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Search results 101 to 200 out of 346 for Ryr2

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Type Details Score
Publication
22406107 | J:186219
First Author: Liu D
Year: 2012
Journal: Biochem Pharmacol
Title: The inhibitory glutathione transferase M2-2 binding site is located in divergent region 3 of the cardiac ryanodine receptor.
Volume: 83
Issue: 11
Pages: 1523-9
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25605235 | J:221370
First Author: Mi T
Year: 2015
Journal: Biochem J
Title: Role of Cys³⁶⁰² in the function and regulation of the cardiac ryanodine receptor.
Volume: 467
Issue: 1
Pages: 177-90
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Publication
29150444 | J:256073
First Author: Yang J
Year: 2018
Journal: J Biol Chem
Title: Toll-like receptor 4-induced ryanodine receptor 2 oxidation and sarcoplasmic reticulum Ca2+ leakage promote cardiac contractile dysfunction in sepsis.
Volume: 293
Issue: 3
Pages: 794-807
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Publication
33790404 | J:305394
First Author: Nakamura Y
Year: 2021
Journal: Sci Rep
Title: Enhancing calmodulin binding to ryanodine receptor is crucial to limit neuronal cell loss in Alzheimer disease.
Volume: 11
Issue: 1
Pages: 7289
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Publication
21768539 | J:186291
First Author: Suetomi T
Year: 2011
Journal: Circulation
Title: Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca²⁺release leading to catecholaminergic polymorphic ventricular tachycardia.
Volume: 124
Issue: 6
Pages: 682-94
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Publication
28620067 | J:267231
First Author: Bongianino R
Year: 2017
Journal: Circ Res
Title: Allele-Specific Silencing of Mutant mRNA Rescues Ultrastructural and Arrhythmic Phenotype in Mice Carriers of the R4496C Mutation in the Ryanodine Receptor Gene (RYR2).
Volume: 121
Issue: 5
Pages: 525-536
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Publication
36963751 | J:334734
 
First Author: Fujii S
Year: 2023
Journal: J Mol Cell Cardiol
Title: RyR2-targeting therapy prevents left ventricular remodeling and ventricular tachycardia in post-infarction heart failure.
Volume: 178
Pages: 36-50
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Publication
30541771 | J:319309
First Author: Potenza DM
Year: 2019
Journal: J Gen Physiol
Title: Phosphorylation of the ryanodine receptor 2 at serine 2030 is required for a complete β-adrenergic response.
Volume: 151
Issue: 2
Pages: 131-145
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Publication
23152493 | J:212870
First Author: Loaiza R
Year: 2013
Journal: Circ Res
Title: Heterogeneity of ryanodine receptor dysfunction in a mouse model of catecholaminergic polymorphic ventricular tachycardia.
Volume: 112
Issue: 2
Pages: 298-308
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Publication
24398018 | J:219309
First Author: Li N
Year: 2014
Journal: Circulation
Title: Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model.
Volume: 129
Issue: 12
Pages: 1276-1285
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Publication
20224043 | J:159451
First Author: Uchinoumi H
Year: 2010
Journal: Circ Res
Title: Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor.
Volume: 106
Issue: 8
Pages: 1413-24
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Publication
24805197 | J:219041
 
First Author: Zhang JZ
Year: 2014
Journal: J Mol Cell Cardiol
Title: The arrhythmogenic human HRC point mutation S96A leads to spontaneous Ca(2+) release due to an impaired ability to buffer store Ca(2+).
Volume: 74
Pages: 22-31
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Publication
17452324 | J:122995
First Author: Wang R
Year: 2007
Journal: J Biol Chem
Title: Localization of an NH(2)-terminal disease-causing mutation hot spot to the "clamp" region in the three-dimensional structure of the cardiac ryanodine receptor.
Volume: 282
Issue: 24
Pages: 17785-93
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Publication
26405799 | J:243328
First Author: Xiao Z
Year: 2015
Journal: PLoS One
Title: The H29D Mutation Does Not Enhance Cytosolic Ca2+ Activation of the Cardiac Ryanodine Receptor.
Volume: 10
Issue: 9
Pages: e0139058
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Publication
32580946 | J:299143
First Author: Baine S
Year: 2020
Journal: J Biol Chem
Title: Muscarinic-dependent phosphorylation of the cardiac ryanodine receptor by protein kinase G is mediated by PI3K-AKT-nNOS signaling.
Volume: 295
Issue: 33
Pages: 11720-11728
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Publication
31235574 | J:278236
First Author: Park SJ
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome.
Volume: 116
Issue: 28
Pages: 14154-14163
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26410369 | J:258492
First Author: Liu B
Year: 2015
Journal: Cardiovasc Res
Title: Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT.
Volume: 108
Issue: 2
Pages: 299-311
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Publication
31182474 | J:280019
 
First Author: Ma H
Year: 2019
Journal: eNeuro
Title: Ryanodine Receptor 2 Contributes to Impaired Protein Localization in Cyclic Nucleotide-Gated Channel Deficiency.
Volume: 6
Issue: 3
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24104877 | J:219543
First Author: Ho HT
Year: 2014
Journal: Cardiovasc Res
Title: Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides.
Volume: 101
Issue: 1
Pages: 165-74
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Publication
19120137 | J:145985
 
First Author: Jurkovicova D
Year: 2008
Journal: Ann N Y Acad Sci
Title: Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.
Volume: 1148
Pages: 421-7
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Publication
11159936 | J:67173
First Author: Tiso N
Year: 2001
Journal: Hum Mol Genet
Title: Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).
Volume: 10
Issue: 3
Pages: 189-94
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16204356 | J:104643
First Author: Takeda T
Year: 2005
Journal: FASEB J
Title: Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling.
Volume: 19
Issue: 14
Pages: 2069-71
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17404231 | J:120848
First Author: Anyatonwu GI
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2.
Volume: 104
Issue: 15
Pages: 6454-9
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24445321 | J:221099
First Author: Liu B
Year: 2014
Journal: J Physiol
Title: Genetic ablation of ryanodine receptor 2 phosphorylation at Ser-2808 aggravates Ca(2+)-dependent cardiomyopathy by exacerbating diastolic Ca2+ release.
Volume: 592
Issue: 9
Pages: 1957-73
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36672139 | J:336233
 
First Author: Deb A
Year: 2023
Journal: Cells
Title: Genetic Inhibition of Mitochondrial Permeability Transition Pore Exacerbates Ryanodine Receptor 2 Dysfunction in Arrhythmic Disease.
Volume: 12
Issue: 2
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26888649 | J:269208
 
First Author: Yuan Q
Year: 2016
Journal: Sci Rep
Title: Calstabin 2: An important regulator for learning and memory in mice.
Volume: 6
Pages: 21087
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21788490 | J:176005
First Author: Fauconnier J
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion.
Volume: 108
Issue: 32
Pages: 13258-63
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19603549 | J:152544
First Author: Chelu MG
Year: 2009
Journal: J Clin Invest
Title: Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.
Volume: 119
Issue: 7
Pages: 1940-51
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Publication
23454728 | J:202429
First Author: Kaya L
Year: 2013
Journal: Biochim Biophys Acta
Title: Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons.
Volume: 1833
Issue: 6
Pages: 1421-33
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29730765 | J:325842
First Author: Grillo MA
Year: 2019
Journal: Mol Neurobiol
Title: Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.
Volume: 56
Issue: 1
Pages: 525-534
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Publication
29037982 | J:256541
 
First Author: Lezcano N
Year: 2018
Journal: J Mol Cell Cardiol
Title: Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca2+ handling in cardiomyocytes.
Volume: 114
Pages: 1-9
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31805819 | J:302824
First Author: Zhou X
Year: 2020
Journal: Circ Res
Title: TRIC-A Channel Maintains Store Calcium Handling by Interacting With Type 2 Ryanodine Receptor in Cardiac Muscle.
Volume: 126
Issue: 4
Pages: 417-435
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30169578 | J:291512
First Author: Valverde CA
Year: 2019
Journal: Cardiovasc Res
Title: Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors.
Volume: 115
Issue: 3
Pages: 556-569
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9204703 | J:41094
First Author: Ponting C
Year: 1997
Journal: Trends Biochem Sci
Title: SPRY domains in ryanodine receptors (Ca(2+)-release channels).
Volume: 22
Issue: 6
Pages: 193-4
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19383796 | J:149895
First Author: Chopra N
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.
Volume: 106
Issue: 18
Pages: 7636-41
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18077344 | J:141533
First Author: Gonzalez DR
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Deficient ryanodine receptor S-nitrosylation increases sarcoplasmic reticulum calcium leak and arrhythmogenesis in cardiomyocytes.
Volume: 104
Issue: 51
Pages: 20612-7
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32173907 | J:302060
First Author: Yang F
Year: 2020
Journal: FASEB J
Title: Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling-induced cone degeneration in cyclic nucleotide-gated channel deficiency.
Volume: 34
Issue: 5
Pages: 6335-6350
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Publication
29986885 | J:270136
First Author: Sun B
Year: 2018
Journal: J Biol Chem
Title: The cardiac ryanodine receptor, but not sarcoplasmic reticulum Ca2+-ATPase, is a major determinant of Ca2+ alternans in intact mouse hearts.
Volume: 293
Issue: 35
Pages: 13650-13661
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32713021 | J:299886
First Author: Saadeh K
Year: 2020
Journal: Ann N Y Acad Sci
Title: Protein expression profiles in murine ventricles modeling catecholaminergic polymorphic ventricular tachycardia: effects of genotype and sex.
Volume: 1478
Issue: 1
Pages: 63-74
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Publication
17921453 | J:145811
First Author: Xiao J
Year: 2007
Journal: J Biol Chem
Title: Removal of FKBP12.6 does not alter the conductance and activation of the cardiac ryanodine receptor or the susceptibility to stress-induced ventricular arrhythmias.
Volume: 282
Issue: 48
Pages: 34828-38
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Publication
25193703 | J:319089
First Author: Yamakawa H
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Suppression of Rad leads to arrhythmogenesis via PKA-mediated phosphorylation of ryanodine receptor activity in the heart.
Volume: 452
Issue: 3
Pages: 701-7
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30181262 | J:266181
First Author: Pritchard HAT
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy.
Volume: 115
Issue: 41
Pages: E9745-E9752
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19578067 | J:172481
First Author: Zhang X
Year: 2009
Journal: Cardiovasc Res
Title: Dissociation of FKBP12.6 from ryanodine receptor type 2 is regulated by cyclic ADP-ribose but not beta-adrenergic stimulation in mouse cardiomyocytes.
Volume: 84
Issue: 2
Pages: 253-62
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23516528 | J:199919
First Author: Dixit SS
Year: 2013
Journal: PLoS One
Title: Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance.
Volume: 8
Issue: 3
Pages: e58655
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Publication
19549818 | J:150826
First Author: Liu QH
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.
Volume: 106
Issue: 27
Pages: 11418-23
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25193470 | J:218693
First Author: Wang W
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice.
Volume: 307
Issue: 9
Pages: H1317-26
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19011160 | J:160862
First Author: Liu QH
Year: 2009
Journal: Am J Respir Cell Mol Biol
Title: Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.
Volume: 40
Issue: 6
Pages: 663-71
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16481613 | J:107249
First Author: Huang F
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Analysis of calstabin2 (FKBP12.6)-ryanodine receptor interactions: rescue of heart failure by calstabin2 in mice.
Volume: 103
Issue: 9
Pages: 3456-61
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16844763 | J:112566
First Author: Stolk M
Year: 2006
Journal: J Leukoc Biol
Title: IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.
Volume: 80
Issue: 3
Pages: 651-8
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14592808 | J:87932
First Author: Wang YX
Year: 2004
Journal: Am J Physiol Cell Physiol
Title: FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.
Volume: 286
Issue: 3
Pages: C538-46
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24949568 | J:243767
 
First Author: Di Carlo MN
Year: 2014
Journal: J Mol Cell Cardiol
Title: CaMKII-dependent phosphorylation of cardiac ryanodine receptors regulates cell death in cardiac ischemia/reperfusion injury.
Volume: 74
Pages: 274-83
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22828895 | J:212640
First Author: Shan J
Year: 2012
Journal: Circ Res
Title: Calcium leak through ryanodine receptors leads to atrial fibrillation in 3 mouse models of catecholaminergic polymorphic ventricular tachycardia.
Volume: 111
Issue: 6
Pages: 708-17
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23992453 | J:203925
First Author: Tian X
Year: 2013
Journal: Biochem J
Title: Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release.
Volume: 455
Issue: 3
Pages: 367-75
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22798524 | J:212646
First Author: Carnicer R
Year: 2012
Journal: Circ Res
Title: Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation.
Volume: 111
Issue: 6
Pages: 718-27
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21421818 | J:170449
First Author: Yamaguchi N
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules.
Volume: 300
Issue: 6
Pages: H2187-95
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9124414 | J:38828
First Author: Marks AR
Year: 1997
Journal: Am J Physiol
Title: Intracellular calcium-release channels: regulators of cell life and death.
Volume: 272
Issue: 2 Pt 2
Pages: H597-605
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9628868 | J:48277
First Author: Takeshima H
Year: 1998
Journal: EMBO J
Title: Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2.
Volume: 17
Issue: 12
Pages: 3309-16
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35449169 | J:325606
First Author: Lu F
Year: 2022
Journal: Nat Commun
Title: CMYA5 establishes cardiac dyad architecture and positioning.
Volume: 13
Issue: 1
Pages: 2185
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37343080 | J:338141
First Author: Reyes Gaido OE
Year: 2023
Journal: Sci Transl Med
Title: An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor.
Volume: 15
Issue: 701
Pages: eabq7839
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Publication
31155924 | J:292478
First Author: Bezzerides VJ
Year: 2019
Journal: Circulation
Title: Gene Therapy for Catecholaminergic Polymorphic Ventricular Tachycardia by Inhibition of Ca2+/Calmodulin-Dependent Kinase II.
Volume: 140
Issue: 5
Pages: 405-419
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Publication
20621925 | J:186047
First Author: Zhang Y
Year: 2011
Journal: Cardiovasc Res
Title: Acute atrial arrhythmogenicity and altered Ca(2+) homeostasis in murine RyR2-P2328S hearts.
Volume: 89
Issue: 4
Pages: 794-804
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Publication
35913125 | J:344111
   
First Author: Shen X
Year: 2022
Journal: Elife
Title: Prolonged β-adrenergic stimulation disperses ryanodine receptor clusters in cardiomyocytes and has implications for heart failure.
Volume: 11
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Publication
21680895 | J:186604
First Author: Liu N
Year: 2011
Journal: Circ Res
Title: Short communication: flecainide exerts an antiarrhythmic effect in a mouse model of catecholaminergic polymorphic ventricular tachycardia by increasing the threshold for triggered activity.
Volume: 109
Issue: 3
Pages: 291-5
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17872467 | J:142170
First Author: Cerrone M
Year: 2007
Journal: Circ Res
Title: Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia.
Volume: 101
Issue: 10
Pages: 1039-48
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22711277 | J:202205
First Author: Neco P
Year: 2012
Journal: Circulation
Title: Paradoxical effect of increased diastolic Ca(2+) release and decreased sinoatrial node activity in a mouse model of catecholaminergic polymorphic ventricular tachycardia.
Volume: 126
Issue: 4
Pages: 392-401
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25524238 | J:284708
First Author: Maass K
Year: 2015
Journal: Stem Cells
Title: Isolation and characterization of embryonic stem cell-derived cardiac Purkinje cells.
Volume: 33
Issue: 4
Pages: 1102-12
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28065668 | J:254367
 
First Author: Alvarado FJ
Year: 2017
Journal: J Mol Cell Cardiol
Title: Ablation of the cardiac ryanodine receptor phospho-site Ser2808 does not alter the adrenergic response or the progression to heart failure in mice. Elimination of the genetic background as critical variable.
Volume: 103
Pages: 40-47
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12676814 | J:130644
First Author: Zhang T
Year: 2003
Journal: Circ Res
Title: The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure.
Volume: 92
Issue: 8
Pages: 912-9
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31051095 | J:293740
First Author: Wang Q
Year: 2019
Journal: FASEB J
Title: Two pools of IRE1α in cardiac and skeletal muscle cells.
Volume: 33
Issue: 8
Pages: 8892-8904
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26857906 | J:264908
First Author: Wu Y
Year: 2016
Journal: Circ Arrhythm Electrophysiol
Title: A Single Protein Kinase A or Calmodulin Kinase II Site Does Not Control the Cardiac Pacemaker Ca2+ Clock.
Volume: 9
Issue: 2
Pages: e003180
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Publication
19703963 | J:176786
First Author: Stevens SC
Year: 2009
Journal: J Physiol
Title: Intra-sarcoplasmic reticulum Ca2+ oscillations are driven by dynamic regulation of ryanodine receptor function by luminal Ca2+ in cardiomyocytes.
Volume: 587
Issue: Pt 20
Pages: 4863-72
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23295832 | J:212859
First Author: Faggioni M
Year: 2013
Journal: Circ Res
Title: Accelerated sinus rhythm prevents catecholaminergic polymorphic ventricular tachycardia in mice and in patients.
Volume: 112
Issue: 4
Pages: 689-97
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23856523 | J:213362
First Author: Bai Y
Year: 2013
Journal: Circ Res
Title: Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice.
Volume: 113
Issue: 5
Pages: 517-26
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21743453 | J:174541
First Author: Zhou Q
Year: 2011
Journal: Nat Med
Title: Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release.
Volume: 17
Issue: 8
Pages: 1003-9
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21673970 | J:174958
First Author: Fernández-Velasco M
Year: 2011
Journal: PLoS One
Title: RyRCa2+ leak limits cardiac Ca2+ window current overcoming the tonic effect of calmodulinin mice.
Volume: 6
Issue: 6
Pages: e20863
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27169737 | J:243948
First Author: Willis BC
Year: 2016
Journal: Circulation
Title: Constitutive Intracellular Na+ Excess in Purkinje Cells Promotes Arrhythmogenesis at Lower Levels of Stress Than Ventricular Myocytes From Mice With Catecholaminergic Polymorphic Ventricular Tachycardia.
Volume: 133
Issue: 24
Pages: 2348-59
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31591206 | J:280658
First Author: Pritchard HAT
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Nanoscale coupling of junctophilin-2 and ryanodine receptors regulates vascular smooth muscle cell contractility.
Volume: 116
Issue: 43
Pages: 21874-21881
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Publication
25245290 | J:220080
First Author: Saito H
Year: 2014
Journal: Biochem Biophys Res Commun
Title: K-rasG12V mediated lung tumor models identified three new quantitative trait loci modifying events post-K-ras mutation.
Volume: 452
Issue: 4
Pages: 1067-70
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28158491 | J:261092
First Author: Wullschleger M
Year: 2017
Journal: Cardiovasc Res
Title: Functional local crosstalk of inositol 1,4,5-trisphosphate receptor- and ryanodine receptor-dependent Ca2+ release in atrial cardiomyocytes.
Volume: 113
Issue: 5
Pages: 542-552
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Publication
8898078 | J:36013
First Author: Miyatake R
Year: 1996
Journal: FEBS Lett
Title: Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.
Volume: 395
Issue: 2-3
Pages: 123-6
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12777394 | J:85311
First Author: Most P
Year: 2003
Journal: J Biol Chem
Title: Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance.
Volume: 278
Issue: 36
Pages: 33809-17
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7876312 | J:23314
First Author: Giannini G
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