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Search results 2901 to 3000 out of 3931 for Mtor

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Type Details Score
Publication
20543991 | J:161591
First Author: Siuta MA
Year: 2010
Journal: PLoS Biol
Title: Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice.
Volume: 8
Issue: 6
Pages: e1000393
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33027655 | J:304671
First Author: Hsiao WY
Year: 2020
Journal: Cell Rep
Title: The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development.
Volume: 33
Issue: 1
Pages: 108223
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Publication
31401286 | J:293209
First Author: Ding X
Year: 2020
Journal: J Allergy Clin Immunol
Title: Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation.
Volume: 145
Issue: 1
Pages: 283-300.e8
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Publication
32905798 | J:296626
First Author: Kim CS
Year: 2020
Journal: Cell Metab
Title: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle.
Volume: 32
Issue: 4
Pages: 629-642.e8
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28694518 | J:270960
First Author: Hu T
Year: 2017
Journal: Sci Rep
Title: PDK1 plays a vital role on hematopoietic stem cell function.
Volume: 7
Issue: 1
Pages: 4943
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Publication
34855620 | J:325153
 
First Author: Bhat N
Year: 2022
Journal: J Clin Invest
Title: Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice.
Volume: 132
Issue: 3
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27225119 | J:235750
First Author: Zhou F
Year: 2016
Journal: Nature
Title: Tracing haematopoietic stem cell formation at single-cell resolution.
Volume: 533
Issue: 7604
Pages: 487-92
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Publication
26459601 | J:237592
First Author: Zou Z
Year: 2015
Journal: J Cell Biol
Title: mTORC2 promotes cell survival through c-Myc-dependent up-regulation of E2F1.
Volume: 211
Issue: 1
Pages: 105-22
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Publication
18426911 | J:137298
First Author: Hagan GN
Year: 2008
Journal: Mol Cell Biol
Title: A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes.
Volume: 28
Issue: 13
Pages: 4215-26
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Publication
23563706 | J:198532
First Author: Meng ZX
Year: 2013
Journal: Nat Med
Title: Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation.
Volume: 19
Issue: 5
Pages: 640-5
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Publication
29164996 | J:257335
   
First Author: Mishra SK
Year: 2018
Journal: Autophagy
Title: CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation.
Pages: 1-18
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17273556 | J:118038
First Author: Le Bacquer O
Year: 2007
Journal: J Clin Invest
Title: Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.
Volume: 117
Issue: 2
Pages: 387-96
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16710422 | J:109025
First Author: Kim S
Year: 2006
Journal: Nature
Title: A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth.
Volume: 441
Issue: 7091
Pages: 362-5
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18487439 | J:138207
First Author: Essop MF
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice.
Volume: 295
Issue: 1
Pages: H256-65
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Publication
27951586 | J:240431
     
First Author: Karki R
Year: 2016
Journal: Nature
Title: NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer.
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18974783 | J:143922
First Author: Chen J
Year: 2008
Journal: PLoS One
Title: Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.
Volume: 3
Issue: 10
Pages: e3581
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22709692 | J:189078
First Author: Baba M
Year: 2012
Journal: Blood
Title: The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.
Volume: 120
Issue: 6
Pages: 1254-61
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29897930 | J:262829
First Author: Centini R
Year: 2018
Journal: PLoS One
Title: Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation.
Volume: 13
Issue: 6
Pages: e0197973
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27378698 | J:237861
First Author: Magalhaes J
Year: 2016
Journal: Hum Mol Genet
Title: Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease.
Volume: 25
Issue: 16
Pages: 3432-3445
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15705789 | J:98472
First Author: Hammerman PS
Year: 2005
Journal: Blood
Title: Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival.
Volume: 105
Issue: 11
Pages: 4477-83
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17476689 | J:153319
First Author: Bohensky J
Year: 2007
Journal: J Cell Physiol
Title: PIM-2 is an independent regulator of chondrocyte survival and autophagy in the epiphyseal growth plate.
Volume: 213
Issue: 1
Pages: 246-51
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Publication
23695157 | J:201107
First Author: Al-Qusairi L
Year: 2013
Journal: FASEB J
Title: Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways.
Volume: 27
Issue: 8
Pages: 3384-94
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18347057 | J:136089
First Author: Bayascas JR
Year: 2008
Journal: Mol Cell Biol
Title: Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Volume: 28
Issue: 10
Pages: 3258-72
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25139996 | J:216403
First Author: Nikonova AS
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Nedd9 restrains renal cystogenesis in Pkd1-/- mice.
Volume: 111
Issue: 35
Pages: 12859-64
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29288408 | J:272348
First Author: Wu W
Year: 2018
Journal: J Physiol Biochem
Title: Muscle-specific deletion of Prkaa1 enhances skeletal muscle lipid accumulation in mice fed a high-fat diet.
Volume: 74
Issue: 2
Pages: 195-205
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24064341 | J:205003
First Author: Auffret J
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Defective prolactin signaling impairs pancreatic β-cell development during the perinatal period.
Volume: 305
Issue: 10
Pages: E1309-18
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35971771 | J:328707
   
First Author: Romero-Becerra R
Year: 2022
Journal: Elife
Title: MKK6 deficiency promotes cardiac dysfunction through MKK3-p38γ/δ-mTOR hyperactivation.
Volume: 11
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27197194 | J:234851
First Author: Beziaud L
Year: 2016
Journal: Cancer Res
Title: Rapalogs Efficacy Relies on the Modulation of Antitumor T-cell Immunity.
Volume: 76
Issue: 14
Pages: 4100-12
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22412198 | J:184070
First Author: Pan H
Year: 2012
Journal: J Immunol
Title: The role of tuberous sclerosis complex 1 in regulating innate immunity.
Volume: 188
Issue: 8
Pages: 3658-66
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36478736 | J:331988
 
First Author: Istiaq A
Year: 2022
Journal: Front Cell Dev Biol
Title: Tsukushi proteoglycan maintains RNA splicing and developmental signaling network in GFAP-expressing subventricular zone neural stem/progenitor cells.
Volume: 10
Pages: 994588
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29938573 | J:302615
First Author: Yeo SK
Year: 2018
Journal: Autophagy
Title: Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer.
Volume: 14
Issue: 7
Pages: 1214-1225
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26271103 | J:226632
First Author: Demitrack ES
Year: 2015
Journal: EMBO J
Title: Notch signaling regulates gastric antral LGR5 stem cell function.
Volume: 34
Issue: 20
Pages: 2522-36
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Publication
34787081 | J:314954
   
First Author: Conde-Dusman MJ
Year: 2021
Journal: Elife
Title: Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly.
Volume: 10
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16166381 | J:100952
First Author: Ruvinsky I
Year: 2005
Journal: Genes Dev
Title: Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis.
Volume: 19
Issue: 18
Pages: 2199-211
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26283674 | J:293583
First Author: Volovelsky O
Year: 2016
Journal: J Am Soc Nephrol
Title: Phosphorylation of Ribosomal Protein S6 Mediates Mammalian Target of Rapamycin Complex 1-Induced Parathyroid Cell Proliferation in Secondary Hyperparathyroidism.
Volume: 27
Issue: 4
Pages: 1091-101
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19808022 | J:153660
First Author: Granot Z
Year: 2009
Journal: Cell Metab
Title: LKB1 regulates pancreatic beta cell size, polarity, and function.
Volume: 10
Issue: 4
Pages: 296-308
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37068088 | J:335072
First Author: Decourt C
Year: 2023
Journal: PLoS Biol
Title: The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems.
Volume: 21
Issue: 4
Pages: e3002044
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29643507 | J:261638
First Author: Liakath-Ali K
Year: 2018
Journal: Nature
Title: An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis.
Volume: 556
Issue: 7701
Pages: 376-380
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34571934 | J:311506
 
First Author: Peng Y
Year: 2021
Journal: Cells
Title: Substrate Reduction Therapy Reverses Mitochondrial, mTOR, and Autophagy Alterations in a Cell Model of Gaucher Disease.
Volume: 10
Issue: 9
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29717938 | J:280706
First Author: Kipp KR
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Comparison of folate-conjugated rapamycin versus unconjugated rapamycin in an orthologous mouse model of polycystic kidney disease.
Volume: 315
Issue: 2
Pages: F395-F405
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Publication
31167126 | J:283524
First Author: Yang L
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: CD74 knockout attenuates alcohol intake-induced cardiac dysfunction through AMPK-Skp2-mediated regulation of autophagy.
Volume: 1865
Issue: 9
Pages: 2368-2378
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25339759 | J:217151
First Author: Shibuya Y
Year: 2014
Journal: J Neurosci
Title: Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance.
Volume: 34
Issue: 43
Pages: 14484-501
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Publication
29501742 | J:273677
First Author: Li H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling.
Volume: 498
Issue: 1
Pages: 234-239
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Publication
22960314 | J:192478
 
First Author: Algarzae N
Year: 2012
Journal: Neuroscience
Title: Parkin prevents cortical atrophy and Aβ-induced alterations of brain metabolism: ¹³C NMR and magnetic resonance imaging studies in AD models.
Volume: 225
Pages: 22-34
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29083325 | J:250089
     
First Author: Kang HS
Year: 2017
Journal: J Clin Invest
Title: GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation.
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Publication
22662254 | J:187301
First Author: Esteves CL
Year: 2012
Journal: PLoS One
Title: Regulation of adipocyte 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) by CCAAT/enhancer-binding protein (C/EBP) β isoforms, LIP and LAP.
Volume: 7
Issue: 5
Pages: e37953
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24785297 | J:211065
First Author: Park H
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development.
Volume: 111
Issue: 19
Pages: 7066-71
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20072130 | J:162611
First Author: Janes MR
Year: 2010
Journal: Nat Med
Title: Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
Volume: 16
Issue: 2
Pages: 205-13
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34440840 | J:311075
 
First Author: Biasizzo M
Year: 2021
Journal: Cells
Title: Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice.
Volume: 10
Issue: 8
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22351927 | J:181685
First Author: Bakkar N
Year: 2012
Journal: J Cell Biol
Title: IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism.
Volume: 196
Issue: 4
Pages: 497-511
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32591410 | J:296309
First Author: Yamauchi Y
Year: 2020
Journal: Cancer Res
Title: Rb and p53 Execute Distinct Roles in the Development of Pancreatic Neuroendocrine Tumors.
Volume: 80
Issue: 17
Pages: 3620-3630
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27270670 | J:249539
First Author: Baj G
Year: 2016
Journal: J Cell Sci
Title: Signaling pathways controlling activity-dependent local translation of BDNF and their localization in dendritic arbors.
Volume: 129
Issue: 14
Pages: 2852-64
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16908864 | J:112917
First Author: Rossi F
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor.
Volume: 103
Issue: 34
Pages: 12843-8
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36125265 | J:330376
First Author: Riehle C
Year: 2022
Journal: Mol Cell Biol
Title: Insulin and Insulin-Like Growth Factor 1 Signaling Preserves Sarcomere Integrity in the Adult Heart.
Volume: 42
Issue: 10
Pages: e0016322
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30848941 | J:294073
First Author: Shi J
Year: 2019
Journal: FASEB J
Title: Disruption of both ROCK1 and ROCK2 genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging.
Volume: 33
Issue: 6
Pages: 7348-7362
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30622306 | J:295469
First Author: He J
Year: 2019
Journal: Cell Death Differ
Title: Stage-specific requirement of kinase PDK1 for NK cells development and activation.
Volume: 26
Issue: 10
Pages: 1918-1928
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31949292 | J:303637
First Author: Zhang SL
Year: 2020
Journal: Acta Pharmacol Sin
Title: Aggravated ulcerative colitis caused by intestinal Metrnl deficiency is associated with reduced autophagy in epithelial cells.
Volume: 41
Issue: 6
Pages: 763-770
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25304685 | J:219673
First Author: Kocher BA
Year: 2015
Journal: Mol Cancer Res
Title: DAPK3 suppresses acini morphogenesis and is required for mouse development.
Volume: 13
Issue: 2
Pages: 358-67
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23832089 | J:199992
First Author: Pajvani UB
Year: 2013
Journal: Nat Med
Title: Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability.
Volume: 19
Issue: 8
Pages: 1054-60
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34228176 | J:324585
First Author: Figueiredo M
Year: 2021
Journal: Pflugers Arch
Title: The (pro)renin receptor (ATP6ap2) facilitates receptor-mediated endocytosis and lysosomal function in the renal proximal tubule.
Volume: 473
Issue: 8
Pages: 1229-1246
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29374060 | J:262854
First Author: Zhang J
Year: 2018
Journal: J Biol Chem
Title: S-Glutathionylation of estrogen receptor α affects dendritic cell function.
Volume: 293
Issue: 12
Pages: 4366-4380
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11909972 | J:75780
First Author: Shioi T
Year: 2002
Journal: Mol Cell Biol
Title: Akt/protein kinase B promotes organ growth in transgenic mice.
Volume: 22
Issue: 8
Pages: 2799-809
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25535334 | J:224296
First Author: Wende AR
Year: 2015
Journal: Mol Cell Biol
Title: Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.
Volume: 35
Issue: 5
Pages: 831-46
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25094045 | J:220115
First Author: Arumugam A
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch.
Volume: 451
Issue: 3
Pages: 394-401
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34324436 | J:312839
 
First Author: Chen HR
Year: 2021
Journal: JCI Insight
Title: Creatine transporter deficiency impairs stress adaptation and brain energetics homeostasis.
Volume: 6
Issue: 17
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21805467 | J:179527
First Author: O'Brien TF
Year: 2011
Journal: Eur J Immunol
Title: Regulation of T-cell survival and mitochondrial homeostasis by TSC1.
Volume: 41
Issue: 11
Pages: 3361-70
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22993204 | J:190634
First Author: Zhao YG
Year: 2012
Journal: J Immunol
Title: Dihydroartemisinin ameliorates inflammatory disease by its reciprocal effects on Th and regulatory T cell function via modulating the mammalian target of rapamycin pathway.
Volume: 189
Issue: 9
Pages: 4417-25
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25607841 | J:217651
First Author: Zhang Y
Year: 2015
Journal: J Clin Invest
Title: GP96 is a GARP chaperone and controls regulatory T cell functions.
Volume: 125
Issue: 2
Pages: 859-69
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24614103 | J:209612
First Author: Wu J
Year: 2014
Journal: J Clin Invest
Title: iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.
Volume: 124
Issue: 4
Pages: 1685-98
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26420838 | J:226843
First Author: Dasgupta N
Year: 2015
Journal: Hum Mol Genet
Title: Neuronopathic Gaucher disease: dysregulated mRNAs and miRNAs in brain pathogenesis and effects of pharmacologic chaperone treatment in a mouse model.
Volume: 24
Issue: 24
Pages: 7031-48
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33239450 | J:307110
First Author: Bozadjieva Kramer N
Year: 2021
Journal: Diabetes
Title: Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia.
Volume: 70
Issue: 2
Pages: 477-491
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15833854 | J:97830
First Author: Wislez M
Year: 2005
Journal: Cancer Res
Title: Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras.
Volume: 65
Issue: 8
Pages: 3226-35
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19330036 | J:147455
First Author: Granville CA
Year: 2009
Journal: PLoS One
Title: A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis.
Volume: 4
Issue: 3
Pages: e5061
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18316617 | J:132860
First Author: Hegedus B
Year: 2008
Journal: Cancer Res
Title: Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma.
Volume: 68
Issue: 5
Pages: 1520-8
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21242979 | J:170765
First Author: Hollander MC
Year: 2011
Journal: Oncogene
Title: Akt1 deletion prevents lung tumorigenesis by mutant K-ras.
Volume: 30
Issue: 15
Pages: 1812-21
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23454899 | J:200122
First Author: Molina-Arcas M
Year: 2013
Journal: Cancer Discov
Title: Coordinate direct input of both KRAS and IGF1 receptor to activation of PI3 kinase in KRAS-mutant lung cancer.
Volume: 3
Issue: 5
Pages: 548-63
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31714935 | J:282286
First Author: Takai S
Year: 2019
Journal: PLoS One
Title: Effects of insulin signaling on mouse taste cell proliferation.
Volume: 14
Issue: 11
Pages: e0225190
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34054815 | J:314529
 
First Author: McKell MC
Year: 2021
Journal: Front Immunol
Title: Promotion of Anti-Tuberculosis Macrophage Activity by L-Arginine in the Absence of Nitric Oxide.
Volume: 12
Pages: 653571
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32707827 | J:294999
 
First Author: Parigiani MA
Year: 2020
Journal: Cancers (Basel)
Title: Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression.
Volume: 12
Issue: 8
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34087956 | J:310503
First Author: Shin HJ
Year: 2021
Journal: Aging Cell
Title: Nucleotide-binding domain and leucine-rich-repeat-containing protein X1 deficiency induces nicotinamide adenine dinucleotide decline, mechanistic target of rapamycin activation, and cellular senescence and accelerates aging lung-like changes.
Volume: 20
Issue: 7
Pages: e13410
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26019175 | J:223927
First Author: Iwayama T
Year: 2015
Journal: Genes Dev
Title: PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity.
Volume: 29
Issue: 11
Pages: 1106-19
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35021092 | J:327196
First Author: Zhang Z
Year: 2022
Journal: Cell Rep
Title: CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling.
Volume: 38
Issue: 2
Pages: 110009
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34547769 | J:323302
First Author: Abbonante V
Year: 2021
Journal: Blood Adv
Title: Ablation of collagen VI leads to the release of platelets with altered function.
Volume: 5
Issue: 23
Pages: 5150-5163
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23698118 | J:200847
First Author: Watts BA 3rd
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Lumen LPS inhibits HCO3(-) absorption in the medullary thick ascending limb through TLR4-PI3K-Akt-mTOR-dependent inhibition of basolateral Na+/H+ exchange.
Volume: 305
Issue: 4
Pages: F451-62
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Publication
35626041 | J:333406
 
First Author: Kondylis V
Year: 2022
Journal: Cancers (Basel)
Title: p62 Promotes Survival and Hepatocarcinogenesis in Mice with Liver-Specific NEMO Ablation.
Volume: 14
Issue: 10
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