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Search results 201 to 300 out of 300 for Paics

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0.056s
Type Details Score
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_04
Specimen Label: euxassay_018936_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_05
Specimen Label: euxassay_018936_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_06
Specimen Label: euxassay_018936_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_07
Specimen Label: euxassay_018936_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_08
Specimen Label: euxassay_018936_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_09
Specimen Label: euxassay_018936_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_12
Specimen Label: euxassay_018936_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_17
Specimen Label: euxassay_018936_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_18
Specimen Label: euxassay_018936_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_19
Specimen Label: euxassay_018936_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1683322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Image: ES977; Specimen S379
Specimen Label: ES977; Specimen S379
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1700022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Image: ES977; Specimen S379
Specimen Label: ES977; Specimen S379
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1832122
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2891920
Stage: TS20
Assay Id: MGI:5540781
Age: embryonic day 12.5
Image: GUDMAP:8022
Specimen Label: GUDMAP:8022
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:2759917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5540781
Age: embryonic day 10.5
Image: GUDMAP:8018
Specimen Label: GUDMAP:8018
Specimen Num: 1
GXD Expression
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1876522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Image: ES977; Specimen S379
Note: Expression was weak in the immune system.
Specimen Label: ES977; Specimen S379
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:2851820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540781
Age: embryonic day 12.5
Image: GUDMAP:8020
Note: signal weak or absent
Specimen Label: GUDMAP:8020
Specimen Num: 3
GXD Expression    
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2914320
Stage: TS20
Assay Id: MGI:5540781
Age: embryonic day 12.5
Image: GUDMAP:8019
Specimen Label: GUDMAP:8019
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1795320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540781
Age: embryonic day 12.5
Image: GUDMAP:8020
Specimen Label: GUDMAP:8020
Specimen Num: 3
GXD Expression  
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:1795320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540781
Age: embryonic day 12.5
Image: GUDMAP:8021
Note: signal is weak or absent
Specimen Label: GUDMAP:8021
Specimen Num: 4
GXD Expression  
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1741222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Image: ES977; Specimen S379
Specimen Label: ES977; Specimen S379
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754022
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3599822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Image: ES977; Specimen S379
Specimen Label: ES977; Specimen S379
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540781
Age: embryonic day 12.5
Image: GUDMAP:8020
Specimen Label: GUDMAP:8020
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2760520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540781
Age: embryonic day 12.5
Image: GUDMAP:8021
Specimen Label: GUDMAP:8021
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1737517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5540781
Age: embryonic day 10.5
Image: GUDMAP:8018
Specimen Label: GUDMAP:8018
Specimen Num: 1
GXD Expression  
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3280922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Image: ES977; Specimen S379
Specimen Label: ES977; Specimen S379
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3287022
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Image: ES977; Specimen S379
Specimen Label: ES977; Specimen S379
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:3087020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540781
Age: embryonic day 12.5
Image: GUDMAP:8021
Specimen Label: GUDMAP:8021
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821522
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3557722
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Image: ES977; Specimen S379
Specimen Label: ES977; Specimen S379
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2892420
Stage: TS20
Assay Id: MGI:5540781
Age: embryonic day 12.5
Image: GUDMAP:8022
Specimen Label: GUDMAP:8022
Detected: false
Specimen Num: 5
GXD Expression  
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Image: ES977; Specimen S379
Specimen Label: ES977; Specimen S379
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1802422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Image: ES977; Specimen S379
Specimen Label: ES977; Specimen S379
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_09
Specimen Label: euxassay_018936_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_10
Specimen Label: euxassay_018936_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_15
Specimen Label: euxassay_018936_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4427977
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827027
Age: embryonic day 14.5
Image: euxassay_018936_16
Specimen Label: euxassay_018936_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4845970
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5540781
Age: embryonic day 12.5
Image: GUDMAP:8022
Specimen Label: GUDMAP:8022
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309703
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5423045
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: ES977; Specimen S379
Detected: false
Specimen Num: 1
Publication    
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, RIKEN cDNA 2610511I09 gene, clone MGC: 25530 IMAGE: 3586809, mRNA, complete cds
Pages: BC018153
Publication
First Author: Lastwika KJ
Year: 2016
Journal: Cancer Res
Title: Control of PD-L1 Expression by Oncogenic Activation of the AKT-mTOR Pathway in Non-Small Cell Lung Cancer.
Volume: 76
Issue: 2
Pages: 227-38
Publication
First Author: Baresova V
Year: 2016
Journal: Mol Genet Metab
Title: CRISPR-Cas9 induced mutations along de novo purine synthesis in HeLa cells result in accumulation of individual enzyme substrates and affect purinosome formation.
Volume: 119
Issue: 3
Pages: 270-277
Publication  
First Author: Mizukoshi T
Year: 2023
Journal: eNeuro
Title: Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development.
Volume: 10
Issue: 10
Publication
First Author: Lepourcelet M
Year: 2005
Journal: Development
Title: Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF).
Volume: 132
Issue: 2
Pages: 415-27
Publication
First Author: Combes AN
Year: 2009
Journal: Dev Dyn
Title: Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.
Volume: 238
Issue: 5
Pages: 1033-41
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
Publication
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
Publication        
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication        
First Author: Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas
Year: 2023
Title: TreeGrafter-generated GO annotations
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein Domain
Type: Domain
Description: The novo purine biosynthesis proceeds by two divergent paths. In bacteria, yeasts, and plants, 5-aminoimidazole ribonucleotide (AIR) is converted to 4-carboxy-AIR (CAIR) by two enzymes: N5-carboxy-AIR (N5-CAIR) synthetase (PurK) and N5-CAIR mutase (class I PurE). In animals, the conversion of AIR to CAIR requires a single enzyme, AIR carboxylase (class II PurE) []. Class I and class II PurEs are mechanistically related but bind different substrates. In yeast and plants PurE is found in PurK-class I PurE fusion proteins, known as ADE2 [, ], while animal class II PurEs are found in PurC-PurE fusion proteins, also known as ADE2 or PAICS [].
Publication
First Author: Firestine SM
Year: 1994
Journal: Biochemistry
Title: Reactions catalyzed by 5-aminoimidazole ribonucleotide carboxylases from Escherichia coli and Gallus gallus: a case for divergent catalytic mechanisms.
Volume: 33
Issue: 39
Pages: 11927-34
Publication
First Author: Firestine SM
Year: 1998
Journal: Arch Biochem Biophys
Title: Biochemical role of the Cryptococcus neoformans ADE2 protein in fungal de novo purine biosynthesis.
Volume: 351
Issue: 1
Pages: 123-34
Publication
First Author: Firestine SM
Year: 1994
Journal: Biochemistry
Title: Carboxylases in de novo purine biosynthesis. Characterization of the Gallus gallus bifunctional enzyme.
Volume: 33
Issue: 39
Pages: 11917-26
Publication
First Author: Chapman KA
Year: 1994
Journal: Plant Mol Biol
Title: Structural organization of de novo purine biosynthesis enzymes in plants: 5-aminoimidazole ribonucleotide carboxylase and 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase cDNAs from Vigna aconitifolia.
Volume: 24
Issue: 2
Pages: 389-95
Publication
First Author: Mueller EJ
Year: 1994
Journal: Biochemistry
Title: N5-carboxyaminoimidazole ribonucleotide: evidence for a new intermediate and two new enzymatic activities in the de novo purine biosynthetic pathway of Escherichia coli.
Volume: 33
Issue: 8
Pages: 2269-78
Protein Domain
Type: Domain
Description: The novo purine biosynthesis proceeds by two divergent paths. In bacteria, yeasts, and plants, 5-aminoimidazole ribonucleotide (AIR) is converted to 4-carboxy-AIR (CAIR) by two enzymes: N5-carboxy-AIR (N5-CAIR) synthetase (PurK) and N5-CAIR mutase (class I PurE). In animals, the conversion of AIR to CAIR requires a single enzyme, AIR carboxylase (class II PurE) []. Class I and class II PurEs are mechanistically related but bind different substrates. In yeast and plants PurE is found in PurK-class I PurE fusion proteins, known as ADE2 [, ], while animal class II PurEs are found in PurC-PurE fusion proteins, also known as ADE2 or PAICS []. This entry represents a class II PurE domain found in ADE2 fusion proteins from animals. It is also found in some bacteria, such as Treponema denticola. This spirochete dental pathogen lacks a purK gene and contains a class II purE gene [].
Protein Domain
Type: Domain
Description: The novo purine biosynthesis proceeds by two divergent paths. In bacteria, yeasts, and plants, 5-aminoimidazole ribonucleotide (AIR) is converted to 4-carboxy-AIR (CAIR) by two enzymes: N5-carboxy-AIR (N5-CAIR) synthetase (PurK) and N5-CAIR mutase (class I PurE). In animals, the conversion of AIR to CAIR requires a single enzyme, AIR carboxylase (class II PurE) []. Class I and class II PurEs are mechanistically related but bind different substrates. In yeast and plants PurE is found in PurK-class I PurE fusion proteins, known as ADE2 [, ], while animal class II PurEs are found in PurC-PurE fusion proteins, also known as ADE2 or PAICS []. This domain represents the class I PurE which is a N5-carboxyaminoimidazole ribonucleotide mutase [].
Publication
First Author: Tranchimand S
Year: 2011
Journal: Biochemistry
Title: Treponema denticola PurE Is a bacterial AIR carboxylase.
Volume: 50
Issue: 21
Pages: 4623-37