275
Issue: 28
Pages: 20963-6
Publication
First Author: Kanagaraj R
Year: 2012
Journal: Nucleic Acids Res
Title: Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage.
Volume: 40
Issue: 17
Pages: 8449-59
Publication
First Author: Bachrati CZ
Year: 2003
Journal: Biochem J
Title: RecQ helicases: suppressors of tumorigenesis and premature aging.
Volume: 374
Issue: Pt 3
Pages: 577-606
Publication
First Author: Du X
Year: 2004
Journal: Mol Cell Biol
Title: Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes.
Volume: 24
Issue: 19
Pages: 8437-46
Publication
First Author: Lebel M
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity.
Volume: 95
Issue: 22
Pages: 13097-102
Publication
First Author: Pignolo RJ
Year: 2008
Journal: Aging Cell
Title: Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis.
Volume: 7
Issue: 1
Pages: 23-31
Publication
First Author: Deschênes F
Year: 2005
Journal: Hum Mol Genet
Title: In vivo misregulation of genes involved in apoptosis, development and oxidative stress in mice lacking both functional Werner syndrome protein and poly(ADP-ribose) polymerase-1.
Volume: 14
Issue: 21
Pages: 3293-308
Publication
First Author: Lebel M
Year: 2003
Journal: Am J Pathol
Title: Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice.
Volume: 162
Issue: 5
Pages: 1559-69
Publication
First Author: Leder A
Year: 2002
Journal: Oncogene
Title: Genetic interaction between the unstable v-Ha-RAS transgene (Tg.AC) and the murine Werner syndrome gene: transgene instability and tumorigenesis.
Volume: 21
Issue: 43
Pages: 6657-68
Publication
First Author: Suzuki T
Year: 2001
Journal: Oncogene
Title: Diverged nuclear localization of Werner helicase in human and mouse cells.
Volume: 20
Issue: 20
Pages: 2551-8
Publication
First Author: Cheng WH
Year: 2003
Journal: Mol Cell Biol
Title: Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution.
Volume: 23
Issue: 18
Pages: 6385-95
Publication
First Author: Lebel M
Year: 2002
Journal: Carcinogenesis
Title: Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue.
Volume: 23
Issue: 1
Pages: 213-6
Publication
First Author: Lebel M
Year: 2001
Journal: Cancer Res
Title: Tumorigenic effect of nonfunctional p53 or p21 in mice mutant in the Werner syndrome helicase.
Volume: 61
Issue: 5
Pages: 1816-9
Publication
First Author: Imamura O
Year: 1997
Journal: Genomics
Title: Cloning of a mouse homologue of the human Werner syndrome gene and assignment to 8A4 by fluorescence in situ hybridization.
Volume: 41
Issue: 2
Pages: 298-300
Publication  
First Author: Rekik K
Year: 2017
Journal: Behav Brain Res
Title: Cognitive deficit in hippocampal-dependent tasks in Werner syndrome mouse model.
Volume: 323
Pages: 68-77
Publication
First Author: Brennan TA
Year: 2014
Journal: Dis Model Mech
Title: Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis.
Volume: 7
Issue: 5
Pages: 583-92
Publication
First Author: Oshima J
Year: 2000
Journal: In Vivo
Title: Comparative aspects of the Werner syndrome gene.
Volume: 14
Issue: 1
Pages: 165-72
Publication
First Author: Yu CE
Year: 1996
Journal: Science
Title: Positional cloning of the Werner's syndrome gene.
Volume: 272
Issue: 5259
Pages: 258-62
Publication
First Author: Wang H
Year: 2013
Journal: J Mol Med (Berl)
Title: R-Spondin 1 promotes vibration-induced bone formation in mouse models of osteoporosis.
Volume: 91
Issue: 12
Pages: 1421-9
Publication
First Author: Chung L
Year: 2015
Journal: Oncogene
Title: The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers.
Volume: 34
Issue: 7
Pages: 902-11
Publication
First Author: Wang H
Year: 2012
Journal: Aging Cell
Title: Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging.
Volume: 11
Issue: 4
Pages: 704-13
Publication
First Author: Drosopoulos WC
Year: 2015
Journal: J Cell Biol
Title: BLM helicase facilitates telomere replication during leading strand synthesis of telomeres.
Volume: 210
Issue: 2
Pages: 191-208
Publication
First Author: Yu Q
Year: 2015
Journal: Cell Rep
Title: DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.
Volume: 11
Issue: 5
Pages: 785-797
Publication
First Author: Dron M
Year: 2000
Journal: Genomics
Title: Mouse scrapie responsive gene 1 (Scrg1): genomic organization, physical linkage to sap30, genetic mapping on chromosome 8, and expression in neuronal primary cell cultures.
Volume: 70
Issue: 1
Pages: 140-9
Publication
First Author: Sebastiani G
Year: 2006
Journal: Hum Mol Genet
Title: Mapping genetic modulators of amyloid plaque deposition in TgCRND8 transgenic mice.
Volume: 15
Issue: 15
Pages: 2313-23
Publication
First Author: McClive PJ
Year: 2003
Journal: Genesis
Title: Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad.
Volume: 37
Issue: 2
Pages: 84-90
Publication
First Author: Li Y
Year: 2015
Journal: Nature
Title: Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Volume: 521
Issue: 7553
Pages: 520-4
Publication      
First Author: Lo C
Year: 2011
Journal: MGI Direct Data Submission (B2B/CvDC)
Title: Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC)
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Wang L
Year: 2000
Journal: Genetics
Title: Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene.
Volume: 154
Issue: 1
Pages: 357-62
Publication
First Author: Si X
Year: 2018
Journal: Int J Biol Sci
Title: Loss of p21 promoted tumorigenesis in the background of telomere dysfunctions induced by TRF2 and Wrn deficiency.
Volume: 14
Issue: 2
Pages: 165-177
Publication
First Author: Liu H
Year: 2002
Journal: Nucleic Acids Res
Title: Distinct proteins encoded by alternative transcripts of the PURG gene, located contrapodal to WRN on chromosome 8, determined by differential termination/polyadenylation.
Volume: 30
Issue: 11
Pages: 2417-26
Publication
First Author: Yamamoto ML
Year: 2008
Journal: Mutat Res
Title: Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice.
Volume: 644
Issue: 1-2
Pages: 11-6
Publication
First Author: Gray MD
Year: 1997
Journal: Nat Genet
Title: The Werner syndrome protein is a DNA helicase.
Volume: 17
Issue: 1
Pages: 100-3
Publication
First Author: Yan H
Year: 1998
Journal: Nat Genet
Title: Replication focus-forming activity 1 and the Werner syndrome gene product.
Volume: 19
Issue: 4
Pages: 375-8
Publication
First Author: Suzuki N
Year: 1997
Journal: Nucleic Acids Res
Title: DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system.
Volume: 25
Issue: 15
Pages: 2973-8
Publication
First Author: Pezo V
Year: 2021
Journal: Science
Title: Noncanonical DNA polymerization by aminoadenine-based siphoviruses.
Volume: 372
Issue: 6541
Pages: 520-524
Publication
First Author: Andraos N
Year: 2004
Journal: J Biol Chem
Title: The highly processive DNA polymerase of bacteriophage T5. Role of the unique N and C termini.
Volume: 279
Issue: 48
Pages: 50609-18
Publication
First Author: Ichikawa K
Year: 2002
Journal: Nihon Yakurigaku Zasshi
Title: [Preparation of the gene targeted knockout mice for human premature aging diseases, Werner syndrome, and Rothmund-Thomson syndrome caused by the mutation of DNA helicases].
Volume: 119
Issue: 4
Pages: 219-26
Publication
First Author: Cheng WH
Year: 2007
Journal: Exp Gerontol
Title: Werner syndrome protein: functions in the response to DNA damage and replication stress in S-phase.
Volume: 42
Issue: 9
Pages: 871-8
Publication
First Author: Fang EF
Year: 2019
Journal: Nat Commun
Title: NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome.
Volume: 10
Issue: 1
Pages: 5284
Publication
First Author: Liu Z
Year: 1999
Journal: Structure
Title: The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins.
Volume: 7
Issue: 12
Pages: 1557-66
Publication
First Author: Armache KJ
Year: 2005
Journal: J Biol Chem
Title: Structures of complete RNA polymerase II and its subcomplex, Rpb4/7.
Volume: 280
Issue: 8
Pages: 7131-4
Publication
First Author: Morozov V
Year: 1997
Journal: Trends Biochem Sci
Title: A putative nucleic acid-binding domain in Bloom's and Werner's syndrome helicases.
Volume: 22
Issue: 11
Pages: 417-8
Publication
First Author: Ohhata T
Year: 2000
Journal: Gene
Title: Cloning, genomic structure and chromosomal localization of the gene encoding mouse DNA helicase RecQ helicase protein-like 4.
Volume: 261
Issue: 2
Pages: 251-8
Publication
First Author: Pereira M
Year: 2007
Journal: Mech Ageing Dev
Title: Interaction of human SUV3 RNA/DNA helicase with BLM helicase; loss of the SUV3 gene results in mouse embryonic lethality.
Volume: 128
Issue: 11-12
Pages: 609-17
Publication
First Author: Paul E
Year: 2009
Journal: Mamm Genome
Title: Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death.
Volume: 20
Issue: 2
Pages: 92-108
Publication  
First Author: Bopp A
Year: 2013
Journal: Cell Death Dis
Title: Rac1 modulates acute and subacute genotoxin-induced hepatic stress responses, fibrosis and liver aging.
Volume: 4
Pages: e558
Publication
First Author: Morales C
Year: 2020
Journal: J Biol Chem
Title: PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.
Volume: 295
Issue: 1
Pages: 146-157
Publication
First Author: Zhao J
Year: 2019
Journal: Int J Biol Sci
Title: p53 Mutant p53N236S Induces Neural Tube Defects in Female Embryos.
Volume: 15
Issue: 9
Pages: 2006-2015
Publication
First Author: Croteau DL
Year: 2012
Journal: Aging Cell
Title: RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity.
Volume: 11
Issue: 3
Pages: 456-66
Publication
First Author: Newman JA
Year: 2015
Journal: Nucleic Acids Res
Title: Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes.
Volume: 43
Issue: 10
Pages: 5221-35