Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Sibbe M |
Year: |
2013 |
Journal: |
Neurosci Lett |
Title: |
Region-specific expression of Dickkopf-like1 in the adult brain. Abbreviated title: Dkkl1 in the adult brain. |
Volume: |
535 |
|
Pages: |
84-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kohn MJ |
Year: |
2005 |
Journal: |
Mol Reprod Dev |
Title: |
DkkL1 (Soggy), a Dickkopf family member, localizes to the acrosome during mammalian spermatogenesis. |
Volume: |
71 |
Issue: |
4 |
Pages: |
516-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhuang XJ |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
SLXL1, a novel acrosomal protein, interacts with DKKL1 and is involved in fertilization in mice. |
Volume: |
6 |
Issue: |
6 |
Pages: |
e20866 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kohn MJ |
Year: |
2010 |
Journal: |
Fertil Steril |
Title: |
The acrosomal protein Dickkopf-like 1 (DKKL1) facilitates sperm penetration of the zona pellucida. |
Volume: |
93 |
Issue: |
5 |
Pages: |
1533-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaneko KJ |
Year: |
2010 |
Journal: |
Fertil Steril |
Title: |
The acrosomal protein Dickkopf-like 1 (DKKL1) is not essential for fertility. |
Volume: |
93 |
Issue: |
5 |
Pages: |
1526-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dakhova O |
Year: |
2009 |
Journal: |
Endocrinology |
Title: |
Dickkopf-like1 regulates postpubertal spermatocyte apoptosis and testosterone production. |
Volume: |
150 |
Issue: |
1 |
Pages: |
404-12 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4439102 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-04-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3568928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:4439103 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Placenta |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4439102 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-04-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3568928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:4439103 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
Placenta |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4439102 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-04-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610915 |
|
Stage: |
TS15 |
Assay Id: |
MGI:4439103 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Yolk Sac |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4439102 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-04-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610920 |
|
Stage: |
TS20 |
Assay Id: |
MGI:4439103 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
Amnion |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4439102 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-04-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1606511 |
|
Stage: |
TS11 |
Assay Id: |
MGI:4439103 |
Age: |
embryonic day 7.5 |
|
|
Specimen Label: |
Embryo |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4439102 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-04-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603911 |
|
Stage: |
TS11 |
Assay Id: |
MGI:4439103 |
Age: |
embryonic day 7.5 |
|
|
Specimen Label: |
Embryo |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4439102 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-04-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603915 |
|
Stage: |
TS15 |
Assay Id: |
MGI:4439103 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Embryo |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4439102 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-04-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604215 |
|
Stage: |
TS15 |
Assay Id: |
MGI:4439103 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Yolk Sac |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4439102 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-04-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604220 |
|
Stage: |
TS20 |
Assay Id: |
MGI:4439103 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
Chorion |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4439102 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-04-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604611 |
|
Stage: |
TS11 |
Assay Id: |
MGI:4439103 |
Age: |
embryonic day 7.5 |
|
|
Specimen Label: |
Trophectoderm |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Ambiguous |
Sex: |
Male |
Emaps: |
EMAPS:1868128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691537 |
Age: |
postnatal adult |
Image: |
BCM_1467386 |
Note: |
vas deferens |
Specimen Label: |
BCM_1467386 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691537 |
Age: |
postnatal adult |
Image: |
BCM_1467386 |
|
Specimen Label: |
BCM_1467386 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Krupnik VE |
Year: |
1999 |
Journal: |
Gene |
Title: |
Functional and structural diversity of the human Dickkopf gene family. |
Volume: |
238 |
Issue: |
2 |
Pages: |
301-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaneko KJ |
Year: |
2000 |
Journal: |
Nucleic Acids Res |
Title: |
Soggy, a spermatocyte-specific gene, lies 3.8 kb upstream of and antipodal to TEAD-2, a transcription factor expressed at the beginning of mouse development. |
Volume: |
28 |
Issue: |
20 |
Pages: |
3982-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaneko KJ |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
DNA methylation may restrict but does not determine differential gene expression at the Sgy/Tead2 locus during mouse development. |
Volume: |
24 |
Issue: |
5 |
Pages: |
1968-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reynard LN |
Year: |
2009 |
Journal: |
Biol Reprod |
Title: |
The multi-copy mouse gene Sycp3-like Y-linked (Sly) encodes an abundant spermatid protein that interacts with a histone acetyltransferase and an acrosomal protein. |
Volume: |
81 |
Issue: |
2 |
Pages: |
250-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seitz R |
Year: |
2018 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Cross-Inhibition of Norrin and TGF-β Signaling Modulates Development of Retinal and Choroidal Vasculature. |
Volume: |
59 |
Issue: |
6 |
Pages: |
2240-2251 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bennett CN |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Regulation of Wnt signaling during adipogenesis. |
Volume: |
277 |
Issue: |
34 |
Pages: |
30998-1004 |
|
•
•
•
•
•
|
Publication |
First Author: |
Perdigoto CN |
Year: |
2016 |
Journal: |
PLoS Genet |
Title: |
Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. |
Volume: |
12 |
Issue: |
7 |
Pages: |
e1006151 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shalom-Barak T |
Year: |
2012 |
Journal: |
Dev Biol |
Title: |
Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. |
Volume: |
372 |
Issue: |
1 |
Pages: |
143-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
Year: |
2001 |
|
Title: |
LocusLink Collaboration |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Mouse Synonym Curation |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
230
|
Fragment?: |
false |
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•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
183
|
Fragment?: |
false |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
219
|
Fragment?: |
true |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
230
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Fragment?: |
false |
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•
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Publication |
First Author: |
Patel S |
Year: |
2018 |
Journal: |
J Biol Chem |
Title: |
Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins. |
Volume: |
293 |
Issue: |
31 |
Pages: |
12149-12166 |
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Protein Domain |
Type: |
Family |
Description: |
This entry includes Dickkopf-related proteins 1-4 (DKK1-4) and Dickkopf-like protein 1 (DKKL1). The Dickkopf (Dkk) proteins are cysteine-rich secretory proteins and highly conserved inhibitors of the canonical Wnt signaling pathway, which play key roles in many essential biological processes []. DKKL1 is a acrosomal protein that affects in vitro fertilization, but the effect is attenuated in vivo []. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
259
|
Fragment?: |
false |
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•
•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
272
|
Fragment?: |
false |
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•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
349
|
Fragment?: |
false |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
221
|
Fragment?: |
false |
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•
•
•
•
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