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Search results 1 to 100 out of 529 for Cpe

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Type Details Score
Gene
1363 | CPE
Type: gene
Organism: human
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Gene
422424 | CPE
Type: gene
Organism: chicken
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Gene
407979 | cpe
Type: gene
Organism: zebrafish
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Gene
708881 | CPE
Type: gene
Organism: macaque, rhesus
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Gene
100127580 | cpe
Type: gene
Organism: frog, western clawed
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Gene
280753 | CPE
Type: gene
Organism: cattle
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Gene
25669 | Cpe
Type: gene
Organism: rat
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Gene
475492 | CPE
Type: gene
Organism: dog, domestic
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Gene
461592 | CPE
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:101932 | Cpe
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
19767734 | J:154300
First Author: Plum L
Year: 2009
Journal: Nat Med
Title: The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake.
Volume: 15
Issue: 10
Pages: 1195-201
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Publication
16417576 | J:105999
First Author: Lim J
Year: 2006
Journal: J Neurochem
Title: Altered neuropeptide processing in prefrontal cortex of Cpe (fat/fat) mice: implications for neuropeptide discovery.
Volume: 96
Issue: 4
Pages: 1169-81
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Publication
30503215 | J:283096
 
First Author: Rollins CPE
Year: 2019
Journal: Neuroimage Clin
Title: Contributions of a high-fat diet to Alzheimer's disease-related decline: A longitudinal behavioural and structural neuroimaging study in mouse models.
Volume: 21
Pages: 101606
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Publication
35618016 | J:324730
 
First Author: Fricker LD
Year: 2022
Journal: Brain Res
Title: Mice heterozygous for a null mutation of CPE show reduced expression of carboxypeptidase e mRNA and enzyme activity but normal physiology, behavior, and levels of neuropeptides.
Volume: 1789
Pages: 147951
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Publication
- | J:148983
     
First Author: Leiter EH
Year: 2009
Journal: MGI Direct Data Submission
Title: Rescue of the Cpefat hyper pro-insulinemia phenotype by transgene expression of wild-type CPE
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Publication
10500303 | J:57979
First Author: Fricker LD
Year: 1999
Journal: Trends Biochem Sci
Title: Peptides, enzymes and obesity: new insights from a 'dead' enzyme.
Volume: 24
Issue: 10
Pages: 390-3
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Publication
7663508 | J:24436
First Author: Naggert JK
Year: 1995
Journal: Nat Genet
Title: Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity.
Volume: 10
Issue: 2
Pages: 135-42
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Publication
17177860 | J:116679
First Author: Singh U
Year: 2006
Journal: Differentiation
Title: Carboxypeptidase E in the mouse placenta.
Volume: 74
Issue: 9-10
Pages: 648-60
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Author
Rollins CPE
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Publication
11375130 | J:88426
First Author: Friis-Hansen L
Year: 2001
Journal: J Endocrinol
Title: Attenuated processing of proglucagon and glucagon-like peptide-1 in carboxypeptidase E-deficient mice.
Volume: 169
Issue: 3
Pages: 595-602
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Publication
33217339 | J:324731
First Author: Fricker LD
Year: 2021
Journal: Cell Chem Biol
Title: Neuropeptidomic Analysis of a Genetically Defined Cell Type in Mouse Brain and Pituitary.
Volume: 28
Issue: 1
Pages: 105-112.e4
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Publication
9893169 | J:52393
First Author: Gomez P
Year: 1999
Journal: Proc Soc Exp Biol Med
Title: Carboxypeptidase E (CPE) deficiency in mice with the fat mutation have reduced stomach function.
Volume: 220
Issue: 1
Pages: 52-3
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Publication
10221600 | J:53742
First Author: Wang W
Year: 1998
Journal: Endocrine
Title: Adult carboxypeptidase E-deficient fat/fat mice have a near-total depletion of brain CCK 8 accompanied by a massive accumulation of glycine and arginine extended CCK: identification of CCK 8 Gly as the immediate precursor of CCK 8 in rodent brain.
Volume: 9
Issue: 3
Pages: 329-32
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Publication
9019408 | J:38227
First Author: Cool DR
Year: 1997
Journal: Cell
Title: Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice.
Volume: 88
Issue: 1
Pages: 73-83
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Publication
12488357 | J:81410
First Author: Cawley NX
Year: 2003
Journal: Endocrinology
Title: Trafficking of mutant carboxypeptidase E to secretory granules in a beta-cell line derived from Cpe(fat)/Cpe(fat) mice.
Volume: 144
Issue: 1
Pages: 292-8
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Publication
15358678 | J:95741
First Author: Cawley NX
Year: 2004
Journal: Endocrinology
Title: The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits.
Volume: 145
Issue: 12
Pages: 5807-19
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Publication
19598241 | J:225036
First Author: Woronowicz A
Year: 2010
Journal: J Neurosci Res
Title: Carboxypeptidase E knockout mice exhibit abnormal dendritic arborization and spine morphology in central nervous system neurons.
Volume: 88
Issue: 1
Pages: 64-72
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Publication
20460579 | J:162932
First Author: Cawley NX
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: Obese carboxypeptidase E knockout mice exhibit multiple defects in peptide hormone processing contributing to low bone mineral density.
Volume: 299
Issue: 2
Pages: E189-97
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Publication
23977080 | J:206345
First Author: Cheng Y
Year: 2013
Journal: PLoS One
Title: Carboxypeptidase E/NFα1: a new neurotrophic factor against oxidative stress-induced apoptotic cell death mediated by ERK and PI3-K/AKT pathways.
Volume: 8
Issue: 8
Pages: e71578
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Publication
16219026 | J:103669
First Author: Zhu X
Year: 2005
Journal: J Neurochem
Title: Carboxypeptidase E is required for normal synaptic transmission from photoreceptors to the inner retina.
Volume: 95
Issue: 5
Pages: 1351-62
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Publication
20492353 | J:163488
First Author: Lou H
Year: 2010
Journal: J Neurochem
Title: Carboxypeptidase E cytoplasmic tail mediates localization of synaptic vesicles to the pre-active zone in hypothalamic pre-synaptic terminals.
Volume: 114
Issue: 3
Pages: 886-96
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Publication
15012590 | J:88683
First Author: Wei S
Year: 2004
Journal: J Endocrinol
Title: Obesity and diabetes in transgenic mice expressing proSAAS.
Volume: 180
Issue: 3
Pages: 357-68
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Publication
25051500 | J:219011
First Author: Bär F
Year: 2014
Journal: PLoS One
Title: Carboxypeptidase E modulates intestinal immune homeostasis and protects against experimental colitis in mice.
Volume: 9
Issue: 7
Pages: e102347
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Publication
19014391 | J:144752
First Author: Zhang X
Year: 2008
Journal: J Neurochem
Title: Peptidomics of Cpe(fat/fat) mouse brain regions: implications for neuropeptide processing.
Volume: 107
Issue: 6
Pages: 1596-613
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Publication
9771894 | J:50155
First Author: Lacourse KA
Year: 1998
Journal: FEBS Lett
Title: Altered processing of procholecystokinin in carboxypeptidase E-deficient fat mice: differential synthesis in neurons and endocrine cells.
Volume: 436
Issue: 1
Pages: 61-6
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Publication
9112393 | J:39758
First Author: Udupi V
Year: 1997
Journal: Endocrinology
Title: Effect of carboxypeptidase E deficiency on progastrin processing and gastrin messenger ribonucleic acid expression in mice with the fat mutation.
Volume: 138
Issue: 5
Pages: 1959-63
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Publication
9346885 | J:43715
First Author: Irminger JC
Year: 1997
Journal: J Biol Chem
Title: Proinsulin targeting to the regulated pathway is not impaired in carboxypeptidase E-deficient Cpefat/Cpefat mice.
Volume: 272
Issue: 44
Pages: 27532-4
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Publication
9348219 | J:43857
First Author: Varlamov O
Year: 1997
Journal: Endocrinology
Title: Beta-cell lines derived from transgenic Cpe(fat)/Cpe(fat) mice are defective in carboxypeptidase E and proinsulin processing.
Volume: 138
Issue: 11
Pages: 4883-92
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Publication
12438557 | J:88830
First Author: Boudarine M
Year: 2002
Journal: J Pharmacol Exp Ther
Title: Developmental changes in opioid peptides and their receptors in Cpe(fat)/Cpe(fat) mice lacking peptide processing enzyme carboxypeptidase E.
Volume: 303
Issue: 3
Pages: 1317-24
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Publication
37100779 | J:335208
First Author: Fan FC
Year: 2023
Journal: Transl Psychiatry
Title: Carboxypeptidase E conditional knockout mice exhibit learning and memory deficits and neurodegeneration.
Volume: 13
Issue: 1
Pages: 135
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Publication
18573344 | J:141757
First Author: Park JJ
Year: 2008
Journal: Mol Cell Neurosci
Title: A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons.
Volume: 39
Issue: 1
Pages: 63-73
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Publication
8940036 | J:36810
First Author: Fricker LD
Year: 1996
Journal: J Biol Chem
Title: Carboxypeptidase E activity is deficient in mice with the fat mutation. Effect on peptide processing.
Volume: 271
Issue: 48
Pages: 30619-24
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Publication
11038363 | J:66910
First Author: Berman Y
Year: 2001
Journal: J Biol Chem
Title: Impaired prohormone convertases in Cpe(fat)/Cpe(fat) mice.
Volume: 276
Issue: 2
Pages: 1466-73
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Publication
8770919 | J:34268
First Author: Rovere C
Year: 1996
Journal: Endocrinology
Title: Impaired processing of brain proneurotensin and promelanin-concentrating hormone in obese fat/fat mice.
Volume: 137
Issue: 7
Pages: 2954-8
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Publication
8662840 | J:33602
First Author: Varlamov O
Year: 1996
Journal: J Biol Chem
Title: Induced and spontaneous mutations at Ser202 of carboxypeptidase E. Effect on enzyme expression, activity, and intracellular routing.
Volume: 271
Issue: 24
Pages: 13981-6
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Publication
12270926 | J:80698
First Author: Nillni EA
Year: 2002
Journal: J Biol Chem
Title: Deficiencies in pro-thyrotropin-releasing hormone processing and abnormalities in thermoregulation in Cpefat/fat mice.
Volume: 277
Issue: 50
Pages: 48587-95
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Publication
9369230 | J:43612
First Author: Lacourse KA
Year: 1997
Journal: FEBS Lett
Title: Disturbed progastrin processing in carboxypeptidase E-deficient fat mice.
Volume: 416
Issue: 1
Pages: 45-50
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Publication
9275097 | J:42848
First Author: Cain BM
Year: 1997
Journal: Endocrinology
Title: Cholecystokinin (CCK) levels are greatly reduced in the brains but not the duodenums of Cpe(fat)/Cpe(fat) mice: a regional difference in the involvement of carboxypeptidase E (Cpe) in pro-CCK processing.
Volume: 138
Issue: 9
Pages: 4034-7
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Publication
23825125 | J:202257
First Author: Murthy SR
Year: 2013
Journal: Endocrinology
Title: Carboxypeptidase E protects hippocampal neurons during stress in male mice by up-regulating prosurvival BCL2 protein expression.
Volume: 154
Issue: 9
Pages: 3284-93
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Publication
25426952 | J:225276
First Author: Qin XY
Year: 2014
Journal: PLoS One
Title: carboxypeptidase E-ΔN, a neuroprotein transiently expressed during development protects embryonic neurons against glutamate neurotoxicity.
Volume: 9
Issue: 11
Pages: e112996
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Publication
37364047 | J:339878
First Author: Chen YC
Year: 2023
Journal: Diabetes
Title: Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice.
Volume: 72
Issue: 9
Pages: 1277-1288
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Publication
24843127 | J:211360
First Author: Liew CW
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells.
Volume: 111
Issue: 22
Pages: E2319-28
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Publication
16219686 | J:102191
First Author: Hosaka M
Year: 2005
Journal: J Cell Sci
Title: Interaction between secretogranin III and carboxypeptidase E facilitates prohormone sorting within secretory granules.
Volume: 118
Issue: Pt 20
Pages: 4785-95
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Publication
31300553 | J:281152
First Author: Jo S
Year: 2019
Journal: J Biol Chem
Title: eIF4G1 and carboxypeptidase E axis dysregulation in O-GlcNAc transferase-deficient pancreatic β-cells contributes to hyperproinsulinemia in mice.
Volume: 294
Issue: 35
Pages: 13040-13050
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Publication
10393247 | J:56269
First Author: Chen A
Year: 1999
Journal: Gene
Title: NIMA-related kinases: isolation and characterization of murine nek3 and nek4 cDNAs, and chromosomal localization of nek1, nek2 and nek3.
Volume: 234
Issue: 1
Pages: 127-37
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Publication
12091495 | J:88773
First Author: Bouchard G
Year: 2002
Journal: J Lipid Res
Title: Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk.
Volume: 43
Issue: 7
Pages: 1105-13
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Protein Coding Gene
MGP_CAROLIEiJ_G0031084 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033642 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033549 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033620 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033330 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_101932 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034137 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032655 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033308 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033462 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033403 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033550 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033447 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034155 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032772 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021550 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032200 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16002559 | J:104048
First Author: Johnston RA
Year: 2006
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Augmented responses to ozone in obese carboxypeptidase E-deficient mice.
Volume: 290
Issue: 1
Pages: R126-33
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Publication
25009214 | J:240911
First Author: Dahm PH
Year: 2014
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Effect of antigen sensitization and challenge on oscillatory mechanics of the lung and pulmonary inflammation in obese carboxypeptidase E-deficient mice.
Volume: 307
Issue: 6
Pages: R621-33
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Publication
10631115 | J:60206
First Author: Friis-Hansen L
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Impaired feedback of gastric functions in carboxypeptidase E-deficient mice.
Volume: 267
Issue: 2
Pages: 638-42
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Publication
25203099 | J:223419
First Author: Mancuso P
Year: 2014
Journal: PLoS One
Title: No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice.
Volume: 9
Issue: 9
Pages: e106420
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Publication
7663503 | J:24138
First Author: Keightley PD
Year: 1995
Journal: Nat Genet
Title: Chewing the fat.
Volume: 10
Issue: 2
Pages: 125-6
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Publication
10657504 | J:60515
First Author: Shen FS
Year: 1999
Journal: Neuropeptides
Title: Altered biosynthesis and secretion of pro-opiomelanocortin in the intermediate and anterior pituitary of carboxypeptidase E-deficient, Cpe(fat)/ Cpe(fat)mice.
Volume: 33
Issue: 4
Pages: 276-80
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Publication
9144234 | J:40372
First Author: Shen FS
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Intracellular misrouting and abnormal secretion of adrenocorticotropin and growth hormone in cpefat mice associated with a carboxypeptidase E mutation.
Volume: 94
Issue: 10
Pages: 5314-9
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Publication
- | J:13651
 
First Author: Hummel KP
Year: 1974
Journal: Mouse News Lett
Title: fat = fat, Chr UN.
Volume: 50
Pages: 43
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Publication
11481435 | J:71090
First Author: Che FY
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Identification of peptides from brain and pituitary of Cpe(fat)/Cpe(fat) mice.
Volume: 98
Issue: 17
Pages: 9971-6
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Publication
10403572 | J:54845
First Author: Leiter EH
Year: 1999
Journal: Endocrine
Title: Physiologic and endocrinologic characterization of male sex-biased diabetes in C57BLKS/J mice congenic for the fat mutation at the carboxypeptidease E locus.
Volume: 10
Issue: 1
Pages: 57-66
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Publication
20299617 | J:185840
First Author: Johnston RA
Year: 2010
Journal: J Appl Physiol (1985)
Title: Onset of obesity in carboxypeptidase E-deficient mice and effect on airway responsiveness and pulmonary responses to ozone.
Volume: 108
Issue: 6
Pages: 1812-9
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Publication
9415050 | J:43795
First Author: Leiter EH
Year: 1997
Journal: J Endocrinol
Title: Carboxypeptidase E and obesity in the mouse.
Volume: 155
Issue: 2
Pages: 211-4
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Publication
30063439 | J:285908
First Author: Xiao L
Year: 2019
Journal: FASEB J
Title: Cloning, gene regulation, and neuronal proliferation functions of novel N-terminal-truncated carboxypeptidase E/neurotrophic factor-αl variants in embryonic mouse brain.
Volume: 33
Issue: 1
Pages: 808-820
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GXD Expression
GXD Expression
   
Probe: MGI:4947663
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4947691
Age: postnatal
Image: 2
Specimen Label: UE
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4947663
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:4947691
Age: embryonic day 1.0
Image: 2
Specimen Label: 2C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4947663
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:4947691
Age: embryonic day 2.0
Image: 2
Specimen Label: 4C
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:4947663
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:4947691
Age: embryonic day 3.0
Image: 2
Specimen Label: MO
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:4947663
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:4947691
Age: embryonic day 3.5
Image: 2
Specimen Label: BL
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:4947673
Assay Type: Western blot
Annotation Date: 2011-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4947696
Age: postnatal
Image: 2
Specimen Label: UE
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4947673
Assay Type: Western blot
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:4947696
Age: embryonic day 0.5
Image: 2
Specimen Label: 1C
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4947673
Assay Type: Western blot
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:4947696
Age: embryonic day 1.0
Image: 2
Specimen Label: 2C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4947673
Assay Type: Western blot
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:4947696
Age: embryonic day 3.5
Image: 2
Specimen Label: BL
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5910573
Assay Type: RT-PCR
Annotation Date: 2017-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160397
Stage: TS07
Assay Id: MGI:5910584
Age: embryonic day 5.5
Specimen Label: E5.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5910573
Assay Type: RT-PCR
Annotation Date: 2017-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160399
Stage: TS09
Assay Id: MGI:5910584
Age: embryonic day 6.5
Specimen Label: E6.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5910573
Assay Type: RT-PCR
Annotation Date: 2017-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5910584
Age: embryonic day 7.5
Specimen Label: E7.5
Detected: true
Specimen Num: 3
•
•
•
•
•




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