|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 240 for Zp2

0.039s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication
First Author: Lunsford RD
Year: 1990
Journal: Genomics
Title: Genomic mapping of murine Zp-2 and Zp-3, two oocyte-specific loci encoding zona pellucida proteins.
Volume: 6
Issue: 1
Pages: 184-7
Publication
First Author: Julian J
Year: 1994
Journal: Development
Title: Tenascin is induced at implantation sites in the mouse uterus and interferes with epithelial cell adhesion.
Volume: 120
Issue: 3
Pages: 661-71
Publication
First Author: Wassarman PM
Year: 1999
Journal: Cell
Title: Mammalian fertilization: molecular aspects of gamete adhesion, exocytosis, and fusion.
Volume: 96
Issue: 2
Pages: 175-83
Publication
First Author: Watanabe H
Year: 1994
Journal: Nat Genet
Title: Mouse cartilage matrix deficiency (cmd) caused by a 7 bp deletion in the aggrecan gene.
Volume: 7
Issue: 2
Pages: 154-7
Publication  
First Author: Shekels LL
Year: 1995
Journal: Biochem J
Title: Mouse gastric mucin: cloning and chromosomal localization.
Volume: 311 ( Pt 3)
Pages: 775-85
Publication
First Author: Chung WK
Year: 1996
Journal: Genomics
Title: Molecular mapping of the tubby (tub) mutation on mouse chromosome 7.
Volume: 32
Issue: 2
Pages: 210-7
Publication
First Author: Otsuka S
Year: 2008
Journal: Biol Reprod
Title: Oocytes in newborn MRL mouse testes.
Volume: 79
Issue: 1
Pages: 9-16
Publication
First Author: Kozak CA
Year: 1995
Journal: Genomics
Title: Genetic mapping in human and mouse of the locus encoding TRBP, a protein that binds the TAR region of the human immunodeficiency virus (HIV-1).
Volume: 25
Issue: 1
Pages: 66-72
Publication
First Author: Khan AS
Year: 1995
Journal: Genomics
Title: Rat phenol-preferring sulfotransferase genes (Stp and Stp2): localization to mouse chromosomes 7 and 17.
Volume: 26
Issue: 2
Pages: 417-9
Publication
First Author: Choi Y
Year: 2006
Journal: Cell Mol Life Sci
Title: Genetics of early mammalian folliculogenesis.
Volume: 63
Issue: 5
Pages: 579-90
Publication
First Author: Deuve JL
Year: 2015
Journal: Epigenetics
Title: Antagonist Xist and Tsix co-transcription during mouse oogenesis and maternal Xist expression during pre-implantation development calls into question the nature of the maternal imprint on the X chromosome.
Volume: 10
Issue: 10
Pages: 931-42
Publication
First Author: Tonelli Gombalová Z
Year: 2020
Journal: J Comp Neurol
Title: Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.
Volume: 528
Issue: 15
Pages: 2523-2550
Publication
First Author: Brici D
Year: 2017
Journal: Development
Title: Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program.
Volume: 144
Issue: 14
Pages: 2606-2617
Publication
First Author: Zhao LW
Year: 2020
Journal: EMBO Rep
Title: PABPN1L mediates cytoplasmic mRNA decay as a placeholder during the maternal-to-zygotic transition.
Volume: 21
Issue: 8
Pages: e49956
Publication
First Author: Danciger M
Year: 1993
Journal: Genomics
Title: Genetic mapping of three GABAA receptor-subunit genes in the mouse.
Volume: 16
Issue: 2
Pages: 361-5
Publication
First Author: Adamson MC
Year: 1994
Journal: Genomics
Title: Isolation and genetic mapping of two novel members of the murine Wnt gene family, Wnt11 and Wnt12, and the mapping of Wnt5a and Wnt7a.
Volume: 24
Issue: 1
Pages: 9-13
Publication
First Author: Brooker DR
Year: 1995
Journal: Genomics
Title: Epithelial sodium channel genes Scnn1b and Scnn1g are closely linked on distal mouse chromosome 7.
Volume: 29
Issue: 3
Pages: 784-6
Publication
First Author: Yu C
Year: 2016
Journal: Nat Struct Mol Biol
Title: BTG4 is a meiotic cell cycle-coupled maternal-zygotic-transition licensing factor in oocytes.
Volume: 23
Issue: 5
Pages: 387-94
Publication
First Author: Pangas SA
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8.
Volume: 103
Issue: 21
Pages: 8090-5
Publication
First Author: Kato Y
Year: 2019
Journal: EMBO Rep
Title: ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles.
Volume: 20
Issue: 12
Pages: e48251
Publication
First Author: Kwon OJ
Year: 1995
Journal: Mamm Genome
Title: Genetic mapping of five mouse genes encoding synaptotagmins.
Volume: 6
Issue: 12
Pages: 880-1
Publication
First Author: Rajkovic A
Year: 2004
Journal: Science
Title: NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.
Volume: 305
Issue: 5687
Pages: 1157-9
Publication
First Author: Rong Y
Year: 2019
Journal: Nucleic Acids Res
Title: ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.
Volume: 47
Issue: 21
Pages: 11387-11402
Publication
First Author: Toyoda S
Year: 2009
Journal: Dev Biol
Title: Sohlh2 affects differentiation of KIT positive oocytes and spermatogonia.
Volume: 325
Issue: 1
Pages: 238-48
Publication
First Author: Sullivan SL
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: The chromosomal distribution of mouse odorant receptor genes.
Volume: 93
Issue: 2
Pages: 884-8
Publication
First Author: Siracusa LD
Year: 1991
Journal: Genetics
Title: Identification and applications of repetitive probes for gene mapping in the mouse.
Volume: 127
Issue: 1
Pages: 169-79
Publication
First Author: Hamatani T
Year: 2004
Journal: Hum Mol Genet
Title: Age-associated alteration of gene expression patterns in mouse oocytes.
Volume: 13
Issue: 19
Pages: 2263-78
Publication
First Author: Yu C
Year: 2013
Journal: Science
Title: CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.
Volume: 342
Issue: 6165
Pages: 1518-21
Publication
First Author: Kozak CA
Year: 1999
Journal: Mamm Genome
Title: Identification and genetic mapping of differentially expressed genes in mice differing at the If1 interferon regulatory locus.
Volume: 10
Issue: 9
Pages: 853-7
Publication        
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Baibakov B
Year: 2012
Journal: J Cell Biol
Title: Human sperm bind to the N-terminal domain of ZP2 in humanized zonae pellucidae in transgenic mice.
Volume: 197
Issue: 7
Pages: 897-905
Publication
First Author: Sun W
Year: 1999
Journal: Biol Reprod
Title: A contraceptive peptide vaccine targeting sulfated glycoprotein ZP2 of the mouse zona pellucida.
Volume: 60
Issue: 4
Pages: 900-7
Publication
First Author: Avella MA
Year: 2016
Journal: Sci Transl Med
Title: ZP2 peptide beads select human sperm in vitro, decoy mouse sperm in vivo, and provide reversible contraception.
Volume: 8
Issue: 336
Pages: 336ra60
Publication
First Author: Xiong B
Year: 2017
Journal: PLoS Genet
Title: A Unique Egg Cortical Granule Localization Motif Is Required for Ovastacin Sequestration to Prevent Premature ZP2 Cleavage and Ensure Female Fertility in Mice.
Volume: 13
Issue: 1
Pages: e1006580
Interaction Experiment
Description: Interactions between mouse ZP2 glycoprotein and proacrosin; a mechanism for secondary binding of sperm to the zona pellucida during fertilization.
Allele
Name: transgene insertion 2, Jurrien Dean
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Strain
Attribute String: mutant strain, transgenic, coisogenic
Genotype
Symbol: Tg(ZP2)2Dean/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(ZP2)2Dean/? Zp2/Zp2
Background: involves: 129S1/Sv * 129X1/SvJ * CF-1 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 653  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 652  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 312  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 641  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 641  
Fragment?: false
Protein Domain
Type: Domain
Description: The zona pellucida (ZP) domain is a protein polymerisation module of ~260amino acid module, which is found at the C terminus of many secretedeukaryotic glycoproteins that play fundamental roles in development, hearing,immunity, and cancer [, , , ].Proteins containing a ZP domain include:Sperm receptor proteins ZP2 and ZP3. Along with protein ZP1, proteins ZP2and ZP3 are responsible for sperm-adhesion to the zona pellucida. ZP3 firstbinds to specific sperm proteins, thus mediating sperm contacts with theoocyte. ZP2 acts as a second sperm receptor reinforcing the interactions.ZP1 cross-links the polymers formed by ZP2 and ZP3.Zona pellucida sperm-binding protein B (ZP-B) (also known as ZP-X in rabbitand ZP-3 alpha in pig).Glycoprotein GP2, the major component of pancreatic secretory granulemembranes.TGF-beta receptor type III (also known as betaglycan). This protein is aproteoglycan that binds to TGF-beta and could be involved in capturing andretaining TGF-beta for presentation to the signalling receptors.Uromodulin (also known as Tamm-Horsfall urinary glycoprotein). The functionof this protein, which is the most abundant in human urine, is not yetclear.Chicken beta-tectorin, a major glycoprotein of avian tectorial membrane.Most ZP domain proteins are synthesized as precursors with carboxy-terminaltransmembrane domains or glycosyl phosphatidylinositol (GPI) anchors [].The ZP domain contains eight strictly conserved cysteines, which formdisulphide bridges. The disulphide bonds within the ZP domains are divided intotwo groups, suggesting that the ZP domain consists of two subdomains. Inaddition to the conserved cysteines, only a few aromatic or hydrophobic aminoacids are absolutely invariant, probably as a result of structural rather thanfunctional constraints [, , ].
Protein
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
Protein Domain
Type: Conserved_site
Description: The zona pellucida (ZP) domain is a protein polymerisation module of ~260amino acid module, which is found at the C terminus of many secretedeukaryotic glycoproteins that play fundamental roles in development, hearing,immunity, and cancer [, , , ].Proteins containing a ZP domain include:Sperm receptor proteins ZP2 and ZP3. Along with protein ZP1, proteins ZP2and ZP3 are responsible for sperm-adhesion to the zona pellucida. ZP3 firstbinds to specific sperm proteins, thus mediating sperm contacts with theoocyte. ZP2 acts as a second sperm receptor reinforcing the interactions.ZP1 cross-links the polymers formed by ZP2 and ZP3.Zona pellucida sperm-binding protein B (ZP-B) (also known as ZP-X in rabbitand ZP-3 alpha in pig).Glycoprotein GP2, the major component of pancreatic secretory granulemembranes.TGF-beta receptor type III (also known as betaglycan). This protein is aproteoglycan that binds to TGF-beta and could be involved in capturing andretaining TGF-beta for presentation to the signalling receptors.Uromodulin (also known as Tamm-Horsfall urinary glycoprotein). The functionof this protein, which is the most abundant in human urine, is not yetclear.Chicken beta-tectorin, a major glycoprotein of avian tectorial membrane.Most ZP domain proteins are synthesized as precursors with carboxy-terminaltransmembrane domains or glycosyl phosphatidylinositol (GPI) anchors [].The ZP domain contains eight strictly conserved cysteines, which formdisulphide bridges. The disulphide bonds within the ZP domainsare divided intotwo groups, suggesting that the ZP domain consists of two subdomains. Inaddition to the conserved cysteines, only a few aromatic or hydrophobic aminoacids are absolutely invariant, probably as a result of structural rather thanfunctional constraints [, , ].This entry represents a conserved site found within the zona pellucida domain, and includes 2 conserved Cys residues.
Publication
First Author: Vogt EJ
Year: 2019
Journal: Nat Commun
Title: Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis.
Volume: 10
Issue: 1
Pages: 2271
Publication
First Author: Epifano O
Year: 1995
Journal: J Biol Chem
Title: Mouse Zp1 encodes a zona pellucida protein homologous to egg envelope proteins in mammals and fish.
Volume: 270
Issue: 45
Pages: 27254-8
Protein
Organism: Mus musculus/domesticus
Length: 531  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 679  
Fragment?: false
Publication
First Author: Jovine L
Year: 2002
Journal: Nat Cell Biol
Title: The ZP domain is a conserved module for polymerization of extracellular proteins.
Volume: 4
Issue: 6
Pages: 457-61
Protein
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 850  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 713  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 676  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 339  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 177  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 713  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 850  
Fragment?: false
Publication
First Author: Bork P
Year: 1992
Journal: FEBS Lett
Title: A large domain common to sperm receptors (Zp2 and Zp3) and TGF-beta type III receptor.
Volume: 300
Issue: 3
Pages: 237-40
Publication
First Author: Yonezawa N
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Identification of the carboxyl termini of porcine zona pellucida glycoproteins ZPB and ZPC.
Volume: 307
Issue: 4
Pages: 877-82
Publication
First Author: Jovine L
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: A duplicated motif controls assembly of zona pellucida domain proteins.
Volume: 101
Issue: 16
Pages: 5922-7