B0AT3 is a member of the solute carrier 6 (SLC6) transporter family. It transports glycine. Human B0AT3 (encoded by the SLC6A18 gene) is expressed in the kidney [, ]. Mutations in the SLC6A18 gene may contribute to the autosomal recessive disorder iminoglycinuria and its related disorder hyperglycinuria []. SLC6A18 or its neighbouring genes are associated with increased susceptibility to myocardial infarction [].
