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Search results 1101 to 1194 out of 1194 for Nrp1

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Type Details Score
Publication      
First Author: Elliott R
Year: 2000
Journal: Personal Communication
Title: Chromosome Locations Based on RH mapping
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Oeschger FM
Year: 2012
Journal: Cereb Cortex
Title: Gene expression analysis of the embryonic subplate.
Volume: 22
Issue: 6
Pages: 1343-59
Publication
First Author: Memic F
Year: 2018
Journal: Gastroenterology
Title: Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Volume: 154
Issue: 3
Pages: 624-636
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Mehta V
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: VEGF (Vascular Endothelial Growth Factor) Induces NRP1 (Neuropilin-1) Cleavage via ADAMs (a Disintegrin and Metalloproteinase) 9 and 10 to Generate Novel Carboxy-Terminal NRP1 Fragments That Regulate Angiogenic Signaling.
Volume: 38
Issue: 8
Pages: 1845-1858
Allele
Name: neuropilin 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
GXD Expression
Probe: MGI:5447971
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3660522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7481906
Age: embryonic day 14.5
Image: 2B CTIP2 (middle-right)
Note: Expression in subcerebral projection neurons constituting the corticospinal tract. Expression overlapping with Nrp1 expression.
Specimen Label: 2B CTIP2 (middle-right)
Detected: true
Specimen Num: 3
Interaction Experiment
Description: USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells.
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Vincent Cavailles
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Zhao J
Year: 2023
Journal: Cell Death Dis
Title: USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells.
Volume: 14
Issue: 1
Pages: 40
Allele
Name: neuropilin 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Genotype
Symbol: Hprt1/?
Background: involves: 129 * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Hprt1/Hprt1<+>
Background: involves: 129 * C57BL/6
Zygosity: ht
Has Mutant Allele: true
UniProt Feature
Begin: 278
Description: Found in Nmf249 mice, a Charcot-Marie-Tooth 2D model; involved in neuromuscular dysfunction; contrary to the wild-type protein, strongly interacts with NRP1 and competes with VEGFA for NRP1-binding; no effect on subcellular location.
Type: sequence variant
End: 278
Publication
First Author: Reynaud A
Year: 2001
Journal: Yeast
Title: Disruption and functional analysis of six ORFs of chromosome IV: YDL103c (QRI1), YDL105w (QRI2), YDL112w (TRM3), YDL113c, YDL116w (NUP84) and YDL167c (NRP1).
Volume: 18
Issue: 3
Pages: 273-82
Protein Domain
Type: Domain
Description: This domain is found at the N-terminal of Nuclear speckle splicing regulatory protein 1 (NRP1, also known as Nuclear speckle-related protein 70 and Coiled-coil domain-containing protein 55) and contains a coiled-coil domain that plays a critical role in NRP1 alternative splicing activity and self-oligomerization. NRP1 is a RNA-binding protein that mediates pre-mRNA alternative splicing regulation [, ].
Protein Domain
Type: Domain
Description: This entry represents the RNA recognition motif (RRM) of Nrp1 [], which contains an RNA recognition motif (RRM), two Ran-binding protein zinc fingers (Znf-RanBP), and an asparagine-rich region. The function of Nrp1 is not clear. It may be involved in ribosome biogenesis [].
Strain
Attribute String: coisogenic, targeted mutation, mutant strain
Publication
First Author: Wade CH
Year: 2006
Journal: Yeast
Title: The budding yeast rRNA and ribosome biosynthesis (RRB) regulon contains over 200 genes.
Volume: 23
Issue: 4
Pages: 293-306
Protein Domain
Type: Domain
Description: This domain found at the C-terminal of Nuclear speckle splicing regulatory protein 1 (NRP1, also known as Nuclear speckle-related protein 70 and Coiled-coil domain-containing protein 55) from mammals and aves. This is the RS-like domain, that resembles the arginine/serine-rich (RS) domain in other SR proteins, interacts with two SR proteins and with target mRNA, being essential for NRP1 activity. NRP1 is a RNA-binding protein that mediates pre-mRNA alternative splicing regulation [, ].
Publication
First Author: Kim YD
Year: 2011
Journal: Nucleic Acids Res
Title: NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo.
Volume: 39
Issue: 10
Pages: 4300-14
Protein
Organism: Mus musculus/domesticus
Length: 542  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 403  
Fragment?: true
Publication
First Author: Kim CH
Year: 2016
Journal: J Biol Chem
Title: Nuclear Speckle-related Protein 70 Binds to Serine/Arginine-rich Splicing Factors 1 and 2 via an Arginine/Serine-like Region and Counteracts Their Alternative Splicing Activity.
Volume: 291
Issue: 12
Pages: 6169-81
Publication
First Author: Fu Q
Year: 2010
Journal: Mol Cells
Title: Identification of an Arabidopsis Nodulin-related protein in heat stress.
Volume: 29
Issue: 1
Pages: 77-84
Protein Domain
Type: Family
Description: Nodulin-related protein 1 (NRP1) may play a role in the negative-feedback regulation of the abscisic acid (ABA) synthesis pathway. Overexpression of NRP1 enhanced susceptibility to heat stress and was accompanied of decreased accumulation of ABA after heat treatment []. The function of NRP2 is not clear.
Publication
First Author: Lapierre M
Year: 2014
Journal: J Clin Invest
Title: RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis.
Volume: 124
Issue: 5
Pages: 1899-913
Protein
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: true
Publication  
First Author: Romi E
Year: 2014
Journal: Nat Commun
Title: ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A.
Volume: 5
Pages: 4058
Publication
First Author: Mo Z
Year: 2018
Journal: Nat Commun
Title: Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy.
Volume: 9
Issue: 1
Pages: 1007
Publication
First Author: Snuderl M
Year: 2013
Journal: Cell
Title: Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma.
Volume: 152
Issue: 5
Pages: 1065-76
Publication
First Author: Sörensen I
Year: 2009
Journal: Blood
Title: DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries.
Volume: 113
Issue: 22
Pages: 5680-8
Publication
First Author: Bielenberg DR
Year: 2012
Journal: Am J Pathol
Title: Increased smooth muscle contractility in mice deficient for neuropilin 2.
Volume: 181
Issue: 2
Pages: 548-59
Publication
First Author: Andrews WD
Year: 2016
Journal: J Comp Neurol
Title: Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice.
Volume: 524
Issue: 3
Pages: 518-34
Publication
First Author: Yamamizu K
Year: 2011
Journal: Blood
Title: The κ opioid system regulates endothelial cell differentiation and pathfinding in vascular development.
Volume: 118
Issue: 3
Pages: 775-85
Publication  
First Author: Lim KH
Year: 2021
Journal: Front Genet
Title: Identifying New COVID-19 Receptor Neuropilin-1 in Severe Alzheimer's Disease Patients Group Brain Using Genome-Wide Association Study Approach.
Volume: 12
Pages: 741175
Publication
First Author: Long JB
Year: 2009
Journal: Dev Biol
Title: VEGF-A and Semaphorin3A: modulators of vascular sympathetic innervation.
Volume: 334
Issue: 1
Pages: 119-32
Publication
First Author: Gehrmann U
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.
Volume: 116
Issue: 51
Pages: 25839-25849
Publication
First Author: Ruhrberg C
Year: 2002
Journal: Genes Dev
Title: Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis.
Volume: 16
Issue: 20
Pages: 2684-98
Publication
First Author: Dang P
Year: 2012
Journal: J Neurosci
Title: TAG1 regulates the endocytic trafficking and signaling of the semaphorin3A receptor complex.
Volume: 32
Issue: 30
Pages: 10370-82
Publication
First Author: Zheng Y
Year: 2022
Journal: Cell Death Differ
Title: Regulation of Semaphorin3A in the process of cutaneous wound healing.
Volume: 29
Issue: 10
Pages: 1941-1954
Publication  
First Author: Gemmill RM
Year: 2017
Journal: Sci Signal
Title: The neuropilin 2 isoform NRP2b uniquely supports TGFβ-mediated progression in lung cancer.
Volume: 10
Issue: 462
Publication
First Author: McGowan SE
Year: 2020
Journal: Am J Respir Cell Mol Biol
Title: Platelet-derived Growth Factor-α and Neuropilin-1 Mediate Lung Fibroblast Response to Rigid Collagen Fibers.
Volume: 62
Issue: 4
Pages: 454-465
Publication
First Author: Krilleke D
Year: 2007
Journal: J Biol Chem
Title: Molecular mapping and functional characterization of the VEGF164 heparin-binding domain.
Volume: 282
Issue: 38
Pages: 28045-56
Publication
First Author: Boscolo E
Year: 2011
Journal: Am J Pathol
Title: VEGFR-1 mediates endothelial differentiation and formation of blood vessels in a murine model of infantile hemangioma.
Volume: 179
Issue: 5
Pages: 2266-77
Publication
First Author: Jahnsen ED
Year: 2015
Journal: PLoS One
Title: Notch1 is pan-endothelial at the onset of flow and regulated by flow.
Volume: 10
Issue: 4
Pages: e0122622
Publication
First Author: Blondeau A
Year: 2016
Journal: Neural Dev
Title: Dual leucine zipper kinase regulates expression of axon guidance genes in mouse neuronal cells.
Volume: 11
Issue: 1
Pages: 13
Publication
First Author: Sharifpanah F
Year: 2016
Journal: Biochim Biophys Acta
Title: Mechanical strain stimulates vasculogenesis and expression of angiogenesis guidance molecules of embryonic stem cells through elevation of intracellular calcium, reactive oxygen species and nitric oxide generation.
Volume: 1863
Issue: 12
Pages: 3096-3105
Publication
First Author: Zhang Y
Year: 2015
Journal: Sci Signal
Title: DDR2 (discoidin domain receptor 2) suppresses osteoclastogenesis and is a potential therapeutic target in osteoporosis.
Volume: 8
Issue: 369
Pages: ra31
Publication
First Author: Lee PS
Year: 2019
Journal: Diabetes
Title: Opposing Effects of Neuropilin-1 and -2 on Sensory Nerve Regeneration in Wounded Corneas: Role of Sema3C in Ameliorating Diabetic Neurotrophic Keratopathy.
Volume: 68
Issue: 4
Pages: 807-818
Publication
First Author: de Barros SC
Year: 2020
Journal: J Immunol
Title: Pleiotropic Roles of VEGF in the Microenvironment of the Developing Thymus.
Volume: 205
Issue: 9
Pages: 2423-2436
Publication
First Author: Loeffler I
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Erythropoietin ameliorates podocyte injury in advanced diabetic nephropathy in the db/db mouse.
Volume: 305
Issue: 6
Pages: F911-8
Publication
First Author: Tatura R
Year: 2015
Journal: Immunology
Title: Relevance of Foxp3⁺ regulatory T cells for early and late phases of murine sepsis.
Volume: 146
Issue: 1
Pages: 144-56
Publication  
First Author: Tezuka K
Year: 2018
Journal: J Virol
Title: Control of Human T-Cell Leukemia Virus Type 1 (HTLV-1) Infection by Eliminating Envelope Protein-Positive Cells with Recombinant Vesicular Stomatitis Viruses Encoding HTLV-1 Primary Receptor.
Volume: 92
Issue: 4
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7