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Search results 1 to 100 out of 125 for Akap13

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
11214 | AKAP13
Type: gene
Organism: human
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Gene
504288 | AKAP13
Type: gene
Organism: cattle
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Gene
415502 | AKAP13
Type: gene
Organism: chicken
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Gene
327519 | akap13
Type: gene
Organism: zebrafish
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Gene
698172 | AKAP13
Type: gene
Organism: macaque, rhesus
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Gene
100485001 | akap13
Type: gene
Organism: frog, western clawed
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Gene
108190639 | akap13
Type: gene
Organism: zebrafish
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Gene
293024 | Akap13
Type: gene
Organism: rat
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Gene
479032 | AKAP13
Type: gene
Organism: dog, domestic
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Gene
743772 | AKAP13
Type: gene
Organism: chimpanzee
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Protein Domain
IPR028852 | AKAP13
Type: Family
Description: A-kinase anchor protein 13 (AKAP13, also known as AKAP-Lbc) belongs to the AKAP family, which contains functionally related proteins involved in the targeting of the PKA holoenzyme towards specific physiological substrates []. AKAP13 anchors cAMP-dependent protein kinase (PKA) and acts as a guanine nucleotide exchange factor (GEF) that activates the GTPase RhoA []. The Rho-GEF activity of AKAP13 can be inhibited by protein 14-3-3 when it adopts an oligomeric conformation []. AKAP13 has been shown to be essential for cardiac development in mice []. It also plays a role in osteogenesis [].
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Protein Coding Gene
MGI:2676556 | Akap13
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25892096 | J:231357
First Author: Koide H
Year: 2015
Journal: J Bone Miner Res
Title: Mice Deficient in AKAP13 (BRX) Are Osteoporotic and Have Impaired Osteogenesis.
Volume: 30
Issue: 10
Pages: 1887-95
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Publication
20139090 | J:181087
First Author: Mayers CM
Year: 2010
Journal: J Biol Chem
Title: The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice.
Volume: 285
Issue: 16
Pages: 12344-54
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Gene
123466214 | AKAP13-AS1
Type: gene
Organism: human
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Publication
24161911 | J:238039
 
First Author: Taglieri DM
Year: 2014
Journal: J Mol Cell Cardiol
Title: The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy.
Volume: 66
Pages: 27-40
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Publication
23658642 | J:231257
First Author: Spindler MJ
Year: 2013
Journal: PLoS One
Title: AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophy.
Volume: 8
Issue: 4
Pages: e62705
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Protein
Q9D9W9
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
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Protein
Q924X9
Organism: Mus musculus/domesticus
Length: 934  
Fragment?: true
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Protein
A0A668KL88
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: true
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Protein
A0A140LID7
Organism: Mus musculus/domesticus
Length: 569  
Fragment?: true
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Protein
Q3T998
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: true
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Protein
A0A140LHQ3
Organism: Mus musculus/domesticus
Length: 423  
Fragment?: true
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Protein
A0A140LIX0
Organism: Mus musculus/domesticus
Length: 870  
Fragment?: true
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Protein
Q3TR80
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: false
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Publication
11546812 | -
First Author: Diviani D
Year: 2001
Journal: J Biol Chem
Title: AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation.
Volume: 276
Issue: 47
Pages: 44247-57
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Publication
16460837 | -
First Author: Diviani D
Year: 2006
Journal: Eur J Cell Biol
Title: AKAP-Lbc: a molecular scaffold for the integration of cyclic AMP and Rho transduction pathways.
Volume: 85
Issue: 7
Pages: 603-10
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Protein
Q3TA34
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: true
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Protein
Q3TZA8
Organism: Mus musculus/domesticus
Length: 360  
Fragment?: true
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Protein
Q8BYV7
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: false
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Protein
E9Q394
Organism: Mus musculus/domesticus
Length: 2776  
Fragment?: false
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Protein
A0A140LJJ5
Organism: Mus musculus/domesticus
Length: 2794  
Fragment?: false
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Protein
Q3UZK5
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: true
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Protein
A0A140LHG3
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: true
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Publication
26192751 | J:244762
First Author: Johnson KR
Year: 2015
Journal: PLoS One
Title: Genome-Wide Gene Expression Analysis Shows AKAP13-Mediated PKD1 Signaling Regulates the Transcriptional Response to Cardiac Hypertrophy.
Volume: 10
Issue: 7
Pages: e0132474
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Protein Coding Gene
MGP_CAROLIEiJ_G0029865 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032374 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032353 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032289 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032365 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032078 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2676556 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032857 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031406 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032044 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032199 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032154 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032280 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032191 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031126 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031524 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013087 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030967 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1731775 | J:11574
First Author: Tsuchiya T
Year: 1992
Journal: Biochem Biophys Res Commun
Title: In vitro reconstitution of an erythropoietin gene transcription system using its 5'-flanking sequence and a nuclear extract from anemic kidney.
Volume: 182
Issue: 1
Pages: 137-43
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GXD Expression
GXD Expression
   
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Specimen Label: Heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Specimen Label: Brain
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Specimen Label: Spleen
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Specimen Label: Lung
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Specimen Label: Liver
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5816285
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5816468
Age: embryonic day 9.0-9.5
Image: 1
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5816285
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5816468
Age: embryonic day 9.0-9.5
Image: 1
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5816285
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5816468
Age: embryonic day 9.0-9.5
Image: 1
Specimen Label: 5
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5816285
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5816468
Age: embryonic day 9.0-9.5
Image: 1
Specimen Label: 7
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:5816287
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610514
Stage: TS14
Assay Id: MGI:5816485
Age: embryonic day 9.0
Image: 6
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5816287
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610514
Stage: TS14
Assay Id: MGI:5816485
Age: embryonic day 9.0
Image: 6
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5816287
Assay Type: RT-PCR
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610514
Stage: TS14
Assay Id: MGI:5816485
Age: embryonic day 9.0
Image: 6
Specimen Label: -/-
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5816470
Age: embryonic day 9.0-9.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5816470
Age: embryonic day 9.0-9.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3268815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5816470
Age: embryonic day 9.0-9.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3268815
Stage: TS15
Assay Id: MGI:5816470
Age: embryonic day 9.0-9.5
Image: 2F
Specimen Label: 2F
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3268828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5816470
Age: postnatal adult
Image: S2A
Specimen Label: S2A
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5816470
Age: postnatal adult
Image: S2C
Note: Expression is localized to sarcomeres.
Specimen Label: S2C
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268816
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:5816487
Age: embryonic day 9.5-10.0
Image: S2E
Note: Expression is at the Z-discs of sarcomeres.
Specimen Label: S2E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1610517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5816470
Age: embryonic day 10.0-10.5
Image: 2G
Specimen Label: 2G
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:5816470
Age: embryonic day 10.0-10.5
Image: 2H
Specimen Label: 2H
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5816294
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5816470
Age: embryonic day 9.0-9.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 1
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Publication
16469733 | J:111574
First Author: Kino T
Year: 2006
Journal: J Biol Chem
Title: Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system.
Volume: 281
Issue: 14
Pages: 9118-26
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Publication
19211510 | J:181088
First Author: Kino T
Year: 2009
Journal: Sci Signal
Title: Brx mediates the response of lymphocytes to osmotic stress through the activation of NFAT5.
Volume: 2
Issue: 57
Pages: ra5
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Publication
23716597 | J:204574
First Author: Pérez López I
Year: 2013
Journal: Mol Cell Biol
Title: A-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophy.
Volume: 33
Issue: 15
Pages: 2903-17
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Publication
29298866 | J:254437
 
First Author: Serr I
Year: 2018
Journal: Sci Transl Med
Title: A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes.
Volume: 10
Issue: 422
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Publication
31541165 | J:284228
First Author: Ikegami K
Year: 2019
Journal: Sci Rep
Title: Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice.
Volume: 9
Issue: 1
Pages: 13634
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Publication
26921296 | J:244712
First Author: Navarro N
Year: 2016
Journal: G3 (Bethesda)
Title: Does 3D Phenotyping Yield Substantial Insights in the Genetics of the Mouse Mandible Shape?
Volume: 6
Issue: 5
Pages: 1153-63
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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