This entry represents Cadm4, which belongs to a group of nectin-like cell adhesion molecules, Cadm1-4 (also known as NECL1-4). They are adhesion molecules that engage in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation [, , ]. It has been shown that Cadm4 plays a role in the establishment of the myelin unit in the peripheral nervous system [].