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Search results 201 to 300 out of 4212 for C3

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Type Details Score
Publication
18787004 | J:153394
First Author: Morrison TE
Year: 2008
Journal: J Virol
Title: Complement receptor 3 promotes severe ross river virus-induced disease.
Volume: 82
Issue: 22
Pages: 11263-72
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Publication
27735945 | J:337854
First Author: Magliarelli HF
Year: 2016
Journal: Cell Death Dis
Title: Liver ubiquitome uncovers nutrient-stress-mediated trafficking and secretion of complement C3.
Volume: 7
Issue: 10
Pages: e2411
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Publication
9794381 | J:112151
First Author: Qin D
Year: 1998
Journal: J Immunol
Title: Evidence for an important interaction between a complement-derived CD21 ligand on follicular dendritic cells and CD21 on B cells in the initiation of IgG responses.
Volume: 161
Issue: 9
Pages: 4549-54
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Publication
22721768 | J:187183
First Author: Berg A
Year: 2012
Journal: Exp Neurol
Title: Reduced removal of synaptic terminals from axotomized spinal motoneurons in the absence of complement C3.
Volume: 237
Issue: 1
Pages: 8-17
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Publication
17379312 | J:123562
First Author: Twohig J
Year: 2007
Journal: Mol Immunol
Title: Defective B cell ontogeny and immune response in human complement receptor 2 (CR2, CD21) transgenic mice is partially recovered in the absence of C3.
Volume: 44
Issue: 13
Pages: 3434-44
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Publication
9461092 | J:47055
First Author: Quigg RJ
Year: 1998
Journal: Kidney Int
Title: Immune complex glomerulonephritis in C4- and C3-deficient mice.
Volume: 53
Issue: 2
Pages: 320-30
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Publication
14500686 | J:85645
First Author: Tüzün E
Year: 2003
Journal: J Immunol
Title: Genetic evidence for involvement of classical complement pathway in induction of experimental autoimmune myasthenia gravis.
Volume: 171
Issue: 7
Pages: 3847-54
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Publication
9829481 | J:77011
First Author: Hébert MJ
Year: 1998
Journal: Nephrol Dial Transplant
Title: Acute nephrotoxic serum nephritis in complement knockout mice: relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria.
Volume: 13
Issue: 11
Pages: 2799-803
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Publication
28887040 | J:253995
First Author: Kim YJ
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Roles of antibodies to influenza A virus hemagglutinin, neuraminidase, and M2e in conferring cross protection.
Volume: 493
Issue: 1
Pages: 393-398
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Publication
8976192 | J:78296
First Author: Sylvestre D
Year: 1996
Journal: J Exp Med
Title: Immunoglobulin G-mediated inflammatory responses develop normally in complement-deficient mice.
Volume: 184
Issue: 6
Pages: 2385-92
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Protein
P01027
Organism: Mus musculus/domesticus
Length: 1663  
Fragment?: false
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Publication
26822321 | J:315895
 
First Author: Wu F
Year: 2016
Journal: J Neuroinflammation
Title: Complement component C3a plays a critical role in endothelial activation and leukocyte recruitment into the brain.
Volume: 13
Pages: 23
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Publication
22019898 | J:180268
First Author: Zhang J
Year: 2011
Journal: Am J Pathol
Title: The protective role of CD59 and pathogenic role of complement in hepatic ischemia and reperfusion injury.
Volume: 179
Issue: 6
Pages: 2876-84
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Publication
9409643 | J:44715
First Author: Sheerin NS
Year: 1997
Journal: Clin Exp Immunol
Title: Protection against anti-glomerular basement membrane (GBM)-mediated nephritis in C3- and C4-deficient mice.
Volume: 110
Issue: 3
Pages: 403-9
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Publication
31209071 | J:280638
First Author: Silverman SM
Year: 2019
Journal: J Exp Med
Title: C3- and CR3-dependent microglial clearance protects photoreceptors in retinitis pigmentosa.
Volume: 216
Issue: 8
Pages: 1925-1943
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Publication
10066708 | J:78613
First Author: Williams JP
Year: 1999
Journal: J Appl Physiol (1985)
Title: Intestinal reperfusion injury is mediated by IgM and complement.
Volume: 86
Issue: 3
Pages: 938-42
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Publication
28710441 | J:253722
First Author: Zhang L
Year: 2017
Journal: Sci Rep
Title: IgG3-antigen complexes are deposited on follicular dendritic cells in the presence of C1q and C3.
Volume: 7
Issue: 1
Pages: 5400
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Publication
18083105 | J:137589
First Author: Stevens B
Year: 2007
Journal: Cell
Title: The classical complement cascade mediates CNS synapse elimination.
Volume: 131
Issue: 6
Pages: 1164-78
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Publication
33897891 | J:320802
First Author: Ren J
Year: 2021
Journal: Theranostics
Title: Crosstalk between coagulation and complement activation promotes cardiac dysfunction in arrhythmogenic right ventricular cardiomyopathy.
Volume: 11
Issue: 12
Pages: 5939-5954
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Publication
37234916 | J:336575
 
First Author: Veremeyko T
Year: 2023
Journal: Front Cell Neurosci
Title: Complement C4-deficient mice have a high mortality rate during PTZ-induced epileptic seizures, which correlates with cognitive problems and the deficiency in the expression of Egr1 and other immediate early genes.
Volume: 17
Pages: 1170031
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Publication
29450541 | J:343010
First Author: Crowley MA
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Induction of Ocular Complement Activation by Inflammatory Stimuli and Intraocular Inhibition of Complement Factor D in Animal Models.
Volume: 59
Issue: 2
Pages: 940-951
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Publication
9467654 | J:45857
First Author: Pekna M
Year: 1998
Journal: Scand J Immunol
Title: Targeted disruption of the murine gene coding for the third complement component (C3).
Volume: 47
Issue: 1
Pages: 25-9
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Publication
17586095 | J:123553
First Author: Bykov I
Year: 2007
Journal: Clin Immunol
Title: Effect of chronic ethanol consumption on the expression of complement components and acute-phase proteins in liver.
Volume: 124
Issue: 2
Pages: 213-20
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Publication
20511542 | J:164531
First Author: Seregin SS
Year: 2010
Journal: Blood
Title: Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo.
Volume: 116
Issue: 10
Pages: 1669-77
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Publication
23824734 | J:203459
First Author: Gao X
Year: 2013
Journal: PLoS One
Title: Resistance to Streptozotocin-Induced Autoimmune Diabetes in Absence of Complement C3: Myeloid-Derived Suppressor Cells Play a Role.
Volume: 8
Issue: 6
Pages: e66334
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Publication
16982921 | J:139307
First Author: Koch CA
Year: 2006
Journal: J Immunol
Title: Complement-dependent control of teratoma formation by embryonic stem cells.
Volume: 177
Issue: 7
Pages: 4803-9
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Publication
36973281 | J:334938
First Author: Hu S
Year: 2023
Journal: Nat Commun
Title: Helicobacter pylori initiates successful gastric colonization by utilizing L-lactate to promote complement resistance.
Volume: 14
Issue: 1
Pages: 1695
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Publication
17330096 | J:121386
First Author: Wysoczynski M
Year: 2007
Journal: Leukemia
Title: Cleavage fragments of the third complement component (C3) enhance stromal derived factor-1 (SDF-1)-mediated platelet production during reactive postbleeding thrombocytosis.
Volume: 21
Issue: 5
Pages: 973-82
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Publication
10447759 | J:56335
First Author: Sheerin NS
Year: 1999
Journal: Immunology
Title: Altered distribution of intraglomerular immune complexes in C3-deficient mice.
Volume: 97
Issue: 3
Pages: 393-9
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Publication
18483395 | J:138442
First Author: Hod EA
Year: 2008
Journal: Blood
Title: Cytokine storm in a mouse model of IgG-mediated hemolytic transfusion reactions.
Volume: 112
Issue: 3
Pages: 891-4
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Publication
24948809 | J:317964
First Author: Bodea LG
Year: 2014
Journal: J Neurosci
Title: Neurodegeneration by activation of the microglial complement-phagosome pathway.
Volume: 34
Issue: 25
Pages: 8546-56
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Publication
21763674 | J:179950
First Author: Zhao L
Year: 2011
Journal: Am J Pathol
Title: Minocycline attenuates photoreceptor degeneration in a mouse model of subretinal hemorrhage microglial: inhibition as a potential therapeutic strategy.
Volume: 179
Issue: 3
Pages: 1265-77
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Publication
25308956 | J:230319
First Author: Baśkiewicz-Hałasa M
Year: 2015
Journal: Exp Hematol
Title: Mixed chimerism and transplant tolerance are not effectively induced in C3a-deficient mice.
Volume: 43
Issue: 1
Pages: 14-22
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Publication
27081859 | J:336571
First Author: Tan GS
Year: 2016
Journal: PLoS Pathog
Title: Broadly-Reactive Neutralizing and Non-neutralizing Antibodies Directed against the H7 Influenza Virus Hemagglutinin Reveal Divergent Mechanisms of Protection.
Volume: 12
Issue: 4
Pages: e1005578
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Publication
22966167 | J:191420
First Author: Li Y
Year: 2012
Journal: Blood
Title: Mesenchymal stem cells are injured by complement after their contact with serum.
Volume: 120
Issue: 17
Pages: 3436-43
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Publication
23511127 | J:200120
First Author: Borkowska S
Year: 2013
Journal: Leukemia
Title: Mobilization studies in C3-deficient mice unravel the involvement of a novel crosstalk between the coagulation and complement cascades in mobilization of hematopoietic stem/progenitor cells.
Volume: 27
Issue: 9
Pages: 1928-30
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Publication
18779337 | J:142540
First Author: Kim SH
Year: 2008
Journal: Infect Immun
Title: Recruitment of Rab27a to phagosomes controls microbial antigen cross-presentation by dendritic cells.
Volume: 76
Issue: 11
Pages: 5373-80
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Publication
17196951 | J:119533
First Author: Anderson DR
Year: 2007
Journal: Cardiovasc Res
Title: The role of complement in the adherence of microbubbles to dysfunctional arterial endothelium and atherosclerotic plaque.
Volume: 73
Issue: 3
Pages: 597-606
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Publication
24337750 | J:207322
First Author: Ito K
Year: 2014
Journal: J Immunol
Title: Lack of galactosylation enhances the pathogenic activity of IgG1 but Not IgG2a anti-erythrocyte autoantibodies.
Volume: 192
Issue: 2
Pages: 581-8
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Publication
27688803 | J:238926
First Author: Liu J
Year: 2016
Journal: Blood
Title: Antigen modulation as a potential mechanism of anti-KEL immunoprophylaxis in mice.
Volume: 128
Issue: 26
Pages: 3159-3168
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Publication
16299314 | J:104305
First Author: Takahashi K
Year: 2005
Journal: Infect Immun
Title: Relative roles of complement factor 3 and mannose-binding lectin in host defense against infection.
Volume: 73
Issue: 12
Pages: 8188-93
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Publication
28052876 | J:273995
First Author: Xavier S
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis.
Volume: 312
Issue: 3
Pages: F516-F532
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Publication
30429364 | J:272243
 
First Author: Mener A
Year: 2018
Journal: JCI Insight
Title: Complement serves as a switch between CD4+ T cell-independent and -dependent RBC antibody responses.
Volume: 3
Issue: 22
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Publication
28462915 | J:250385
 
First Author: Gorelik A
Year: 2017
Journal: Nat Commun
Title: Developmental activities of the complement pathway in migrating neurons.
Volume: 8
Pages: 15096
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Publication
23527240 | J:200181
First Author: Berg A
Year: 2013
Journal: PLoS One
Title: The extent of synaptic stripping of motoneurons after axotomy is not correlated to activation of surrounding glia or downregulation of postsynaptic adhesion molecules.
Volume: 8
Issue: 3
Pages: e59647
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Publication
33767691 | J:312673
 
First Author: Kohn M
Year: 2021
Journal: Front Immunol
Title: Complement and Chlamydia psittaci: Early Complement-Dependent Events Are Important for DC Migration and Protection During Mouse Lung Infection.
Volume: 12
Pages: 580594
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Publication
15284858 | J:336737
First Author: Ratajczak MZ
Year: 2004
Journal: Leukemia
Title: Transplantation studies in C3-deficient animals reveal a novel role of the third complement component (C3) in engraftment of bone marrow cells.
Volume: 18
Issue: 9
Pages: 1482-90
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Publication
16288049 | J:103401
First Author: Imai M
Year: 2005
Journal: Cancer Res
Title: Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer.
Volume: 65
Issue: 22
Pages: 10562-8
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Publication
12496386 | J:127041
First Author: Pozdnyakova O
Year: 2003
Journal: J Immunol
Title: Impaired antibody response to group B streptococcal type III capsular polysaccharide in C3- and complement receptor 2-deficient mice.
Volume: 170
Issue: 1
Pages: 84-90
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Publication
29581196 | J:264658
 
First Author: Riley SP
Year: 2018
Journal: Infect Immun
Title: Immunity against the Obligate Intracellular Bacterial Pathogen Rickettsia australis Requires a Functional Complement System.
Volume: 86
Issue: 6
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Publication
11801636 | J:127292
First Author: Einav S
Year: 2002
Journal: J Immunol
Title: Complement C4 is protective for lupus disease independent of C3.
Volume: 168
Issue: 3
Pages: 1036-41
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Publication
26873964 | J:232936
First Author: Yamamoto T
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia-reperfusion.
Volume: 310
Issue: 8
Pages: H1003-14
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Publication
23074214 | J:214214
First Author: Yu M
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: A novel role of complement in retinal degeneration.
Volume: 53
Issue: 12
Pages: 7684-92
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Publication
34536564 | J:341658
First Author: Li HY
Year: 2022
Journal: Cell Mol Gastroenterol Hepatol
Title: C-Reactive Protein Protects Against Acetaminophen-Induced Liver Injury by Preventing Complement Overactivation.
Volume: 13
Issue: 1
Pages: 289-307
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Publication
32866962 | J:300323
First Author: Zhang J
Year: 2020
Journal: Nature
Title: Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.
Volume: 588
Issue: 7838
Pages: 459-465
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Publication
34707103 | J:312392
First Author: Zheng Z
Year: 2021
Journal: Nat Commun
Title: Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3.
Volume: 12
Issue: 1
Pages: 6202
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Publication
17363917 | J:121549
First Author: Møller-Kristensen M
Year: 2007
Journal: J Invest Dermatol
Title: Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice.
Volume: 127
Issue: 6
Pages: 1524-31
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Publication
17947689 | J:152995
First Author: Zabel MD
Year: 2007
Journal: J Immunol
Title: Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.
Volume: 179
Issue: 9
Pages: 6144-52
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Publication
17681821 | J:124348
First Author: Green RS
Year: 2007
Journal: Immunity
Title: Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis.
Volume: 27
Issue: 2
Pages: 308-20
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Publication
28057640 | J:240426
First Author: Ueda Y
Year: 2017
Journal: Blood
Title: Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation.
Volume: 129
Issue: 9
Pages: 1184-1196
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Publication
16778201 | J:110103
First Author: Rozanov DV
Year: 2006
Journal: Cancer Res
Title: Interference with the complement system by tumor cell membrane type-1 matrix metalloproteinase plays a significant role in promoting metastasis in mice.
Volume: 66
Issue: 12
Pages: 6258-63
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Publication
9521809 | J:46795
First Author: Zelko I
Year: 1998
Journal: Arch Biochem Biophys
Title: Molecular cloning and characterization of a novel nuclear protein kinase in mice.
Volume: 352
Issue: 1
Pages: 31-6
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Publication
24667943 | J:216036
First Author: Borkowska S
Year: 2014
Journal: Leukemia
Title: Novel evidence that crosstalk between the complement, coagulation and fibrinolysis proteolytic cascades is involved in mobilization of hematopoietic stem/progenitor cells (HSPCs).
Volume: 28
Issue: 11
Pages: 2148-54
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Publication
10477568 | J:57602
First Author: Yan J
Year: 1999
Journal: J Immunol
Title: Beta-glucan, a "specific" biologic response modifier that uses antibodies to target tumors for cytotoxic recognition by leukocyte complement receptor type 3 (CD11b/CD18).
Volume: 163
Issue: 6
Pages: 3045-52
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Publication
17383432 | J:128218
First Author: Pritchard MT
Year: 2007
Journal: Gastroenterology
Title: Differential contributions of C3, C5, and decay-accelerating factor to ethanol-induced fatty liver in mice.
Volume: 132
Issue: 3
Pages: 1117-1126
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Publication
1378280 | J:1024
First Author: Holers VM
Year: 1992
Journal: Immunol Today
Title: The evolution of mouse and human complement C3-binding proteins: divergence of form but conservation of function.
Volume: 13
Issue: 6
Pages: 231-6
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Publication
32717081 | J:294941
 
First Author: Angeletti A
Year: 2020
Journal: J Exp Med
Title: Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis.
Volume: 217
Issue: 9
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Publication
31732528 | J:282189
First Author: Kulik L
Year: 2019
Journal: J Immunol
Title: Targeting the Immune Complex-Bound Complement C3d Ligand as a Novel Therapy for Lupus.
Volume: 203
Issue: 12
Pages: 3136-3147
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Publication
11441111 | J:120524
First Author: Baumann U
Year: 2001
Journal: J Immunol
Title: Distinct tissue site-specific requirements of mast cells and complement components C3/C5a receptor in IgG immune complex-induced injury of skin and lung.
Volume: 167
Issue: 2
Pages: 1022-7
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Publication
23733878 | J:205353
First Author: Donius LR
Year: 2013
Journal: J Immunol
Title: Optimal germinal center B cell activation and T-dependent antibody responses require expression of the mouse complement receptor Cr1.
Volume: 191
Issue: 1
Pages: 434-47
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Publication
36709213 | J:336253
First Author: Seifert L
Year: 2023
Journal: Nat Commun
Title: The classical pathway triggers pathogenic complement activation in membranous nephropathy.
Volume: 14
Issue: 1
Pages: 473
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Publication
9382884 | J:44403
First Author: Tang T
Year: 1997
Journal: J Exp Med
Title: A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis.
Volume: 186
Issue: 11
Pages: 1853-63
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Publication
16615889 | J:115872
First Author: Kang YS
Year: 2006
Journal: Cell
Title: A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q.
Volume: 125
Issue: 1
Pages: 47-58
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Publication
34417332 | J:336669
First Author: Peterson SL
Year: 2021
Journal: J Neurosci
Title: Retinal Ganglion Cell Axon Regeneration Requires Complement and Myeloid Cell Activity within the Optic Nerve.
Volume: 41
Issue: 41
Pages: 8508-8531
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Publication
15383609 | J:93718
First Author: Moll T
Year: 2004
Journal: J Immunol
Title: A critical role for Fc gamma RIIB in the induction of rheumatoid factors.
Volume: 173
Issue: 7
Pages: 4724-8
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Publication
17785849 | J:152026
First Author: Banda NK
Year: 2007
Journal: J Immunol
Title: Pathogenic complement activation in collagen antibody-induced arthritis in mice requires amplification by the alternative pathway.
Volume: 179
Issue: 6
Pages: 4101-9
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Publication
17675237 | J:125347
First Author: Giacomin PR
Year: 2008
Journal: Mol Immunol
Title: The role of complement in innate, adaptive and eosinophil-dependent immunity to the nematode Nippostrongylus brasiliensis.
Volume: 45
Issue: 2
Pages: 446-55
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Publication
16304047 | J:129369
First Author: Zhou W
Year: 2006
Journal: Blood
Title: Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells.
Volume: 107
Issue: 6
Pages: 2461-9
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Publication
31723045 | J:290773
First Author: Liu G
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: CRIg plays an essential role in intravascular clearance of bloodborne parasites by interacting with complement.
Volume: 116
Issue: 48
Pages: 24214-24220
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Publication
11544305 | J:118767
First Author: Hasegawa M
Year: 2001
Journal: J Immunol
Title: CD19 can regulate B lymphocyte signal transduction independent of complement activation.
Volume: 167
Issue: 6
Pages: 3190-200
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Publication
34249009 | J:314457
 
First Author: Escamilla-Rivera V
Year: 2021
Journal: Front Immunol
Title: Complement Plays a Critical Role in Inflammation-Induced Immunoprophylaxis Failure in Mice.
Volume: 12
Pages: 704072
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Publication
9367154 | J:44240
First Author: Prodeus AP
Year: 1997
Journal: Nature
Title: Impaired mast cell-dependent natural immunity in complement C3-deficient mice.
Volume: 390
Issue: 6656
Pages: 172-5
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Publication
21652682 | J:174858
First Author: Fang C
Year: 2011
Journal: Blood
Title: Decay-accelerating factor regulates T-cell immunity in the context of inflammation by influencing costimulatory molecule expression on antigen-presenting cells.
Volume: 118
Issue: 4
Pages: 1008-14
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Component
Component
Name: Complement C3 beta chain
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Component
Component
Name: Complement C3 alpha chain
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Strain
MGI:7433249 | C57BL/6 x C3
Attribute String: Not specified
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HT Sample
GSM1401
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal week 10-24
Stage: 28
Structure . Name: brain
Notes: wild type voxel C3
Curation Status: Curated
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Publication
29109438 | J:255926
First Author: Li J
Year: 2017
Journal: Nat Commun
Title: VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism.
Volume: 8
Issue: 1
Pages: 1322
•
•
•
•
•
Publication
32273396 | J:288328
 
First Author: Graham LC
Year: 2020
Journal: eNeuro
Title: Deficiency of Complement Component C1Q Prevents Cerebrovascular Damage and White Matter Loss in a Mouse Model of Chronic Obesity.
Volume: 7
Issue: 3
•
•
•
•
•
Publication
17709533 | J:151828
First Author: Fang C
Year: 2007
Journal: J Immunol
Title: Complement-dependent enhancement of CD8+ T cell immunity to lymphocytic choriomeningitis virus infection in decay-accelerating factor-deficient mice.
Volume: 179
Issue: 5
Pages: 3178-86
•
•
•
•
•
Publication
19414754 | J:148245
First Author: Chen Y
Year: 2009
Journal: J Immunol
Title: IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells.
Volume: 182
Issue: 10
Pages: 6031-43
•
•
•
•
•
Publication
15710649 | J:96689
First Author: Liu J
Year: 2005
Journal: J Exp Med
Title: The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo.
Volume: 201
Issue: 4
Pages: 567-77
•
•
•
•
•
Publication
35143312 | J:323813
First Author: Schriek P
Year: 2022
Journal: Science
Title: Marginal zone B cells acquire dendritic cell functions by trogocytosis.
Volume: 375
Issue: 6581
Pages: eabf7470
•
•
•
•
•
Publication
38280374 | J:345952
First Author: Wu M
Year: 2024
Journal: Cell
Title: Gut complement induced by the microbiota combats pathogens and spares commensals.
Volume: 187
Issue: 4
Pages: 897-913.e18
•
•
•
•
•
Allele
Tg(Rr404-lacZ)#Sopa | MGI:7449026
Name: transgene insertion, Soochul Park
Allele Type: Transgenic
Attribute String: Reporter
•
•
•
•
•
Publication
31578522 | J:283349
First Author: Aykut B
Year: 2019
Journal: Nature
Title: The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL.
Volume: 574
Issue: 7777
Pages: 264-267
•
•
•
•
•
Publication
21148255 | J:185883
First Author: de Jorge EG
Year: 2011
Journal: J Am Soc Nephrol
Title: The development of atypical hemolytic uremic syndrome depends on complement C5.
Volume: 22
Issue: 1
Pages: 137-45
•
•
•
•
•
Publication
23946404 | J:200899
First Author: Stephan AH
Year: 2013
Journal: J Neurosci
Title: A dramatic increase of C1q protein in the CNS during normal aging.
Volume: 33
Issue: 33
Pages: 13460-74
•
•
•
•
•
Publication
16951374 | J:138043
First Author: Turnberg D
Year: 2006
Journal: J Immunol
Title: Complement activation contributes to both glomerular and tubulointerstitial damage in adriamycin nephropathy in mice.
Volume: 177
Issue: 6
Pages: 4094-102
•
•
•
•
•
Publication
25127469 | J:223144
First Author: Kataoka H
Year: 2014
Journal: PLoS One
Title: Evaluation of the contribution of multiple DAMPs and DAMP receptors in cell death-induced sterile inflammatory responses.
Volume: 9
Issue: 8
Pages: e104741
•
•
•
•
•




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