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Search results 101 to 168 out of 168 for Borcs6

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0.022s
Type Details Score
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3271628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373788
Specimen Label: JAX_1373788
Detected: true
Specimen Num: 41
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373801
Specimen Label: JAX_1373801
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373811
Specimen Label: JAX_1373811
Detected: true
Specimen Num: 19
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Widespread
Stage: TS04
Assay Id: MGI:7398478
Age: embryonic day 3.5
Image: 1a (heterozygous)
Specimen Label: 1a (heterozygous)
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160466
Pattern: Widespread
Stage: TS06
Assay Id: MGI:7398478
Age: embryonic day 4.5
Image: 1f
Note: Expression in throughout embryo, both in trophectoderm and inner cell mass.
Specimen Label: 1f
Detected: true
Specimen Num: 5
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-12-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160507
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7398478
Age: embryonic day 5.5
Image: 1b
Note: Less expression in epiblast .
Specimen Label: 1b
Detected: true
Specimen Num: 2
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160506
Pattern: Widespread
Stage: TS06
Assay Id: MGI:7398478
Age: embryonic day 4.5
Image: 1f
Note: Expression in throughout embryo, both in trophectoderm and inner cell mass.
Specimen Label: 1f
Detected: true
Specimen Num: 5
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-12-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160507
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7398478
Age: embryonic day 5.5
Image: 1g
Note: Expression in epiblast.
Specimen Label: 1g
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3590528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373775
Specimen Label: JAX_1373775
Detected: true
Specimen Num: 28
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373796
Specimen Label: JAX_1373796
Detected: true
Specimen Num: 49
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373795
Specimen Label: JAX_1373795
Detected: true
Specimen Num: 48
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373776
Specimen Label: JAX_1373776
Detected: true
Specimen Num: 29
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3592628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373810
Specimen Label: JAX_1373810
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373782
Specimen Label: JAX_1373782
Detected: true
Specimen Num: 35
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373789
Specimen Label: JAX_1373789
Detected: true
Specimen Num: 42
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160517
Pattern: Regionally restricted
Stage: TS07
Assay Id: MGI:7398478
Age: embryonic day 5.5
Image: 1b
Note: Robust expression in visceral endoderm. Less expression in distal half of visceral endoderm.
Specimen Label: 1b
Detected: true
Specimen Num: 2
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:7398478
Age: embryonic day 6.5
Image: 1c
Note: Expression in distal half of visceral endoderm.
Specimen Label: 1c
Detected: true
Specimen Num: 3
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1605111
Pattern: Widespread
Stage: TS11
Assay Id: MGI:7398478
Age: embryonic day 7.5
Image: 1d
Note: Expression throughout extraembryonic ectoderm and visceral endoderm.
Specimen Label: 1d
Detected: true
Specimen Num: 4
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160517
Pattern: Regionally restricted
Stage: TS07
Assay Id: MGI:7398478
Age: embryonic day 5.5
Image: 1g
Note: Expression in distal half of visceral endoderm.
Specimen Label: 1g
Detected: true
Specimen Num: 6
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:7398478
Age: embryonic day 6.5
Image: 1h
Note: Expression in distal half of visceral endoderm.
Specimen Label: 1h
Detected: true
Specimen Num: 7
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-12-08
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1605111
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:7398478
Age: embryonic day 7.5
Image: 1i
Note: Sparce expression in distal half of visceral endoderm.
Specimen Label: 1i
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:7398452
Assay Type: RNA in situ
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1605111
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:7398479
Age: embryonic day 7.5
Image: 1e
Note: Authors report pattern of expression as seen for knock-in reporter.
Specimen Label: 1e
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373813
Specimen Label: JAX_1373813
Detected: true
Specimen Num: 21
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:360409
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:6362861
Age: embryonic day 6.5
Image: E6.5
Specimen Label: E6.5
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:360409
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:6362861
Age: embryonic day 6.5
Image: E6.5 - section
Specimen Label: E6.5 - section
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3604011
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6362861
Age: embryonic day 7.5
Image: E7.5
Specimen Label: E7.5
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3604011
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6362861
Age: embryonic day 7.5
Image: E7.5 - section
Specimen Label: E7.5 - section
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3604013
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:6362861
Age: embryonic day 8.5
Image: E8.5
Specimen Label: E8.5
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3604013
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:6362861
Age: embryonic day 8.5
Image: E8.5 - section a
Specimen Label: E8.5 - section a
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3604013
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:6362861
Age: embryonic day 8.5
Image: E8.5 - section b
Specimen Label: E8.5 - section b
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373819
Specimen Label: JAX_1373819
Detected: true
Specimen Num: 27
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373815
Specimen Label: JAX_1373815
Detected: true
Specimen Num: 23
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691983
Age: postnatal adult
Image: JAX_1373777
Specimen Label: JAX_1373777
Detected: true
Specimen Num: 30
Publication
First Author: Yordanov TE
Year: 2019
Journal: Traffic
Title: Biogenesis of lysosome-related organelles complex-1 (BORC) regulates late endosomal/lysosomal size through PIKfyve-dependent phosphatidylinositol-3,5-bisphosphate.
Volume: 20
Issue: 9
Pages: 674-696
Publication
First Author: Kälin S
Year: 2017
Journal: Cell Metab
Title: A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function.
Volume: 26
Issue: 3
Pages: 475-492.e7
Publication      
First Author: Mager J
Year: 2019
Journal: MGI Direct Data Submission
Title: A Catalog of Early Lethal KOMP Phenotypes
Publication
First Author: Suzuki H
Year: 2001
Journal: Genome Res
Title: Protein-protein interaction panel using mouse full-length cDNAs.
Volume: 11
Issue: 10
Pages: 1758-65
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication
First Author: Araki M
Year: 2021
Journal: Hum Mol Genet
Title: BORCS6 is involved in the enlargement of lung lamellar bodies in Lrrk2 knockout mice.
Volume: 30
Issue: 17
Pages: 1618-1631
Protein Domain
Type: Domain
Description: This entry represents a domain found in proteins conserved from nematodes to humans. Members include BORCS6 (BLOC-1-related complex subunit 6) also known as Lyspersin (lysosome-dispersing protein) or C17orf59. It constitutes sub-unit 6 of the BORC complex (BLOC-one-related complex). BORC is a multisubunit complex that regulates the positioning of lysosomes at the cell periphery, and consequently affects cell migration. BORC associates with the lysosomal membrane, where it functions to recruit the small GTPase Arl8. This initiates a series of interactions that promote the microtubule-guided transport of lysosomes toward the cell periphery [, ]. This domain is located at the C-terminal end of most proteins and forms an α- helix according to structure predictions.